khellin-1922 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the khellin-1922 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAAS achalasia, adrenocortical insufficiency, alacrimia
AAMDC adipogenesis associated, Mth938 domain containing
ADCK2 aarF domain containing kinase 2
ADGRG1 adhesion G protein-coupled receptor G1
AHCYL2 adenosylhomocysteinase-like 2
AKAP13 A kinase (PRKA) anchor protein 13
AMT aminomethyltransferase
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7
ARNTL2 aryl hydrocarbon receptor nuclear translocator-like 2
BMP7 bone morphogenetic protein 7
C21ORF33 chromosome 21 open reading frame 33
C2CD2L C2CD2-like
CARHSP1 calcium regulated heat stable protein 1, 24kDa
CCRL2 chemokine (C-C motif) receptor-like 2
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHAF1A chromatin assembly factor 1, subunit A (p150)
CHAF1B chromatin assembly factor 1, subunit B (p60)
CIZ1 CDKN1A interacting zinc finger protein 1
CLU clusterin
CRTC1 CREB regulated transcription coactivator 1
CTSZ cathepsin Z
DHX38 DEAH (Asp-Glu-Ala-His) box polypeptide 38
DTX4 deltex 4, E3 ubiquitin ligase
DUSP13 dual specificity phosphatase 13
DUSP6 dual specificity phosphatase 6
EGR4 early growth response 4
ESRRA estrogen-related receptor alpha
FAM65A family with sequence similarity 65, member A
FCGRT Fc fragment of IgG, receptor, transporter, alpha
FGFR1 fibroblast growth factor receptor 1
GATA2 GATA binding protein 2
GLG1 golgi glycoprotein 1
GPR21 G protein-coupled receptor 21
HCFC1R1 host cell factor C1 regulator 1 (XPO1 dependent)
HK2 hexokinase 2
HPS6 Hermansky-Pudlak syndrome 6
JRK Jrk homolog (mouse)
KLF6 Kruppel-like factor 6
KRT15 keratin 15, type I
KRT4 keratin 4, type II
LAD1 ladinin 1
LSR lipolysis stimulated lipoprotein receptor
LUC7L LUC7-like (S. cerevisiae)
MAST3 microtubule associated serine/threonine kinase 3
MBD3 methyl-CpG binding domain protein 3
MED6 mediator complex subunit 6
MFGE8 milk fat globule-EGF factor 8 protein
MMP25 matrix metallopeptidase 25
MRPL57 mitochondrial ribosomal protein L57
MSH3 mutS homolog 3
MYO1C myosin IC
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2)
NHEJ1 nonhomologous end-joining factor 1
NOTCH2 notch 2
NSUN5P1 NOP2/Sun domain family, member 5 pseudogene 1
NUDT11 nudix (nucleoside diphosphate linked moiety X)-type motif 11
ORAI2 ORAI calcium release-activated calcium modulator 2
PACSIN3 protein kinase C and casein kinase substrate in neurons 3
PCGF2 polycomb group ring finger 2
PCSK7 proprotein convertase subtilisin/kexin type 7
PIDD1 p53-induced death domain protein 1
PIEZO1 piezo-type mechanosensitive ion channel component 1
PKP4 plakophilin 4
POLD4 polymerase (DNA-directed), delta 4, accessory subunit
PPDPF pancreatic progenitor cell differentiation and proliferation factor
PPM1G protein phosphatase, Mg2+/Mn2+ dependent, 1G
PPP2R5B protein phosphatase 2, regulatory subunit B', beta
PYGB phosphorylase, glycogen; brain
RAB4B RAB4B, member RAS oncogene family
RECQL5 RecQ protein-like 5
RGS11 regulator of G-protein signaling 11
RUSC2 RUN and SH3 domain containing 2
SCYL3 SCY1-like 3 (S. cerevisiae)
SDHA succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
SETD8 SET domain containing (lysine methyltransferase) 8
SETDB1 SET domain, bifurcated 1
SFN stratifin
SH2D4A SH2 domain containing 4A
SHARPIN SHANK-associated RH domain interactor
SNAPC4 small nuclear RNA activating complex, polypeptide 4, 190kDa
SNPH syntaphilin
SORBS3 sorbin and SH3 domain containing 3
SPTB spectrin, beta, erythrocytic
STK19 serine/threonine kinase 19
TAF12 TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa
TET3 tet methylcytosine dioxygenase 3
THRB thyroid hormone receptor, beta
TLR2 toll-like receptor 2
TMEM104 transmembrane protein 104
TOLLIP toll interacting protein
TRMT1 tRNA methyltransferase 1 homolog (S. cerevisiae)
TTLL4 tubulin tyrosine ligase-like family member 4
UBE2O ubiquitin-conjugating enzyme E2O
USF2 upstream transcription factor 2, c-fos interacting
VIPR1 vasoactive intestinal peptide receptor 1
WDR4 WD repeat domain 4
ZNF134 zinc finger protein 134

decreased expression

Symbol Name
ABCD3 ATP-binding cassette, sub-family D (ALD), member 3
ABHD3 abhydrolase domain containing 3
ACSL4 acyl-CoA synthetase long-chain family member 4
ACTL6A actin-like 6A
AGO2 argonaute RISC catalytic component 2
AMIGO2 adhesion molecule with Ig-like domain 2
ANKRD10 ankyrin repeat domain 10
ARFGAP3 ADP-ribosylation factor GTPase activating protein 3
ARMT1 acidic residue methyltransferase 1
C1D C1D nuclear receptor corepressor
C1ORF109 chromosome 1 open reading frame 109
CAPZA2 capping protein (actin filament) muscle Z-line, alpha 2
CDC23 cell division cycle 23
CDK8 cyclin-dependent kinase 8
CHML choroideremia-like (Rab escort protein 2)
CHORDC1 cysteine and histidine-rich domain (CHORD) containing 1
CSGALNACT2 chondroitin sulfate N-acetylgalactosaminyltransferase 2
CXCL6 chemokine (C-X-C motif) ligand 6
DBF4 DBF4 zinc finger
DNAJC24 DnaJ (Hsp40) homolog, subfamily C, member 24
DNASE1L1 deoxyribonuclease I-like 1
DPM1 dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit
DPYD dihydropyrimidine dehydrogenase
ECT2 epithelial cell transforming 2
EPM2AIP1 EPM2A (laforin) interacting protein 1
FAM179B family with sequence similarity 179, member B
FAM3C family with sequence similarity 3, member C
FAM53B family with sequence similarity 53, member B
FANCL Fanconi anemia, complementation group L
FKBP1B FK506 binding protein 1B, 12.6 kDa
FPGT fucose-1-phosphate guanylyltransferase
GCLM glutamate-cysteine ligase, modifier subunit
HIST1H2BC histone cluster 1, H2bc
HMGB2 high mobility group box 2
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IFT57 intraflagellar transport 57
IRF6 interferon regulatory factor 6
ISOC1 isochorismatase domain containing 1
ITFG1 integrin alpha FG-GAP repeat containing 1
KCTD3 potassium channel tetramerization domain containing 3
LGMN legumain
LRCH3 leucine-rich repeats and calponin homology (CH) domain containing 3
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast)
MICU2 mitochondrial calcium uptake 2
MIS12 MIS12 kinetochore complex component
MORC3 MORC family CW-type zinc finger 3
MSMO1 methylsterol monooxygenase 1
MSX1 msh homeobox 1
NAA50 N(alpha)-acetyltransferase 50, NatE catalytic subunit
NUCB2 nucleobindin 2
NUP43 nucleoporin 43kDa
OGFRL1 opioid growth factor receptor-like 1
PCNXL4 pecanex-like 4 (Drosophila)
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha
PLCD1 phospholipase C, delta 1
PLEKHF2 pleckstrin homology domain containing, family F (with FYVE domain) member 2
PLEKHO2 pleckstrin homology domain containing, family O member 2
PPP1CB protein phosphatase 1, catalytic subunit, beta isozyme
PRSS23 protease, serine, 23
PTBP2 polypyrimidine tract binding protein 2
PTX3 pentraxin 3, long
QTRTD1 queuine tRNA-ribosyltransferase domain containing 1
REV3L REV3-like, polymerase (DNA directed), zeta, catalytic subunit
RIPPLY3 ripply transcriptional repressor 3
SCG5 secretogranin V
SDHAF3 succinate dehydrogenase complex assembly factor 3
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SETD1B SET domain containing 1B
SGMS1 sphingomyelin synthase 1
SIRT1 sirtuin 1
SLC25A24 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24
SLC31A2 solute carrier family 31 (copper transporter), member 2
SLMO2 slowmo homolog 2 (Drosophila)
SOAT1 sterol O-acyltransferase 1
SRP9 signal recognition particle 9kDa
TAF11 TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 28kDa
TBX3 T-box 3
TCEAL4 transcription elongation factor A (SII)-like 4
TMEM14A transmembrane protein 14A
TOP2B topoisomerase (DNA) II beta 180kDa
TRIM58 tripartite motif containing 58
TRPS1 trichorhinophalangeal syndrome I
TTI2 TELO2 interacting protein 2
UBE2NL ubiquitin-conjugating enzyme E2N-like (gene/pseudogene)
UEVLD UEV and lactate/malate dehyrogenase domains
UGDH UDP-glucose 6-dehydrogenase
UNC50 unc-50 homolog (C. elegans)
VCPKMT valosin containing protein lysine (K) methyltransferase
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
VPS4B vacuolar protein sorting 4 homolog B (S. cerevisiae)
WLS wntless Wnt ligand secretion mediator
ZBTB11 zinc finger and BTB domain containing 11
ZNF184 zinc finger protein 184
ZNF189 zinc finger protein 189
ZNF211 zinc finger protein 211
ZNF35 zinc finger protein 35
ZNF468 zinc finger protein 468
ZZZ3 zinc finger, ZZ-type containing 3