| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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196 genes differentially expressed following the khellin-1922 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AAAS | achalasia, adrenocortical insufficiency, alacrimia |
| AAMDC | adipogenesis associated, Mth938 domain containing |
| ADCK2 | aarF domain containing kinase 2 |
| ADGRG1 | adhesion G protein-coupled receptor G1 |
| AHCYL2 | adenosylhomocysteinase-like 2 |
| AKAP13 | A kinase (PRKA) anchor protein 13 |
| AMT | aminomethyltransferase |
| ARHGEF7 | Rho guanine nucleotide exchange factor (GEF) 7 |
| ARNTL2 | aryl hydrocarbon receptor nuclear translocator-like 2 |
| BMP7 | bone morphogenetic protein 7 |
| C21ORF33 | chromosome 21 open reading frame 33 |
| C2CD2L | C2CD2-like |
| CARHSP1 | calcium regulated heat stable protein 1, 24kDa |
| CCRL2 | chemokine (C-C motif) receptor-like 2 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CHAF1A | chromatin assembly factor 1, subunit A (p150) |
| CHAF1B | chromatin assembly factor 1, subunit B (p60) |
| CIZ1 | CDKN1A interacting zinc finger protein 1 |
| CLU | clusterin |
| CRTC1 | CREB regulated transcription coactivator 1 |
| CTSZ | cathepsin Z |
| DHX38 | DEAH (Asp-Glu-Ala-His) box polypeptide 38 |
| DTX4 | deltex 4, E3 ubiquitin ligase |
| DUSP13 | dual specificity phosphatase 13 |
| DUSP6 | dual specificity phosphatase 6 |
| EGR4 | early growth response 4 |
| ESRRA | estrogen-related receptor alpha |
| FAM65A | family with sequence similarity 65, member A |
| FCGRT | Fc fragment of IgG, receptor, transporter, alpha |
| FGFR1 | fibroblast growth factor receptor 1 |
| GATA2 | GATA binding protein 2 |
| GLG1 | golgi glycoprotein 1 |
| GPR21 | G protein-coupled receptor 21 |
| HCFC1R1 | host cell factor C1 regulator 1 (XPO1 dependent) |
| HK2 | hexokinase 2 |
| HPS6 | Hermansky-Pudlak syndrome 6 |
| JRK | Jrk homolog (mouse) |
| KLF6 | Kruppel-like factor 6 |
| KRT15 | keratin 15, type I |
| KRT4 | keratin 4, type II |
| LAD1 | ladinin 1 |
| LSR | lipolysis stimulated lipoprotein receptor |
| LUC7L | LUC7-like (S. cerevisiae) |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MBD3 | methyl-CpG binding domain protein 3 |
| MED6 | mediator complex subunit 6 |
| MFGE8 | milk fat globule-EGF factor 8 protein |
| MMP25 | matrix metallopeptidase 25 |
| MRPL57 | mitochondrial ribosomal protein L57 |
| MSH3 | mutS homolog 3 |
| MYO1C | myosin IC |
| NAB2 | NGFI-A binding protein 2 (EGR1 binding protein 2) |
| NHEJ1 | nonhomologous end-joining factor 1 |
| NOTCH2 | notch 2 |
| NSUN5P1 | NOP2/Sun domain family, member 5 pseudogene 1 |
| NUDT11 | nudix (nucleoside diphosphate linked moiety X)-type motif 11 |
| ORAI2 | ORAI calcium release-activated calcium modulator 2 |
| PACSIN3 | protein kinase C and casein kinase substrate in neurons 3 |
| PCGF2 | polycomb group ring finger 2 |
| PCSK7 | proprotein convertase subtilisin/kexin type 7 |
| PIDD1 | p53-induced death domain protein 1 |
| PIEZO1 | piezo-type mechanosensitive ion channel component 1 |
| PKP4 | plakophilin 4 |
| POLD4 | polymerase (DNA-directed), delta 4, accessory subunit |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor |
| PPM1G | protein phosphatase, Mg2+/Mn2+ dependent, 1G |
| PPP2R5B | protein phosphatase 2, regulatory subunit B', beta |
| PYGB | phosphorylase, glycogen; brain |
| RAB4B | RAB4B, member RAS oncogene family |
| RECQL5 | RecQ protein-like 5 |
| RGS11 | regulator of G-protein signaling 11 |
| RUSC2 | RUN and SH3 domain containing 2 |
| SCYL3 | SCY1-like 3 (S. cerevisiae) |
| SDHA | succinate dehydrogenase complex, subunit A, flavoprotein (Fp) |
| SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SETDB1 | SET domain, bifurcated 1 |
| SFN | stratifin |
| SH2D4A | SH2 domain containing 4A |
| SHARPIN | SHANK-associated RH domain interactor |
| SNAPC4 | small nuclear RNA activating complex, polypeptide 4, 190kDa |
| SNPH | syntaphilin |
| SORBS3 | sorbin and SH3 domain containing 3 |
| SPTB | spectrin, beta, erythrocytic |
| STK19 | serine/threonine kinase 19 |
| TAF12 | TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa |
| TET3 | tet methylcytosine dioxygenase 3 |
| THRB | thyroid hormone receptor, beta |
| TLR2 | toll-like receptor 2 |
| TMEM104 | transmembrane protein 104 |
| TOLLIP | toll interacting protein |
| TRMT1 | tRNA methyltransferase 1 homolog (S. cerevisiae) |
| TTLL4 | tubulin tyrosine ligase-like family member 4 |
| UBE2O | ubiquitin-conjugating enzyme E2O |
| USF2 | upstream transcription factor 2, c-fos interacting |
| VIPR1 | vasoactive intestinal peptide receptor 1 |
| WDR4 | WD repeat domain 4 |
| ZNF134 | zinc finger protein 134 |
| Symbol | Name |
|---|---|
| ABCD3 | ATP-binding cassette, sub-family D (ALD), member 3 |
| ABHD3 | abhydrolase domain containing 3 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 |
| ACTL6A | actin-like 6A |
| AGO2 | argonaute RISC catalytic component 2 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 |
| ANKRD10 | ankyrin repeat domain 10 |
| ARFGAP3 | ADP-ribosylation factor GTPase activating protein 3 |
| ARMT1 | acidic residue methyltransferase 1 |
| C1D | C1D nuclear receptor corepressor |
| C1ORF109 | chromosome 1 open reading frame 109 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 |
| CDC23 | cell division cycle 23 |
| CDK8 | cyclin-dependent kinase 8 |
| CHML | choroideremia-like (Rab escort protein 2) |
| CHORDC1 | cysteine and histidine-rich domain (CHORD) containing 1 |
| CSGALNACT2 | chondroitin sulfate N-acetylgalactosaminyltransferase 2 |
| CXCL6 | chemokine (C-X-C motif) ligand 6 |
| DBF4 | DBF4 zinc finger |
| DNAJC24 | DnaJ (Hsp40) homolog, subfamily C, member 24 |
| DNASE1L1 | deoxyribonuclease I-like 1 |
| DPM1 | dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit |
| DPYD | dihydropyrimidine dehydrogenase |
| ECT2 | epithelial cell transforming 2 |
| EPM2AIP1 | EPM2A (laforin) interacting protein 1 |
| FAM179B | family with sequence similarity 179, member B |
| FAM3C | family with sequence similarity 3, member C |
| FAM53B | family with sequence similarity 53, member B |
| FANCL | Fanconi anemia, complementation group L |
| FKBP1B | FK506 binding protein 1B, 12.6 kDa |
| FPGT | fucose-1-phosphate guanylyltransferase |
| GCLM | glutamate-cysteine ligase, modifier subunit |
| HIST1H2BC | histone cluster 1, H2bc |
| HMGB2 | high mobility group box 2 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IFT57 | intraflagellar transport 57 |
| IRF6 | interferon regulatory factor 6 |
| ISOC1 | isochorismatase domain containing 1 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 |
| KCTD3 | potassium channel tetramerization domain containing 3 |
| LGMN | legumain |
| LRCH3 | leucine-rich repeats and calponin homology (CH) domain containing 3 |
| MAD2L1 | MAD2 mitotic arrest deficient-like 1 (yeast) |
| MICU2 | mitochondrial calcium uptake 2 |
| MIS12 | MIS12 kinetochore complex component |
| MORC3 | MORC family CW-type zinc finger 3 |
| MSMO1 | methylsterol monooxygenase 1 |
| MSX1 | msh homeobox 1 |
| NAA50 | N(alpha)-acetyltransferase 50, NatE catalytic subunit |
| NUCB2 | nucleobindin 2 |
| NUP43 | nucleoporin 43kDa |
| OGFRL1 | opioid growth factor receptor-like 1 |
| PCNXL4 | pecanex-like 4 (Drosophila) |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha |
| PLCD1 | phospholipase C, delta 1 |
| PLEKHF2 | pleckstrin homology domain containing, family F (with FYVE domain) member 2 |
| PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme |
| PRSS23 | protease, serine, 23 |
| PTBP2 | polypyrimidine tract binding protein 2 |
| PTX3 | pentraxin 3, long |
| QTRTD1 | queuine tRNA-ribosyltransferase domain containing 1 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit |
| RIPPLY3 | ripply transcriptional repressor 3 |
| SCG5 | secretogranin V |
| SDHAF3 | succinate dehydrogenase complex assembly factor 3 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 |
| SETD1B | SET domain containing 1B |
| SGMS1 | sphingomyelin synthase 1 |
| SIRT1 | sirtuin 1 |
| SLC25A24 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24 |
| SLC31A2 | solute carrier family 31 (copper transporter), member 2 |
| SLMO2 | slowmo homolog 2 (Drosophila) |
| SOAT1 | sterol O-acyltransferase 1 |
| SRP9 | signal recognition particle 9kDa |
| TAF11 | TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 28kDa |
| TBX3 | T-box 3 |
| TCEAL4 | transcription elongation factor A (SII)-like 4 |
| TMEM14A | transmembrane protein 14A |
| TOP2B | topoisomerase (DNA) II beta 180kDa |
| TRIM58 | tripartite motif containing 58 |
| TRPS1 | trichorhinophalangeal syndrome I |
| TTI2 | TELO2 interacting protein 2 |
| UBE2NL | ubiquitin-conjugating enzyme E2N-like (gene/pseudogene) |
| UEVLD | UEV and lactate/malate dehyrogenase domains |
| UGDH | UDP-glucose 6-dehydrogenase |
| UNC50 | unc-50 homolog (C. elegans) |
| VCPKMT | valosin containing protein lysine (K) methyltransferase |
| VPS39 | vacuolar protein sorting 39 homolog (S. cerevisiae) |
| VPS4B | vacuolar protein sorting 4 homolog B (S. cerevisiae) |
| WLS | wntless Wnt ligand secretion mediator |
| ZBTB11 | zinc finger and BTB domain containing 11 |
| ZNF184 | zinc finger protein 184 |
| ZNF189 | zinc finger protein 189 |
| ZNF211 | zinc finger protein 211 |
| ZNF35 | zinc finger protein 35 |
| ZNF468 | zinc finger protein 468 |
| ZZZ3 | zinc finger, ZZ-type containing 3 |