keratopathy Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores
Category disease or phenotype associations
Type disease
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Genes

121 genes co-occuring with the disease keratopathy in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
PBK PDZ binding kinase 1.9577
FBXO7 F-box protein 7 1.78444
MBD5 methyl-CpG binding domain protein 5 1.635
PAX6 paired box 6 1.55158
FAM46D family with sequence similarity 46, member D 1.54937
CTSF cathepsin F 1.35376
TAC1 tachykinin, precursor 1 1.21998
TNC tenascin C 1.19532
DHX9 DEAH (Asp-Glu-Ala-His) box helicase 9 1.04083
FN1 fibronectin 1 1.00119
IGF1 insulin-like growth factor 1 (somatomedin C) 0.921736
NID2 nidogen 2 (osteonidogen) 0.917199
OGFR opioid growth factor receptor 0.894179
KERA keratocan 0.885569
KRT12 keratin 12, type I 0.874919
IGHA2 immunoglobulin heavy constant alpha 2 (A2m marker) 0.84585
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) 0.839296
FBN1 fibrillin 1 0.833968
MMP10 matrix metallopeptidase 10 0.831099
LACRT lacritin 0.797052
NID1 nidogen 1 0.781479
KIF21A kinesin family member 21A 0.74436
ITK IL2-inducible T-cell kinase 0.737865
TGFB2 transforming growth factor, beta 2 0.725311
DCN decorin 0.691495
MUC16 mucin 16, cell surface associated 0.685491
FBLIM1 filamin binding LIM protein 1 0.681894
JCHAIN joining chain of multimeric IgA and IgM 0.671925
IL1A interleukin 1, alpha 0.647743
BGN biglycan 0.644192
TGFBI transforming growth factor, beta-induced, 68kDa 0.6214
TJP1 tight junction protein 1 0.608494
AIRE autoimmune regulator 0.603811
POU2F1 POU class 2 homeobox 1 0.590169
SPATA21 spermatogenesis associated 21 0.578883
DR1 down-regulator of transcription 1, TBP-binding (negative cofactor 2) 0.553627
LCN1 lipocalin 1 0.526132
FBLN2 fibulin 2 0.52536
PHOX2A paired-like homeobox 2a 0.508041
LCAT lecithin-cholesterol acyltransferase 0.50689
UBIAD1 UbiA prenyltransferase domain containing 1 0.506507
PTPRF protein tyrosine phosphatase, receptor type, F 0.480566
LAX1 lymphocyte transmembrane adaptor 1 0.466172
CORO1A coronin, actin binding protein, 1A 0.464283
CSPG5 chondroitin sulfate proteoglycan 5 (neuroglycan C) 0.457109
TIMP1 TIMP metallopeptidase inhibitor 1 0.446558
SMC3 structural maintenance of chromosomes 3 0.443923
HLA-DMA major histocompatibility complex, class II, DM alpha 0.430393
HLA-C major histocompatibility complex, class I, C 0.428891
NGF nerve growth factor (beta polypeptide) 0.416896
SRRM1 serine/arginine repetitive matrix 1 0.41465
DCXR dicarbonyl/L-xylulose reductase 0.40008
MMP9 matrix metallopeptidase 9 0.398589
MIP major intrinsic protein of lens fiber 0.398216
B2M beta-2-microglobulin 0.382594
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) 0.378885
ACOT13 acyl-CoA thioesterase 13 0.368888
STAP2 signal transducing adaptor family member 2 0.359657
PEX19 peroxisomal biogenesis factor 19 0.357077
ANXA2 annexin A2 0.357077
CHMP2A charged multivesicular body protein 2A 0.35082
ADAR adenosine deaminase, RNA-specific 0.348246
DNTT DNA nucleotidylexotransferase 0.325187
PRB3 proline-rich protein BstNI subfamily 3 0.321181
PIGR polymeric immunoglobulin receptor 0.318635
HBEGF heparin-binding EGF-like growth factor 0.316092
VSX1 visual system homeobox 1 0.30848
FLNB filamin B, beta 0.307033
TMSB4X thymosin beta 4, X-linked 0.304864
MATK megakaryocyte-associated tyrosine kinase 0.30342
NEB nebulin 0.294053
CYP4V2 cytochrome P450, family 4, subfamily V, polypeptide 2 0.293694
MMP2 matrix metallopeptidase 2 0.292616
IFITM2 interferon induced transmembrane protein 2 0.28831
BMP4 bone morphogenetic protein 4 0.287235
CR2 complement component (3d/Epstein Barr virus) receptor 2 0.284013
COL4A1 collagen, type IV, alpha 1 0.278297
TGFB1 transforming growth factor, beta 1 0.275445
NOVA2 neuro-oncological ventral antigen 2 0.261599
TIE1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1 0.251366
MAP1B microtubule-associated protein 1B 0.251015
CHD7 chromodomain helicase DNA binding protein 7 0.245396
EGFR epidermal growth factor receptor 0.241196
DNAH8 dynein, axonemal, heavy chain 8 0.233878
CTSS cathepsin S 0.231448
EFS embryonal Fyn-associated substrate 0.230409
CDH2 cadherin 2, type 1, N-cadherin (neuronal) 0.226262
AQP5 aquaporin 5 0.225573
SEBOX SEBOX homeobox 0.223165
CNTN2 contactin 2 (axonal) 0.210253
NDUFS3 NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase) 0.207245
ALB albumin 0.201308
AQP3 aquaporin 3 (Gill blood group) 0.19582
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 0.195501
LAMB2 laminin, beta 2 (laminin S) 0.194865
GYPE glycophorin E (MNS blood group) 0.191408
MMP13 matrix metallopeptidase 13 0.188938
TGM4 transglutaminase 4 0.188326
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) 0.177029
LOXL1 lysyl oxidase-like 1 0.174093
GJA1 gap junction protein, alpha 1, 43kDa 0.172799
LUM lumican 0.167452
NF2 neurofibromin 2 (merlin) 0.165874
CXCL8 chemokine (C-X-C motif) ligand 8 0.160203
RNASE3 ribonuclease, RNase A family, 3 0.158605
CD68 CD68 molecule 0.158434
OR10K2 olfactory receptor, family 10, subfamily K, member 2 0.157765
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) 0.144134
DES desmin 0.143498
VCAN versican 0.143492
TGFB3 transforming growth factor, beta 3 0.143253
COX5A cytochrome c oxidase subunit Va 0.143235
CD34 CD34 molecule 0.143222
ENO1 enolase 1, (alpha) 0.142658
CCR1 chemokine (C-C motif) receptor 1 0.142493
CLU clusterin 0.142311
AQP2 aquaporin 2 (collecting duct) 0.142216
HLA-G major histocompatibility complex, class I, G 0.142207
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) 0.141828
C6ORF25 chromosome 6 open reading frame 25 0.141749
IL7R interleukin 7 receptor 0.141586