keratan sulfate biosynthetic process Gene Set
Dataset
GO Biological Process Annotations 2023
Category
structural or functional annotations
Type
biological process
Description
The chemical reactions and pathways resulting in the formation of keratan sulfate, a glycosaminoglycan with repeat units consisting of beta-1,4-linked D-galactopyranosyl-beta-(1,4)-N-acetyl-D-glucosamine 6-sulfate and with variable amounts of fucose, sialic acid and mannose units; keratan sulfate chains are covalently linked by a glycosidic attachment through the trisaccharide galactosyl-galactosyl-xylose to peptidyl-threonine or serine residues. (Gene Ontology , GO_0018146 )
External Link
http://amigo.geneontology.org/amigo/term/GO_0018146
Similar Terms
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Genes
16 genes participating in the keratan sulfate biosynthetic process biological process from the curated GO Biological Process Annotations 2023 dataset.
Symbol
Name
B3GNT1
B3GNT2
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
B3GNT3
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
B3GNT4
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
B3GNT7
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7
B4GALT4
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4
CHST1
carbohydrate (keratan sulfate Gal-6) sulfotransferase 1
CHST2
carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2
CHST5
carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5
CHST6
carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 6
SLC35D2
solute carrier family 35 (UDP-GlcNAc/UDP-glucose transporter), member D2
ST3GAL1
ST3 beta-galactoside alpha-2,3-sialyltransferase 1
ST3GAL2
ST3 beta-galactoside alpha-2,3-sialyltransferase 2
ST3GAL3
ST3 beta-galactoside alpha-2,3-sialyltransferase 3
ST3GAL4
ST3 beta-galactoside alpha-2,3-sialyltransferase 4
ST3GAL6
ST3 beta-galactoside alpha-2,3-sialyltransferase 6