| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the ketotifen-1583 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AAAS | achalasia, adrenocortical insufficiency, alacrimia |
| ABHD3 | abhydrolase domain containing 3 |
| ADGRA2 | adhesion G protein-coupled receptor A2 |
| AGRN | agrin |
| AHCYL2 | adenosylhomocysteinase-like 2 |
| ARRB2 | arrestin, beta 2 |
| ATG10 | autophagy related 10 |
| ATXN7L3B | ataxin 7-like 3B |
| AXIN1 | axin 1 |
| BATF | basic leucine zipper transcription factor, ATF-like |
| BBC3 | BCL2 binding component 3 |
| BSCL2 | Berardinelli-Seip congenital lipodystrophy 2 (seipin) |
| C1ORF109 | chromosome 1 open reading frame 109 |
| CASP3 | caspase 3, apoptosis-related cysteine peptidase |
| CCDC88A | coiled-coil domain containing 88A |
| CCPG1 | cell cycle progression 1 |
| CCR1 | chemokine (C-C motif) receptor 1 |
| CD101 | CD101 molecule |
| CNTFR | ciliary neurotrophic factor receptor |
| CROT | carnitine O-octanoyltransferase |
| CTNS | cystinosin, lysosomal cystine transporter |
| CTRC | chymotrypsin C (caldecrin) |
| DGAT1 | diacylglycerol O-acyltransferase 1 |
| DNAAF2 | dynein, axonemal, assembly factor 2 |
| DUS2 | dihydrouridine synthase 2 |
| EFR3B | EFR3 homolog B (S. cerevisiae) |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 |
| ELK1 | ELK1, member of ETS oncogene family |
| EPOR | erythropoietin receptor |
| ETV1 | ets variant 1 |
| FHL3 | four and a half LIM domains 3 |
| FNTB | farnesyltransferase, CAAX box, beta |
| GFOD2 | glucose-fructose oxidoreductase domain containing 2 |
| GIMAP5 | GTPase, IMAP family member 5 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFITM1 | interferon induced transmembrane protein 1 |
| IGSF6 | immunoglobulin superfamily, member 6 |
| IL1RAP | interleukin 1 receptor accessory protein |
| ISYNA1 | inositol-3-phosphate synthase 1 |
| LPL | lipoprotein lipase |
| LUZP1 | leucine zipper protein 1 |
| MAML3 | mastermind-like 3 (Drosophila) |
| MAP2K7 | mitogen-activated protein kinase kinase 7 |
| MCC | mutated in colorectal cancers |
| MED12 | mediator complex subunit 12 |
| MFNG | MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase |
| MPHOSPH9 | M-phase phosphoprotein 9 |
| MRM1 | mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) |
| MS4A6A | membrane-spanning 4-domains, subfamily A, member 6A |
| MST1 | macrophage stimulating 1 |
| MXD4 | MAX dimerization protein 4 |
| N4BP2L1 | NEDD4 binding protein 2-like 1 |
| NCAPH2 | non-SMC condensin II complex, subunit H2 |
| NCOA3 | nuclear receptor coactivator 3 |
| NCR2 | natural cytotoxicity triggering receptor 2 |
| NOD1 | nucleotide-binding oligomerization domain containing 1 |
| NRGN | neurogranin (protein kinase C substrate, RC3) |
| NTRK3 | neurotrophic tyrosine kinase, receptor, type 3 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) |
| PARP16 | poly (ADP-ribose) polymerase family, member 16 |
| PCSK7 | proprotein convertase subtilisin/kexin type 7 |
| PKNOX2 | PBX/knotted 1 homeobox 2 |
| PPRC1 | peroxisome proliferator-activated receptor gamma, coactivator-related 1 |
| PRPF6 | pre-mRNA processing factor 6 |
| PTGIR | prostaglandin I2 (prostacyclin) receptor (IP) |
| RABL6 | RAB, member RAS oncogene family-like 6 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) |
| RANBP3 | RAN binding protein 3 |
| RASL11B | RAS-like, family 11, member B |
| RCE1 | Ras converting CAAX endopeptidase 1 |
| RIN3 | Ras and Rab interactor 3 |
| RPS11 | ribosomal protein S11 |
| RRP9 | ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast) |
| SCARB2 | scavenger receptor class B, member 2 |
| SEMA6A | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A |
| SH3BP2 | SH3-domain binding protein 2 |
| SLC7A8 | solute carrier family 7 (amino acid transporter light chain, L system), member 8 |
| SMPD2 | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) |
| SOGA1 | suppressor of glucose, autophagy associated 1 |
| SPN | sialophorin |
| SPTB | spectrin, beta, erythrocytic |
| SRSF1 | serine/arginine-rich splicing factor 1 |
| SSH3 | slingshot protein phosphatase 3 |
| SUCLG2 | succinate-CoA ligase, GDP-forming, beta subunit |
| TAF12 | TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa |
| TCEB3 | transcription elongation factor B (SIII), polypeptide 3 (110kDa, elongin A) |
| TMEM63A | transmembrane protein 63A |
| TMEM70 | transmembrane protein 70 |
| TRIM33 | tripartite motif containing 33 |
| TRPM3 | transient receptor potential cation channel, subfamily M, member 3 |
| TSSC4 | tumor suppressing subtransferable candidate 4 |
| USF2 | upstream transcription factor 2, c-fos interacting |
| VCX2 | variable charge, X-linked 2 |
| WBP4 | WW domain binding protein 4 |
| WNT10B | wingless-type MMTV integration site family, member 10B |
| ZIM2 | zinc finger, imprinted 2 |
| ZNF408 | zinc finger protein 408 |
| Symbol | Name |
|---|---|
| ABCA11P | ATP-binding cassette, sub-family A (ABC1), member 11, pseudogene |
| AES | amino-terminal enhancer of split |
| ANKZF1 | ankyrin repeat and zinc finger domain containing 1 |
| AP3M2 | adaptor-related protein complex 3, mu 2 subunit |
| APPL1 | adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 |
| ARHGAP10 | Rho GTPase activating protein 10 |
| ASB8 | ankyrin repeat and SOCS box containing 8 |
| ATAD2B | ATPase family, AAA domain containing 2B |
| BRCA1 | breast cancer 1, early onset |
| C12ORF29 | chromosome 12 open reading frame 29 |
| C12ORF43 | chromosome 12 open reading frame 43 |
| C1ORF54 | chromosome 1 open reading frame 54 |
| CARHSP1 | calcium regulated heat stable protein 1, 24kDa |
| CASP8AP2 | caspase 8 associated protein 2 |
| CD248 | CD248 molecule, endosialin |
| COCH | cochlin |
| COMMD8 | COMM domain containing 8 |
| CSTF3 | cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa |
| CYBA | cytochrome b-245, alpha polypeptide |
| DIXDC1 | DIX domain containing 1 |
| DMXL1 | Dmx-like 1 |
| DNA2 | DNA replication helicase/nuclease 2 |
| DNAJA2 | DnaJ (Hsp40) homolog, subfamily A, member 2 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 |
| DPF2 | D4, zinc and double PHD fingers family 2 |
| DROSHA | drosha, ribonuclease type III |
| EGLN2 | egl-9 family hypoxia-inducible factor 2 |
| EMD | emerin |
| FASTKD5 | FAST kinase domains 5 |
| FBXO5 | F-box protein 5 |
| GBAP1 | glucosidase, beta, acid pseudogene 1 |
| GPATCH2 | G patch domain containing 2 |
| GTPBP3 | GTP binding protein 3 (mitochondrial) |
| HACD2 | 3-hydroxyacyl-CoA dehydratase 2 |
| HDAC4 | histone deacetylase 4 |
| HDHD1 | haloacid dehalogenase-like hydrolase domain containing 1 |
| HEATR3 | HEAT repeat containing 3 |
| HIST3H2A | histone cluster 3, H2a |
| HRAS | Harvey rat sarcoma viral oncogene homolog |
| HRSP12 | heat-responsive protein 12 |
| HS1BP3 | HCLS1 binding protein 3 |
| IGFLR1 | IGF-like family receptor 1 |
| IL4R | interleukin 4 receptor |
| KDM3A | lysine (K)-specific demethylase 3A |
| KDM5C | lysine (K)-specific demethylase 5C |
| KIAA1551 | KIAA1551 |
| LIN37 | lin-37 DREAM MuvB core complex component |
| MCAT | malonyl CoA:ACP acyltransferase (mitochondrial) |
| MEST | mesoderm specific transcript |
| MFF | mitochondrial fission factor |
| MMACHC | methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria |
| MOSPD3 | motile sperm domain containing 3 |
| MRPL19 | mitochondrial ribosomal protein L19 |
| NAT9 | N-acetyltransferase 9 (GCN5-related, putative) |
| NDST2 | N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2 |
| NEDD8 | neural precursor cell expressed, developmentally down-regulated 8 |
| NEIL3 | nei endonuclease VIII-like 3 (E. coli) |
| NIP7 | NIP7, nucleolar pre-rRNA processing protein |
| NT5DC3 | 5'-nucleotidase domain containing 3 |
| NUP133 | nucleoporin 133kDa |
| NVL | nuclear VCP-like |
| NXF3 | nuclear RNA export factor 3 |
| OGDH | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) |
| PADI1 | peptidyl arginine deiminase, type I |
| PAQR3 | progestin and adipoQ receptor family member III |
| PI4KA | phosphatidylinositol 4-kinase, catalytic, alpha |
| PIGN | phosphatidylinositol glycan anchor biosynthesis, class N |
| PRKCD | protein kinase C, delta |
| PRPF3 | pre-mRNA processing factor 3 |
| RNF123 | ring finger protein 123 |
| RPL39L | ribosomal protein L39-like |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) |
| SASH3 | SAM and SH3 domain containing 3 |
| SCML1 | sex comb on midleg-like 1 (Drosophila) |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A |
| SH2B2 | SH2B adaptor protein 2 |
| SLC16A7 | solute carrier family 16 (monocarboxylate transporter), member 7 |
| SLPI | secretory leukocyte peptidase inhibitor |
| SNX6 | sorting nexin 6 |
| SSSCA1 | Sjogren syndrome/scleroderma autoantigen 1 |
| STAR | steroidogenic acute regulatory protein |
| STK39 | serine threonine kinase 39 |
| SUSD6 | sushi domain containing 6 |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 |
| TFB2M | transcription factor B2, mitochondrial |
| TIMM9 | translocase of inner mitochondrial membrane 9 homolog (yeast) |
| TIPIN | TIMELESS interacting protein |
| TMEM50B | transmembrane protein 50B |
| TRIM8 | tripartite motif containing 8 |
| TTF2 | transcription termination factor, RNA polymerase II |
| TXLNA | taxilin alpha |
| UBE2NL | ubiquitin-conjugating enzyme E2N-like (gene/pseudogene) |
| URGCP | upregulator of cell proliferation |
| VPS39 | vacuolar protein sorting 39 homolog (S. cerevisiae) |
| WDR19 | WD repeat domain 19 |
| WDR82 | WD repeat domain 82 |
| ZMYM3 | zinc finger, MYM-type 3 |
| ZNF804A | zinc finger protein 804A |
