keratoconjunctivitis Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores
Category disease or phenotype associations
Type disease
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Genes

335 genes co-occuring with the disease keratoconjunctivitis in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
CHKB choline kinase beta 1.56222
TAC4 tachykinin 4 (hemokinin) 1.48823
PDYN prodynorphin 1.41052
PSENEN presenilin enhancer gamma secretase subunit 1.3664
TNF tumor necrosis factor 1.31144
RNASE3 ribonuclease, RNase A family, 3 1.2813
LTF lactotransferrin 1.23169
JAG2 jagged 2 1.1541
OSGEP O-sialoglycoprotein endopeptidase 1.11477
PPP1R12A protein phosphatase 1, regulatory subunit 12A 1.07194
LYZ lysozyme 1.05303
LAGE3 L antigen family, member 3 1.03746
CD4 CD4 molecule 1.03704
CD79A CD79a molecule, immunoglobulin-associated alpha 1.03409
HSPG2 heparan sulfate proteoglycan 2 1.0265
GJB6 gap junction protein, beta 6, 30kDa 0.988535
S100A7 S100 calcium binding protein A7 0.97212
OPRM1 opioid receptor, mu 1 0.9696
TLR4 toll-like receptor 4 0.968341
IL1B interleukin 1, beta 0.921736
ICAM1 intercellular adhesion molecule 1 0.836017
TARBP2 TAR (HIV-1) RNA binding protein 2 0.835607
CCL17 chemokine (C-C motif) ligand 17 0.819206
NGF nerve growth factor (beta polypeptide) 0.803205
IRAK4 interleukin-1 receptor-associated kinase 4 0.793771
AIRE autoimmune regulator 0.780251
BRD9 bromodomain containing 9 0.777795
MMP9 matrix metallopeptidase 9 0.766759
VSIG4 V-set and immunoglobulin domain containing 4 0.763902
CASP14 caspase 14, apoptosis-related cysteine peptidase 0.758601
IL6 interleukin 6 0.737054
TP53RK TP53 regulating kinase 0.736243
TGFB1 transforming growth factor, beta 1 0.735838
SLC35D2 solute carrier family 35 (UDP-GlcNAc/UDP-glucose transporter), member D2 0.717635
TAC1 tachykinin, precursor 1 0.716425
FLG filaggrin 0.714408
FN1 fibronectin 1 0.705949
HMGB1 high mobility group box 1 0.703536
YRDC yrdC N(6)-threonylcarbamoyltransferase domain containing 0.673518
IL1A interleukin 1, alpha 0.667947
LYNX1 Ly6/neurotoxin 1 0.661594
IVL involucrin 0.661197
AQP5 aquaporin 5 0.644981
STAB1 stabilin 1 0.642221
CD40 CD40 molecule, TNF receptor superfamily member 5 0.632384
IFNA4 interferon, alpha 4 0.627672
CD68 CD68 molecule 0.625711
LOR loricrin 0.621792
SRCIN1 SRC kinase signaling inhibitor 1 0.607714
PADI1 peptidyl arginine deiminase, type I 0.607323
TLR3 toll-like receptor 3 0.604201
TNFSF18 tumor necrosis factor (ligand) superfamily, member 18 0.60147
CMA1 chymase 1, mast cell 0.586276
VCAM1 vascular cell adhesion molecule 1 0.581606
HACD3 3-hydroxyacyl-CoA dehydratase 3 0.581606
ADSL adenylosuccinate lyase 0.56722
TRIM21 tripartite motif containing 21 0.563335
ICAM3 intercellular adhesion molecule 3 0.559062
TSLP thymic stromal lymphopoietin 0.558674
IRAK1BP1 interleukin-1 receptor-associated kinase 1 binding protein 1 0.553627
RGPD1 RANBP2-like and GRIP domain containing 1 0.547419
TLR5 toll-like receptor 5 0.541217
EDA ectodysplasin A 0.535409
POMC proopiomelanocortin 0.529994
NBAS neuroblastoma amplified sequence 0.529608
HRC histidine rich calcium binding protein 0.52729
SUMF2 sulfatase modifying factor 2 0.525746
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.519575
LACRT lacritin 0.517649
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) 0.50689
DNTT DNA nucleotidylexotransferase 0.506507
MED4 mediator complex subunit 4 0.505739
TIMP1 TIMP metallopeptidase inhibitor 1 0.505356
MUC5B mucin 5B, oligomeric mucus/gel-forming 0.498467
CCL2 chemokine (C-C motif) ligand 2 0.494266
ITSN2 intersectin 2 0.491597
IL4 interleukin 4 0.483985
GOT1 glutamic-oxaloacetic transaminase 1, soluble 0.482844
AOAH acyloxyacyl hydrolase (neutrophil) 0.478668
CXCL10 chemokine (C-X-C motif) ligand 10 0.477909
DGKQ diacylglycerol kinase, theta 110kDa 0.476014
TLR2 toll-like receptor 2 0.473361
EPX eosinophil peroxidase 0.472604
PADI3 peptidyl arginine deiminase, type III 0.462016
CCL22 chemokine (C-C motif) ligand 22 0.459751
CXCL8 chemokine (C-X-C motif) ligand 8 0.459373
ALB albumin 0.457864
MSR1 macrophage scavenger receptor 1 0.456732
NPPB natriuretic peptide B 0.454093
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial 0.453716
S100A9 S100 calcium binding protein A9 0.449194
PHIP pleckstrin homology domain interacting protein 0.447311
TLR9 toll-like receptor 9 0.445052
CD274 CD274 molecule 0.442418
MMP21 matrix metallopeptidase 21 0.440914
UACA uveal autoantigen with coiled-coil domains and ankyrin repeats 0.437906
CCL11 chemokine (C-C motif) ligand 11 0.436026
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta 0.430017
KLF4 Kruppel-like factor 4 (gut) 0.429266
CHIA chitinase, acidic 0.424765
LSAMP limbic system-associated membrane protein 0.42364
RANGAP1 Ran GTPase activating protein 1 0.423265
FASLG Fas ligand (TNF superfamily, member 6) 0.421765
BPIFA2 BPI fold containing family A, member 2 0.419517
TNPO3 transportin 3 0.418019
PSIP1 PC4 and SFRS1 interacting protein 1 0.418019
E2F7 E2F transcription factor 7 0.410535
DSG3 desmoglein 3 0.410161
RNASE7 ribonuclease, RNase A family, 7 0.408292
SASH1 SAM and SH3 domain containing 1 0.406798
CD46 CD46 molecule, complement regulatory protein 0.406425
CXCL9 chemokine (C-X-C motif) ligand 9 0.405305
MARVELD2 MARVEL domain containing 2 0.404931
MMP2 matrix metallopeptidase 2 0.403064
JAK2 Janus kinase 2 0.40008
RNASEH2A ribonuclease H2, subunit A 0.391885
HPX hemopexin 0.387794
EMC3 ER membrane protein complex subunit 3 0.386308
PRF1 perforin 1 (pore forming protein) 0.386308
SCARF1 scavenger receptor class F, member 1 0.385565
VSX1 visual system homeobox 1 0.385193
HBEGF heparin-binding EGF-like growth factor 0.384451
MYD88 myeloid differentiation primary response 88 0.384451
SLC22A7 solute carrier family 22 (organic anion transporter), member 7 0.383337
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) 0.379256
NR1H3 nuclear receptor subfamily 1, group H, member 3 0.378885
KDELR1 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 0.377402
CCR3 chemokine (C-C motif) receptor 3 0.37629
STT3A STT3A, subunit of the oligosaccharyltransferase complex (catalytic) 0.374809
SPRR1B small proline-rich protein 1B 0.374809
F2RL1 coagulation factor II (thrombin) receptor-like 1 0.371847
PSEN2 presenilin 2 0.369628
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 0.366301
NELFCD negative elongation factor complex member C/D 0.361502
STAB2 stabilin 2 0.359289
ILVBL ilvB (bacterial acetolactate synthase)-like 0.354499
CD93 CD93 molecule 0.353395
SCARB2 scavenger receptor class B, member 2 0.352291
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 0.348981
CD40LG CD40 ligand 0.347144
CLC Charcot-Leyden crystal galectin 0.34384
LIPA lipase A, lysosomal acid, cholesterol esterase 0.339806
AREG amphiregulin 0.339073
KRT14 keratin 14, type I 0.339073
CD36 CD36 molecule (thrombospondin receptor) 0.336876
HLA-C major histocompatibility complex, class I, C 0.336876
CERK ceramide kinase 0.32993
DTNA dystrobrevin, alpha 0.321909
ARSI arylsulfatase family, member I 0.321545
KCP kielin/chordin-like protein 0.317909
MAP3K8 mitogen-activated protein kinase kinase kinase 8 0.317909
ACKR1 atypical chemokine receptor 1 (Duffy blood group) 0.316092
MPO myeloperoxidase 0.30848
GRASP GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein 0.304503
CD200 CD200 molecule 0.303781
PRKACB protein kinase, cAMP-dependent, catalytic, beta 0.303059
CCL8 chemokine (C-C motif) ligand 8 0.300894
WARS tryptophanyl-tRNA synthetase 0.300533
TARS2 threonyl-tRNA synthetase 2, mitochondrial (putative) 0.300173
CASD1 CAS1 domain containing 1 0.298731
SCARB1 scavenger receptor class B, member 1 0.297651
SACK1H scaffolding CK1 anchoring protein H 0.296571
MAPK8 mitogen-activated protein kinase 8 0.296211
KRT10 keratin 10, type I 0.294413
S100A8 S100 calcium binding protein A8 0.292257
GPR135 G protein-coupled receptor 135 0.291898
MBD5 methyl-CpG binding domain protein 5 0.290821
CCL20 chemokine (C-C motif) ligand 20 0.290462
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6 0.289744
KCNAB2 potassium channel, voltage gated subfamily A regulatory beta subunit 2 0.285802
KRT1 keratin 1, type II 0.283655
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.283655
MMP1 matrix metallopeptidase 1 0.280082
MMP8 matrix metallopeptidase 8 0.279367
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal) 0.279011
IL10 interleukin 10 0.276514
TNC tenascin C 0.275089
SLC39A6 solute carrier family 39 (zinc transporter), member 6 0.274376
XDH xanthine dehydrogenase 0.271174
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 0.268332
GJB4 gap junction protein, beta 4, 30.3kDa 0.267977
AQP3 aquaporin 3 (Gill blood group) 0.267622
CABIN1 calcineurin binding protein 1 0.265494
FFAR4 free fatty acid receptor 4 0.26266
DKK4 dickkopf WNT signaling pathway inhibitor 4 0.260538
KDM6B lysine (K)-specific demethylase 6B 0.25983
CCL7 chemokine (C-C motif) ligand 7 0.257005
TGM3 transglutaminase 3 0.254536
TANK TRAF family member-associated NFKB activator 0.253831
MMP13 matrix metallopeptidase 13 0.25207
FAM167A family with sequence similarity 167, member A 0.251718
RPLP0 ribosomal protein, large, P0 0.247852
MMP3 matrix metallopeptidase 3 0.245046
RANBP2 RAN binding protein 2 0.244345
KERA keratocan 0.243995
PRSS21 protease, serine, 21 (testisin) 0.242595
IL1R1 interleukin 1 receptor, type I 0.242245
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.240497
CD86 CD86 molecule 0.23945
CLEC3A C-type lectin domain family 3, member A 0.234573
LCN1 lipocalin 1 0.23353
LDLR low density lipoprotein receptor 0.23353
TOLLIP toll interacting protein 0.231102
SYVN1 synovial apoptosis inhibitor 1, synoviolin 0.230755
CUL2 cullin 2 0.230409
CLEC2B C-type lectin domain family 2, member B 0.230063
NBPF1 neuroblastoma breakpoint family, member 1 0.229024
ARG1 arginase 1 0.227297
TRPC4 transient receptor potential cation channel, subfamily C, member 4 0.225573
SLCO1C1 solute carrier organic anion transporter family, member 1C1 0.225229
SCGB2A1 secretoglobin, family 2A, member 1 0.221108
IL17C interleukin 17C 0.218034
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 0.215653
CCL13 chemokine (C-C motif) ligand 13 0.212945
GLDC glycine dehydrogenase (decarboxylating) 0.211934
TWIST2 twist family bHLH transcription factor 2 0.211934
HDAC11 histone deacetylase 11 0.211934
JUN jun proto-oncogene 0.210253
FGF2 fibroblast growth factor 2 (basic) 0.209583
CLEC10A C-type lectin domain family 10, member A 0.208914
E2F6 E2F transcription factor 6 0.208914
IFNA1 interferon, alpha 1 0.205916
ICA1 islet cell autoantigen 1, 69kDa 0.204923
SLCO4A1 solute carrier organic anion transporter family, member 4A1 0.204923
OGFR opioid growth factor receptor 0.204923
ADSS adenylosuccinate synthase 0.204593
KRT12 keratin 12, type I 0.204263
CD1A CD1a molecule 0.203933
XPR1 xenotropic and polytropic retrovirus receptor 1 0.203604
IL2RA interleukin 2 receptor, alpha 0.203275
TLR1 toll-like receptor 1 0.201308
UCN urocortin 0.200982
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 0.199356
ABCA12 ATP-binding cassette, sub-family A (ABC1), member 12 0.199356
SOCS3 suppressor of cytokine signaling 3 0.196779
CXCL11 chemokine (C-X-C motif) ligand 11 0.195183
NPS neuropeptide S 0.193915
ADCY9 adenylate cyclase 9 0.193285
DCXR dicarbonyl/L-xylulose reductase 0.193285
IRF5 interferon regulatory factor 5 0.192657
FABP7 fatty acid binding protein 7, brain 0.191097
GAS1 growth arrest-specific 1 0.188938
TIMP2 TIMP metallopeptidase inhibitor 2 0.18651
SLURP1 secreted LY6/PLAUR domain containing 1 0.184424
IL13 interleukin 13 0.183835
BANK1 B-cell scaffold protein with ankyrin repeats 1 0.181798
CPVL carboxypeptidase, vitellogenic-like 0.18151
CD209 CD209 molecule 0.18151
CORO1A coronin, actin binding protein, 1A 0.180652
ZP3 zona pellucida glycoprotein 3 (sperm receptor) 0.179802
SHB Src homology 2 domain containing adaptor protein B 0.176485
TTR transthyretin 0.175411
PNMA1 paraneoplastic Ma antigen 1 0.173832
CARD8 caspase recruitment domain family, member 8 0.172291
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1 0.171785
MMD monocyte to macrophage differentiation-associated 0.170789
AMER1 APC membrane recruitment protein 1 0.170299
IRF3 interferon regulatory factor 3 0.168854
HIF3A hypoxia inducible factor 3, alpha subunit 0.168617
PDCD1LG2 programmed cell death 1 ligand 2 0.166995
IRAK3 interleukin-1 receptor-associated kinase 3 0.166995
MAPK14 mitogen-activated protein kinase 14 0.161912
PTGFR prostaglandin F receptor (FP) 0.161912
TBX2 T-box 2 0.161523
IFNA2 interferon, alpha 2 0.160203
SRC SRC proto-oncogene, non-receptor tyrosine kinase 0.158434
SIM2 single-minded family bHLH transcription factor 2 0.158097
CCNE1 cyclin E1 0.143637
BGN biglycan 0.142929
NR0B1 nuclear receptor subfamily 0, group B, member 1 0.142866
SLC6A1 solute carrier family 6 (neurotransmitter transporter), member 1 0.13954
AP1M2 adaptor-related protein complex 1, mu 2 subunit 0.136506
TACR1 tachykinin receptor 1 0.136386
AP2M1 adaptor-related protein complex 2, mu 1 subunit 0.135745
FOXD3 forkhead box D3 0.135736
CSH1 chorionic somatomammotropin hormone 1 (placental lactogen) 0.135595
MLX MLX, MAX dimerization protein 0.135159
CSH2 chorionic somatomammotropin hormone 2 0.135078
TAT tyrosine aminotransferase 0.134997
OR6B2 olfactory receptor, family 6, subfamily B, member 2 0.13443
GRHL1 grainyhead-like 1 (Drosophila) 0.134154
PLAUR plasminogen activator, urokinase receptor 0.133516
PRAME preferentially expressed antigen in melanoma 0.133236
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.131867
OR10K1 olfactory receptor, family 10, subfamily K, member 1 0.13119
SEBOX SEBOX homeobox 0.130304
ADCY2 adenylate cyclase 2 (brain) 0.12943
CORT cortistatin 0.127488
FSCN3 fascin actin-bundling protein 3, testicular 0.12685
CST3 cystatin C 0.126182
SFTPB surfactant protein B 0.125338
FSCN2 fascin actin-bundling protein 2, retinal 0.125241
CXCL2 chemokine (C-X-C motif) ligand 2 0.122777
TES testin LIM domain protein 0.122692
PLA2G1B phospholipase A2, group IB (pancreas) 0.122029
SSB Sjogren syndrome antigen B (autoantigen La) 0.119152
CRYZ crystallin, zeta (quinone reductase) 0.119083
SIGLEC10 sialic acid binding Ig-like lectin 10 0.118707
JUNB jun B proto-oncogene 0.118286
AARS alanyl-tRNA synthetase 0.118251
SALL1 spalt-like transcription factor 1 0.117607
FSCN1 fascin actin-bundling protein 1 0.11757
IFNL1 interferon, lambda 1 0.117461
ANG angiogenin, ribonuclease, RNase A family, 5 0.117388
CD3E CD3e molecule, epsilon (CD3-TCR complex) 0.117315
BCAN brevican 0.116908
LY75 lymphocyte antigen 75 0.116188
FADD Fas (TNFRSF6)-associated via death domain 0.115916
PLK2 polo-like kinase 2 0.115916
NPTXR neuronal pentraxin receptor 0.115328
C3AR1 complement component 3a receptor 1 0.114807
IQGAP1 IQ motif containing GTPase activating protein 1 0.113777
TNIP1 TNFAIP3 interacting protein 1 0.113649
CCL27 chemokine (C-C motif) ligand 27 0.113607
PRKD1 protein kinase D1 0.113607
MIRLET7B microRNA let-7b 0.112881
GLUL glutamate-ammonia ligase 0.112837
CTGF connective tissue growth factor 0.11253
TRH thyrotropin-releasing hormone 0.112354
CRHR2 corticotropin releasing hormone receptor 2 0.111823
PNP purine nucleoside phosphorylase 0.111687
TRIM37 tripartite motif containing 37 0.111551
CCL4 chemokine (C-C motif) ligand 4 0.111506
MT3 metallothionein 3 0.111371
IGFBP7 insulin-like growth factor binding protein 7 0.11128
MRI1 methylthioribose-1-phosphate isomerase 1 0.111235
GPBAR1 G protein-coupled bile acid receptor 1 0.111235
POU5F1B POU class 5 homeobox 1B 0.111054
SCN2A sodium channel, voltage gated, type II alpha subunit 0.110822
ARPP21 cAMP-regulated phosphoprotein, 21kDa 0.110403
KRT15 keratin 15, type I 0.110124
NRTN neurturin 0.110124
SCAI suppressor of cancer cell invasion 0.110077
LGALS9 lectin, galactoside-binding, soluble, 9 0.110077
BOC BOC cell adhesion associated, oncogene regulated 0.109838