klf2 Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description Kruppel-like factor 2|Kruppel-like factors (KLFs) are a family of broadly expressed zinc finger transcription factors. KLF2 regulates T-cell trafficking by promoting expression of the lipid-binding receptor S1P1 (S1PR1; MIM 601974) and the selectin CD62L (SELL; MIM 153240) (summary by Weinreich et al., 2009 [PubMed 19592277]).[supplied by OMIM, Feb 2011] (NCBI Entrez Gene Database, 10365)
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Genes

36 genes co-occuring with the biological term klf2 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ANGPT2 angiopoietin 2
ATF2 activating transcription factor 2
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CXCR4 chemokine (C-X-C motif) receptor 4
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
F2R coagulation factor II (thrombin) receptor
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FOXO1 forkhead box O1
HDAC5 histone deacetylase 5
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HMOX1 heme oxygenase 1
KDR kinase insert domain receptor
KLF1 Kruppel-like factor 1 (erythroid)
KLF13 Kruppel-like factor 13
KLF2 Kruppel-like factor 2
KLF4 Kruppel-like factor 4 (gut)
KLF5 Kruppel-like factor 5 (intestinal)
KLF6 Kruppel-like factor 6
KLF8 Kruppel-like factor 8
LIF leukemia inhibitory factor
LIN28B lin-28 homolog B (C. elegans)
MIR126 microRNA 126
MIR92A1 microRNA 92a-1
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
NFE2L2 nuclear factor, erythroid 2-like 2
NOS3 nitric oxide synthase 3 (endothelial cell)
NUCLEOLIN nucleolin multifunctional protein
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SMURF1 SMAD specific E3 ubiquitin protein ligase 1
THBD thrombomodulin
TP53 tumor protein p53
WEE1 WEE1 G2 checkpoint kinase
WWP1 WW domain containing E3 ubiquitin protein ligase 1
ZFP36 ZFP36 ring finger protein