kcnq1 Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description potassium channel, voltage gated KQT-like subfamily Q, member 1|This gene encodes a voltage-gated potassium channel required for repolarization phase of the cardiac action potential. This protein can form heteromultimers with two other potassium channel proteins, KCNE1 and KCNE3. Mutations in this gene are associated with hereditary long QT syndrome 1 (also known as Romano-Ward syndrome), Jervell and Lange-Nielsen syndrome, and familial atrial fibrillation. This gene exhibits tissue-specific imprinting, with preferential expression from the maternal allele in some tissues, and biallelic expression in others. This gene is located in a region of chromosome 11 amongst other imprinted genes that are associated with Beckwith-Wiedemann syndrome (BWS), and itself has been shown to be disrupted by chromosomal rearrangements in patients with BWS. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2011] (NCBI Entrez Gene Database, 3784)
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Genes

35 genes co-occuring with the biological term kcnq1 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
AKAP9 A kinase (PRKA) anchor protein 9
ANK2 ankyrin 2, neuronal
CAMK1D calcium/calmodulin-dependent protein kinase ID
CAV3 caveolin 3
CDC123 cell division cycle 123
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1
CDKN2A cyclin-dependent kinase inhibitor 2A
DCN decorin
DERL1 derlin 1
ERG v-ets avian erythroblastosis virus E26 oncogene homolog
HHEX hematopoietically expressed homeobox
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2
INS insulin
KCNE1 potassium channel, voltage gated subfamily E regulatory beta subunit 1
KCNE2 potassium channel, voltage gated subfamily E regulatory beta subunit 2
KCNE3 potassium channel, voltage gated subfamily E regulatory beta subunit 3
KCNE4 potassium channel, voltage gated subfamily E regulatory beta subunit 4
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KCNMB1 potassium channel subfamily M regulatory beta subunit 1
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1
KCNQ2 potassium channel, voltage gated KQT-like subfamily Q, member 2
KCNQ3 potassium channel, voltage gated KQT-like subfamily Q, member 3
KCNQ4 potassium channel, voltage gated KQT-like subfamily Q, member 4
KCNQ5 potassium channel, voltage gated KQT-like subfamily Q, member 5
KLF14 Kruppel-like factor 14
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
NAP1L4 nucleosome assembly protein 1-like 4
NPPA natriuretic peptide A
OSBPL5 oxysterol binding protein-like 5
PPARG peroxisome proliferator-activated receptor gamma
PTPRD protein tyrosine phosphatase, receptor type, D
SCN5A sodium channel, voltage gated, type V alpha subunit
SLC30A8 solute carrier family 30 (zinc transporter), member 8
WWOX WW domain containing oxidoreductase