| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the ketotifen-7199 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABO | ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 |
| AHCYL2 | adenosylhomocysteinase-like 2 |
| AKR1C2 | aldo-keto reductase family 1, member C2 |
| AQP3 | aquaporin 3 (Gill blood group) |
| ARHGDIA | Rho GDP dissociation inhibitor (GDI) alpha |
| C10ORF88 | chromosome 10 open reading frame 88 |
| C19ORF73 | chromosome 19 open reading frame 73 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) |
| CASP3 | caspase 3, apoptosis-related cysteine peptidase |
| CBX8 | chromobox homolog 8 |
| CCNO | cyclin O |
| CDC14A | cell division cycle 14A |
| CEP290 | centrosomal protein 290kDa |
| CLASP2 | cytoplasmic linker associated protein 2 |
| CLDN1 | claudin 1 |
| COPA | coatomer protein complex, subunit alpha |
| COQ7 | coenzyme Q7 homolog, ubiquinone (yeast) |
| CPD | carboxypeptidase D |
| CPQ | carboxypeptidase Q |
| CTNND2 | catenin (cadherin-associated protein), delta 2 |
| CYP2R1 | cytochrome P450, family 2, subfamily R, polypeptide 1 |
| DICER1 | dicer 1, ribonuclease type III |
| DVL2 | dishevelled segment polarity protein 2 |
| EBF2 | early B-cell factor 2 |
| EDNRA | endothelin receptor type A |
| ERCC4 | excision repair cross-complementation group 4 |
| EXOC5 | exocyst complex component 5 |
| F2RL1 | coagulation factor II (thrombin) receptor-like 1 |
| F8 | coagulation factor VIII, procoagulant component |
| FAM169A | family with sequence similarity 169, member A |
| FAS | Fas cell surface death receptor |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) |
| GGA2 | golgi-associated, gamma adaptin ear containing, ARF binding protein 2 |
| GNAZ | guanine nucleotide binding protein (G protein), alpha z polypeptide |
| GPC4 | glypican 4 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) |
| HPS1 | Hermansky-Pudlak syndrome 1 |
| ISG20 | interferon stimulated exonuclease gene 20kDa |
| KATNB1 | katanin p80 (WD repeat containing) subunit B 1 |
| KIAA0485 | uncharacterized LOC57235 |
| KIAA0930 | KIAA0930 |
| LIMK1 | LIM domain kinase 1 |
| LRRC61 | leucine rich repeat containing 61 |
| LSM4 | LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae) |
| LYPD1 | LY6/PLAUR domain containing 1 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MAP3K8 | mitogen-activated protein kinase kinase kinase 8 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric |
| NDE1 | nudE neurodevelopment protein 1 |
| NDST2 | N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2 |
| NIPAL2 | NIPA-like domain containing 2 |
| OGFOD2 | 2-oxoglutarate and iron-dependent oxygenase domain containing 2 |
| OR7E156P | olfactory receptor, family 7, subfamily E, member 156 pseudogene |
| PARD6A | par-6 family cell polarity regulator alpha |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PEX11A | peroxisomal biogenesis factor 11 alpha |
| PI4K2A | phosphatidylinositol 4-kinase type 2 alpha |
| PIBF1 | progesterone immunomodulatory binding factor 1 |
| PKNOX1 | PBX/knotted 1 homeobox 1 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 |
| PROSC | proline synthetase co-transcribed homolog (bacterial) |
| PRPH | peripherin |
| PRRG1 | proline rich Gla (G-carboxyglutamic acid) 1 |
| PSMD11 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 |
| PTBP3 | polypyrimidine tract binding protein 3 |
| QKI | QKI, KH domain containing, RNA binding |
| RASSF1 | Ras association (RalGDS/AF-6) domain family member 1 |
| RBBP9 | retinoblastoma binding protein 9 |
| RBL1 | retinoblastoma-like 1 |
| RCAN1 | regulator of calcineurin 1 |
| RHOQ | ras homolog family member Q |
| RNASEH2B | ribonuclease H2, subunit B |
| RNF6 | ring finger protein (C3H2C3 type) 6 |
| SDC2 | syndecan 2 |
| SEMA3F | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A |
| SFXN3 | sideroflexin 3 |
| SLC35A2 | solute carrier family 35 (UDP-galactose transporter), member A2 |
| SLC7A9 | solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9 |
| SMEK1 | SMEK homolog 1, suppressor of mek1 (Dictyostelium) |
| SOD2 | superoxide dismutase 2, mitochondrial |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 |
| SPTLC2 | serine palmitoyltransferase, long chain base subunit 2 |
| STAM2 | signal transducing adaptor molecule (SH3 domain and ITAM motif) 2 |
| TAF4B | TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa |
| TBC1D17 | TBC1 domain family, member 17 |
| TEP1 | telomerase-associated protein 1 |
| TFDP2 | transcription factor Dp-2 (E2F dimerization partner 2) |
| TGFB2 | transforming growth factor, beta 2 |
| THBD | thrombomodulin |
| THOC5 | THO complex 5 |
| TNFAIP1 | tumor necrosis factor, alpha-induced protein 1 (endothelial) |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b |
| VDAC3 | voltage-dependent anion channel 3 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 |
| ZNF573 | zinc finger protein 573 |
| ZNF675 | zinc finger protein 675 |
| ZSCAN31 | zinc finger and SCAN domain containing 31 |
| Symbol | Name |
|---|---|
| ACTR3B | ARP3 actin-related protein 3 homolog B (yeast) |
| ARID3A | AT rich interactive domain 3A (BRIGHT-like) |
| ATP8B2 | ATPase, aminophospholipid transporter, class I, type 8B, member 2 |
| B4GALNT1 | beta-1,4-N-acetyl-galactosaminyl transferase 1 |
| BAHD1 | bromo adjacent homology domain containing 1 |
| BAP1 | BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) |
| BHLHB9 | basic helix-loop-helix domain containing, class B, 9 |
| BICD1 | bicaudal D homolog 1 (Drosophila) |
| C11ORF80 | chromosome 11 open reading frame 80 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CASD1 | CAS1 domain containing 1 |
| CDADC1 | cytidine and dCMP deaminase domain containing 1 |
| CEP131 | centrosomal protein 131kDa |
| COL9A2 | collagen, type IX, alpha 2 |
| DECR2 | 2,4-dienoyl CoA reductase 2, peroxisomal |
| DHX57 | DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 |
| DSPP | dentin sialophosphoprotein |
| EPHA2 | EPH receptor A2 |
| FGF23 | fibroblast growth factor 23 |
| FGGY | FGGY carbohydrate kinase domain containing |
| GABRA2 | gamma-aminobutyric acid (GABA) A receptor, alpha 2 |
| GAN | gigaxonin |
| GPX2 | glutathione peroxidase 2 |
| GUCY1B2 | guanylate cyclase 1, soluble, beta 2 (pseudogene) |
| HPS6 | Hermansky-Pudlak syndrome 6 |
| IDI2-AS1 | IDI2 antisense RNA 1 |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| IRX4 | iroquois homeobox 4 |
| KIF16B | kinesin family member 16B |
| KREMEN2 | kringle containing transmembrane protein 2 |
| KRT31 | keratin 31, type I |
| LAMA3 | laminin, alpha 3 |
| LOC390998 | ribosomal protein L10 pseudogene |
| LRFN3 | leucine rich repeat and fibronectin type III domain containing 3 |
| LRRC37A2 | leucine rich repeat containing 37, member A2 |
| LSM14B | LSM14B, SCD6 homolog B (S. cerevisiae) |
| MAP1S | microtubule-associated protein 1S |
| MED15 | mediator complex subunit 15 |
| MED9 | mediator complex subunit 9 |
| MEIS1 | Meis homeobox 1 |
| MITF | microphthalmia-associated transcription factor |
| MMP15 | matrix metallopeptidase 15 (membrane-inserted) |
| NDUFAF7 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 7 |
| NEIL3 | nei endonuclease VIII-like 3 (E. coli) |
| NOTCH1 | notch 1 |
| NR2C2 | nuclear receptor subfamily 2, group C, member 2 |
| NRGN | neurogranin (protein kinase C substrate, RC3) |
| NUP62CL | nucleoporin 62kDa C-terminal like |
| OPA3 | optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) |
| ORAI3 | ORAI calcium release-activated calcium modulator 3 |
| PAIP2B | poly(A) binding protein interacting protein 2B |
| PARP16 | poly (ADP-ribose) polymerase family, member 16 |
| PC | pyruvate carboxylase |
| PCSK7 | proprotein convertase subtilisin/kexin type 7 |
| PICK1 | protein interacting with PRKCA 1 |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PLA2G3 | phospholipase A2, group III |
| PLD2 | phospholipase D2 |
| PLD3 | phospholipase D family, member 3 |
| PLEKHB1 | pleckstrin homology domain containing, family B (evectins) member 1 |
| PPP1R13L | protein phosphatase 1, regulatory subunit 13 like |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RCAN3 | RCAN family member 3 |
| RPAP1 | RNA polymerase II associated protein 1 |
| RPGR | retinitis pigmentosa GTPase regulator |
| SAV1 | salvador family WW domain containing protein 1 |
| SBNO2 | strawberry notch homolog 2 (Drosophila) |
| SCAMP5 | secretory carrier membrane protein 5 |
| SETD1A | SET domain containing 1A |
| SLC26A6 | solute carrier family 26 (anion exchanger), member 6 |
| SLC8B1 | solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 |
| SNX15 | sorting nexin 15 |
| SOWAHC | sosondowah ankyrin repeat domain family member C |
| SOX12 | SRY (sex determining region Y)-box 12 |
| SPATA7 | spermatogenesis associated 7 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 |
| SPTLC3 | serine palmitoyltransferase, long chain base subunit 3 |
| SREK1IP1 | SREK1-interacting protein 1 |
| STRN | striatin, calmodulin binding protein |
| TCTA | T-cell leukemia translocation altered |
| THBS3 | thrombospondin 3 |
| THRAP3 | thyroid hormone receptor associated protein 3 |
| TLN1 | talin 1 |
| TMEM104 | transmembrane protein 104 |
| TNS2 | tensin 2 |
| TPST1 | tyrosylprotein sulfotransferase 1 |
| TRAPPC12 | trafficking protein particle complex 12 |
| TRIM5 | tripartite motif containing 5 |
| TRPV1 | transient receptor potential cation channel, subfamily V, member 1 |
| UBXN6 | UBX domain protein 6 |
| UNC119 | unc-119 homolog (C. elegans) |
| UNKL | unkempt family zinc finger-like |
| VPS9D1 | VPS9 domain containing 1 |
| VWA1 | von Willebrand factor A domain containing 1 |
| ZCWPW1 | zinc finger, CW type with PWWP domain 1 |
| ZMAT5 | zinc finger, matrin-type 5 |
| ZNF318 | zinc finger protein 318 |
| ZNF586 | zinc finger protein 586 |