| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the ketoprofen-3729 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AAGAB | alpha- and gamma-adaptin binding protein |
| ANP32A | acidic (leucine-rich) nuclear phosphoprotein 32 family, member A |
| AP1S1 | adaptor-related protein complex 1, sigma 1 subunit |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit |
| APLP2 | amyloid beta (A4) precursor-like protein 2 |
| APP | amyloid beta (A4) precursor protein |
| ATF6B | activating transcription factor 6 beta |
| ATG10 | autophagy related 10 |
| ATG16L1 | autophagy related 16-like 1 (S. cerevisiae) |
| BBC3 | BCL2 binding component 3 |
| BEGAIN | brain-enriched guanylate kinase-associated |
| BMP8B | bone morphogenetic protein 8b |
| BUB1 | BUB1 mitotic checkpoint serine/threonine kinase |
| C1QTNF9B-AS1 | C1QTNF9B antisense RNA 1 |
| C21ORF2 | chromosome 21 open reading frame 2 |
| CCDC186 | coiled-coil domain containing 186 |
| CCDC57 | coiled-coil domain containing 57 |
| CCL7 | chemokine (C-C motif) ligand 7 |
| CD47 | CD47 molecule |
| CEMP1 | cementum protein 1 |
| CLEC4E | C-type lectin domain family 4, member E |
| CNOT8 | CCR4-NOT transcription complex, subunit 8 |
| COL6A1 | collagen, type VI, alpha 1 |
| CPSF1 | cleavage and polyadenylation specific factor 1, 160kDa |
| CSF2 | colony stimulating factor 2 (granulocyte-macrophage) |
| CTSZ | cathepsin Z |
| CXCL12 | chemokine (C-X-C motif) ligand 12 |
| DACH1 | dachshund family transcription factor 1 |
| DLG4 | discs, large homolog 4 (Drosophila) |
| DNAJB5 | DnaJ (Hsp40) homolog, subfamily B, member 5 |
| DOK1 | docking protein 1, 62kDa (downstream of tyrosine kinase 1) |
| ENTPD1 | ectonucleoside triphosphate diphosphohydrolase 1 |
| EPHA5 | EPH receptor A5 |
| ETV5 | ets variant 5 |
| FBXO21 | F-box protein 21 |
| FKBP10 | FK506 binding protein 10, 65 kDa |
| GJA9 | gap junction protein, alpha 9, 59kDa |
| GOLGA6A | golgin A6 family, member A |
| GPLD1 | glycosylphosphatidylinositol specific phospholipase D1 |
| HIST1H3I | histone cluster 1, H3i |
| HTR1F | 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled |
| IGLJ3 | immunoglobulin lambda joining 3 |
| KAT6A | K(lysine) acetyltransferase 6A |
| KDM8 | lysine (K)-specific demethylase 8 |
| KIF21B | kinesin family member 21B |
| KRT24 | keratin 24, type I |
| LAMA4 | laminin, alpha 4 |
| LIMK1 | LIM domain kinase 1 |
| LRP1 | low density lipoprotein receptor-related protein 1 |
| LSM14B | LSM14B, SCD6 homolog B (S. cerevisiae) |
| MAPK8 | mitogen-activated protein kinase 8 |
| MARK2 | MAP/microtubule affinity-regulating kinase 2 |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) |
| MMP16 | matrix metallopeptidase 16 (membrane-inserted) |
| MMP3 | matrix metallopeptidase 3 |
| MNMIP1 | manchette microtubule inner protein 1 |
| MUC13 | mucin 13, cell surface associated |
| MVB12B | multivesicular body subunit 12B |
| NAALAD2 | N-acetylated alpha-linked acidic dipeptidase 2 |
| NCALD | neurocalcin delta |
| NFASC | neurofascin |
| NPM3 | nucleophosmin/nucleoplasmin 3 |
| OSGIN2 | oxidative stress induced growth inhibitor family member 2 |
| PBX2 | pre-B-cell leukemia homeobox 2 |
| PCDH11X | protocadherin 11 X-linked |
| PCDHB3 | protocadherin beta 3 |
| PDGFA | platelet-derived growth factor alpha polypeptide |
| PHOX2A | paired-like homeobox 2a |
| PLXND1 | plexin D1 |
| POU2F2 | POU class 2 homeobox 2 |
| POU3F2 | POU class 3 homeobox 2 |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha |
| PRAF2 | PRA1 domain family, member 2 |
| PVRL1 | poliovirus receptor-related 1 (herpesvirus entry mediator C) |
| RAB6A | RAB6A, member RAS oncogene family |
| RABEP2 | rabaptin, RAB GTPase binding effector protein 2 |
| RAC3 | ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) |
| RAD23B | RAD23 homolog B (S. cerevisiae) |
| RAD50 | RAD50 homolog (S. cerevisiae) |
| RBFOX1 | RNA binding protein, fox-1 homolog (C. elegans) 1 |
| REC8 | REC8 meiotic recombination protein |
| RGS4 | regulator of G-protein signaling 4 |
| SCN5A | sodium channel, voltage gated, type V alpha subunit |
| SLC16A5 | solute carrier family 16 (monocarboxylate transporter), member 5 |
| SLC35E2 | solute carrier family 35, member E2 |
| SLCO5A1 | solute carrier organic anion transporter family, member 5A1 |
| SRRT | serrate, RNA effector molecule |
| STAB2 | stabilin 2 |
| STK16 | serine/threonine kinase 16 |
| STRN3 | striatin, calmodulin binding protein 3 |
| SULT4A1 | sulfotransferase family 4A, member 1 |
| SYCE1L | synaptonemal complex central element protein 1-like |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa |
| TP63 | tumor protein p63 |
| TRAF4 | TNF receptor-associated factor 4 |
| VAC14 | Vac14 homolog (S. cerevisiae) |
| ZC3H7B | zinc finger CCCH-type containing 7B |
| ZNF287 | zinc finger protein 287 |
| Symbol | Name |
|---|---|
| ADAT1 | adenosine deaminase, tRNA-specific 1 |
| ADGRB2 | adhesion G protein-coupled receptor B2 |
| AIPL1 | aryl hydrocarbon receptor interacting protein-like 1 |
| AK5 | adenylate kinase 5 |
| ALPK1 | alpha-kinase 1 |
| ANKRD2 | ankyrin repeat domain 2 (stretch responsive muscle) |
| ANP32A-IT1 | ANP32A intronic transcript 1 |
| ARHGEF1 | Rho guanine nucleotide exchange factor (GEF) 1 |
| ARPIN | actin-related protein 2/3 complex inhibitor |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 |
| BCL11B | B-cell CLL/lymphoma 11B (zinc finger protein) |
| BMP4 | bone morphogenetic protein 4 |
| C1ORF105 | chromosome 1 open reading frame 105 |
| C1QTNF1 | C1q and tumor necrosis factor related protein 1 |
| C8ORF60 | chromosome 8 open reading frame 60 |
| CARHSP1 | calcium regulated heat stable protein 1, 24kDa |
| CCZ1B | CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae) |
| CDH19 | cadherin 19, type 2 |
| CINP | cyclin-dependent kinase 2 interacting protein |
| CYP2R1 | cytochrome P450, family 2, subfamily R, polypeptide 1 |
| DBF4B | DBF4 zinc finger B |
| DIP2A | DIP2 disco-interacting protein 2 homolog A (Drosophila) |
| DOK5 | docking protein 5 |
| ELP6 | elongator acetyltransferase complex subunit 6 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FADD | Fas (TNFRSF6)-associated via death domain |
| FBXL15 | F-box and leucine-rich repeat protein 15 |
| FBXW12 | F-box and WD repeat domain containing 12 |
| GBF1 | golgi brefeldin A resistant guanine nucleotide exchange factor 1 |
| GINS4 | GINS complex subunit 4 (Sld5 homolog) |
| GLB1L | galactosidase, beta 1-like |
| GMPR | guanosine monophosphate reductase |
| GPR1 | G protein-coupled receptor 1 |
| GRB7 | growth factor receptor-bound protein 7 |
| GRTP1 | growth hormone regulated TBC protein 1 |
| GTF2H3 | general transcription factor IIH, polypeptide 3, 34kDa |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| IFI44L | interferon-induced protein 44-like |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFNAR1 | interferon (alpha, beta and omega) receptor 1 |
| INE1 | inactivation escape 1 (non-protein coding) |
| KIAA0894 | KIAA0894 protein |
| KLHL36 | kelch-like family member 36 |
| KLRG1 | killer cell lectin-like receptor subfamily G, member 1 |
| LNPEP | leucyl/cystinyl aminopeptidase |
| LOC100286895 | cell division cycle 27 homolog pseudogene |
| LRRC37A3 | leucine rich repeat containing 37, member A3 |
| MCOLN3 | mucolipin 3 |
| MLC1 | megalencephalic leukoencephalopathy with subcortical cysts 1 |
| MPHOSPH8 | M-phase phosphoprotein 8 |
| NACAP1 | nascent-polypeptide-associated complex alpha polypeptide pseudogene 1 |
| NPFFR1 | neuropeptide FF receptor 1 |
| NPHP1 | nephronophthisis 1 (juvenile) |
| NSUN6 | NOP2/Sun domain family, member 6 |
| OLFML2A | olfactomedin-like 2A |
| OR12D2 | olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene) |
| PGPEP1 | pyroglutamyl-peptidase I |
| PHACTR4 | phosphatase and actin regulator 4 |
| PIGZ | phosphatidylinositol glycan anchor biosynthesis, class Z |
| PLEKHA2 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2 |
| PRF1 | perforin 1 (pore forming protein) |
| PRRG4 | proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 |
| RHBDD3 | rhomboid domain containing 3 |
| RNF125 | ring finger protein 125, E3 ubiquitin protein ligase |
| RPP25 | ribonuclease P/MRP 25kDa subunit |
| SDF2L1 | stromal cell-derived factor 2-like 1 |
| SH3BGR | SH3 domain binding glutamate-rich protein |
| SH3TC1 | SH3 domain and tetratricopeptide repeats 1 |
| SLC9A5 | solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5 |
| SNRPN | small nuclear ribonucleoprotein polypeptide N |
| STK19 | serine/threonine kinase 19 |
| STRN | striatin, calmodulin binding protein |
| SULT1B1 | sulfotransferase family, cytosolic, 1B, member 1 |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| TAOK1 | TAO kinase 1 |
| TBC1D2 | TBC1 domain family, member 2 |
| TEP1 | telomerase-associated protein 1 |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TIMP4 | TIMP metallopeptidase inhibitor 4 |
| TNFSF15 | tumor necrosis factor (ligand) superfamily, member 15 |
| TRIM16 | tripartite motif containing 16 |
| TRMT2B | tRNA methyltransferase 2 homolog B (S. cerevisiae) |
| TUT1 | terminal uridylyl transferase 1, U6 snRNA-specific |
| UBQLN4 | ubiquilin 4 |
| WDR4 | WD repeat domain 4 |
| XPNPEP3 | X-prolyl aminopeptidase 3, mitochondrial |
| XRCC2 | X-ray repair complementing defective repair in Chinese hamster cells 2 |
| ZNF160 | zinc finger protein 160 |
| ZNF264 | zinc finger protein 264 |
| ZNF282 | zinc finger protein 282 |
| ZNF286A | zinc finger protein 286A |
| ZNF426 | zinc finger protein 426 |
| ZNF480 | zinc finger protein 480 |
| ZNF611 | zinc finger protein 611 |
| ZNF652 | zinc finger protein 652 |
| ZNF665 | zinc finger protein 665 |
| ZNF721 | zinc finger protein 721 |
| ZNF74 | zinc finger protein 74 |
