kit signaling pathway Gene Set

Dataset GO Biological Process Annotations
Category structural or functional annotations
Type biological process
Description A series of molecular signals that starts with the binding of stem cell factor to the tyrosine kinase receptor KIT on the surface of a cell, and ends with regulation of a downstream cellular process, e.g. transcription. Stem cell factor (KIT ligand) binding to the receptor Kit mediates receptor dimerization, activation of its intrinsic tyrosine kinase activity and autophosphorylation. The activated receptor then phosphorylates various substrates, thereby activating distinct signaling cascades within the cell that trigger a change in state or activity of the cell. (Gene Ontology, GO_0038109)
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2 genes participating in the kit signaling pathway biological process from the curated GO Biological Process Annotations dataset.

Symbol Name
FER fer (fps/fes related) tyrosine kinase
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog