| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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196 genes differentially expressed following the khellin-2004 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACPP | acid phosphatase, prostate |
| ADAM15 | ADAM metallopeptidase domain 15 |
| AKAP13 | A kinase (PRKA) anchor protein 13 |
| ALDH6A1 | aldehyde dehydrogenase 6 family, member A1 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 |
| APOC4 | apolipoprotein C-IV |
| ARIH2 | ariadne RBR E3 ubiquitin protein ligase 2 |
| ARR3 | arrestin 3, retinal (X-arrestin) |
| BST1 | bone marrow stromal cell antigen 1 |
| C9ORF9 | chromosome 9 open reading frame 9 |
| CA7 | carbonic anhydrase VII |
| CALB2 | calbindin 2 |
| CC2D1A | coiled-coil and C2 domain containing 1A |
| CCDC94 | coiled-coil domain containing 94 |
| CD37 | CD37 molecule |
| CD82 | CD82 molecule |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) |
| CEACAM7 | carcinoembryonic antigen-related cell adhesion molecule 7 |
| CHD3 | chromodomain helicase DNA binding protein 3 |
| CLSPN | claspin |
| CSTF2T | cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant |
| CYP27A1 | cytochrome P450, family 27, subfamily A, polypeptide 1 |
| DNAJC4 | DnaJ (Hsp40) homolog, subfamily C, member 4 |
| DUSP2 | dual specificity phosphatase 2 |
| DUSP6 | dual specificity phosphatase 6 |
| EIF1 | eukaryotic translation initiation factor 1 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 |
| ERBB2IP | erbb2 interacting protein |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| EXOG | endo/exonuclease (5'-3'), endonuclease G-like |
| FAM153A | family with sequence similarity 153, member A |
| FBXO31 | F-box protein 31 |
| FCGR2C | Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene) |
| FGL1 | fibrinogen-like 1 |
| FNBP1 | formin binding protein 1 |
| FOXJ3 | forkhead box J3 |
| GK | glycerol kinase |
| GNA11 | guanine nucleotide binding protein (G protein), alpha 11 (Gq class) |
| GNG3 | guanine nucleotide binding protein (G protein), gamma 3 |
| GPR12 | G protein-coupled receptor 12 |
| GRK5 | G protein-coupled receptor kinase 5 |
| HTR4 | 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled |
| IL1RAP | interleukin 1 receptor accessory protein |
| IL6ST | interleukin 6 signal transducer |
| ILF3 | interleukin enhancer binding factor 3, 90kDa |
| KCNMB1 | potassium channel subfamily M regulatory beta subunit 1 |
| KCTD3 | potassium channel tetramerization domain containing 3 |
| KIF3B | kinesin family member 3B |
| LENEP | lens epithelial protein |
| LMTK1 | lemur tail kinase 1 |
| LRRC37A2 | leucine rich repeat containing 37, member A2 |
| LUZP1 | leucine zipper protein 1 |
| MAGED2 | melanoma antigen family D2 |
| MAP2K7 | mitogen-activated protein kinase kinase 7 |
| MAST2 | microtubule associated serine/threonine kinase 2 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 |
| MGAM | maltase-glucoamylase |
| MID2 | midline 2 |
| MOB3B | MOB kinase activator 3B |
| MPP2 | membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) |
| N4BP1 | NEDD4 binding protein 1 |
| NIP7 | NIP7, nucleolar pre-rRNA processing protein |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| NUP214 | nucleoporin 214kDa |
| OR2S2 | olfactory receptor, family 2, subfamily S, member 2 (gene/pseudogene) |
| PDE8A | phosphodiesterase 8A |
| PECAM1 | platelet/endothelial cell adhesion molecule 1 |
| PIGZ | phosphatidylinositol glycan anchor biosynthesis, class Z |
| PIP4K2C | phosphatidylinositol-5-phosphate 4-kinase, type II, gamma |
| PLCD1 | phospholipase C, delta 1 |
| PLD2 | phospholipase D2 |
| PLEK2 | pleckstrin 2 |
| POR | P450 (cytochrome) oxidoreductase |
| PPP2R4 | protein phosphatase 2A activator, regulatory subunit 4 |
| PTBP3 | polypyrimidine tract binding protein 3 |
| PTP4A1 | protein tyrosine phosphatase type IVA, member 1 |
| PVR | poliovirus receptor |
| RABL6 | RAB, member RAS oncogene family-like 6 |
| RPS11 | ribosomal protein S11 |
| RYK | receptor-like tyrosine kinase |
| SAG | S-antigen; retina and pineal gland (arrestin) |
| SGSM3 | small G protein signaling modulator 3 |
| SIRPA | signal-regulatory protein alpha |
| SLC10A1 | solute carrier family 10 (sodium/bile acid cotransporter), member 1 |
| SLC19A1 | solute carrier family 19 (folate transporter), member 1 |
| SLC22A14 | solute carrier family 22, member 14 |
| SLC22A18 | solute carrier family 22, member 18 |
| SLC39A1 | solute carrier family 39 (zinc transporter), member 1 |
| SPDEF | SAM pointed domain containing ETS transcription factor |
| SULT1B1 | sulfotransferase family, cytosolic, 1B, member 1 |
| TBC1D29 | TBC1 domain family, member 29 |
| TDRD3 | tudor domain containing 3 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 |
| TNFSF13 | tumor necrosis factor (ligand) superfamily, member 13 |
| TTLL5 | tubulin tyrosine ligase-like family member 5 |
| ZC3H7B | zinc finger CCCH-type containing 7B |
| ZNF24 | zinc finger protein 24 |
| ZNF721 | zinc finger protein 721 |
| Symbol | Name |
|---|---|
| ADM | adrenomedullin |
| ARID3A | AT rich interactive domain 3A (BRIGHT-like) |
| ASCC1 | activating signal cointegrator 1 complex subunit 1 |
| ASL | argininosuccinate lyase |
| ATG4A | autophagy related 4A, cysteine peptidase |
| BLMH | bleomycin hydrolase |
| C11ORF68 | chromosome 11 open reading frame 68 |
| C16ORF62 | chromosome 16 open reading frame 62 |
| CCBL1 | cysteine conjugate-beta lyase, cytoplasmic |
| CD2AP | CD2-associated protein |
| CD302 | CD302 molecule |
| CDK9 | cyclin-dependent kinase 9 |
| CDT1 | chromatin licensing and DNA replication factor 1 |
| CEP72 | centrosomal protein 72kDa |
| COG7 | component of oligomeric golgi complex 7 |
| CRYBB2P1 | crystallin, beta B2 pseudogene 1 |
| CTSL | cathepsin L |
| DAD1 | defender against cell death 1 |
| DDX31 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 |
| DENND5A | DENN/MADD domain containing 5A |
| DGCR11 | DiGeorge syndrome critical region gene 11 (non-protein coding) |
| DIABLO | diablo, IAP-binding mitochondrial protein |
| DPH2 | DPH2 homolog (S. cerevisiae) |
| DUSP12 | dual specificity phosphatase 12 |
| EDEM1 | ER degradation enhancer, mannosidase alpha-like 1 |
| FAM222B | family with sequence similarity 222, member B |
| FAM63A | family with sequence similarity 63, member A |
| FBXO46 | F-box protein 46 |
| GATAD2A | GATA zinc finger domain containing 2A |
| GOLPH3L | golgi phosphoprotein 3-like |
| GSR | glutathione reductase |
| GTF2B | general transcription factor IIB |
| H2BFS | H2B histone family, member S (pseudogene) |
| HINFP | histone H4 transcription factor |
| HIST1H1E | histone cluster 1, H1e |
| HK1 | hexokinase 1 |
| IFNA17 | interferon, alpha 17 |
| IMPACT | impact RWD domain protein |
| IP6K1 | inositol hexakisphosphate kinase 1 |
| ISG15 | ISG15 ubiquitin-like modifier |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 |
| KDM5C | lysine (K)-specific demethylase 5C |
| KIZ | kizuna centrosomal protein |
| KLHL21 | kelch-like family member 21 |
| KRI1 | KRI1 homolog (S. cerevisiae) |
| LBR | lamin B receptor |
| LIMD2 | LIM domain containing 2 |
| LMNB1 | lamin B1 |
| LPPR3 | lipid phosphate phosphatase-related protein type 3 |
| LXN | latexin |
| MAD1L1 | MAD1 mitotic arrest deficient-like 1 (yeast) |
| MECR | mitochondrial trans-2-enoyl-CoA reductase |
| MFF | mitochondrial fission factor |
| MFHAS1 | malignant fibrous histiocytoma amplified sequence 1 |
| MT1HL1 | metallothionein 1H-like 1 |
| NDE1 | nudE neurodevelopment protein 1 |
| NHEJ1 | nonhomologous end-joining factor 1 |
| NOD1 | nucleotide-binding oligomerization domain containing 1 |
| NOL12 | nucleolar protein 12 |
| NOL6 | nucleolar protein 6 (RNA-associated) |
| OGDH | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) |
| OXSR1 | oxidative stress responsive 1 |
| P2RY2 | purinergic receptor P2Y, G-protein coupled, 2 |
| PARG | poly (ADP-ribose) glycohydrolase |
| PCSK7 | proprotein convertase subtilisin/kexin type 7 |
| PEMT | phosphatidylethanolamine N-methyltransferase |
| PIEZO1 | piezo-type mechanosensitive ion channel component 1 |
| PIK3CA | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha |
| PJA1 | praja ring finger 1, E3 ubiquitin protein ligase |
| PKN1 | protein kinase N1 |
| PLAG1 | pleiomorphic adenoma gene 1 |
| PMVK | phosphomevalonate kinase |
| PNRC1 | proline-rich nuclear receptor coactivator 1 |
| POGK | pogo transposable element with KRAB domain |
| RAB4B | RAB4B, member RAS oncogene family |
| RGCC | regulator of cell cycle |
| RPUSD2 | RNA pseudouridylate synthase domain containing 2 |
| SECISBP2 | SECIS binding protein 2 |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
| SETDB1 | SET domain, bifurcated 1 |
| SHPK | sedoheptulokinase |
| SLC7A7 | solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 |
| SMYD5 | SMYD family member 5 |
| SNORA21 | small nucleolar RNA, H/ACA box 21 |
| SNX6 | sorting nexin 6 |
| SPR | sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) |
| STRA13 | stimulated by retinoic acid 13 |
| SUN2 | Sad1 and UNC84 domain containing 2 |
| TCTN2 | tectonic family member 2 |
| TMED1 | transmembrane emp24 protein transport domain containing 1 |
| TMEM104 | transmembrane protein 104 |
| TMEM14A | transmembrane protein 14A |
| TNF | tumor necrosis factor |
| UNC93B1 | unc-93 homolog B1 (C. elegans) |
| VASP | vasodilator-stimulated phosphoprotein |
| WNT10B | wingless-type MMTV integration site family, member 10B |
| ZNF140 | zinc finger protein 140 |
| ZNF408 | zinc finger protein 408 |