| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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195 genes differentially expressed following the ketanserin-1593 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACAN | aggrecan |
| ADAMTS2 | ADAM metallopeptidase with thrombospondin type 1 motif, 2 |
| ADM | adrenomedullin |
| AHR | aryl hydrocarbon receptor |
| ALPK1 | alpha-kinase 1 |
| ANKRD12 | ankyrin repeat domain 12 |
| APOBEC3C | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C |
| BPI | bactericidal/permeability-increasing protein |
| CA6 | carbonic anhydrase VI |
| CA9 | carbonic anhydrase IX |
| CACFD1 | calcium channel flower domain containing 1 |
| CAPN10 | calpain 10 |
| CASP9 | caspase 9, apoptosis-related cysteine peptidase |
| CCPG1 | cell cycle progression 1 |
| CD2BP2 | CD2 (cytoplasmic tail) binding protein 2 |
| CD86 | CD86 molecule |
| CMTR1 | cap methyltransferase 1 |
| CNNM2 | cyclin and CBS domain divalent metal cation transport mediator 2 |
| CPD | carboxypeptidase D |
| CXCR4 | chemokine (C-X-C motif) receptor 4 |
| CYB561 | cytochrome b561 |
| DAXX | death-domain associated protein |
| EGR1 | early growth response 1 |
| EGR3 | early growth response 3 |
| ELF4 | E74-like factor 4 (ets domain transcription factor) |
| ELK1 | ELK1, member of ETS oncogene family |
| FAM214B | family with sequence similarity 214, member B |
| FAM63A | family with sequence similarity 63, member A |
| FCGRT | Fc fragment of IgG, receptor, transporter, alpha |
| FLNB | filamin B, beta |
| FLNC | filamin C, gamma |
| FOLR1 | folate receptor 1 (adult) |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) |
| GAP43 | growth associated protein 43 |
| GATA2 | GATA binding protein 2 |
| HUS1 | HUS1 checkpoint homolog (S. pombe) |
| IDH3G | isocitrate dehydrogenase 3 (NAD+) gamma |
| IMPAD1 | inositol monophosphatase domain containing 1 |
| JUN | jun proto-oncogene |
| KLHDC4 | kelch domain containing 4 |
| LAD1 | ladinin 1 |
| LPAR1 | lysophosphatidic acid receptor 1 |
| MAML3 | mastermind-like 3 (Drosophila) |
| MAPK10 | mitogen-activated protein kinase 10 |
| MOSPD2 | motile sperm domain containing 2 |
| MPPE1 | metallophosphoesterase 1 |
| MRC2 | mannose receptor, C type 2 |
| MYO1C | myosin IC |
| NEBL | nebulette |
| NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) |
| PAM | peptidylglycine alpha-amidating monooxygenase |
| PECAM1 | platelet/endothelial cell adhesion molecule 1 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
| PICALM | phosphatidylinositol binding clathrin assembly protein |
| PIDD1 | p53-induced death domain protein 1 |
| PIK3C2B | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta |
| PKD2L1 | polycystic kidney disease 2-like 1 |
| PLEKHO1 | pleckstrin homology domain containing, family O member 1 |
| PPP1R16B | protein phosphatase 1, regulatory subunit 16B |
| PSG9 | pregnancy specific beta-1-glycoprotein 9 |
| PTCRA | pre T-cell antigen receptor alpha |
| RANBP10 | RAN binding protein 10 |
| RFPL2 | ret finger protein-like 2 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) |
| RNF144A | ring finger protein 144A |
| SAV1 | salvador family WW domain containing protein 1 |
| SEPHS1 | selenophosphate synthetase 1 |
| SH3GL1 | SH3-domain GRB2-like 1 |
| SIDT2 | SID1 transmembrane family, member 2 |
| SIGLEC7 | sialic acid binding Ig-like lectin 7 |
| SLC25A24 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 |
| SMAP1 | small ArfGAP 1 |
| SMARCD1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1 |
| SMC5 | structural maintenance of chromosomes 5 |
| SMIM7 | small integral membrane protein 7 |
| SNTA1 | syntrophin, alpha 1 |
| SPN | sialophorin |
| SSX2IP | synovial sarcoma, X breakpoint 2 interacting protein |
| STAM2 | signal transducing adaptor molecule (SH3 domain and ITAM motif) 2 |
| STAT4 | signal transducer and activator of transcription 4 |
| SUGP1 | SURP and G patch domain containing 1 |
| SULT1B1 | sulfotransferase family, cytosolic, 1B, member 1 |
| SYNJ2 | synaptojanin 2 |
| TBC1D29 | TBC1 domain family, member 29 |
| THADA | thyroid adenoma associated |
| TPST1 | tyrosylprotein sulfotransferase 1 |
| TULP3 | tubby like protein 3 |
| UBE2I | ubiquitin-conjugating enzyme E2I |
| UBQLN4 | ubiquilin 4 |
| UNC119B | unc-119 homolog B (C. elegans) |
| UTRN | utrophin |
| ZNF408 | zinc finger protein 408 |
| ZNF44 | zinc finger protein 44 |
| ZNF839 | zinc finger protein 839 |
| ZSCAN26 | zinc finger and SCAN domain containing 26 |
| Symbol | Name |
|---|---|
| ACP2 | acid phosphatase 2, lysosomal |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 |
| BCCIP | BRCA2 and CDKN1A interacting protein |
| BCL2L14 | BCL2-like 14 (apoptosis facilitator) |
| BLMH | bleomycin hydrolase |
| BYSL | bystin-like |
| C12ORF29 | chromosome 12 open reading frame 29 |
| C19ORF24 | chromosome 19 open reading frame 24 |
| C6ORF47 | chromosome 6 open reading frame 47 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 |
| CD82 | CD82 molecule |
| CDT1 | chromatin licensing and DNA replication factor 1 |
| CLDND1 | claudin domain containing 1 |
| CLPB | ClpB homolog, mitochondrial AAA ATPase chaperonin |
| CLTCL1 | clathrin, heavy chain-like 1 |
| CNTD2 | cyclin N-terminal domain containing 2 |
| COMMD8 | COMM domain containing 8 |
| CORO2A | coronin, actin binding protein, 2A |
| CPNE1 | copine I |
| CPOX | coproporphyrinogen oxidase |
| CSTF3 | cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa |
| CTDP1 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 |
| DAAM1 | dishevelled associated activator of morphogenesis 1 |
| DDB1 | damage-specific DNA binding protein 1, 127kDa |
| DENND1A | DENN/MADD domain containing 1A |
| DENND4A | DENN/MADD domain containing 4A |
| DNAJC12 | DnaJ (Hsp40) homolog, subfamily C, member 12 |
| DNAJC24 | DnaJ (Hsp40) homolog, subfamily C, member 24 |
| DRAP1 | DR1-associated protein 1 (negative cofactor 2 alpha) |
| DUSP12 | dual specificity phosphatase 12 |
| ERCC2 | excision repair cross-complementation group 2 |
| ERCC5 | excision repair cross-complementation group 5 |
| FAM160B2 | family with sequence similarity 160, member B2 |
| GAR1 | GAR1 ribonucleoprotein |
| GBAS | glioblastoma amplified sequence |
| GNG3 | guanine nucleotide binding protein (G protein), gamma 3 |
| GSTM3 | glutathione S-transferase mu 3 (brain) |
| HACD2 | 3-hydroxyacyl-CoA dehydratase 2 |
| HMGB3P1 | high mobility group box 3 pseudogene 1 |
| HSPA14 | heat shock 70kDa protein 14 |
| HSPBP1 | HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1 |
| HYOU1 | hypoxia up-regulated 1 |
| IFI30 | interferon, gamma-inducible protein 30 |
| ITGAV | integrin, alpha V |
| JMJD4 | jumonji domain containing 4 |
| KCNK5 | potassium channel, two pore domain subfamily K, member 5 |
| KIAA0753 | KIAA0753 |
| KIAA0922 | KIAA0922 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) |
| LAMP5 | lysosomal-associated membrane protein family, member 5 |
| LAMTOR2 | late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 |
| LOC642236 | FSHD region gene 1 pseudogene |
| MCAT | malonyl CoA:ACP acyltransferase (mitochondrial) |
| METTL18 | methyltransferase like 18 |
| MLST8 | MTOR associated protein, LST8 homolog (S. cerevisiae) |
| MTERF3 | mitochondrial transcription termination factor 3 |
| NAGPA | N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase |
| NDST2 | N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2 |
| NDUFB6 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa |
| NFS1 | NFS1 cysteine desulfurase |
| PSMD3 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 |
| PUS1 | pseudouridylate synthase 1 |
| QDPR | quinoid dihydropteridine reductase |
| RAB21 | RAB21, member RAS oncogene family |
| RAB5C | RAB5C, member RAS oncogene family |
| RAP1A | RAP1A, member of RAS oncogene family |
| REXO4 | REX4, RNA exonuclease 4 homolog (S. cerevisiae) |
| RFK | riboflavin kinase |
| RHOF | ras homolog family member F (in filopodia) |
| RNF139 | ring finger protein 139 |
| RNF146 | ring finger protein 146 |
| RPS14P3 | ribosomal protein S14 pseudogene 3 |
| RRP9 | ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast) |
| SAC3D1 | SAC3 domain containing 1 |
| SASH3 | SAM and SH3 domain containing 3 |
| SDHAF3 | succinate dehydrogenase complex assembly factor 3 |
| SEC61B | Sec61 beta subunit |
| SLC35C2 | solute carrier family 35 (GDP-fucose transporter), member C2 |
| SNRNP40 | small nuclear ribonucleoprotein 40kDa (U5) |
| SPX | spexin hormone |
| SREBF1 | sterol regulatory element binding transcription factor 1 |
| STEAP3 | STEAP family member 3, metalloreductase |
| TAF2 | TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa |
| TM2D3 | TM2 domain containing 3 |
| TM7SF3 | transmembrane 7 superfamily member 3 |
| TMEM110 | transmembrane protein 110 |
| TMEM208 | transmembrane protein 208 |
| TNFRSF12A | tumor necrosis factor receptor superfamily, member 12A |
| TPX2 | TPX2, microtubule-associated |
| TUBA3D | tubulin, alpha 3d |
| TXNDC15 | thioredoxin domain containing 15 |
| UROS | uroporphyrinogen III synthase |
| USP5 | ubiquitin specific peptidase 5 (isopeptidase T) |
| WWC2 | WW and C2 domain containing 2 |
| ZNF106 | zinc finger protein 106 |
| ZNF273 | zinc finger protein 273 |
| ZNF669 | zinc finger protein 669 |
| ZNF84 | zinc finger protein 84 |
| ZW10 | zw10 kinetochore protein |
