kinetochore Gene Set

Dataset COMPARTMENTS Curated Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A multisubunit complex that is located at the centromeric region of DNA and provides an attachment point for the spindle microtubules. (Gene Ontology, GO_0000776)
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Genes

109 proteins localized to the kinetochore cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
SS18L1 synovial sarcoma translocation gene on chromosome 18-like 1 0.663342
CENPF centromere protein F, 350/400kDa 0.663342
CENPE centromere protein E, 312kDa 0.663342
CENPW centromere protein W 0.663342
CENPV centromere protein V 0.663342
CENPU centromere protein U 0.663342
CENPT centromere protein T 0.663342
SPAG5 sperm associated antigen 5 0.663342
ITGB3BP integrin beta 3 binding protein (beta3-endonexin) 0.663342
KIF2C kinesin family member 2C 0.663342
CENPH centromere protein H 0.663342
CENPI centromere protein I 0.663342
CENPK centromere protein K 0.663342
PSEN2 presenilin 2 0.663342
PSEN1 presenilin 1 0.663342
CLASP2 cytoplasmic linker associated protein 2 0.663342
CLASP1 cytoplasmic linker associated protein 1 0.663342
XPO1 exportin 1 0.663342
TPR translocated promoter region, nuclear basket protein 0.663342
CENPO centromere protein O 0.663342
CENPN centromere protein N 0.663342
CENPM centromere protein M 0.663342
PLK1 polo-like kinase 1 0.663342
SMC1A structural maintenance of chromosomes 1A 0.663342
APITD1 apoptosis-inducing, TAF9-like domain 1 0.663342
CLIP1 CAP-GLY domain containing linker protein 1 0.663342
CENPC centromere protein C 0.663342
CENPA centromere protein A 0.663342
PPP1CC protein phosphatase 1, catalytic subunit, gamma isozyme 0.663342
SPC25 SPC25, NDC80 kinetochore complex component 0.663342
SPC24 SPC24, NDC80 kinetochore complex component 0.663342
HJURP Holliday junction recognition protein 0.663342
NDC80 NDC80 kinetochore complex component 0.663342
NTRK1 neurotrophic tyrosine kinase, receptor, type 1 0.663342
STRA13 stimulated by retinoic acid 13 0.663342
ZNF207 zinc finger protein 207 0.663342
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast) 0.663342
SGOL1 shugoshin-like 1 (S. pombe) 0.663342
ZWILCH zwilch kinetochore protein 0.663342
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B 0.663342
KNSTRN kinetochore-localized astrin/SPAG5 binding protein 0.663342
PMF1 polyamine-modulated factor 1 0.663342
BIRC5 baculoviral IAP repeat containing 5 0.663342
MTBP MDM2 binding protein 0.663342
CHAMP1 chromosome alignment maintaining phosphoprotein 1 0.663342
NUP37 nucleoporin 37kDa 0.663342
PPP1R12A protein phosphatase 1, regulatory subunit 12A 0.663342
NDEL1 nudE neurodevelopment protein 1-like 1 0.663342
KNTC1 kinetochore associated 1 0.663342
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) 0.663342
DYNLL1 dynein, light chain, LC8-type 1 0.663342
SKA2 spindle and kinetochore associated complex subunit 2 0.663342
PINX1 PIN2/TERF1 interacting, telomerase inhibitor 1 0.663342
BUB1 BUB1 mitotic checkpoint serine/threonine kinase 0.663342
BUB3 BUB3 mitotic checkpoint protein 0.663342
MAD2L1P1 MAD2 mitotic arrest deficient-like 1 (yeast) pseudogene 1 0.663342
CASC5 cancer susceptibility candidate 5 0.663342
DCTN1 dynactin 1 0.663342
DCTN2 dynactin 2 (p50) 0.663342
DYNC1I1 dynein, cytoplasmic 1, intermediate chain 1 0.663342
SKA1 spindle and kinetochore associated complex subunit 1 0.663342
SKA3 spindle and kinetochore associated complex subunit 3 0.663342
ZW10 zw10 kinetochore protein 0.663342
NUP107 nucleoporin 107kDa 0.663342
SPDL1 spindle apparatus coiled-coil protein 1 0.663342
NDE1 nudE neurodevelopment protein 1 0.663342
DYNLT3 dynein, light chain, Tctex-type 3 0.663342
AHCTF1 AT hook containing transcription factor 1 0.663342
SEH1L SEH1-like (S. cerevisiae) 0.663342
INCENP inner centromere protein antigens 135/155kDa 0.663342
NEK2 NIMA-related kinase 2 0.663342
NUP85 nucleoporin 85kDa 0.663342
NUP133 nucleoporin 133kDa 0.663342
NUP43 nucleoporin 43kDa 0.663342
CSNK1A1 casein kinase 1, alpha 1 0.663342
DYNC1LI1 dynein, cytoplasmic 1, light intermediate chain 1 0.663342
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) 0.663342
NUF2 NUF2, NDC80 kinetochore complex component 0.663342
ZWINT ZW10 interacting kinetochore protein 0.663342
APC adenomatous polyposis coli 0.663342
ERCC6L excision repair cross-complementation group 6-like 0.663342
NSL1 NSL1, MIS12 kinetochore complex component 0.663342
TP53BP1 tumor protein p53 binding protein 1 0.663342
MIS12 MIS12 kinetochore complex component 0.663342
DSN1 DSN1, MIS12 kinetochore complex component 0.663342
SUMO3 small ubiquitin-like modifier 3 0.237908
SUGT1 SGT1, suppressor of G2 allele of SKP1 (S. cerevisiae) 0.237908
KIF22 kinesin family member 22 0.237908
CCNB1 cyclin B1 0.237908
TEX14 testis expressed 14 0.237908
BOD1 biorientation of chromosomes in cell division 1 0.098109
KIF2B kinesin family member 2B 0.098109
DCTN3 dynactin 3 (p22) 0.098109
DCTN6 dynactin 6 0.098109
RANGAP1 Ran GTPase activating protein 1 0.098109
DCTN5 dynactin 5 (p25) 0.098109
SEPT7 septin 7 0.098109
SEPT6 septin 6 0.098109
SEPT2 septin 2 0.098109
NUDCD2 NudC domain containing 2 0.098109
SGOL2 shugoshin-like 2 (S. pombe) 0.098109
CREBBP CREB binding protein 0.03318
CBX5 chromobox homolog 5 0.03318
ORC2 origin recognition complex, subunit 2 0.03318
PBRM1 polybromo 1 0.03318
KAT8 K(lysine) acetyltransferase 8 0.03318
KAT2B K(lysine) acetyltransferase 2B 0.03318
REC8 REC8 meiotic recombination protein 0.03318
SIN3A SIN3 transcription regulator family member A 0.03318