| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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191 genes differentially expressed following the ketoconazole-4624 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACADS | acyl-CoA dehydrogenase, C-2 to C-3 short chain |
| ADAM11 | ADAM metallopeptidase domain 11 |
| AGAP2 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 |
| ALPPL2 | alkaline phosphatase, placental-like 2 |
| ARHGAP28 | Rho GTPase activating protein 28 |
| BMP2 | bone morphogenetic protein 2 |
| C1ORF116 | chromosome 1 open reading frame 116 |
| C2CD2L | C2CD2-like |
| C5AR2 | complement component 5a receptor 2 |
| C5ORF42 | chromosome 5 open reading frame 42 |
| C6ORF10 | chromosome 6 open reading frame 10 |
| CA4 | carbonic anhydrase IV |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase |
| CCNG2 | cyclin G2 |
| CD1C | CD1c molecule |
| CD58 | CD58 molecule |
| CDC25C | cell division cycle 25C |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) |
| CES3 | carboxylesterase 3 |
| CHRNA3 | cholinergic receptor, nicotinic, alpha 3 (neuronal) |
| CHRNB3 | cholinergic receptor, nicotinic, beta 3 (neuronal) |
| CLCN6 | chloride channel, voltage-sensitive 6 |
| CLMN | calmin (calponin-like, transmembrane) |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 |
| CXCR6 | chemokine (C-X-C motif) receptor 6 |
| DDX11 | DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 |
| E2F4 | E2F transcription factor 4, p107/p130-binding |
| EBI3 | Epstein-Barr virus induced 3 |
| EFNA3 | ephrin-A3 |
| FBXO41 | F-box protein 41 |
| FLJ11292 | |
| FLT3LG | fms-related tyrosine kinase 3 ligand |
| GDAP1 | ganglioside induced differentiation associated protein 1 |
| GHRH | growth hormone releasing hormone |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
| GNL3LP1 | guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1 |
| GYG2 | glycogenin 2 |
| HHAT | hedgehog acyltransferase |
| HIC2 | hypermethylated in cancer 2 |
| HIST1H3F | histone cluster 1, H3f |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) |
| HOXC4 | homeobox C4 |
| HPSE2 | heparanase 2 (inactive) |
| HSF1 | heat shock transcription factor 1 |
| IL11 | interleukin 11 |
| IL6 | interleukin 6 |
| INSIG1 | insulin induced gene 1 |
| IRAK3 | interleukin-1 receptor-associated kinase 3 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) |
| KCNC1 | potassium channel, voltage gated Shaw related subfamily C, member 1 |
| KIAA1045 | KIAA1045 |
| KIR2DL5A | killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A |
| KLHL22 | kelch-like family member 22 |
| KSR1 | kinase suppressor of ras 1 |
| LARP4B | La ribonucleoprotein domain family, member 4B |
| LCAT | lecithin-cholesterol acyltransferase |
| LDLR | low density lipoprotein receptor |
| LINC00115 | long intergenic non-protein coding RNA 115 |
| LIPG | lipase, endothelial |
| LOC100287387 | uncharacterized LOC100287387 |
| LTBP4 | latent transforming growth factor beta binding protein 4 |
| LY9 | lymphocyte antigen 9 |
| LYPD3 | LY6/PLAUR domain containing 3 |
| MAP2K7 | mitogen-activated protein kinase kinase 7 |
| MAP3K13 | mitogen-activated protein kinase kinase kinase 13 |
| ME1 | malic enzyme 1, NADP(+)-dependent, cytosolic |
| MFAP5 | microfibrillar associated protein 5 |
| MTMR8 | myotubularin related protein 8 |
| MZF1 | myeloid zinc finger 1 |
| NTRK3 | neurotrophic tyrosine kinase, receptor, type 3 |
| OR12D3 | olfactory receptor, family 12, subfamily D, member 3 |
| OSGIN2 | oxidative stress induced growth inhibitor family member 2 |
| PACRG | PARK2 co-regulated |
| PDE4C | phosphodiesterase 4C, cAMP-specific |
| PDGFB | platelet-derived growth factor beta polypeptide |
| PHF20L1 | PHD finger protein 20-like 1 |
| PRUNE2 | prune homolog 2 (Drosophila) |
| S100A12 | S100 calcium binding protein A12 |
| SEMA7A | semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group) |
| SENP3 | SUMO1/sentrin/SMT3 specific peptidase 3 |
| SIDT2 | SID1 transmembrane family, member 2 |
| SKIL | SKI-like proto-oncogene |
| SLC7A8 | solute carrier family 7 (amino acid transporter light chain, L system), member 8 |
| SMAD6 | SMAD family member 6 |
| SPATA1 | spermatogenesis associated 1 |
| SPPL2B | signal peptide peptidase like 2B |
| TACR1 | tachykinin receptor 1 |
| TLE4 | transducin-like enhancer of split 4 |
| TMOD1 | tropomodulin 1 |
| TOP3A | topoisomerase (DNA) III alpha |
| TP53I11 | tumor protein p53 inducible protein 11 |
| TRAC | T cell receptor alpha constant |
| TSSK2 | testis-specific serine kinase 2 |
| TTC22 | tetratricopeptide repeat domain 22 |
| VCAN | versican |
| VPS16 | vacuolar protein sorting 16 homolog (S. cerevisiae) |
| VPS41 | vacuolar protein sorting 41 homolog (S. cerevisiae) |
| WT1 | Wilms tumor 1 |
| ZCCHC4 | zinc finger, CCHC domain containing 4 |
| ZFP2 | ZFP2 zinc finger protein |
| Symbol | Name |
|---|---|
| ABCG2 | ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) |
| ABHD17B | abhydrolase domain containing 17B |
| ACTR8 | ARP8 actin-related protein 8 homolog (yeast) |
| ADGRG2 | adhesion G protein-coupled receptor G2 |
| AGO4 | argonaute RISC catalytic component 4 |
| ALKBH4 | alkB, alkylation repair homolog 4 (E. coli) |
| ALOX12P2 | arachidonate 12-lipoxygenase pseudogene 2 |
| ALOX5AP | arachidonate 5-lipoxygenase-activating protein |
| ARHGAP24 | Rho GTPase activating protein 24 |
| B3GALT4 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4 |
| C19ORF40 | chromosome 19 open reading frame 40 |
| C9ORF91 | chromosome 9 open reading frame 91 |
| CARD8 | caspase recruitment domain family, member 8 |
| CCDC88C | coiled-coil domain containing 88C |
| CCT6B | chaperonin containing TCP1, subunit 6B (zeta 2) |
| CDADC1 | cytidine and dCMP deaminase domain containing 1 |
| CLCN5 | chloride channel, voltage-sensitive 5 |
| COMP | cartilage oligomeric matrix protein |
| CUTC | cutC copper transporter |
| DAGLA | diacylglycerol lipase, alpha |
| DDN | dendrin |
| DGCR9 | DiGeorge syndrome critical region gene 9 (non-protein coding) |
| DNAJC17 | DnaJ (Hsp40) homolog, subfamily C, member 17 |
| DNMBP | dynamin binding protein |
| ERMAP | erythroblast membrane-associated protein (Scianna blood group) |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FAM110B | family with sequence similarity 110, member B |
| FAT4 | FAT atypical cadherin 4 |
| FUT1 | fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) |
| GFOD1 | glucose-fructose oxidoreductase domain containing 1 |
| GSTA3 | glutathione S-transferase alpha 3 |
| GUCY1B2 | guanylate cyclase 1, soluble, beta 2 (pseudogene) |
| HDAC9 | histone deacetylase 9 |
| HIST1H2AK | histone cluster 1, H2ak |
| HIST1H2AM | histone cluster 1, H2am |
| HIST1H2BI | histone cluster 1, H2bi |
| HIST1H3C | histone cluster 1, H3c |
| HIST1H3I | histone cluster 1, H3i |
| HOOK1 | hook microtubule-tethering protein 1 |
| HSPB6 | heat shock protein, alpha-crystallin-related, B6 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 |
| IFT54 | intraflagellar transport 54 |
| IL1RAPL2 | interleukin 1 receptor accessory protein-like 2 |
| IL32 | interleukin 32 |
| IRF1 | interferon regulatory factor 1 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) |
| KRT33A | keratin 33A, type I |
| LRRC61 | leucine rich repeat containing 61 |
| MBTPS2 | membrane-bound transcription factor peptidase, site 2 |
| MRPL44 | mitochondrial ribosomal protein L44 |
| MXD3 | MAX dimerization protein 3 |
| NPM3 | nucleophosmin/nucleoplasmin 3 |
| NR1H4 | nuclear receptor subfamily 1, group H, member 4 |
| NRTN | neurturin |
| NUDT13 | nudix (nucleoside diphosphate linked moiety X)-type motif 13 |
| OLFM4 | olfactomedin 4 |
| OSBP2 | oxysterol binding protein 2 |
| PLAC8 | placenta-specific 8 |
| PLAG1 | pleiomorphic adenoma gene 1 |
| PLAT | plasminogen activator, tissue |
| POLH | polymerase (DNA directed), eta |
| PRICKLE3 | prickle homolog 3 (Drosophila) |
| PRM2 | protamine 2 |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RNF25 | ring finger protein 25 |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SCG5 | secretogranin V |
| SCGB2A2 | secretoglobin, family 2A, member 2 |
| SETD6 | SET domain containing 6 |
| SH3TC2 | SH3 domain and tetratricopeptide repeats 2 |
| SIX1 | SIX homeobox 1 |
| SLC25A28 | solute carrier family 25 (mitochondrial iron transporter), member 28 |
| SLC9A3 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 |
| SOBP | sine oculis binding protein homolog (Drosophila) |
| SRGAP2 | SLIT-ROBO Rho GTPase activating protein 2 |
| ST20 | suppressor of tumorigenicity 20 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa |
| TBC1D19 | TBC1 domain family, member 19 |
| TEX40 | testis expressed 40 |
| TINAGL1 | tubulointerstitial nephritis antigen-like 1 |
| TMEM132A | transmembrane protein 132A |
| TMEM2 | transmembrane protein 2 |
| TMEM242 | transmembrane protein 242 |
| TSPAN2 | tetraspanin 2 |
| USP5 | ubiquitin specific peptidase 5 (isopeptidase T) |
| WDR76 | WD repeat domain 76 |
| WDR91 | WD repeat domain 91 |
| YEATS4 | YEATS domain containing 4 |
| YY2 | YY2 transcription factor |
| ZNF442 | zinc finger protein 442 |
| ZNF702P | zinc finger protein 702, pseudogene |
