khellin Gene Set
Genes
20 genes differentially expressed following the khellin small molecule perturbation from the LINCS L1000 CMAP Chemical Perturbation Consensus Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CASP10
|
caspase 10, apoptosis-related cysteine peptidase
|
4.23467
|
|
ICAM3
|
intercellular adhesion molecule 3
|
3.72773
|
|
TRIM10
|
tripartite motif containing 10
|
3.68913
|
|
UBQLN2
|
ubiquilin 2
|
3.45597
|
|
TSPAN4
|
tetraspanin 4
|
3.45263
|
|
WNT5A
|
wingless-type MMTV integration site family, member 5A
|
3.40773
|
|
TMX2
|
thioredoxin-related transmembrane protein 2
|
3.30875
|
|
DNAJC1
|
DnaJ (Hsp40) homolog, subfamily C, member 1
|
3.13539
|
|
ZMYM2
|
zinc finger, MYM-type 2
|
3.09272
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
EPHB2
|
EPH receptor B2
|
-4.04315
|
|
WASF3
|
WAS protein family, member 3
|
-3.97389
|
|
CKMT2
|
creatine kinase, mitochondrial 2 (sarcomeric)
|
-3.95804
|
|
NR3C1
|
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
|
-3.88643
|
|
RBM34
|
RNA binding motif protein 34
|
-3.58195
|
|
XPNPEP1
|
X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
|
-3.52932
|
|
REPIN1
|
replication initiator 1
|
-3.46809
|
|
CACNG1
|
calcium channel, voltage-dependent, gamma subunit 1
|
-3.45625
|
|
SNRNP27
|
small nuclear ribonucleoprotein 27kDa (U4/U6.U5)
|
-3.36846
|
|
SGK2
|
serum/glucocorticoid regulated kinase 2
|
-3.28749
|
|
ASAP2
|
ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
|
-3.22395
|
