kawain-3670 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
Similar Terms
Downloads & Tools

Genes

199 genes differentially expressed following the kawain-3670 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5
ADGRL3 adhesion G protein-coupled receptor L3
ADORA3 adenosine A3 receptor
ANGPT4 angiopoietin 4
ANXA10 annexin A10
AP2B1 adaptor-related protein complex 2, beta 1 subunit
APP amyloid beta (A4) precursor protein
ARMC4 armadillo repeat containing 4
ARSD arylsulfatase D
B9D1 B9 protein domain 1
BLZF1 basic leucine zipper nuclear factor 1
C10ORF10 chromosome 10 open reading frame 10
CADM3 cell adhesion molecule 3
CAT catalase
CCDC177 coiled-coil domain containing 177
CCDC57 coiled-coil domain containing 57
CDH9 cadherin 9, type 2 (T1-cadherin)
CDO1 cysteine dioxygenase type 1
CLEC4M C-type lectin domain family 4, member M
CNGA1 cyclic nucleotide gated channel alpha 1
CROCCP3 ciliary rootlet coiled-coil, rootletin pseudogene 3
CSF1R colony stimulating factor 1 receptor
CTIF CBP80/20-dependent translation initiation factor
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
CYTH3 cytohesin 3
DGCR2 DiGeorge syndrome critical region gene 2
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1)
ECM2 extracellular matrix protein 2, female organ and adipocyte specific
EGFR epidermal growth factor receptor
FABP3 fatty acid binding protein 3, muscle and heart
FBXO40 F-box protein 40
FKBP10 FK506 binding protein 10, 65 kDa
FLJ11710 uncharacterized protein FLJ11710
FN1 fibronectin 1
GAB1 GRB2-associated binding protein 1
GPC3 glypican 3
GPR85 G protein-coupled receptor 85
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
HNF1A HNF1 homeobox A
HOXD1 homeobox D1
ITGA7 integrin, alpha 7
KDM4B lysine (K)-specific demethylase 4B
KLRF1 killer cell lectin-like receptor subfamily F, member 1
KRT37 keratin 37, type I
LDHC lactate dehydrogenase C
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LIMK2 LIM domain kinase 2
LOC100294391 uncharacterized LOC100294391
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1
MAP3K13 mitogen-activated protein kinase kinase kinase 13
MBD2 methyl-CpG binding domain protein 2
MDM4 MDM4, p53 regulator
MOBP myelin-associated oligodendrocyte basic protein
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MTSS1L metastasis suppressor 1-like
MUC8 mucin 8
N4BP1 NEDD4 binding protein 1
NBR2 neighbor of BRCA1 gene 2 (non-protein coding)
NPM3 nucleophosmin/nucleoplasmin 3
OR2B6 olfactory receptor, family 2, subfamily B, member 6
PAX8 paired box 8
PDE4C phosphodiesterase 4C, cAMP-specific
PDPN podoplanin
PGLYRP4 peptidoglycan recognition protein 4
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PLA2G1B phospholipase A2, group IB (pancreas)
PRELP proline/arginine-rich end leucine-rich repeat protein
PRLH prolactin releasing hormone
PSG9 pregnancy specific beta-1-glycoprotein 9
S100A12 S100 calcium binding protein A12
SENP7 SUMO1/sentrin specific peptidase 7
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3
SFTPB surfactant protein B
SIRT4 sirtuin 4
SLC15A2 solute carrier family 15 (oligopeptide transporter), member 2
SLC24A2 solute carrier family 24 (sodium/potassium/calcium exchanger), member 2
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SMOX spermine oxidase
SPINK5 serine peptidase inhibitor, Kazal type 5
SRSF7 serine/arginine-rich splicing factor 7
STAT4 signal transducer and activator of transcription 4
STK16 serine/threonine kinase 16
TACC1 transforming, acidic coiled-coil containing protein 1
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TBC1D30 TBC1 domain family, member 30
TBX5 T-box 5
THRB thyroid hormone receptor, beta
THSD4 thrombospondin, type I, domain containing 4
THTPA thiamine triphosphatase
TMED9 transmembrane emp24 protein transport domain containing 9
TNK2 tyrosine kinase, non-receptor, 2
TRAC T cell receptor alpha constant
TRIM48 tripartite motif containing 48
TRIO trio Rho guanine nucleotide exchange factor
UNC13A unc-13 homolog A (C. elegans)
USP22 ubiquitin specific peptidase 22
UTY ubiquitously transcribed tetratricopeptide repeat containing, Y-linked
YBX2 Y box binding protein 2
ZBTB7A zinc finger and BTB domain containing 7A

decreased expression

Symbol Name
ACSS3 acyl-CoA synthetase short-chain family member 3
ADAP2 ArfGAP with dual PH domains 2
ALPP alkaline phosphatase, placental
ANKH ANKH inorganic pyrophosphate transport regulator
ARC activity-regulated cytoskeleton-associated protein
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
C7ORF43 chromosome 7 open reading frame 43
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2
CACNG4 calcium channel, voltage-dependent, gamma subunit 4
CAPN5 calpain 5
CARD8 caspase recruitment domain family, member 8
CDHR2 cadherin-related family member 2
CDK3 cyclin-dependent kinase 3
CDK5RAP2 CDK5 regulatory subunit associated protein 2
CDK6 cyclin-dependent kinase 6
CDON cell adhesion associated, oncogene regulated
CIDEC cell death-inducing DFFA-like effector c
CLCN6 chloride channel, voltage-sensitive 6
CUZD1 CUB and zona pellucida-like domains 1
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
ENOX1 ecto-NOX disulfide-thiol exchanger 1
EPN1 epsin 1
ERO1LB ERO1-like beta (S. cerevisiae)
FZD8 frizzled class receptor 8
GAS8 growth arrest-specific 8
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GMIP GEM interacting protein
GPR3 G protein-coupled receptor 3
HIST1H2AI histone cluster 1, H2ai
HIST1H3G histone cluster 1, H3g
HMGB3P1 high mobility group box 3 pseudogene 1
IFI6 interferon, alpha-inducible protein 6
IL22 interleukin 22
INF2 inverted formin, FH2 and WH2 domain containing
IQCC IQ motif containing C
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase
LIME1 Lck interacting transmembrane adaptor 1
LPPR4 lipid phosphate phosphatase-related protein type 4
LRRC61 leucine rich repeat containing 61
MEGF8 multiple EGF-like-domains 8
MN1 meningioma (disrupted in balanced translocation) 1
MTMR12 myotubularin related protein 12
MYL5 myosin, light chain 5, regulatory
MYLK myosin light chain kinase
NACA2 nascent polypeptide-associated complex alpha subunit 2
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NIPAL2 NIPA-like domain containing 2
NPR3 natriuretic peptide receptor 3
PADI1 peptidyl arginine deiminase, type I
PARD6A par-6 family cell polarity regulator alpha
PCBP4 poly(rC) binding protein 4
PCSK7 proprotein convertase subtilisin/kexin type 7
PID1 phosphotyrosine interaction domain containing 1
PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q
PLD2 phospholipase D2
PLD3 phospholipase D family, member 3
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PODNL1 podocan-like 1
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PPP2R3B protein phosphatase 2, regulatory subunit B'', beta
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
PRF1 perforin 1 (pore forming protein)
PRR15L proline rich 15-like
PRSS8 protease, serine, 8
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTK6 protein tyrosine kinase 6
RAB36 RAB36, member RAS oncogene family
RAB4B RAB4B, member RAS oncogene family
RAD54L RAD54-like (S. cerevisiae)
RPRM reprimo, TP53 dependent G2 arrest mediator candidate
RUNDC3B RUN domain containing 3B
SAYSD1 SAYSVFN motif domain containing 1
SCARA3 scavenger receptor class A, member 3
SCN8A sodium channel, voltage gated, type VIII alpha subunit
SETD1A SET domain containing 1A
SGK2 serum/glucocorticoid regulated kinase 2
SH3BGR SH3 domain binding glutamate-rich protein
SIRT6 sirtuin 6
SLC22A18 solute carrier family 22, member 18
SP4 Sp4 transcription factor
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TEP1 telomerase-associated protein 1
TFCP2L1 transcription factor CP2-like 1
TIMP4 TIMP metallopeptidase inhibitor 4
TINF2 TERF1 (TRF1)-interacting nuclear factor 2
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TMEM212 transmembrane protein 212
TRDMT1 tRNA aspartic acid methyltransferase 1
VN1R1 vomeronasal 1 receptor 1
WFDC2 WAP four-disulfide core domain 2
WNT10B wingless-type MMTV integration site family, member 10B
WT1-AS WT1 antisense RNA
ZC3H12A zinc finger CCCH-type containing 12A
ZNF276 zinc finger protein 276
ZNF639 zinc finger protein 639
ZNF749 zinc finger protein 749
ZNF862 zinc finger protein 862