keloid Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description A tough heaped-up scar that rises quite abruptly above the rest of the skin. It is irregularly shaped and tends to enlarge progressively. Keloids arise when there is too much collagen formed in the dermis during the repair of connective tissue. (BRENDA Tissue and Enzyme Source Ontology, BTO_0003669)
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Genes

58 genes co-occuring with the biological term keloid in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
AKT1 v-akt murine thymoma viral oncogene homolog 1
ANXA2 annexin A2
CCL2 chemokine (C-C motif) ligand 2
CDK11B cyclin-dependent kinase 11B
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
COMP cartilage oligomeric matrix protein
CTGF connective tissue growth factor
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
FASLG Fas ligand (TNF superfamily, member 6)
FBN1 fibrillin 1
FOS FBJ murine osteosarcoma viral oncogene homolog
FOSB FBJ murine osteosarcoma viral oncogene homolog B
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
GNAI3 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3
HDGF hepatoma-derived growth factor
HLA-DRB5 major histocompatibility complex, class II, DR beta 5
HSPB6 heat shock protein, alpha-crystallin-related, B6
IGF1 insulin-like growth factor 1 (somatomedin C)
IL17A interleukin 17A
IL6 interleukin 6
IL6R interleukin 6 receptor
JUN jun proto-oncogene
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MIR196A1 microRNA 196a-1
MIR196A2 microRNA 196a-2
MIR21 microRNA 21
MMP2 matrix metallopeptidase 2
MT1A metallothionein 1A
MT1F metallothionein 1F
MT1G metallothionein 1G
MT1X metallothionein 1X
MT2A metallothionein 2A
MYH10 myosin, heavy chain 10, non-muscle
MYH9 myosin, heavy chain 9, non-muscle
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
POSTN periostin, osteoblast specific factor
RSPO2 R-spondin 2
RUNX3 runt-related transcription factor 3
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SFRP2 secreted frizzled-related protein 2
SKOR1 SKI family transcriptional corepressor 1
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
SP1 Sp1 transcription factor
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
TGFB1 transforming growth factor, beta 1
TGFBR1 transforming growth factor, beta receptor 1
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TLR6 toll-like receptor 6
TLR7 toll-like receptor 7
TLR8 toll-like receptor 8
TMSB4X thymosin beta 4, X-linked
TP53 tumor protein p53
TP63 tumor protein p63
VCAN versican
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VEGFA vascular endothelial growth factor A
WNT3A wingless-type MMTV integration site family, member 3A