| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the ketotifen-3200 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 |
| ABCA7 | ATP-binding cassette, sub-family A (ABC1), member 7 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 |
| ADAM19 | ADAM metallopeptidase domain 19 |
| ADCY2 | adenylate cyclase 2 (brain) |
| ADH1B | alcohol dehydrogenase 1B (class I), beta polypeptide |
| AGFG2 | ArfGAP with FG repeats 2 |
| ALDOB | aldolase B, fructose-bisphosphate |
| AMOT | angiomotin |
| ARHGEF11 | Rho guanine nucleotide exchange factor (GEF) 11 |
| ARSD | arylsulfatase D |
| ATF5 | activating transcription factor 5 |
| BCL11A | B-cell CLL/lymphoma 11A (zinc finger protein) |
| BPY2 | basic charge, Y-linked, 2 |
| C1ORF105 | chromosome 1 open reading frame 105 |
| CASKIN2 | CASK interacting protein 2 |
| CCDC134 | coiled-coil domain containing 134 |
| CCDC71 | coiled-coil domain containing 71 |
| CCR1 | chemokine (C-C motif) receptor 1 |
| CD160 | CD160 molecule |
| CD79B | CD79b molecule, immunoglobulin-associated beta |
| CD93 | CD93 molecule |
| CDK18 | cyclin-dependent kinase 18 |
| CEACAM3 | carcinoembryonic antigen-related cell adhesion molecule 3 |
| CFHR4 | complement factor H-related 4 |
| CIB2 | calcium and integrin binding family member 2 |
| COL2A1 | collagen, type II, alpha 1 |
| CREBZF | CREB/ATF bZIP transcription factor |
| CYLD | cylindromatosis (turban tumor syndrome) |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 |
| DCN | decorin |
| DLX4 | distal-less homeobox 4 |
| F2RL3 | coagulation factor II (thrombin) receptor-like 3 |
| FAM129A | family with sequence similarity 129, member A |
| FCGR2C | Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene) |
| FCGR3B | Fc fragment of IgG, low affinity IIIb, receptor (CD16b) |
| FGF12 | fibroblast growth factor 12 |
| FKBP10 | FK506 binding protein 10, 65 kDa |
| FXYD5 | FXYD domain containing ion transport regulator 5 |
| GPR153 | G protein-coupled receptor 153 |
| GPR176 | G protein-coupled receptor 176 |
| GRIN1 | glutamate receptor, ionotropic, N-methyl D-aspartate 1 |
| GSK3A | glycogen synthase kinase 3 alpha |
| GSTA4 | glutathione S-transferase alpha 4 |
| HEPH | hephaestin |
| ICAM1 | intercellular adhesion molecule 1 |
| ICMT | isoprenylcysteine carboxyl methyltransferase |
| IGHMBP2 | immunoglobulin mu binding protein 2 |
| IL1B | interleukin 1, beta |
| INPP4A | inositol polyphosphate-4-phosphatase, type I, 107kDa |
| MGAT2 | mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming |
| MXD4 | MAX dimerization protein 4 |
| MYCN | v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog |
| NME5 | NME/NM23 family member 5 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 |
| NUP188 | nucleoporin 188kDa |
| OSGIN1 | oxidative stress induced growth inhibitor 1 |
| OSMR | oncostatin M receptor |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited |
| PHLDB1 | pleckstrin homology-like domain, family B, member 1 |
| PIGR | polymeric immunoglobulin receptor |
| PLEKHA2 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2 |
| POFUT1 | protein O-fucosyltransferase 1 |
| POU2F2 | POU class 2 homeobox 2 |
| PPP1R9A | protein phosphatase 1, regulatory subunit 9A |
| PPP2R5B | protein phosphatase 2, regulatory subunit B', beta |
| PPP5C | protein phosphatase 5, catalytic subunit |
| PRKCE | protein kinase C, epsilon |
| PRPH | peripherin |
| PSD4 | pleckstrin and Sec7 domain containing 4 |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) |
| RBM12B-AS1 | RBM12B antisense RNA 1 |
| RHO | rhodopsin |
| RNF125 | ring finger protein 125, E3 ubiquitin protein ligase |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| S100A2 | S100 calcium binding protein A2 |
| SCHIP1 | schwannomin interacting protein 1 |
| SIM2 | single-minded family bHLH transcription factor 2 |
| SLC14A2 | solute carrier family 14 (urea transporter), member 2 |
| SLC24A2 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 2 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 |
| SLIT3 | slit homolog 3 (Drosophila) |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) |
| STK17A | serine/threonine kinase 17a |
| STRA6 | stimulated by retinoic acid 6 |
| STX2 | syntaxin 2 |
| TFR2 | transferrin receptor 2 |
| THAP9 | THAP domain containing 9 |
| TMEM19 | transmembrane protein 19 |
| TMLHE | trimethyllysine hydroxylase, epsilon |
| TPSG1 | tryptase gamma 1 |
| TRIB2 | tribbles pseudokinase 2 |
| TSPAN2 | tetraspanin 2 |
| TSPAN9 | tetraspanin 9 |
| UPK2 | uroplakin 2 |
| WIPF1 | WAS/WASL interacting protein family, member 1 |
| ZIC3 | Zic family member 3 |
| ZNF518A | zinc finger protein 518A |
| Symbol | Name |
|---|---|
| ABCC2 | ATP-binding cassette, sub-family C (CFTR/MRP), member 2 |
| ACTG2 | actin, gamma 2, smooth muscle, enteric |
| ADCY7 | adenylate cyclase 7 |
| ALOX5AP | arachidonate 5-lipoxygenase-activating protein |
| ANXA2P3 | annexin A2 pseudogene 3 |
| AOC2 | amine oxidase, copper containing 2 (retina-specific) |
| ARHGDIB | Rho GDP dissociation inhibitor (GDI) beta |
| ARHGEF17 | Rho guanine nucleotide exchange factor (GEF) 17 |
| ART1 | ADP-ribosyltransferase 1 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase |
| C11ORF63 | chromosome 11 open reading frame 63 |
| CAPRIN2 | caprin family member 2 |
| CCBL1 | cysteine conjugate-beta lyase, cytoplasmic |
| CDKN2D | cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) |
| CLIC2 | chloride intracellular channel 2 |
| CLSPN | claspin |
| CNR2 | cannabinoid receptor 2 (macrophage) |
| CORT | cortistatin |
| CRELD1 | cysteine-rich with EGF-like domains 1 |
| CSF1R | colony stimulating factor 1 receptor |
| DCAF13 | DDB1 and CUL4 associated factor 13 |
| DDX58 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 |
| EDAR | ectodysplasin A receptor |
| EN2 | engrailed homeobox 2 |
| ENO2 | enolase 2 (gamma, neuronal) |
| ENO3 | enolase 3 (beta, muscle) |
| EXOC6B | exocyst complex component 6B |
| F3 | coagulation factor III (thromboplastin, tissue factor) |
| FAM131A | family with sequence similarity 131, member A |
| FAM186A | family with sequence similarity 186, member A |
| FBXO2 | F-box protein 2 |
| FBXO4 | F-box protein 4 |
| FGL1 | fibrinogen-like 1 |
| FLT4 | fms-related tyrosine kinase 4 |
| FOXI1 | forkhead box I1 |
| FURIN | furin (paired basic amino acid cleaving enzyme) |
| GABRA2 | gamma-aminobutyric acid (GABA) A receptor, alpha 2 |
| GMPR | guanosine monophosphate reductase |
| GPX1 | glutathione peroxidase 1 |
| GPX2 | glutathione peroxidase 2 |
| HCLS1 | hematopoietic cell-specific Lyn substrate 1 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 |
| HHAT | hedgehog acyltransferase |
| HOXC5 | homeobox C5 |
| HSPA1L | heat shock 70kDa protein 1-like |
| IDI2-AS1 | IDI2 antisense RNA 1 |
| IL4R | interleukin 4 receptor |
| KCNA6 | potassium channel, voltage gated shaker related subfamily A, member 6 |
| KDM5C | lysine (K)-specific demethylase 5C |
| KLF2 | Kruppel-like factor 2 |
| KLF3 | Kruppel-like factor 3 (basic) |
| KRTAP2-4 | keratin associated protein 2-4 |
| LATS1 | large tumor suppressor kinase 1 |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) |
| LDHB | lactate dehydrogenase B |
| LHX1 | LIM homeobox 1 |
| LOC257152 | uncharacterized LOC257152 |
| LPAR4 | lysophosphatidic acid receptor 4 |
| LRRTM2 | leucine rich repeat transmembrane neuronal 2 |
| LYZ | lysozyme |
| MPO | myeloperoxidase |
| MSI1 | musashi RNA-binding protein 1 |
| MTCP1 | mature T-cell proliferation 1 |
| MUC3A | mucin 3A, cell surface associated |
| NAT6 | N-acetyltransferase 6 (GCN5-related) |
| NDE1 | nudE neurodevelopment protein 1 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NPFFR1 | neuropeptide FF receptor 1 |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa |
| OLFML2A | olfactomedin-like 2A |
| OVGP1 | oviductal glycoprotein 1, 120kDa |
| PIGN | phosphatidylinositol glycan anchor biosynthesis, class N |
| PLA2G15 | phospholipase A2, group XV |
| PTGES2 | prostaglandin E synthase 2 |
| PTPRU | protein tyrosine phosphatase, receptor type, U |
| RCAN3 | RCAN family member 3 |
| REM1 | RAS (RAD and GEM)-like GTP-binding 1 |
| RNF122 | ring finger protein 122 |
| RPL13P5 | ribosomal protein L13 pseudogene 5 |
| SH2D4A | SH2 domain containing 4A |
| SLC22A18AS | solute carrier family 22 (organic cation transporter), member 18 antisense |
| SPRY2 | sprouty homolog 2 (Drosophila) |
| SREK1IP1 | SREK1-interacting protein 1 |
| SRGN | serglycin |
| SSBP3 | single stranded DNA binding protein 3 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa |
| TCEB3B | transcription elongation factor B polypeptide 3B (elongin A2) |
| THNSL1 | threonine synthase-like 1 (S. cerevisiae) |
| TRPM4 | transient receptor potential cation channel, subfamily M, member 4 |
| TTC23 | tetratricopeptide repeat domain 23 |
| TUBA3C | tubulin, alpha 3c |
| VIM | vimentin |
| WNT10B | wingless-type MMTV integration site family, member 10B |
| XK | X-linked Kx blood group |
| ZNF137P | zinc finger protein 137, pseudogene |
| ZNF227 | zinc finger protein 227 |
| ZNF230 | zinc finger protein 230 |
| ZNF324 | zinc finger protein 324 |
