ketoprofen-4751 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
Similar Terms
Downloads & Tools

Genes

199 genes differentially expressed following the ketoprofen-4751 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ACE2 angiotensin I converting enzyme 2
ADCK4 aarF domain containing kinase 4
AFF2 AF4/FMR2 family, member 2
AKT3 v-akt murine thymoma viral oncogene homolog 3
AMPD3 adenosine monophosphate deaminase 3
ASIC1 acid sensing (proton gated) ion channel 1
BCL2A1 BCL2-related protein A1
BCL2L10 BCL2-like 10 (apoptosis facilitator)
BST2 bone marrow stromal cell antigen 2
C11ORF21 chromosome 11 open reading frame 21
CADM3 cell adhesion molecule 3
CD58 CD58 molecule
CD70 CD70 molecule
CDH8 cadherin 8, type 2
CLCA2 chloride channel accessory 2
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CPA2 carboxypeptidase A2 (pancreatic)
CST4 cystatin S
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
CYTH4 cytohesin 4
EDN1 endothelin 1
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
EPN1 epsin 1
ERG v-ets avian erythroblastosis virus E26 oncogene homolog
EVA1B eva-1 homolog B (C. elegans)
FAM214B family with sequence similarity 214, member B
FBLN1 fibulin 1
FGF18 fibroblast growth factor 18
FGF22 fibroblast growth factor 22
FYB FYN binding protein
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
GJA8 gap junction protein, alpha 8, 50kDa
HCN2 hyperpolarization activated cyclic nucleotide gated potassium channel 2
HEMK1 HemK methyltransferase family member 1
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
HPX hemopexin
HS3ST3A1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1
IFI27 interferon, alpha-inducible protein 27
IFI6 interferon, alpha-inducible protein 6
IGHM immunoglobulin heavy constant mu
IRF4 interferon regulatory factor 4
KCNH1 potassium channel, voltage gated eag related subfamily H, member 1
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KDM5B lysine (K)-specific demethylase 5B
KLK8 kallikrein-related peptidase 8
L3MBTL1 l(3)mbt-like 1 (Drosophila)
MAGEB4 melanoma antigen family B4
MAOA monoamine oxidase A
MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase
MRPL41 mitochondrial ribosomal protein L41
MYL4 myosin, light chain 4, alkali; atrial, embryonic
MYOC myocilin, trabecular meshwork inducible glucocorticoid response
MYOZ1 myozenin 1
MYRIP myosin VIIA and Rab interacting protein
NDOR1 NADPH dependent diflavin oxidoreductase 1
NPY2R neuropeptide Y receptor Y2
OBSCN obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
OSBPL10 oxysterol binding protein-like 10
OSGIN1 oxidative stress induced growth inhibitor 1
PAPPA pregnancy-associated plasma protein A, pappalysin 1
PAPPA2 pappalysin 2
PAX3 paired box 3
PIDD1 p53-induced death domain protein 1
PLCH1 phospholipase C, eta 1
PLEKHG3 pleckstrin homology domain containing, family G (with RhoGef domain) member 3
PLG plasminogen
PRAMEF10 PRAME family member 10
PRR34 proline rich 34
RAB6A RAB6A, member RAS oncogene family
RECQL5 RecQ protein-like 5
RHBG Rh family, B glycoprotein (gene/pseudogene)
RIF1 replication timing regulatory factor 1
RNF126P1 ring finger protein 126 pseudogene 1
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin)
SLC16A5 solute carrier family 16 (monocarboxylate transporter), member 5
SLC19A1 solute carrier family 19 (folate transporter), member 1
SLC30A3 solute carrier family 30 (zinc transporter), member 3
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SLCO2A1 solute carrier organic anion transporter family, member 2A1
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
SRCAP Snf2-related CREBBP activator protein
SYNPO synaptopodin
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2)
TCP11L1 t-complex 11, testis-specific-like 1
TEX40 testis expressed 40
THTPA thiamine triphosphatase
TMPRSS4 transmembrane protease, serine 4
TNFRSF14 tumor necrosis factor receptor superfamily, member 14
TPSAB1 tryptase alpha/beta 1
TRIM31 tripartite motif containing 31
TRPV6 transient receptor potential cation channel, subfamily V, member 6
TSC22D4 TSC22 domain family, member 4
UBE2I ubiquitin-conjugating enzyme E2I
WNT10B wingless-type MMTV integration site family, member 10B
ZFPL1 zinc finger protein-like 1
ZNF287 zinc finger protein 287
ZNF76 zinc finger protein 76
ZNF771 zinc finger protein 771

decreased expression

Symbol Name
ABCB8 ATP-binding cassette, sub-family B (MDR/TAP), member 8
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
ACSL4 acyl-CoA synthetase long-chain family member 4
AMT aminomethyltransferase
ANXA2P3 annexin A2 pseudogene 3
ARHGDIG Rho GDP dissociation inhibitor (GDI) gamma
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
ATAD5 ATPase family, AAA domain containing 5
BCL9 B-cell CLL/lymphoma 9
BEX4 brain expressed, X-linked 4
BHLHE41 basic helix-loop-helix family, member e41
C14ORF79 chromosome 14 open reading frame 79
CA5BP1 carbonic anhydrase VB pseudogene 1
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CAMTA2 calmodulin binding transcription activator 2
CAPG capping protein (actin filament), gelsolin-like
CCDC121 coiled-coil domain containing 121
CCDC186 coiled-coil domain containing 186
CCDC85C coiled-coil domain containing 85C
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CENPQ centromere protein Q
CHKB choline kinase beta
CHST10 carbohydrate sulfotransferase 10
CIC capicua transcriptional repressor
CLGN calmegin
CLSPN claspin
COL4A3BP collagen, type IV, alpha 3 (Goodpasture antigen) binding protein
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
CUZD1 CUB and zona pellucida-like domains 1
DGAT1 diacylglycerol O-acyltransferase 1
DSCAM Down syndrome cell adhesion molecule
EFNA4 ephrin-A4
F3 coagulation factor III (thromboplastin, tissue factor)
FADS2 fatty acid desaturase 2
FAM110B family with sequence similarity 110, member B
FSTL3 follistatin-like 3 (secreted glycoprotein)
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
GMPR guanosine monophosphate reductase
GNA14 guanine nucleotide binding protein (G protein), alpha 14
HAMP hepcidin antimicrobial peptide
HAUS6 HAUS augmin-like complex, subunit 6
HIST1H2BC histone cluster 1, H2bc
HMOX1 heme oxygenase 1
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
HOXA4 homeobox A4
IDI2-AS1 IDI2 antisense RNA 1
INPP1 inositol polyphosphate-1-phosphatase
KCTD15 potassium channel tetramerization domain containing 15
KIAA0556 KIAA0556
KITLG KIT ligand
LOC100272216 uncharacterized LOC100272216
LOC257152 uncharacterized LOC257152
LY6G6C lymphocyte antigen 6 complex, locus G6C
MBNL3 muscleblind-like splicing regulator 3
MBTPS2 membrane-bound transcription factor peptidase, site 2
MFGE8 milk fat globule-EGF factor 8 protein
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
MITF microphthalmia-associated transcription factor
NPFFR1 neuropeptide FF receptor 1
NT5DC3 5'-nucleotidase domain containing 3
OVGP1 oviductal glycoprotein 1, 120kDa
OVOL1 ovo-like zinc finger 1
PCDHA5 protocadherin alpha 5
PDGFRL platelet-derived growth factor receptor-like
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PIGH phosphatidylinositol glycan anchor biosynthesis, class H
PPP2R3B protein phosphatase 2, regulatory subunit B'', beta
PTPN14 protein tyrosine phosphatase, non-receptor type 14
PTPRS protein tyrosine phosphatase, receptor type, S
RAB36 RAB36, member RAS oncogene family
RAI2 retinoic acid induced 2
RASAL1 RAS protein activator like 1 (GAP1 like)
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
RHBDD3 rhomboid domain containing 3
RPL23AP32 ribosomal protein L23a pseudogene 32
RWDD3 RWD domain containing 3
S100A9 S100 calcium binding protein A9
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
TBC1D19 TBC1 domain family, member 19
TBX3 T-box 3
TGFB1I1 transforming growth factor beta 1 induced transcript 1
TICAM1 toll-like receptor adaptor molecule 1
TMEM242 transmembrane protein 242
TMUB2 transmembrane and ubiquitin-like domain containing 2
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator
TRAIP TRAF interacting protein
TRMT11 tRNA methyltransferase 11 homolog (S. cerevisiae)
UBTD1 ubiquitin domain containing 1
USB1 U6 snRNA biogenesis 1
USP27X ubiquitin specific peptidase 27, X-linked
VGF VGF nerve growth factor inducible
WDR33 WD repeat domain 33
WDR4 WD repeat domain 4
ZNF134 zinc finger protein 134
ZNF141 zinc finger protein 141
ZNF573 zinc finger protein 573
ZSCAN26 zinc finger and SCAN domain containing 26