kinetin-2511 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the kinetin-2511 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACAN aggrecan
ADAMTS8 ADAM metallopeptidase with thrombospondin type 1 motif, 8
AKR1C4 aldo-keto reductase family 1, member C4
ARMCX4 armadillo repeat containing, X-linked 4
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide
ATP1A3 ATPase, Na+/K+ transporting, alpha 3 polypeptide
ATP5G2 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9)
BCAR3 breast cancer anti-estrogen resistance 3
BIN1 bridging integrator 1
BRSK2 BR serine/threonine kinase 2
C7ORF26 chromosome 7 open reading frame 26
C8A complement component 8, alpha polypeptide
CAMK2A calcium/calmodulin-dependent protein kinase II alpha
CAMK2B calcium/calmodulin-dependent protein kinase II beta
CAMP cathelicidin antimicrobial peptide
CD3D CD3d molecule, delta (CD3-TCR complex)
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CLDN9 claudin 9
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1
COL10A1 collagen, type X, alpha 1
CTNND1 catenin (cadherin-associated protein), delta 1
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
DNAI2 dynein, axonemal, intermediate chain 2
EPHB1 EPH receptor B1
FAM65A family with sequence similarity 65, member A
FGFR4 fibroblast growth factor receptor 4
FLRT3 fibronectin leucine rich transmembrane protein 3
FSTL1 follistatin-like 1
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
GHRH growth hormone releasing hormone
GRB7 growth factor receptor-bound protein 7
GUK1 guanylate kinase 1
HBB hemoglobin, beta
HIST1H2AB histone cluster 1, H2ab
HIST1H2AL histone cluster 1, H2al
HLA-DMA major histocompatibility complex, class II, DM alpha
HTR1F 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled
IBTK inhibitor of Bruton agammaglobulinemia tyrosine kinase
ITGB6 integrin, beta 6
KALRN kalirin, RhoGEF kinase
KCNC1 potassium channel, voltage gated Shaw related subfamily C, member 1
KCNH6 potassium channel, voltage gated eag related subfamily H, member 6
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
KCNMB3 potassium channel subfamily M regulatory beta subunit 3
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1
KIF25 kinesin family member 25
KIR2DL5A killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A
KLF3 Kruppel-like factor 3 (basic)
KRT14 keratin 14, type I
LAD1 ladinin 1
LILRB2 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2
LYPD3 LY6/PLAUR domain containing 3
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
MECOM MDS1 and EVI1 complex locus
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MYL10 myosin, light chain 10, regulatory
NFIB nuclear factor I/B
NOD2 nucleotide-binding oligomerization domain containing 2
OR1G1 olfactory receptor, family 1, subfamily G, member 1
PARP12 poly (ADP-ribose) polymerase family, member 12
PCDHGA1 protocadherin gamma subfamily A, 1
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PKD2L2 polycystic kidney disease 2-like 2
PLD3 phospholipase D family, member 3
PLEKHS1 pleckstrin homology domain containing, family S member 1
PPP1R26 protein phosphatase 1, regulatory subunit 26
PRKACG protein kinase, cAMP-dependent, catalytic, gamma
PRX periaxin
RARG retinoic acid receptor, gamma
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
RBP4 retinol binding protein 4, plasma
RBPMS RNA binding protein with multiple splicing
RGS10 regulator of G-protein signaling 10
RGS11 regulator of G-protein signaling 11
RRAS2 related RAS viral (r-ras) oncogene homolog 2
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein
SLC12A7 solute carrier family 12 (potassium/chloride transporter), member 7
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
SLCO1A2 solute carrier organic anion transporter family, member 1A2
SOX13 SRY (sex determining region Y)-box 13
SPINK5 serine peptidase inhibitor, Kazal type 5
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1
SSX3 synovial sarcoma, X breakpoint 3
SVIL supervillin
TADA3 transcriptional adaptor 3
TAGLN3 transgelin 3
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TCHH trichohyalin
TGFB1 transforming growth factor, beta 1
TLK1 tousled-like kinase 1
TNFRSF4 tumor necrosis factor receptor superfamily, member 4
TRO trophinin
TTLL5 tubulin tyrosine ligase-like family member 5
TTLL7 tubulin tyrosine ligase-like family member 7
UBTD1 ubiquitin domain containing 1
UGT8 UDP glycosyltransferase 8
UMPS uridine monophosphate synthetase
WWTR1 WW domain containing transcription regulator 1

decreased expression

Symbol Name
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3
AGPS alkylglycerone phosphate synthase
ANKHD1 ankyrin repeat and KH domain containing 1
AP1G1 adaptor-related protein complex 1, gamma 1 subunit
ATAD3A ATPase family, AAA domain containing 3A
AUH AU RNA binding protein/enoyl-CoA hydratase
AXIN1 axin 1
B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
BACE1 beta-site APP-cleaving enzyme 1
BMI1 BMI1 proto-oncogene, polycomb ring finger
C8ORF44 chromosome 8 open reading frame 44
CASD1 CAS1 domain containing 1
CCDC88C coiled-coil domain containing 88C
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CDK5 cyclin-dependent kinase 5
CECR1 cat eye syndrome chromosome region, candidate 1
CHML choroideremia-like (Rab escort protein 2)
COPS7B COP9 signalosome subunit 7B
CRYBB2P1 crystallin, beta B2 pseudogene 1
DARS2 aspartyl-tRNA synthetase 2, mitochondrial
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DEF8 differentially expressed in FDCP 8 homolog (mouse)
DEPDC5 DEP domain containing 5
DNAJC1 DnaJ (Hsp40) homolog, subfamily C, member 1
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
EMD emerin
ERF Ets2 repressor factor
ETV4 ets variant 4
EXOC5 exocyst complex component 5
F13A1 coagulation factor XIII, A1 polypeptide
FAM172A family with sequence similarity 172, member A
FANCC Fanconi anemia, complementation group C
FZD2 frizzled class receptor 2
GMEB1 glucocorticoid modulatory element binding protein 1
GMPPA GDP-mannose pyrophosphorylase A
GTF2I general transcription factor IIi
HAUS6 HAUS augmin-like complex, subunit 6
HDHD3 haloacid dehalogenase-like hydrolase domain containing 3
HPSE heparanase
KAT2A K(lysine) acetyltransferase 2A
KCNK5 potassium channel, two pore domain subfamily K, member 5
KIF23 kinesin family member 23
KPNA4 karyopherin alpha 4 (importin alpha 3)
LIN7A lin-7 homolog A (C. elegans)
LMNB1 lamin B1
LPPR3 lipid phosphate phosphatase-related protein type 3
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MAPK3 mitogen-activated protein kinase 3
MBTD1 mbt domain containing 1
METTL16 methyltransferase like 16
MGC12488
MOCOS molybdenum cofactor sulfurase
MOCS3 molybdenum cofactor synthesis 3
MTERF4 mitochondrial transcription termination factor 4
MUM1 melanoma associated antigen (mutated) 1
NAA16 N(alpha)-acetyltransferase 16, NatA auxiliary subunit
NDC1 NDC1 transmembrane nucleoporin
NPL N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase)
NRBF2 nuclear receptor binding factor 2
NTSR1 neurotensin receptor 1 (high affinity)
PCSK7 proprotein convertase subtilisin/kexin type 7
PIAS3 protein inhibitor of activated STAT, 3
POLM polymerase (DNA directed), mu
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PROSER1 proline and serine rich 1
PTS 6-pyruvoyltetrahydropterin synthase
PUS7L pseudouridylate synthase 7 homolog (S. cerevisiae)-like
QDPR quinoid dihydropteridine reductase
RC3H2 ring finger and CCCH-type domains 2
SETD8 SET domain containing (lysine methyltransferase) 8
SHOC2 soc-2 suppressor of clear homolog (C. elegans)
SIDT1 SID1 transmembrane family, member 1
SLC15A3 solute carrier family 15 (oligopeptide transporter), member 3
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
SNIP1 Smad nuclear interacting protein 1
SNX10 sorting nexin 10
SNX16 sorting nexin 16
SOAT1 sterol O-acyltransferase 1
SOHLH2 spermatogenesis and oogenesis specific basic helix-loop-helix 2
SSFA2 sperm specific antigen 2
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TMEM104 transmembrane protein 104
TOPORS topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase
TRABD TraB domain containing
ULK1 unc-51 like autophagy activating kinase 1
UNKL unkempt family zinc finger-like
USB1 U6 snRNA biogenesis 1
VPS54 vacuolar protein sorting 54 homolog (S. cerevisiae)
ZAK sterile alpha motif and leucine zipper containing kinase AZK
ZMAT5 zinc finger, matrin-type 5
ZNF134 zinc finger protein 134
ZNF16 zinc finger protein 16
ZNF304 zinc finger protein 304
ZNF329 zinc finger protein 329
ZNF506 zinc finger protein 506
ZNF767P zinc finger family member 767, pseudogene
ZNF787 zinc finger protein 787
ZNRD1-AS1 ZNRD1 antisense RNA 1