| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the ketoconazole-5685 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AAMDC | adipogenesis associated, Mth938 domain containing |
| ADAMTS7 | ADAM metallopeptidase with thrombospondin type 1 motif, 7 |
| ADORA1 | adenosine A1 receptor |
| AKAP8L | A kinase (PRKA) anchor protein 8-like |
| ALDOB | aldolase B, fructose-bisphosphate |
| ALPL | alkaline phosphatase, liver/bone/kidney |
| AMACR | alpha-methylacyl-CoA racemase |
| ASIC1 | acid sensing (proton gated) ion channel 1 |
| ATP10B | ATPase, class V, type 10B |
| ATP2B3 | ATPase, Ca++ transporting, plasma membrane 3 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding |
| B3GNTL1 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1 |
| BAZ1B | bromodomain adjacent to zinc finger domain, 1B |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A |
| BMP2 | bone morphogenetic protein 2 |
| C8A | complement component 8, alpha polypeptide |
| CCDC82 | coiled-coil domain containing 82 |
| CELF2 | CUGBP, Elav-like family member 2 |
| COL1A1 | collagen, type I, alpha 1 |
| CRP | C-reactive protein, pentraxin-related |
| CSF1 | colony stimulating factor 1 (macrophage) |
| CSN3 | casein kappa |
| CYP2C9 | cytochrome P450, family 2, subfamily C, polypeptide 9 |
| DKFZP434C153 | DKFZP434C153 protein |
| DNAH17 | dynein, axonemal, heavy chain 17 |
| DSG1 | desmoglein 1 |
| EPM2A | epilepsy, progressive myoclonus type 2A, Lafora disease (laforin) |
| EXOSC2 | exosome component 2 |
| F12 | coagulation factor XII (Hageman factor) |
| FCN1 | ficolin (collagen/fibrinogen domain containing) 1 |
| FGL1 | fibrinogen-like 1 |
| FRZB | frizzled-related protein |
| GABBR2 | gamma-aminobutyric acid (GABA) B receptor, 2 |
| HIPK2 | homeodomain interacting protein kinase 2 |
| HOXB2 | homeobox B2 |
| HOXB5 | homeobox B5 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) |
| HRH1 | histamine receptor H1 |
| ICOS | inducible T-cell co-stimulator |
| IL1B | interleukin 1, beta |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 |
| KLHL23 | kelch-like family member 23 |
| KLRF1 | killer cell lectin-like receptor subfamily F, member 1 |
| KRTAP9-9 | keratin associated protein 9-9 |
| LAMA2 | laminin, alpha 2 |
| LCP2 | lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) |
| LOC79999 | uncharacterized LOC79999 |
| LPIN1 | lipin 1 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 |
| MC5R | melanocortin 5 receptor |
| MCAM | melanoma cell adhesion molecule |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase |
| MYH14 | myosin, heavy chain 14, non-muscle |
| MYL3 | myosin, light chain 3, alkali; ventricular, skeletal, slow |
| NECAB2 | N-terminal EF-hand calcium binding protein 2 |
| NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
| NXF2 | nuclear RNA export factor 2 |
| PCDHGA10 | protocadherin gamma subfamily A, 10 |
| PGLYRP1 | peptidoglycan recognition protein 1 |
| PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
| PLK3 | polo-like kinase 3 |
| PLSCR3 | phospholipid scramblase 3 |
| PNMAL1 | paraneoplastic Ma antigen family-like 1 |
| PPARD | peroxisome proliferator-activated receptor delta |
| PPP2CB | protein phosphatase 2, catalytic subunit, beta isozyme |
| PRDM12 | PR domain containing 12 |
| PRDM14 | PR domain containing 14 |
| PRKCB | protein kinase C, beta |
| PSG11 | pregnancy specific beta-1-glycoprotein 11 |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) |
| RGS1 | regulator of G-protein signaling 1 |
| RIMS2 | regulating synaptic membrane exocytosis 2 |
| RORC | RAR-related orphan receptor C |
| S100A1 | S100 calcium binding protein A1 |
| SFTPD | surfactant protein D |
| SIRPB1 | signal-regulatory protein beta 1 |
| SLC30A10 | solute carrier family 30, member 10 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 |
| SLCO4C1 | solute carrier organic anion transporter family, member 4C1 |
| SOX21 | SRY (sex determining region Y)-box 21 |
| SOX30 | SRY (sex determining region Y)-box 30 |
| SP100 | SP100 nuclear antigen |
| SPOCK3 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3 |
| SRSF5 | serine/arginine-rich splicing factor 5 |
| STS | steroid sulfatase (microsomal), isozyme S |
| SYN2 | synapsin II |
| TAL1 | T-cell acute lymphocytic leukemia 1 |
| TBC1D19 | TBC1 domain family, member 19 |
| TCF4 | transcription factor 4 |
| TECTA | tectorin alpha |
| TLX2 | T-cell leukemia homeobox 2 |
| TNXB | tenascin XB |
| TRD | T cell receptor delta locus |
| TRPV4 | transient receptor potential cation channel, subfamily V, member 4 |
| TSSK2 | testis-specific serine kinase 2 |
| TUBA4B | tubulin, alpha 4b |
| UTS2 | urotensin 2 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 |
| ZNF76 | zinc finger protein 76 |
| Symbol | Name |
|---|---|
| ABCC2 | ATP-binding cassette, sub-family C (CFTR/MRP), member 2 |
| ACAD10 | acyl-CoA dehydrogenase family, member 10 |
| ADGRG2 | adhesion G protein-coupled receptor G2 |
| APBB3 | amyloid beta (A4) precursor protein-binding, family B, member 3 |
| ARHGEF16 | Rho guanine nucleotide exchange factor (GEF) 16 |
| ARHGEF26 | Rho guanine nucleotide exchange factor (GEF) 26 |
| ARNT2 | aryl-hydrocarbon receptor nuclear translocator 2 |
| ASPSCR1 | alveolar soft part sarcoma chromosome region, candidate 1 |
| ATP13A2 | ATPase type 13A2 |
| BAG4 | BCL2-associated athanogene 4 |
| BAHCC1 | BAH domain and coiled-coil containing 1 |
| BAX | BCL2-associated X protein |
| BCL11B | B-cell CLL/lymphoma 11B (zinc finger protein) |
| BCORL1 | BCL6 corepressor-like 1 |
| BTF3P12 | basic transcription factor 3 pseudogene 12 |
| C1QTNF9B-AS1 | C1QTNF9B antisense RNA 1 |
| C2ORF68 | chromosome 2 open reading frame 68 |
| C4ORF29 | chromosome 4 open reading frame 29 |
| CA11 | carbonic anhydrase XI |
| CCDC85C | coiled-coil domain containing 85C |
| CCP110 | centriolar coiled coil protein 110kDa |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha |
| CFAP44 | cilia and flagella associated protein 44 |
| CGA | glycoprotein hormones, alpha polypeptide |
| CGREF1 | cell growth regulator with EF-hand domain 1 |
| CHKB | choline kinase beta |
| CRABP1 | cellular retinoic acid binding protein 1 |
| CTAGE9 | CTAGE family, member 9 |
| CXORF21 | chromosome X open reading frame 21 |
| DDX6 | DEAD (Asp-Glu-Ala-Asp) box helicase 6 |
| DEAF1 | DEAF1 transcription factor |
| DGAT1 | diacylglycerol O-acyltransferase 1 |
| DGKD | diacylglycerol kinase, delta 130kDa |
| DUSP2 | dual specificity phosphatase 2 |
| DUSP8 | dual specificity phosphatase 8 |
| FCHO1 | FCH domain only 1 |
| FOXRED2 | FAD-dependent oxidoreductase domain containing 2 |
| FURIN | furin (paired basic amino acid cleaving enzyme) |
| GBP2 | guanylate binding protein 2, interferon-inducible |
| GINS4 | GINS complex subunit 4 (Sld5 homolog) |
| GTF2A1 | general transcription factor IIA, 1, 19/37kDa |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 |
| HGSNAT | heparan-alpha-glucosaminide N-acetyltransferase |
| HIRA | histone cell cycle regulator |
| KAT2A | K(lysine) acetyltransferase 2A |
| KCTD15 | potassium channel tetramerization domain containing 15 |
| KLK6 | kallikrein-related peptidase 6 |
| KRT8P12 | keratin 8 pseudogene 12 |
| LAIR2 | leukocyte-associated immunoglobulin-like receptor 2 |
| LRRC20 | leucine rich repeat containing 20 |
| LRRC37A3 | leucine rich repeat containing 37, member A3 |
| MAP9 | microtubule-associated protein 9 |
| MBTD1 | mbt domain containing 1 |
| MUL1 | mitochondrial E3 ubiquitin protein ligase 1 |
| NT5DC3 | 5'-nucleotidase domain containing 3 |
| OGFRL1 | opioid growth factor receptor-like 1 |
| OLFML2A | olfactomedin-like 2A |
| PC | pyruvate carboxylase |
| PDP1 | pyruvate dehyrogenase phosphatase catalytic subunit 1 |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| PIP5K1C | phosphatidylinositol-4-phosphate 5-kinase, type I, gamma |
| PITX2 | paired-like homeodomain 2 |
| PLEKHB1 | pleckstrin homology domain containing, family B (evectins) member 1 |
| POLE | polymerase (DNA directed), epsilon, catalytic subunit |
| PRSS16 | protease, serine, 16 (thymus) |
| PTPRU | protein tyrosine phosphatase, receptor type, U |
| REM1 | RAS (RAD and GEM)-like GTP-binding 1 |
| RIPK1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 |
| RPL13P5 | ribosomal protein L13 pseudogene 5 |
| S100A9 | S100 calcium binding protein A9 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 |
| SFMBT1 | Scm-like with four mbt domains 1 |
| SKA1 | spindle and kinetochore associated complex subunit 1 |
| SLC12A5 | solute carrier family 12 (potassium/chloride transporter), member 5 |
| SLC25A23 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 |
| SLC31A2 | solute carrier family 31 (copper transporter), member 2 |
| SLC46A3 | solute carrier family 46, member 3 |
| SLC4A8 | solute carrier family 4, sodium bicarbonate cotransporter, member 8 |
| SP140L | SP140 nuclear body protein-like |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) |
| SUV39H2 | suppressor of variegation 3-9 homolog 2 (Drosophila) |
| TBX19 | T-box 19 |
| TEP1 | telomerase-associated protein 1 |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TNKS2 | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 |
| TRAIP | TRAF interacting protein |
| TRMU | tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase |
| VPS39 | vacuolar protein sorting 39 homolog (S. cerevisiae) |
| VWA1 | von Willebrand factor A domain containing 1 |
| ZFHX3 | zinc finger homeobox 3 |
| ZNF141 | zinc finger protein 141 |
| ZNF250 | zinc finger protein 250 |
| ZNF324 | zinc finger protein 324 |
| ZNF408 | zinc finger protein 408 |
| ZNF652 | zinc finger protein 652 |
| ZNF787 | zinc finger protein 787 |
