khellin-4987 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the khellin-4987 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AGGF1 angiogenic factor with G patch and FHA domains 1
APOM apolipoprotein M
ARNT aryl hydrocarbon receptor nuclear translocator
ATP2A3 ATPase, Ca++ transporting, ubiquitous
ATP6V1G2 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2
B9D1 B9 protein domain 1
BMP8B bone morphogenetic protein 8b
BTG2 BTG family, member 2
C3AR1 complement component 3a receptor 1
CASP2 caspase 2, apoptosis-related cysteine peptidase
CCDC6 coiled-coil domain containing 6
CCNO cyclin O
CD82 CD82 molecule
CDK13 cyclin-dependent kinase 13
CES3 carboxylesterase 3
CFAP69 cilia and flagella associated protein 69
CNPPD1 cyclin Pas1/PHO80 domain containing 1
CSF1R colony stimulating factor 1 receptor
CUL2 cullin 2
DAZAP2 DAZ associated protein 2
DOCK6 dedicator of cytokinesis 6
EPHX2 epoxide hydrolase 2, cytoplasmic
ETV5 ets variant 5
GLB1L galactosidase, beta 1-like
GPATCH4 G patch domain containing 4
GPR137 G protein-coupled receptor 137
GPR27 G protein-coupled receptor 27
HDAC7 histone deacetylase 7
HLA-C major histocompatibility complex, class I, C
HOMER3 homer scaffolding protein 3
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
IDS iduronate 2-sulfatase
IFT27 intraflagellar transport 27
IQCC IQ motif containing C
JAM3 junctional adhesion molecule 3
KCNIP1 Kv channel interacting protein 1
KRT19P2 keratin 19 pseudogene 2
LMAN1 lectin, mannose-binding, 1
LRP6 low density lipoprotein receptor-related protein 6
LRRC37A3 leucine rich repeat containing 37, member A3
MAP2K7 mitogen-activated protein kinase kinase 7
MAST3 microtubule associated serine/threonine kinase 3
MGC12488
MOBP myelin-associated oligodendrocyte basic protein
MRPS18C mitochondrial ribosomal protein S18C
NF2 neurofibromin 2 (merlin)
NLE1 notchless homolog 1 (Drosophila)
NME5 NME/NM23 family member 5
NPIPB3 nuclear pore complex interacting protein family, member B3
OR2B6 olfactory receptor, family 2, subfamily B, member 6
PBX2 pre-B-cell leukemia homeobox 2
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PCDHB13 protocadherin beta 13
PCDHGB5 protocadherin gamma subfamily B, 5
PCNX pecanex homolog (Drosophila)
PCYT1A phosphate cytidylyltransferase 1, choline, alpha
PIGC phosphatidylinositol glycan anchor biosynthesis, class C
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PLAU plasminogen activator, urokinase
PLEC plectin
PRDX2 peroxiredoxin 2
PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha
PTHLH parathyroid hormone-like hormone
RAB6A RAB6A, member RAS oncogene family
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RNF17 ring finger protein 17
RPL10L ribosomal protein L10-like
S100A8 S100 calcium binding protein A8
SCAND2P SCAN domain containing 2 pseudogene
SLC48A1 solute carrier family 48 (heme transporter), member 1
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SMAD3 SMAD family member 3
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1
SOGA1 suppressor of glucose, autophagy associated 1
SYNJ1 synaptojanin 1
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
TBCD tubulin folding cofactor D
TBL1Y transducin (beta)-like 1, Y-linked
TBX3 T-box 3
THNSL2 threonine synthase-like 2 (S. cerevisiae)
TMEFF1 transmembrane protein with EGF-like and two follistatin-like domains 1
TMPRSS2 transmembrane protease, serine 2
TNFRSF10C tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TRIM14 tripartite motif containing 14
TRIM36 tripartite motif containing 36
TULP3 tubby like protein 3
UHRF1BP1L UHRF1 binding protein 1-like
VDAC3 voltage-dependent anion channel 3
VIPR1 vasoactive intestinal peptide receptor 1
WSB1 WD repeat and SOCS box containing 1
WWOX WW domain containing oxidoreductase
ZER1 zyg-11 related, cell cycle regulator
ZNF493 zinc finger protein 493
ZNF592 zinc finger protein 592
ZNF609 zinc finger protein 609

decreased expression

Symbol Name
ADAP2 ArfGAP with dual PH domains 2
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent
AP5S1 adaptor-related protein complex 5, sigma 1 subunit
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ARMCX2 armadillo repeat containing, X-linked 2
ATF7IP2 activating transcription factor 7 interacting protein 2
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BCL2A1 BCL2-related protein A1
BMP15 bone morphogenetic protein 15
C10ORF95 chromosome 10 open reading frame 95
C19ORF73 chromosome 19 open reading frame 73
CLDN1 claudin 1
CLEC4E C-type lectin domain family 4, member E
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
COPZ2 coatomer protein complex, subunit zeta 2
CORT cortistatin
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
CYP2B7P cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene
DCAF13 DDB1 and CUL4 associated factor 13
DENND5B DENN/MADD domain containing 5B
DNAJC24 DnaJ (Hsp40) homolog, subfamily C, member 24
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
DYSF dysferlin
EFCAB2 EF-hand calcium binding domain 2
EFHD2 EF-hand domain family, member D2
ERN2 endoplasmic reticulum to nucleus signaling 2
FARP2 FERM, RhoGEF and pleckstrin domain protein 2
FBXO4 F-box protein 4
FER fer (fps/fes related) tyrosine kinase
FGF13 fibroblast growth factor 13
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GALK1 galactokinase 1
GATA4 GATA binding protein 4
GDAP1 ganglioside induced differentiation associated protein 1
GPR157 G protein-coupled receptor 157
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
HCFC2 host cell factor C2
HDAC5 histone deacetylase 5
HIST1H1D histone cluster 1, H1d
HIST1H2BO histone cluster 1, H2bo
HIST1H3G histone cluster 1, H3g
HOXC10 homeobox C10
HOXC5 homeobox C5
HS3ST3A1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
IFI27 interferon, alpha-inducible protein 27
IGFLR1 IGF-like family receptor 1
IL1B interleukin 1, beta
IL4R interleukin 4 receptor
IRF2BP1 interferon regulatory factor 2 binding protein 1
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2
KIAA0754 KIAA0754
LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase
LHX1 LIM homeobox 1
LRRC8E leucine rich repeat containing 8 family, member E
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
MRPL41 mitochondrial ribosomal protein L41
MTHFD2L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like
MYF5 myogenic factor 5
NPIPB15 nuclear pore complex interacting protein family, member B15
PEX26 peroxisomal biogenesis factor 26
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PLCD1 phospholipase C, delta 1
PNKP polynucleotide kinase 3'-phosphatase
POLL polymerase (DNA directed), lambda
POM121 POM121 transmembrane nucleoporin
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
RAB30 RAB30, member RAS oncogene family
RIPK4 receptor-interacting serine-threonine kinase 4
ROM1 retinal outer segment membrane protein 1
RPL13P5 ribosomal protein L13 pseudogene 5
SAA4 serum amyloid A4, constitutive
SAMD9 sterile alpha motif domain containing 9
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
SIGLEC15 sialic acid binding Ig-like lectin 15
SLC25A28 solute carrier family 25 (mitochondrial iron transporter), member 28
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SLC44A1 solute carrier family 44 (choline transporter), member 1
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1
STBD1 starch binding domain 1
STEAP1 six transmembrane epithelial antigen of the prostate 1
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TARP TCR gamma alternate reading frame protein
TCTA T-cell leukemia translocation altered
TMEM104 transmembrane protein 104
TMEM212 transmembrane protein 212
TMSB15A thymosin beta 15a
TPCN1 two pore segment channel 1
TRPV1 transient receptor potential cation channel, subfamily V, member 1
UBTD1 ubiquitin domain containing 1
VASH2 vasohibin 2
WDR91 WD repeat domain 91
ZIC3 Zic family member 3
ZNF134 zinc finger protein 134
ZNRD1-AS1 ZNRD1 antisense RNA 1