khellin-6641 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the khellin-6641 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
AGPAT2 1-acylglycerol-3-phosphate O-acyltransferase 2
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
ATF7IP activating transcription factor 7 interacting protein
ATXN2L ataxin 2-like
BET1L Bet1 golgi vesicular membrane trafficking protein-like
C18ORF25 chromosome 18 open reading frame 25
CADM4 cell adhesion molecule 4
CCDC186 coiled-coil domain containing 186
CDK6 cyclin-dependent kinase 6
CEP295 centrosomal protein 295kDa
CES2 carboxylesterase 2
CHRDL1 chordin-like 1
CLCN4 chloride channel, voltage-sensitive 4
CNGA1 cyclic nucleotide gated channel alpha 1
COBL cordon-bleu WH2 repeat protein
COL1A1 collagen, type I, alpha 1
COL5A1 collagen, type V, alpha 1
CPB1 carboxypeptidase B1 (tissue)
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like
CXCR4 chemokine (C-X-C motif) receptor 4
CYB561 cytochrome b561
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
DDX51 DEAD (Asp-Glu-Ala-Asp) box polypeptide 51
DEDD death effector domain containing
DFNB31 deafness, autosomal recessive 31
DHODH dihydroorotate dehydrogenase (quinone)
DHRS12 dehydrogenase/reductase (SDR family) member 12
DHRS2 dehydrogenase/reductase (SDR family) member 2
DOCK6 dedicator of cytokinesis 6
DUSP10 dual specificity phosphatase 10
ENTPD4 ectonucleoside triphosphate diphosphohydrolase 4
ESR1 estrogen receptor 1
FAIM2 Fas apoptotic inhibitory molecule 2
FCGRT Fc fragment of IgG, receptor, transporter, alpha
FLI1 Fli-1 proto-oncogene, ETS transcription factor
FLJ22184
FLT1 fms-related tyrosine kinase 1
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14
HBE1 hemoglobin, epsilon 1
HOXA11 homeobox A11
IGFBP5 insulin-like growth factor binding protein 5
INCENP inner centromere protein antigens 135/155kDa
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
KCNK12 potassium channel, two pore domain subfamily K, member 12
LIMD1 LIM domains containing 1
LOC157562 uncharacterized LOC157562
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
MAN1C1 mannosidase, alpha, class 1C, member 1
MED18 mediator complex subunit 18
MKL1 megakaryoblastic leukemia (translocation) 1
MMP16 matrix metallopeptidase 16 (membrane-inserted)
MOCS1 molybdenum cofactor synthesis 1
NFIB nuclear factor I/B
NNMT nicotinamide N-methyltransferase
NRF1 nuclear respiratory factor 1
NUMA1 nuclear mitotic apparatus protein 1
OR12D2 olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene)
OR1G1 olfactory receptor, family 1, subfamily G, member 1
PAPPA2 pappalysin 2
PDE4B phosphodiesterase 4B, cAMP-specific
PFDN6 prefoldin subunit 6
PFKFB4 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PKNOX1 PBX/knotted 1 homeobox 1
PLK4 polo-like kinase 4
POMT2 protein-O-mannosyltransferase 2
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PRKG1 protein kinase, cGMP-dependent, type I
PTBP3 polypyrimidine tract binding protein 3
PTPRF protein tyrosine phosphatase, receptor type, F
R3HDM1 R3H domain containing 1
RARG retinoic acid receptor, gamma
RASAL2 RAS protein activator like 2
RGS5 regulator of G-protein signaling 5
RNGTT RNA guanylyltransferase and 5'-phosphatase
RPL35A ribosomal protein L35a
RPS4Y1 ribosomal protein S4, Y-linked 1
SEMA6D sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SLC22A14 solute carrier family 22, member 14
SLC34A2 solute carrier family 34 (type II sodium/phosphate cotransporter), member 2
SPIB Spi-B transcription factor (Spi-1/PU.1 related)
SRSF7 serine/arginine-rich splicing factor 7
SVIL supervillin
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
TBX1 T-box 1
TCP10 t-complex 10
TGFB2 transforming growth factor, beta 2
THOC5 THO complex 5
TLK1 tousled-like kinase 1
TMPO thymopoietin
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TRMT1 tRNA methyltransferase 1 homolog (S. cerevisiae)
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1
UPK1B uroplakin 1B
ZNF276 zinc finger protein 276
ZNF609 zinc finger protein 609

decreased expression

Symbol Name
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ALPK1 alpha-kinase 1
ALS2CL ALS2 C-terminal like
ARMCX4 armadillo repeat containing, X-linked 4
ARSB arylsulfatase B
C17ORF70 chromosome 17 open reading frame 70
C7ORF69 chromosome 7 open reading frame 69
CASP5 caspase 5, apoptosis-related cysteine peptidase
CCDC85C coiled-coil domain containing 85C
CDKL3 cyclin-dependent kinase-like 3
CENPO centromere protein O
CLDN15 claudin 15
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1
CORO2B coronin, actin binding protein, 2B
CST1 cystatin SN
CUZD1 CUB and zona pellucida-like domains 1
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
CXCL3 chemokine (C-X-C motif) ligand 3
DNAH17 dynein, axonemal, heavy chain 17
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
ERN2 endoplasmic reticulum to nucleus signaling 2
F7 coagulation factor VII (serum prothrombin conversion accelerator)
FBRS fibrosin
FBXO40 F-box protein 40
GPR19 G protein-coupled receptor 19
GRAMD1C GRAM domain containing 1C
GRTP1 growth hormone regulated TBC protein 1
H2AFJ H2A histone family, member J
HAMP hepcidin antimicrobial peptide
HHAT hedgehog acyltransferase
HIST1H1D histone cluster 1, H1d
HIST1H2BN histone cluster 1, H2bn
HSPA1L heat shock 70kDa protein 1-like
IGSF6 immunoglobulin superfamily, member 6
IL12B interleukin 12B
IL2 interleukin 2
KDM7A lysine (K)-specific demethylase 7A
KIR2DS1 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1
KLHL4 kelch-like family member 4
KRT20 keratin 20, type I
KRT24 keratin 24, type I
LAMC3 laminin, gamma 3
LINC00341 long intergenic non-protein coding RNA 341
LMCD1 LIM and cysteine-rich domains 1
LOC100287590 uncharacterized LOC100287590
LPAR4 lysophosphatidic acid receptor 4
LTC4S leukotriene C4 synthase
LYRM9 LYR motif containing 9
MDFI MyoD family inhibitor
MEGF8 multiple EGF-like-domains 8
MEIS1 Meis homeobox 1
MGP matrix Gla protein
MICALL2 MICAL-like 2
MMP9 matrix metallopeptidase 9
MNDA myeloid cell nuclear differentiation antigen
NAG18 NAG18 mRNA
NPM3 nucleophosmin/nucleoplasmin 3
PEG3 paternally expressed 3
PLA1A phospholipase A1 member A
PLAG1 pleiomorphic adenoma gene 1
PLEKHO1 pleckstrin homology domain containing, family O member 1
POLL polymerase (DNA directed), lambda
PQLC2 PQ loop repeat containing 2
PRB3 proline-rich protein BstNI subfamily 3
PRF1 perforin 1 (pore forming protein)
QSER1 glutamine and serine rich 1
RAI2 retinoic acid induced 2
RAP1GAP2 RAP1 GTPase activating protein 2
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RNF126P1 ring finger protein 126 pseudogene 1
RNF2 ring finger protein 2
RUNX1-IT1 RUNX1 intronic transcript 1
SAMD9 sterile alpha motif domain containing 9
SAYSD1 SAYSVFN motif domain containing 1
SIX3 SIX homeobox 3
SLC39A1 solute carrier family 39 (zinc transporter), member 1
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2
SMR3A submaxillary gland androgen regulated protein 3A
SPATA1 spermatogenesis associated 1
SPINK5 serine peptidase inhibitor, Kazal type 5
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2)
TMEM212 transmembrane protein 212
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
VNN1 vanin 1
WDR62 WD repeat domain 62
ZAK sterile alpha motif and leucine zipper containing kinase AZK
ZNF10 zinc finger protein 10
ZNF197 zinc finger protein 197
ZNF32 zinc finger protein 32
ZNF37BP zinc finger protein 37B, pseudogene
ZNF415 zinc finger protein 415
ZNF528 zinc finger protein 528
ZNF549 zinc finger protein 549
ZNF639 zinc finger protein 639