kidney aging Gene Set

Dataset GAD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description disease cluster belonging to disease group aging (Genetic Association Database)
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Genes

98 genes associated with the disease kidney aging in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

Symbol Name
AATF apoptosis antagonizing transcription factor
ACER3 alkaline ceramidase 3
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5
ADCY1 adenylate cyclase 1 (brain)
ADRA2A adrenoceptor alpha 2A
ANTXR1 anthrax toxin receptor 1
ATHL1 ATH1, acid trehalase-like 1 (yeast)
ATP5C1 ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1
ATP5F1 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1
C3 complement component 3
C7 complement component 7
CFB complement factor B
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal)
CLCA1 chloride channel accessory 1
CLIC6 chloride intracellular channel 6
COL15A1 collagen, type XV, alpha 1
COL17A1 collagen, type XVII, alpha 1
COL6A3 collagen, type VI, alpha 3
COX7A2L cytochrome c oxidase subunit VIIa polypeptide 2 like
CXCL14 chemokine (C-X-C motif) ligand 14
DCN decorin
DSPP dentin sialophosphoprotein
ECI2 enoyl-CoA delta isomerase 2
EGF epidermal growth factor
FA2H fatty acid 2-hydroxylase
FBLN2 fibulin 2
FIBIN fin bud initiation factor homolog (zebrafish)
FLRT2 fibronectin leucine rich transmembrane protein 2
FMO5 flavin containing monooxygenase 5
FN1 fibronectin 1
GABRA4 gamma-aminobutyric acid (GABA) A receptor, alpha 4
GABRG2 gamma-aminobutyric acid (GABA) A receptor, gamma 2
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
GLRB glycine receptor, beta
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial
GPC5 glypican 5
GPC6 glypican 6
GPNMB glycoprotein (transmembrane) nmb
GPR61 G protein-coupled receptor 61
HAPLN1 hyaluronan and proteoglycan link protein 1
HIBADH 3-hydroxyisobutyrate dehydrogenase
IGF1R insulin-like growth factor 1 receptor
KERA keratocan
LACC1 laccase (multicopper oxidoreductase) domain containing 1
LAMA3 laminin, alpha 3
LAMB1 laminin, beta 1
LAMC1 laminin, gamma 1 (formerly LAMB2)
LDLRAD4 low density lipoprotein receptor class A domain containing 4
LIX1 Lix1 homolog (chicken)
LPL lipoprotein lipase
LTF lactotransferrin
MAP4 microtubule-associated protein 4
MATN1 matrilin 1, cartilage matrix protein
MATN2 matrilin 2
MFGE8 milk fat globule-EGF factor 8 protein
MMP20 matrix metallopeptidase 20
MMP25 matrix metallopeptidase 25
MMP3 matrix metallopeptidase 3
MMP7 matrix metallopeptidase 7
MMP8 matrix metallopeptidase 8
MMP9 matrix metallopeptidase 9
MPC1 mitochondrial pyruvate carrier 1
MTR 5-methyltetrahydrofolate-homocysteine methyltransferase
NDUFAF1 NADH dehydrogenase (ubiquinone) complex I, assembly factor 1
NDUFC2 NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2, 14.5kDa
NOV nephroblastoma overexpressed
OSMR oncostatin M receptor
PAPPA2 pappalysin 2
PDIA4 protein disulfide isomerase family A, member 4
PEG3 paternally expressed 3
PHYH phytanoyl-CoA 2-hydroxylase
PLK2 polo-like kinase 2
POLR1D polymerase (RNA) I polypeptide D, 16kDa
POSTN periostin, osteoblast specific factor
PRICKLE1 prickle homolog 1 (Drosophila)
PTPRO protein tyrosine phosphatase, receptor type, O
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RFTN1 raftlin, lipid raft linker 1
RGS6 regulator of G-protein signaling 6
RHOBTB3 Rho-related BTB domain containing 3
RPL12 ribosomal protein L12
RPL15 ribosomal protein L15
RPL28 ribosomal protein L28
RPS18 ribosomal protein S18
RPS9 ribosomal protein S9
SACK1F scaffolding CK1 anchoring protein F
SLC16A7 solute carrier family 16 (monocarboxylate transporter), member 7
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SOHLH2 spermatogenesis and oogenesis specific basic helix-loop-helix 2
SP2 Sp2 transcription factor
SPARCL1 SPARC-like 1 (hevin)
SPP1 secreted phosphoprotein 1
TGFB2 transforming growth factor, beta 2
THBS4 thrombospondin 4
TIMP3 TIMP metallopeptidase inhibitor 3
TMEM92 transmembrane protein 92
TPD52 tumor protein D52
TXNDC5 thioredoxin domain containing 5 (endoplasmic reticulum)