| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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195 genes differentially expressed following the ketoconazole-1285 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACACA | acetyl-CoA carboxylase alpha |
| ADCY3 | adenylate cyclase 3 |
| ADGRA3 | adhesion G protein-coupled receptor A3 |
| AEN | apoptosis enhancing nuclease |
| ARG2 | arginase 2 |
| ATF7IP | activating transcription factor 7 interacting protein |
| AURKA | aurora kinase A |
| BNIP1 | BCL2/adenovirus E1B 19kDa interacting protein 1 |
| C16ORF58 | chromosome 16 open reading frame 58 |
| CAPN10 | calpain 10 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase |
| COPS2 | COP9 signalosome subunit 2 |
| CREM | cAMP responsive element modulator |
| CRISPLD2 | cysteine-rich secretory protein LCCL domain containing 2 |
| DDX31 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 |
| DGCR11 | DiGeorge syndrome critical region gene 11 (non-protein coding) |
| DGCR8 | DGCR8 microprocessor complex subunit |
| DMTN | dematin actin binding protein |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 |
| DNAJC4 | DnaJ (Hsp40) homolog, subfamily C, member 4 |
| DOCK4 | dedicator of cytokinesis 4 |
| DRD2 | dopamine receptor D2 |
| EGR3 | early growth response 3 |
| ERLIN2 | ER lipid raft associated 2 |
| EXO5 | exonuclease 5 |
| FAM50B | family with sequence similarity 50, member B |
| FRY | furry homolog (Drosophila) |
| FST | follistatin |
| FTH1 | ferritin, heavy polypeptide 1 |
| G0S2 | G0/G1 switch 2 |
| GAB2 | GRB2-associated binding protein 2 |
| GCAT | glycine C-acetyltransferase |
| GK | glycerol kinase |
| GRIP2 | glutamate receptor interacting protein 2 |
| GRSF1 | G-rich RNA sequence binding factor 1 |
| HAAO | 3-hydroxyanthranilate 3,4-dioxygenase |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 |
| HIPK2 | homeodomain interacting protein kinase 2 |
| HIST1H1E | histone cluster 1, H1e |
| HTATIP2 | HIV-1 Tat interactive protein 2, 30kDa |
| IGHG1 | immunoglobulin heavy constant gamma 1 (G1m marker) |
| IL1RAP | interleukin 1 receptor accessory protein |
| IL24 | interleukin 24 |
| IL6ST | interleukin 6 signal transducer |
| INCENP | inner centromere protein antigens 135/155kDa |
| JAG1 | jagged 1 |
| KATNBL1 | katanin p80 subunit B-like 1 |
| KAZN | kazrin, periplakin interacting protein |
| KCNG1 | potassium channel, voltage gated modifier subfamily G, member 1 |
| KDM7A | lysine (K)-specific demethylase 7A |
| KYNU | kynureninase |
| MAP4 | microtubule-associated protein 4 |
| MARC2 | mitochondrial amidoxime reducing component 2 |
| MID1 | midline 1 |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) |
| NCBP1 | nuclear cap binding protein subunit 1, 80kDa |
| NEK3 | NIMA-related kinase 3 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| NRP1 | neuropilin 1 |
| NUMA1 | nuclear mitotic apparatus protein 1 |
| NUP160 | nucleoporin 160kDa |
| PCM1 | pericentriolar material 1 |
| PDE4B | phosphodiesterase 4B, cAMP-specific |
| PKNOX1 | PBX/knotted 1 homeobox 1 |
| PKP4 | plakophilin 4 |
| PLAGL2 | pleiomorphic adenoma gene-like 2 |
| PTGES2 | prostaglandin E synthase 2 |
| PVR | poliovirus receptor |
| RANBP1 | RAN binding protein 1 |
| RBFOX1 | RNA binding protein, fox-1 homolog (C. elegans) 1 |
| REPS1 | RALBP1 associated Eps domain containing 1 |
| RUFY3 | RUN and FYVE domain containing 3 |
| SENP3 | SUMO1/sentrin/SMT3 specific peptidase 3 |
| SENP6 | SUMO1/sentrin specific peptidase 6 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 |
| SNRPA1 | small nuclear ribonucleoprotein polypeptide A' |
| SOAT1 | sterol O-acyltransferase 1 |
| SPATA20 | spermatogenesis associated 20 |
| SRSF1 | serine/arginine-rich splicing factor 1 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) |
| SWAP70 | SWAP switching B-cell complex 70kDa subunit |
| TAF1C | TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa |
| TAOK1 | TAO kinase 1 |
| THBS1 | thrombospondin 1 |
| TM9SF4 | transmembrane 9 superfamily protein member 4 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 |
| TPD52L1 | tumor protein D52-like 1 |
| TRAM2 | translocation associated membrane protein 2 |
| TRMT12 | tRNA methyltransferase 12 homolog (S. cerevisiae) |
| UCP2 | uncoupling protein 2 (mitochondrial, proton carrier) |
| VAMP2 | vesicle-associated membrane protein 2 (synaptobrevin 2) |
| ZNF34 | zinc finger protein 34 |
| ZNF821 | zinc finger protein 821 |
| ZNHIT2 | zinc finger, HIT-type containing 2 |
| ZSCAN18 | zinc finger and SCAN domain containing 18 |
| Symbol | Name |
|---|---|
| ADM | adrenomedullin |
| ADRB2 | adrenoceptor beta 2, surface |
| AES | amino-terminal enhancer of split |
| ALDOC | aldolase C, fructose-bisphosphate |
| ARID3B | AT rich interactive domain 3B (BRIGHT-like) |
| BATF | basic leucine zipper transcription factor, ATF-like |
| BHLHE41 | basic helix-loop-helix family, member e41 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 |
| C1ORF21 | chromosome 1 open reading frame 21 |
| CCDC6 | coiled-coil domain containing 6 |
| CCDC88C | coiled-coil domain containing 88C |
| CD69 | CD69 molecule |
| CD82 | CD82 molecule |
| CHST12 | carbohydrate (chondroitin 4) sulfotransferase 12 |
| CLSPN | claspin |
| CORO7 | coronin 7 |
| CRYBB2P1 | crystallin, beta B2 pseudogene 1 |
| CTSD | cathepsin D |
| CX3CR1 | chemokine (C-X3-C motif) receptor 1 |
| CYTIP | cytohesin 1 interacting protein |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 |
| EGLN2 | egl-9 family hypoxia-inducible factor 2 |
| ENO2 | enolase 2 (gamma, neuronal) |
| F3 | coagulation factor III (thromboplastin, tissue factor) |
| FAM222B | family with sequence similarity 222, member B |
| FAM63A | family with sequence similarity 63, member A |
| FCGR2B | Fc fragment of IgG, low affinity IIb, receptor (CD32) |
| FILIP1L | filamin A interacting protein 1-like |
| GJA1 | gap junction protein, alpha 1, 43kDa |
| GLTSCR1 | glioma tumor suppressor candidate region gene 1 |
| GPHN | gephyrin |
| GPNMB | glycoprotein (transmembrane) nmb |
| GPRC5C | G protein-coupled receptor, class C, group 5, member C |
| HCAR3 | hydroxycarboxylic acid receptor 3 |
| HILPDA | hypoxia inducible lipid droplet-associated |
| HOPX | HOP homeobox |
| HPCAL1 | hippocalcin-like 1 |
| ITGB7 | integrin, beta 7 |
| JADE3 | jade family PHD finger 3 |
| KDM3A | lysine (K)-specific demethylase 3A |
| KDM5C | lysine (K)-specific demethylase 5C |
| KPTN | kaptin (actin binding protein) |
| LRRC42 | leucine rich repeat containing 42 |
| MINOS1P1 | mitochondrial inner membrane organizing system 1 pseudogene 1 |
| MPI | mannose phosphate isomerase |
| MTRF1 | mitochondrial translational release factor 1 |
| MXI1 | MAX interactor 1, dimerization protein |
| MYLIP | myosin regulatory light chain interacting protein |
| NCF1C | neutrophil cytosolic factor 1C pseudogene |
| NDRG1 | N-myc downstream regulated 1 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 |
| NMB | neuromedin B |
| NT5M | 5',3'-nucleotidase, mitochondrial |
| ORAI3 | ORAI calcium release-activated calcium modulator 3 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I |
| PAQR4 | progestin and adipoQ receptor family member IV |
| PDK1 | pyruvate dehydrogenase kinase, isozyme 1 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 |
| PLOD1 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 |
| PPFIA4 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 |
| RAB17 | RAB17, member RAS oncogene family |
| RAD54L2 | RAD54-like 2 (S. cerevisiae) |
| RCBTB2 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 |
| RGS13 | regulator of G-protein signaling 13 |
| RGS2 | regulator of G-protein signaling 2 |
| RNF121 | ring finger protein 121 |
| RNF122 | ring finger protein 122 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase |
| RNF2 | ring finger protein 2 |
| RRAGA | Ras-related GTP binding A |
| SCYL2 | SCY1-like 2 (S. cerevisiae) |
| SLC2A5 | solute carrier family 2 (facilitated glucose/fructose transporter), member 5 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 |
| SPP1 | secreted phosphoprotein 1 |
| STAG3 | stromal antigen 3 |
| STBD1 | starch binding domain 1 |
| TCTA | T-cell leukemia translocation altered |
| TGM5 | transglutaminase 5 |
| TM7SF2 | transmembrane 7 superfamily member 2 |
| TM7SF3 | transmembrane 7 superfamily member 3 |
| TMEM45A | transmembrane protein 45A |
| TNNT1 | troponin T type 1 (skeletal, slow) |
| TPBG | trophoblast glycoprotein |
| TRMU | tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase |
| TUBB6 | tubulin, beta 6 class V |
| UPB1 | ureidopropionase, beta |
| UPP1 | uridine phosphorylase 1 |
| VGLL4 | vestigial-like family member 4 |
| VPS11 | vacuolar protein sorting 11 homolog (S. cerevisiae) |
| YEATS2 | YEATS domain containing 2 |
| ZBED8 | zinc finger, BED-type containing 8 |
| ZHX2 | zinc fingers and homeoboxes 2 |
| ZNF395 | zinc finger protein 395 |
| ZNF623 | zinc finger protein 623 |
