ketanserin-3209 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
Similar Terms
Downloads & Tools

Genes

196 genes differentially expressed following the ketanserin-3209 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ADD2 adducin 2 (beta)
ADTRP androgen-dependent TFPI-regulating protein
ANPEP alanyl (membrane) aminopeptidase
ATP10B ATPase, class V, type 10B
ATP2B2 ATPase, Ca++ transporting, plasma membrane 2
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
AUTS2 autism susceptibility candidate 2
BAG4 BCL2-associated athanogene 4
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
C19ORF66 chromosome 19 open reading frame 66
CALML3 calmodulin-like 3
CASP10 caspase 10, apoptosis-related cysteine peptidase
CCL2 chemokine (C-C motif) ligand 2
CCL27 chemokine (C-C motif) ligand 27
CCR7 chemokine (C-C motif) receptor 7
CDH8 cadherin 8, type 2
CDK13 cyclin-dependent kinase 13
CDK6 cyclin-dependent kinase 6
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CEL carboxyl ester lipase
CEP112 centrosomal protein 112kDa
CPQ carboxypeptidase Q
CRHR2 corticotropin releasing hormone receptor 2
CSHL1 chorionic somatomammotropin hormone-like 1
CUL7 cullin 7
CXCL8 chemokine (C-X-C motif) ligand 8
DMP1 dentin matrix acidic phosphoprotein 1
DTNB dystrobrevin, beta
DUSP6 dual specificity phosphatase 6
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1
EPAS1 endothelial PAS domain protein 1
ERC2-IT1 ERC2 intronic transcript 1
EXO5 exonuclease 5
FABP7 fatty acid binding protein 7, brain
FAM65A family with sequence similarity 65, member A
FBXL8 F-box and leucine-rich repeat protein 8
FLJ11292
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GRM1 glutamate receptor, metabotropic 1
HIST1H3E histone cluster 1, H3e
HOXA4 homeobox A4
IFNA14 interferon, alpha 14
IFT27 intraflagellar transport 27
IGL immunoglobulin lambda locus
KCNQ2 potassium channel, voltage gated KQT-like subfamily Q, member 2
KCTD17 potassium channel tetramerization domain containing 17
KIF13A kinesin family member 13A
KLF1 Kruppel-like factor 1 (erythroid)
KRT17 keratin 17, type I
KRT8 keratin 8, type II
LAT2 linker for activation of T cells family, member 2
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LLPH LLP homolog, long-term synaptic facilitation (Aplysia)
LOC257152 uncharacterized LOC257152
LRCH4 leucine-rich repeats and calponin homology (CH) domain containing 4
LY6G6C lymphocyte antigen 6 complex, locus G6C
MCAM melanoma cell adhesion molecule
MGAM maltase-glucoamylase
MYRF myelin regulatory factor
NAALAD2 N-acetylated alpha-linked acidic dipeptidase 2
NEUROD4 neuronal differentiation 4
NF1 neurofibromin 1
NOVA2 neuro-oncological ventral antigen 2
NYNRIN NYN domain and retroviral integrase containing
PARVA parvin, alpha
PBOV1 prostate and breast cancer overexpressed 1
PRAMEF11 PRAME family member 11
PROL1 proline rich, lacrimal 1
RBFA ribosome binding factor A (putative)
RGS12 regulator of G-protein signaling 12
S100A9 S100 calcium binding protein A9
SAMD4A sterile alpha motif domain containing 4A
SIX3 SIX homeobox 3
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4
SLC22A7 solute carrier family 22 (organic anion transporter), member 7
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
STEAP4 STEAP family member 4
SYNPO synaptopodin
TAF9B TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa
TFR2 transferrin receptor 2
TIMM8A translocase of inner mitochondrial membrane 8 homolog A (yeast)
TLE2 transducin-like enhancer of split 2
TLK1 tousled-like kinase 1
TNK2 tyrosine kinase, non-receptor, 2
TRD T cell receptor delta locus
TRIM31 tripartite motif containing 31
TTC38 tetratricopeptide repeat domain 38
UGT2B15 UDP glucuronosyltransferase 2 family, polypeptide B15
UNC93A unc-93 homolog A (C. elegans)
UPF3A UPF3 regulator of nonsense transcripts homolog A (yeast)
URB1 URB1 ribosome biogenesis 1 homolog (S. cerevisiae)
UROD uroporphyrinogen decarboxylase
WIZ widely interspaced zinc finger motifs
ZNF747 zinc finger protein 747
ZNF783 zinc finger family member 783

decreased expression

Symbol Name
APLP1 amyloid beta (A4) precursor-like protein 1
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
BRIP1 BRCA1 interacting protein C-terminal helicase 1
BTF3P12 basic transcription factor 3 pseudogene 12
C10ORF95 chromosome 10 open reading frame 95
C17ORF80 chromosome 17 open reading frame 80
C19ORF40 chromosome 19 open reading frame 40
C1ORF159 chromosome 1 open reading frame 159
C8ORF60 chromosome 8 open reading frame 60
CA5BP1 carbonic anhydrase VB pseudogene 1
CAPN5 calpain 5
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CEMIP cell migration inducing protein, hyaluronan binding
CHKB choline kinase beta
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
CIR1 corepressor interacting with RBPJ, 1
CLCN5 chloride channel, voltage-sensitive 5
CNGB3 cyclic nucleotide gated channel beta 3
CNR2 cannabinoid receptor 2 (macrophage)
COMMD10 COMM domain containing 10
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
DCAF17 DDB1 and CUL4 associated factor 17
DEPTOR DEP domain containing MTOR-interacting protein
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
DYSF dysferlin
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
FBXO22 F-box protein 22
FOXN2 forkhead box N2
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2
GDAP1 ganglioside induced differentiation associated protein 1
GIF gastric intrinsic factor (vitamin B synthesis)
GNA13 guanine nucleotide binding protein (G protein), alpha 13
HIST1H1C histone cluster 1, H1c
HIST1H2AI histone cluster 1, H2ai
HIST1H2AL histone cluster 1, H2al
HIST1H4F histone cluster 1, H4f
HOXD11 homeobox D11
HYI hydroxypyruvate isomerase (putative)
IFT22 intraflagellar transport 22
IL15RA interleukin 15 receptor, alpha
IQSEC2 IQ motif and Sec7 domain 2
IRF6 interferon regulatory factor 6
KIAA0754 KIAA0754
KITLG KIT ligand
LRP2 low density lipoprotein receptor-related protein 2
LYZ lysozyme
LZTFL1 leucine zipper transcription factor-like 1
LZTS3 leucine zipper, putative tumor suppressor family member 3
MBTPS2 membrane-bound transcription factor peptidase, site 2
MGC12488
MOCS3 molybdenum cofactor synthesis 3
MT1H metallothionein 1H
MUC3A mucin 3A, cell surface associated
NFE2L3 nuclear factor, erythroid 2-like 3
NLGN1 neuroligin 1
NPM3 nucleophosmin/nucleoplasmin 3
NUS1P3 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) pseudogene 3
OLFML3 olfactomedin-like 3
PCDHA6 protocadherin alpha 6
PGGT1B protein geranylgeranyltransferase type I, beta subunit
PLAC8 placenta-specific 8
POM121 POM121 transmembrane nucleoporin
POTEKP POTE ankyrin domain family, member K, pseudogene
PRKAB2 protein kinase, AMP-activated, beta 2 non-catalytic subunit
R3HCC1L R3H domain and coiled-coil containing 1-like
RAB23 RAB23, member RAS oncogene family
RAB3A RAB3A, member RAS oncogene family
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RAB5C RAB5C, member RAS oncogene family
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RNF122 ring finger protein 122
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
SCGB2A2 secretoglobin, family 2A, member 2
SCYL2 SCY1-like 2 (S. cerevisiae)
SETD8 SET domain containing (lysine methyltransferase) 8
SLC12A6 solute carrier family 12 (potassium/chloride transporter), member 6
SLC25A40 solute carrier family 25, member 40
STAB2 stabilin 2
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae)
SYNC syncoilin, intermediate filament protein
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TCTA T-cell leukemia translocation altered
TMEM230 transmembrane protein 230
TRIM25 tripartite motif containing 25
TUBA3C tubulin, alpha 3c
TUBGCP5 tubulin, gamma complex associated protein 5
USP18 ubiquitin specific peptidase 18
VGF VGF nerve growth factor inducible
YIPF5 Yip1 domain family, member 5
ZBTB22 zinc finger and BTB domain containing 22
ZNF141 zinc finger protein 141
ZNF205 zinc finger protein 205
ZNF227 zinc finger protein 227
ZNF273 zinc finger protein 273
ZNF665 zinc finger protein 665