| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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192 genes differentially expressed following the ketanserin-6649 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| A4GALT | alpha 1,4-galactosyltransferase |
| ACE | angiotensin I converting enzyme |
| ACHE | acetylcholinesterase (Yt blood group) |
| ADAM22 | ADAM metallopeptidase domain 22 |
| ADGRG1 | adhesion G protein-coupled receptor G1 |
| ADRA1A | adrenoceptor alpha 1A |
| ADRB1 | adrenoceptor beta 1 |
| ALDOB | aldolase B, fructose-bisphosphate |
| AMPH | amphiphysin |
| ANGEL2 | angel homolog 2 (Drosophila) |
| ARVCF | armadillo repeat gene deleted in velocardiofacial syndrome |
| ATXN3L | ataxin 3-like |
| BAIAP3 | BAI1-associated protein 3 |
| BCL11B | B-cell CLL/lymphoma 11B (zinc finger protein) |
| BEGAIN | brain-enriched guanylate kinase-associated |
| C3AR1 | complement component 3a receptor 1 |
| CA1 | carbonic anhydrase I |
| CADM4 | cell adhesion molecule 4 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase |
| CEACAM3 | carcinoembryonic antigen-related cell adhesion molecule 3 |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha |
| CLCN6 | chloride channel, voltage-sensitive 6 |
| CLEC4A | C-type lectin domain family 4, member A |
| CLMN | calmin (calponin-like, transmembrane) |
| CTNS | cystinosin, lysosomal cystine transporter |
| DCC | DCC netrin 1 receptor |
| DDC | dopa decarboxylase (aromatic L-amino acid decarboxylase) |
| DIAPH2-AS1 | DIAPH2 antisense RNA 1 |
| DMRT1 | doublesex and mab-3 related transcription factor 1 |
| ENPEP | glutamyl aminopeptidase (aminopeptidase A) |
| FGF6 | fibroblast growth factor 6 |
| FXYD2 | FXYD domain containing ion transport regulator 2 |
| FZD10 | frizzled class receptor 10 |
| GIP | gastric inhibitory polypeptide |
| HGD | homogentisate 1,2-dioxygenase |
| HGF | hepatocyte growth factor (hepapoietin A; scatter factor) |
| HLA-DRB1 | major histocompatibility complex, class II, DR beta 1 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M |
| IL37 | interleukin 37 |
| INCENP | inner centromere protein antigens 135/155kDa |
| INHBC | inhibin, beta C |
| KCND3 | potassium channel, voltage gated Shal related subfamily D, member 3 |
| KCNJ5 | potassium channel, inwardly rectifying subfamily J, member 5 |
| KIAA1024 | KIAA1024 |
| LOC100129648 | uncharacterized LOC100129648 |
| LPL | lipoprotein lipase |
| MEP1B | meprin A, beta |
| MERTK | MER proto-oncogene, tyrosine kinase |
| MGAT3 | mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase |
| MGC2889 | uncharacterized protein MGC2889 |
| MGEA5 | meningioma expressed antigen 5 (hyaluronidase) |
| MYH7 | myosin, heavy chain 7, cardiac muscle, beta |
| MYOZ3 | myozenin 3 |
| NDOR1 | NADPH dependent diflavin oxidoreductase 1 |
| NOVA2 | neuro-oncological ventral antigen 2 |
| NPPB | natriuretic peptide B |
| NR1I3 | nuclear receptor subfamily 1, group I, member 3 |
| NRCAM | neuronal cell adhesion molecule |
| NTNG1 | netrin G1 |
| OBSCN | obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF |
| OR10H3 | olfactory receptor, family 10, subfamily H, member 3 |
| PAOX | polyamine oxidase (exo-N4-amino) |
| PCDHB3 | protocadherin beta 3 |
| PCNX | pecanex homolog (Drosophila) |
| PDE11A | phosphodiesterase 11A |
| PDE4C | phosphodiesterase 4C, cAMP-specific |
| PDE5A | phosphodiesterase 5A, cGMP-specific |
| PGAP3 | post-GPI attachment to proteins 3 |
| PLA2R1 | phospholipase A2 receptor 1, 180kDa |
| PON3 | paraoxonase 3 |
| PRODH2 | proline dehydrogenase (oxidase) 2 |
| PROZ | protein Z, vitamin K-dependent plasma glycoprotein |
| PRSS12 | protease, serine, 12 (neurotrypsin, motopsin) |
| PSG4 | pregnancy specific beta-1-glycoprotein 4 |
| RASSF4 | Ras association (RalGDS/AF-6) domain family member 4 |
| RIMS3 | regulating synaptic membrane exocytosis 3 |
| RIN3 | Ras and Rab interactor 3 |
| RPL10 | ribosomal protein L10 |
| RYR1 | ryanodine receptor 1 (skeletal) |
| SCN5A | sodium channel, voltage gated, type V alpha subunit |
| SEMA3F | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F |
| SEMA3G | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 |
| SLC34A2 | solute carrier family 34 (type II sodium/phosphate cotransporter), member 2 |
| SLCO1B1 | solute carrier organic anion transporter family, member 1B1 |
| SNX13 | sorting nexin 13 |
| SP110 | SP110 nuclear body protein |
| SPRR3 | small proline-rich protein 3 |
| SRGAP3 | SLIT-ROBO Rho GTPase activating protein 3 |
| SSTR4 | somatostatin receptor 4 |
| TJP3 | tight junction protein 3 |
| TLK1 | tousled-like kinase 1 |
| TPM1 | tropomyosin 1 (alpha) |
| TRPC4 | transient receptor potential cation channel, subfamily C, member 4 |
| TTLL3 | tubulin tyrosine ligase-like family member 3 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 |
| ZNF334 | zinc finger protein 334 |
| Symbol | Name |
|---|---|
| ACADS | acyl-CoA dehydrogenase, C-2 to C-3 short chain |
| ACVR2B | activin A receptor, type IIB |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 |
| ALPK1 | alpha-kinase 1 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 |
| ASAP1-IT1 | ASAP1 intronic transcript 1 |
| ATAD5 | ATPase family, AAA domain containing 5 |
| ATG16L1 | autophagy related 16-like 1 (S. cerevisiae) |
| ATP13A2 | ATPase type 13A2 |
| ATPAF2 | ATP synthase mitochondrial F1 complex assembly factor 2 |
| BNC2 | basonuclin 2 |
| BRPF1 | bromodomain and PHD finger containing, 1 |
| C19ORF40 | chromosome 19 open reading frame 40 |
| C1ORF159 | chromosome 1 open reading frame 159 |
| C1QTNF1 | C1q and tumor necrosis factor related protein 1 |
| C5ORF42 | chromosome 5 open reading frame 42 |
| CAPN15 | calpain 15 |
| CASZ1 | castor zinc finger 1 |
| CCNT1 | cyclin T1 |
| CD82 | CD82 molecule |
| CDT1 | chromatin licensing and DNA replication factor 1 |
| COLGALT2 | collagen beta(1-O)galactosyltransferase 2 |
| CPEB1 | cytoplasmic polyadenylation element binding protein 1 |
| DTX2 | deltex 2, E3 ubiquitin ligase |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 |
| FAM86C1 | family with sequence similarity 86, member C1 |
| FCGR2A | Fc fragment of IgG, low affinity IIa, receptor (CD32) |
| FKBP10 | FK506 binding protein 10, 65 kDa |
| FSTL3 | follistatin-like 3 (secreted glycoprotein) |
| FUZ | fuzzy planar cell polarity protein |
| GAS8 | growth arrest-specific 8 |
| H1F0 | H1 histone family, member 0 |
| HDAC7 | histone deacetylase 7 |
| HIST1H1E | histone cluster 1, H1e |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 |
| HLX | H2.0-like homeobox |
| HOXB5 | homeobox B5 |
| HSF2BP | heat shock transcription factor 2 binding protein |
| IFNA14 | interferon, alpha 14 |
| IL7R | interleukin 7 receptor |
| IQSEC2 | IQ motif and Sec7 domain 2 |
| KIFC1 | kinesin family member C1 |
| LMNB1 | lamin B1 |
| LOC202181 | SUMO-interacting motifs containing 1 pseudogene |
| LZTR1 | leucine-zipper-like transcription regulator 1 |
| MAP3K12 | mitogen-activated protein kinase kinase kinase 12 |
| MILR1 | mast cell immunoglobulin-like receptor 1 |
| MIS18BP1 | MIS18 binding protein 1 |
| MN1 | meningioma (disrupted in balanced translocation) 1 |
| MRPL52 | mitochondrial ribosomal protein L52 |
| MYL5 | myosin, light chain 5, regulatory |
| NME5 | NME/NM23 family member 5 |
| NR1D2 | nuclear receptor subfamily 1, group D, member 2 |
| NSMF | NMDA receptor synaptonuclear signaling and neuronal migration factor |
| OPA3 | optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) |
| PACSIN3 | protein kinase C and casein kinase substrate in neurons 3 |
| PDIA3 | protein disulfide isomerase family A, member 3 |
| PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
| PRR7 | proline rich 7 (synaptic) |
| PTCD2 | pentatricopeptide repeat domain 2 |
| RABL6 | RAB, member RAS oncogene family-like 6 |
| RAD54L2 | RAD54-like 2 (S. cerevisiae) |
| RAI2 | retinoic acid induced 2 |
| RNF31 | ring finger protein 31 |
| S100A3 | S100 calcium binding protein A3 |
| SCEL | sciellin |
| SCML2 | sex comb on midleg-like 2 (Drosophila) |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
| SEPP1 | selenoprotein P, plasma, 1 |
| SKI | SKI proto-oncogene |
| SLC39A1 | solute carrier family 39 (zinc transporter), member 1 |
| SLC9A2 | solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2 |
| SMAD5 | SMAD family member 5 |
| SOX12 | SRY (sex determining region Y)-box 12 |
| SPIN1 | spindlin 1 |
| SYNGR3 | synaptogyrin 3 |
| SYNPO | synaptopodin |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 |
| TAP1 | transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) |
| TARS2 | threonyl-tRNA synthetase 2, mitochondrial (putative) |
| TENM1 | teneurin transmembrane protein 1 |
| TEX40 | testis expressed 40 |
| TINAGL1 | tubulointerstitial nephritis antigen-like 1 |
| TMC5 | transmembrane channel-like 5 |
| TOR4A | torsin family 4, member A |
| TRIM25 | tripartite motif containing 25 |
| WDR25 | WD repeat domain 25 |
| XYLT2 | xylosyltransferase II |
| YEATS2 | YEATS domain containing 2 |
| YY2 | YY2 transcription factor |
| ZNF214 | zinc finger protein 214 |
| ZNF551 | zinc finger protein 551 |
| ZNF76 | zinc finger protein 76 |
| ZNF839 | zinc finger protein 839 |
