| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the ketoprofen-4286 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AADAC | arylacetamide deacetylase |
| ADAM22 | ADAM metallopeptidase domain 22 |
| ADAM23 | ADAM metallopeptidase domain 23 |
| AGXT | alanine-glyoxylate aminotransferase |
| AKAP5 | A kinase (PRKA) anchor protein 5 |
| AMPD3 | adenosine monophosphate deaminase 3 |
| ARHGEF17 | Rho guanine nucleotide exchange factor (GEF) 17 |
| ARNT | aryl hydrocarbon receptor nuclear translocator |
| ATP11A | ATPase, class VI, type 11A |
| C22ORF46 | chromosome 22 open reading frame 46 |
| CBS | cystathionine-beta-synthase |
| CD6 | CD6 molecule |
| CD86 | CD86 molecule |
| CEP250 | centrosomal protein 250kDa |
| CHRNA3 | cholinergic receptor, nicotinic, alpha 3 (neuronal) |
| CHRNA6 | cholinergic receptor, nicotinic, alpha 6 (neuronal) |
| CIC | capicua transcriptional repressor |
| CITED1 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1 |
| CLDN17 | claudin 17 |
| CLDN8 | claudin 8 |
| COMT | catechol-O-methyltransferase |
| CSF1 | colony stimulating factor 1 (macrophage) |
| CSPG4 | chondroitin sulfate proteoglycan 4 |
| CTSG | cathepsin G |
| CYP2A7P1 | cytochrome P450, family 2, subfamily A, polypeptide 7 pseudogene 1 |
| CYP4F12 | cytochrome P450, family 4, subfamily F, polypeptide 12 |
| DDX51 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 51 |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| DST | dystonin |
| EFNB3 | ephrin-B3 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| ESR2 | estrogen receptor 2 (ER beta) |
| ESRRG | estrogen-related receptor gamma |
| FAM49B | family with sequence similarity 49, member B |
| FBXL18 | F-box and leucine-rich repeat protein 18 |
| FBXO4 | F-box protein 4 |
| FGF16 | fibroblast growth factor 16 |
| FGF18 | fibroblast growth factor 18 |
| GNRH2 | gonadotropin-releasing hormone 2 |
| GPNMB | glycoprotein (transmembrane) nmb |
| GPR17 | G protein-coupled receptor 17 |
| GREB1L | growth regulation by estrogen in breast cancer-like |
| GRIP2 | glutamate receptor interacting protein 2 |
| HS3ST3B1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1 |
| ICOS | inducible T-cell co-stimulator |
| INE1 | inactivation escape 1 (non-protein coding) |
| KCNF1 | potassium channel, voltage gated modifier subfamily F, member 1 |
| KCNQ3 | potassium channel, voltage gated KQT-like subfamily Q, member 3 |
| KCNS1 | potassium voltage-gated channel, modifier subfamily S, member 1 |
| KIAA0485 | uncharacterized LOC57235 |
| LDB2 | LIM domain binding 2 |
| LOC100287387 | uncharacterized LOC100287387 |
| MAP3K8 | mitogen-activated protein kinase kinase kinase 8 |
| MED25 | mediator complex subunit 25 |
| METTL7A | methyltransferase like 7A |
| MMP16 | matrix metallopeptidase 16 (membrane-inserted) |
| MOBP | myelin-associated oligodendrocyte basic protein |
| MSR1 | macrophage scavenger receptor 1 |
| MUC8 | mucin 8 |
| N4BP2L1 | NEDD4 binding protein 2-like 1 |
| NCR2 | natural cytotoxicity triggering receptor 2 |
| NEK9 | NIMA-related kinase 9 |
| NFASC | neurofascin |
| NOD2 | nucleotide-binding oligomerization domain containing 2 |
| NYNRIN | NYN domain and retroviral integrase containing |
| OR52A1 | olfactory receptor, family 52, subfamily A, member 1 |
| OSBPL7 | oxysterol binding protein-like 7 |
| PKP3 | plakophilin 3 |
| PLD1 | phospholipase D1, phosphatidylcholine-specific |
| PLK3 | polo-like kinase 3 |
| PRAF2 | PRA1 domain family, member 2 |
| PRODH2 | proline dehydrogenase (oxidase) 2 |
| PVT1 | Pvt1 oncogene (non-protein coding) |
| RECQL5 | RecQ protein-like 5 |
| RFPL2 | ret finger protein-like 2 |
| RGS5 | regulator of G-protein signaling 5 |
| RHEB | Ras homolog enriched in brain |
| RIMS2 | regulating synaptic membrane exocytosis 2 |
| RPH3A | rabphilin 3A |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 |
| RRP12 | ribosomal RNA processing 12 homolog (S. cerevisiae) |
| SEMA4F | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F |
| SH3BP2 | SH3-domain binding protein 2 |
| SIT1 | signaling threshold regulating transmembrane adaptor 1 |
| SLAMF7 | SLAM family member 7 |
| SLC16A4 | solute carrier family 16, member 4 |
| SLC30A5 | solute carrier family 30 (zinc transporter), member 5 |
| SLC9A2 | solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2 |
| SLC9A7 | solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7 |
| SLCO2A1 | solute carrier organic anion transporter family, member 2A1 |
| SMPX | small muscle protein, X-linked |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) |
| SYN3 | synapsin III |
| TBRG4 | transforming growth factor beta regulator 4 |
| UGT2B28 | UDP glucuronosyltransferase 2 family, polypeptide B28 |
| UPK2 | uroplakin 2 |
| VAMP1 | vesicle-associated membrane protein 1 (synaptobrevin 1) |
| ZC3H13 | zinc finger CCCH-type containing 13 |
| ZFP2 | ZFP2 zinc finger protein |
| ZNF549 | zinc finger protein 549 |
| Symbol | Name |
|---|---|
| APH1B | APH1B gamma secretase subunit |
| APOL6 | apolipoprotein L, 6 |
| ARID3B | AT rich interactive domain 3B (BRIGHT-like) |
| ARMCX2 | armadillo repeat containing, X-linked 2 |
| AXIN1 | axin 1 |
| BIRC3 | baculoviral IAP repeat containing 3 |
| C11ORF63 | chromosome 11 open reading frame 63 |
| C17ORF80 | chromosome 17 open reading frame 80 |
| C1ORF159 | chromosome 1 open reading frame 159 |
| C1QTNF1 | C1q and tumor necrosis factor related protein 1 |
| C1S | complement component 1, s subcomponent |
| C4ORF29 | chromosome 4 open reading frame 29 |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase |
| CBR4 | carbonyl reductase 4 |
| CCDC25 | coiled-coil domain containing 25 |
| CCDC71 | coiled-coil domain containing 71 |
| CCDC9 | coiled-coil domain containing 9 |
| CDK5RAP2 | CDK5 regulatory subunit associated protein 2 |
| CRMP1 | collapsin response mediator protein 1 |
| DECR2 | 2,4-dienoyl CoA reductase 2, peroxisomal |
| DLL3 | delta-like 3 (Drosophila) |
| DMBT1 | deleted in malignant brain tumors 1 |
| DNAAF2 | dynein, axonemal, assembly factor 2 |
| DTX4 | deltex 4, E3 ubiquitin ligase |
| DUSP9 | dual specificity phosphatase 9 |
| DZANK1 | double zinc ribbon and ankyrin repeat domains 1 |
| EGF | epidermal growth factor |
| EN1 | engrailed homeobox 1 |
| ENTPD5 | ectonucleoside triphosphate diphosphohydrolase 5 |
| ERCC2 | excision repair cross-complementation group 2 |
| ERCC4 | excision repair cross-complementation group 4 |
| EXD3 | exonuclease 3'-5' domain containing 3 |
| EYA4 | EYA transcriptional coactivator and phosphatase 4 |
| FKBP8 | FK506 binding protein 8, 38kDa |
| FOXN2 | forkhead box N2 |
| GALNT14 | polypeptide N-acetylgalactosaminyltransferase 14 |
| GBF1 | golgi brefeldin A resistant guanine nucleotide exchange factor 1 |
| GSK3A | glycogen synthase kinase 3 alpha |
| HDAC11 | histone deacetylase 11 |
| HIST1H4D | histone cluster 1, H4d |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 |
| HOXA2 | homeobox A2 |
| HYAL3 | hyaluronoglucosaminidase 3 |
| ITIH2 | inter-alpha-trypsin inhibitor heavy chain 2 |
| JUNB | jun B proto-oncogene |
| KDM4D | lysine (K)-specific demethylase 4D |
| KIAA0319L | KIAA0319-like |
| KLHL25 | kelch-like family member 25 |
| KRT75 | keratin 75, type II |
| LRP2 | low density lipoprotein receptor-related protein 2 |
| LRRC61 | leucine rich repeat containing 61 |
| MAGEA5 | melanoma antigen family A5 |
| MAPK12 | mitogen-activated protein kinase 12 |
| METTL22 | methyltransferase like 22 |
| MMP3 | matrix metallopeptidase 3 |
| MYL9 | myosin, light chain 9, regulatory |
| NABP2 | nucleic acid binding protein 2 |
| NME5 | NME/NM23 family member 5 |
| OSGIN1 | oxidative stress induced growth inhibitor 1 |
| PALM | paralemmin |
| PCOLCE | procollagen C-endopeptidase enhancer |
| PELP1 | proline, glutamate and leucine rich protein 1 |
| PIEZO1 | piezo-type mechanosensitive ion channel component 1 |
| PLCG2 | phospholipase C, gamma 2 (phosphatidylinositol-specific) |
| PLEKHO1 | pleckstrin homology domain containing, family O member 1 |
| PLXNB3 | plexin B3 |
| POLL | polymerase (DNA directed), lambda |
| POLR3D | polymerase (RNA) III (DNA directed) polypeptide D, 44kDa |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor |
| PRR15L | proline rich 15-like |
| PRR3 | proline rich 3 |
| PRR4 | proline rich 4 (lacrimal) |
| QTRT1 | queuine tRNA-ribosyltransferase 1 |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RAD9A | RAD9 homolog A (S. pombe) |
| RHOBTB2 | Rho-related BTB domain containing 2 |
| RNF31 | ring finger protein 31 |
| RRNAD1 | ribosomal RNA adenine dimethylase domain containing 1 |
| RUNX1-IT1 | RUNX1 intronic transcript 1 |
| SCAMP4 | secretory carrier membrane protein 4 |
| SLC25A21 | solute carrier family 25 (mitochondrial oxoadipate carrier), member 21 |
| SLC9A8 | solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8 |
| SMPD2 | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) |
| SSBP3 | single stranded DNA binding protein 3 |
| SUN2 | Sad1 and UNC84 domain containing 2 |
| SUV39H1 | suppressor of variegation 3-9 homolog 1 (Drosophila) |
| SYNGR3 | synaptogyrin 3 |
| TCEAL2 | transcription elongation factor A (SII)-like 2 |
| TEX40 | testis expressed 40 |
| TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) |
| TLN1 | talin 1 |
| TNRC6B | trinucleotide repeat containing 6B |
| VEGFB | vascular endothelial growth factor B |
| XAB2 | XPA binding protein 2 |
| ZNF254 | zinc finger protein 254 |
| ZNF358 | zinc finger protein 358 |
| ZNF778 | zinc finger protein 778 |
| ZYX | zyxin |
