kawain-2299 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
Similar Terms
Downloads & Tools

Genes

197 genes differentially expressed following the kawain-2299 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACSL5 acyl-CoA synthetase long-chain family member 5
AHNAK AHNAK nucleoprotein
ALDOB aldolase B, fructose-bisphosphate
ALK anaplastic lymphoma receptor tyrosine kinase
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
AP2B1 adaptor-related protein complex 2, beta 1 subunit
ARC activity-regulated cytoskeleton-associated protein
ARID5A AT rich interactive domain 5A (MRF1-like)
ASMT acetylserotonin O-methyltransferase
ATF6B activating transcription factor 6 beta
ATHL1 ATH1, acid trehalase-like 1 (yeast)
BST2 bone marrow stromal cell antigen 2
C17ORF59 chromosome 17 open reading frame 59
C19ORF66 chromosome 19 open reading frame 66
C22ORF46 chromosome 22 open reading frame 46
CA9 carbonic anhydrase IX
CAMK2B calcium/calmodulin-dependent protein kinase II beta
CCDC40 coiled-coil domain containing 40
CD52 CD52 molecule
CDC25A cell division cycle 25A
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CFHR2 complement factor H-related 2
CHRNA9 cholinergic receptor, nicotinic, alpha 9 (neuronal)
CHST5 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5
CLDN17 claudin 17
CNN1 calponin 1, basic, smooth muscle
COL1A2 collagen, type I, alpha 2
CSTF2T cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant
DFNB31 deafness, autosomal recessive 31
DGCR8 DGCR8 microprocessor complex subunit
DKK3 dickkopf WNT signaling pathway inhibitor 3
FAM155A family with sequence similarity 155, member A
FASLG Fas ligand (TNF superfamily, member 6)
FGF6 fibroblast growth factor 6
FKBP10 FK506 binding protein 10, 65 kDa
GABRD gamma-aminobutyric acid (GABA) A receptor, delta
GAS7 growth arrest-specific 7
GFER growth factor, augmenter of liver regeneration
GLT8D2 glycosyltransferase 8 domain containing 2
GMPR guanosine monophosphate reductase
GNGT1 guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1
GPR153 G protein-coupled receptor 153
GRIK2 glutamate receptor, ionotropic, kainate 2
IFI16 interferon, gamma-inducible protein 16
IFI27 interferon, alpha-inducible protein 27
IGL immunoglobulin lambda locus
IL1RN interleukin 1 receptor antagonist
KANK1 KN motif and ankyrin repeat domains 1
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1
LYVE1 lymphatic vessel endothelial hyaluronan receptor 1
LYZL6 lysozyme-like 6
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
MAPRE3 microtubule-associated protein, RP/EB family, member 3
MED25 mediator complex subunit 25
MEF2D myocyte enhancer factor 2D
MFAP3 microfibrillar-associated protein 3
NCAM1 neural cell adhesion molecule 1
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
NEUROD4 neuronal differentiation 4
NPM3 nucleophosmin/nucleoplasmin 3
NPY2R neuropeptide Y receptor Y2
OCA2 oculocutaneous albinism II
OLFML2A olfactomedin-like 2A
OMD osteomodulin
PAX2 paired box 2
PBX2 pre-B-cell leukemia homeobox 2
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PKP1 plakophilin 1
POU2F2 POU class 2 homeobox 2
PPFIBP2 PTPRF interacting protein, binding protein 2 (liprin beta 2)
PQLC2 PQ loop repeat containing 2
PRDM12 PR domain containing 12
PSAT1 phosphoserine aminotransferase 1
RHEB Ras homolog enriched in brain
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae)
RUNX1 runt-related transcription factor 1
SAA3P serum amyloid A3 pseudogene
SERHL2 serine hydrolase-like 2
SIGLEC8 sialic acid binding Ig-like lectin 8
SLPI secretory leukocyte peptidase inhibitor
SPAM1 sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding)
SPEG SPEG complex locus
SPINK1 serine peptidase inhibitor, Kazal type 1
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SRRT serrate, RNA effector molecule
ST6GALNAC5 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5
TM4SF5 transmembrane 4 L six family member 5
TMEM259 transmembrane protein 259
TRAIP TRAF interacting protein
TUBA4B tubulin, alpha 4b
U2AF2 U2 small nuclear RNA auxiliary factor 2
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2)
VIPR1 vasoactive intestinal peptide receptor 1
VPS16 vacuolar protein sorting 16 homolog (S. cerevisiae)
WIZ widely interspaced zinc finger motifs
ZNF155 zinc finger protein 155
ZNF175 zinc finger protein 175
ZNF589 zinc finger protein 589

decreased expression

Symbol Name
ACSL4 acyl-CoA synthetase long-chain family member 4
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
B9D2 B9 protein domain 2
C4ORF29 chromosome 4 open reading frame 29
CA5BP1 carbonic anhydrase VB pseudogene 1
CCP110 centriolar coiled coil protein 110kDa
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae)
CD83 CD83 molecule
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
DLST dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3
EFNA3 ephrin-A3
EHMT1 euchromatic histone-lysine N-methyltransferase 1
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
ERCC4 excision repair cross-complementation group 4
ERN2 endoplasmic reticulum to nucleus signaling 2
FAM169A family with sequence similarity 169, member A
FLRT3 fibronectin leucine rich transmembrane protein 3
GALT galactose-1-phosphate uridylyltransferase
GAMT guanidinoacetate N-methyltransferase
GINS4 GINS complex subunit 4 (Sld5 homolog)
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GNL3LP1 guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1
GPRIN2 G protein regulated inducer of neurite outgrowth 2
GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa
GUSBP3 glucuronidase, beta pseudogene 3
HAUS6 HAUS augmin-like complex, subunit 6
HELLS helicase, lymphoid-specific
HIST1H1D histone cluster 1, H1d
HNRNPUL2 heterogeneous nuclear ribonucleoprotein U-like 2
HP1BP3 heterochromatin protein 1, binding protein 3
IPP intracisternal A particle-promoted polypeptide
ITPKB inositol-trisphosphate 3-kinase B
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2
LYPLA2P1 lysophospholipase II pseudogene 1
MANBA mannosidase, beta A, lysosomal
MAP6D1 MAP6 domain containing 1
MBTD1 mbt domain containing 1
MED18 mediator complex subunit 18
METTL8 methyltransferase like 8
MGC12488
MPHOSPH8 M-phase phosphoprotein 8
MUC3A mucin 3A, cell surface associated
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive
NT5E 5'-nucleotidase, ecto (CD73)
OGFRL1 opioid growth factor receptor-like 1
PCDHA6 protocadherin alpha 6
PLA2G3 phospholipase A2, group III
PLEKHA6 pleckstrin homology domain containing, family A member 6
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
PMEL premelanosome protein
POLH polymerase (DNA directed), eta
PRR14L proline rich 14-like
PTK6 protein tyrosine kinase 6
RFWD3 ring finger and WD repeat domain 3
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RNF122 ring finger protein 122
SCD5 stearoyl-CoA desaturase 5
SCGB2A2 secretoglobin, family 2A, member 2
SLC16A7 solute carrier family 16 (monocarboxylate transporter), member 7
SLC25A40 solute carrier family 25, member 40
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
SNX16 sorting nexin 16
SOX12 SRY (sex determining region Y)-box 12
SPON2 spondin 2, extracellular matrix protein
SRD5A3 steroid 5 alpha-reductase 3
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma)
ST5 suppression of tumorigenicity 5
STAG3L1 stromal antigen 3-like 1 (pseudogene)
STAG3L4 stromal antigen 3-like 4 (pseudogene)
SUV39H2 suppressor of variegation 3-9 homolog 2 (Drosophila)
TEAD1 TEA domain family member 1 (SV40 transcriptional enhancer factor)
TESC tescalcin
TET3 tet methylcytosine dioxygenase 3
TEX40 testis expressed 40
TGFBI transforming growth factor, beta-induced, 68kDa
TRMT2B tRNA methyltransferase 2 homolog B (S. cerevisiae)
TWSG1 twisted gastrulation BMP signaling modulator 1
UBQLN4 ubiquilin 4
USB1 U6 snRNA biogenesis 1
USP18 ubiquitin specific peptidase 18
VASH2 vasohibin 2
VAX2 ventral anterior homeobox 2
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
ZNF12 zinc finger protein 12
ZNF573 zinc finger protein 573
ZNF611 zinc finger protein 611
ZNF652 zinc finger protein 652
ZNF721 zinc finger protein 721