| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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195 genes differentially expressed following the ketoconazole-2640 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AAGAB | alpha- and gamma-adaptin binding protein |
| ACAA2 | acetyl-CoA acyltransferase 2 |
| ADAM23 | ADAM metallopeptidase domain 23 |
| ADTRP | androgen-dependent TFPI-regulating protein |
| ANKRD53 | ankyrin repeat domain 53 |
| ASAP3 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 |
| ASPH | aspartate beta-hydroxylase |
| ATAT1 | alpha tubulin acetyltransferase 1 |
| ATF6B | activating transcription factor 6 beta |
| AUTS2 | autism susceptibility candidate 2 |
| B3GNT3 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 |
| BCL2 | B-cell CLL/lymphoma 2 |
| C11ORF16 | chromosome 11 open reading frame 16 |
| C14ORF79 | chromosome 14 open reading frame 79 |
| C3ORF18 | chromosome 3 open reading frame 18 |
| CA9 | carbonic anhydrase IX |
| CACNA1G | calcium channel, voltage-dependent, T type, alpha 1G subunit |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID |
| CD52 | CD52 molecule |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 |
| CEP162 | centrosomal protein 162kDa |
| CNPPD1 | cyclin Pas1/PHO80 domain containing 1 |
| CORO7 | coronin 7 |
| CPA4 | carboxypeptidase A4 |
| CUL7 | cullin 7 |
| DDN | dendrin |
| DGCR11 | DiGeorge syndrome critical region gene 11 (non-protein coding) |
| DIAPH2 | diaphanous-related formin 2 |
| DIO2 | deiodinase, iodothyronine, type II |
| DNAI2 | dynein, axonemal, intermediate chain 2 |
| DSTYK | dual serine/threonine and tyrosine protein kinase |
| DTNA | dystrobrevin, alpha |
| ELOVL2 | ELOVL fatty acid elongase 2 |
| ELOVL5 | ELOVL fatty acid elongase 5 |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 |
| EPHB6 | EPH receptor B6 |
| FGL1 | fibrinogen-like 1 |
| GIF | gastric intrinsic factor (vitamin B synthesis) |
| GTPBP4 | GTP binding protein 4 |
| HDAC7 | histone deacetylase 7 |
| HIST1H1T | histone cluster 1, H1t |
| HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 |
| HOXC5 | homeobox C5 |
| HOXC8 | homeobox C8 |
| IL33R | interleukin 33 receptor |
| IL6R | interleukin 6 receptor |
| INPP5J | inositol polyphosphate-5-phosphatase J |
| KCTD7 | potassium channel tetramerization domain containing 7 |
| KIAA0125 | KIAA0125 |
| KRT83 | keratin 83, type II |
| MINK1 | misshapen-like kinase 1 |
| MLLT4 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 |
| MMP16 | matrix metallopeptidase 16 (membrane-inserted) |
| MUC3B | mucin 3B, cell surface associated |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle |
| NACA2 | nascent polypeptide-associated complex alpha subunit 2 |
| NDUFA5 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 |
| NOS1 | nitric oxide synthase 1 (neuronal) |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
| NRP1 | neuropilin 1 |
| ONECUT2 | one cut homeobox 2 |
| PHOX2B | paired-like homeobox 2b |
| PIP | prolactin-induced protein |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| PPARD | peroxisome proliferator-activated receptor delta |
| PRB1 | proline-rich protein BstNI subfamily 1 |
| PRKCI | protein kinase C, iota |
| PROL1 | proline rich, lacrimal 1 |
| PSMD9 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 9 |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) |
| PTPRS | protein tyrosine phosphatase, receptor type, S |
| RABGAP1 | RAB GTPase activating protein 1 |
| RGS12 | regulator of G-protein signaling 12 |
| RHEB | Ras homolog enriched in brain |
| RPL35A | ribosomal protein L35a |
| RPS14 | ribosomal protein S14 |
| RPS6KA6 | ribosomal protein S6 kinase, 90kDa, polypeptide 6 |
| RS1 | retinoschisin 1 |
| SLC22A18AS | solute carrier family 22 (organic cation transporter), member 18 antisense |
| SMG6 | SMG6 nonsense mediated mRNA decay factor |
| SOS2 | son of sevenless homolog 2 (Drosophila) |
| SPDEF | SAM pointed domain containing ETS transcription factor |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 |
| STK11 | serine/threonine kinase 11 |
| SUGP1 | SURP and G patch domain containing 1 |
| TAOK1 | TAO kinase 1 |
| TCEB3B | transcription elongation factor B polypeptide 3B (elongin A2) |
| THBS3 | thrombospondin 3 |
| THBS4 | thrombospondin 4 |
| TMEM53 | transmembrane protein 53 |
| TTLL5 | tubulin tyrosine ligase-like family member 5 |
| UPK2 | uroplakin 2 |
| VCX2 | variable charge, X-linked 2 |
| VWA5A | von Willebrand factor A domain containing 5A |
| WSB1 | WD repeat and SOCS box containing 1 |
| YIPF4 | Yip1 domain family, member 4 |
| ZSCAN18 | zinc finger and SCAN domain containing 18 |
| Symbol | Name |
|---|---|
| ABHD14A | abhydrolase domain containing 14A |
| ACTR3B | ARP3 actin-related protein 3 homolog B (yeast) |
| AFAP1 | actin filament associated protein 1 |
| ARHGDIG | Rho GDP dissociation inhibitor (GDI) gamma |
| ARMC6 | armadillo repeat containing 6 |
| BAG4 | BCL2-associated athanogene 4 |
| C11ORF30 | chromosome 11 open reading frame 30 |
| C19ORF40 | chromosome 19 open reading frame 40 |
| C21ORF91 | chromosome 21 open reading frame 91 |
| CABYR | calcium binding tyrosine-(Y)-phosphorylation regulated |
| CD79B | CD79b molecule, immunoglobulin-associated beta |
| CDK3 | cyclin-dependent kinase 3 |
| CEP85 | centrosomal protein 85kDa |
| CEP97 | centrosomal protein 97kDa |
| CGA | glycoprotein hormones, alpha polypeptide |
| CHKB | choline kinase beta |
| CIDEC | cell death-inducing DFFA-like effector c |
| CLDND1 | claudin domain containing 1 |
| CNKSR1 | connector enhancer of kinase suppressor of Ras 1 |
| COL9A2 | collagen, type IX, alpha 2 |
| COX6A2 | cytochrome c oxidase subunit VIa polypeptide 2 |
| CRYBG3 | beta-gamma crystallin domain containing 3 |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DSCAM | Down syndrome cell adhesion molecule |
| DVL1 | dishevelled segment polarity protein 1 |
| EFNA3 | ephrin-A3 |
| EHMT1 | euchromatic histone-lysine N-methyltransferase 1 |
| ETAA1 | Ewing tumor-associated antigen 1 |
| EXD3 | exonuclease 3'-5' domain containing 3 |
| EXO5 | exonuclease 5 |
| F8 | coagulation factor VIII, procoagulant component |
| FAM189A2 | family with sequence similarity 189, member A2 |
| FBXO46 | F-box protein 46 |
| GBP2 | guanylate binding protein 2, interferon-inducible |
| GNAZ | guanine nucleotide binding protein (G protein), alpha z polypeptide |
| GRB7 | growth factor receptor-bound protein 7 |
| GRPR | gastrin-releasing peptide receptor |
| GTPBP2 | GTP binding protein 2 |
| GUCY1B2 | guanylate cyclase 1, soluble, beta 2 (pseudogene) |
| HIST2H2AA3 | histone cluster 2, H2aa3 |
| HOOK1 | hook microtubule-tethering protein 1 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
| IL17RA | interleukin 17 receptor A |
| IPO8 | importin 8 |
| ITPKC | inositol-trisphosphate 3-kinase C |
| KIAA0754 | KIAA0754 |
| KIF13B | kinesin family member 13B |
| LAMB3 | laminin, beta 3 |
| LIG4 | ligase IV, DNA, ATP-dependent |
| LINS | lines homolog (Drosophila) |
| LOC390998 | ribosomal protein L10 pseudogene |
| LSM14B | LSM14B, SCD6 homolog B (S. cerevisiae) |
| LY6G6C | lymphocyte antigen 6 complex, locus G6C |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| METTL8 | methyltransferase like 8 |
| MICAL1 | microtubule associated monooxygenase, calponin and LIM domain containing 1 |
| MUC3A | mucin 3A, cell surface associated |
| NDE1 | nudE neurodevelopment protein 1 |
| NEO1 | neogenin 1 |
| NIPAL2 | NIPA-like domain containing 2 |
| NUDT18 | nudix (nucleoside diphosphate linked moiety X)-type motif 18 |
| PHEX | phosphate regulating endopeptidase homolog, X-linked |
| PIM1 | Pim-1 proto-oncogene, serine/threonine kinase |
| PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
| RIPK1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RNF39 | ring finger protein 39 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) |
| RPL13P5 | ribosomal protein L13 pseudogene 5 |
| RPS17P5 | ribosomal protein S17 pseudogene 5 |
| RPS6KA4 | ribosomal protein S6 kinase, 90kDa, polypeptide 4 |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 |
| SGK1 | serum/glucocorticoid regulated kinase 1 |
| SLC26A6 | solute carrier family 26 (anion exchanger), member 6 |
| SLC39A7 | solute carrier family 39 (zinc transporter), member 7 |
| SLC4A8 | solute carrier family 4, sodium bicarbonate cotransporter, member 8 |
| SMEK2 | SMEK homolog 2, suppressor of mek1 (Dictyostelium) |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
| STX1A | syntaxin 1A (brain) |
| SUSD6 | sushi domain containing 6 |
| SYCP2 | synaptonemal complex protein 2 |
| THRAP3 | thyroid hormone receptor associated protein 3 |
| TRIM25 | tripartite motif containing 25 |
| TSPYL2 | TSPY-like 2 |
| TTLL1 | tubulin tyrosine ligase-like family member 1 |
| TUT1 | terminal uridylyl transferase 1, U6 snRNA-specific |
| TWF2 | twinfilin actin binding protein 2 |
| UNC119 | unc-119 homolog (C. elegans) |
| USB1 | U6 snRNA biogenesis 1 |
| VAV1 | vav 1 guanine nucleotide exchange factor |
| XYLT2 | xylosyltransferase II |
| ZC3H3 | zinc finger CCCH-type containing 3 |
| ZNF253 | zinc finger protein 253 |
| ZNF446 | zinc finger protein 446 |
| ZNF668 | zinc finger protein 668 |
| ZNF675 | zinc finger protein 675 |
| ZNF770 | zinc finger protein 770 |
