klf5 Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description Kruppel-like factor 5 (intestinal)|This gene encodes a member of the Kruppel-like factor subfamily of zinc finger proteins. The encoded protein is a transcriptional activator that binds directly to a specific recognition motif in the promoters of target genes. This protein acts downstream of multiple different signaling pathways and is regulated by post-translational modification. It may participate in both promoting and suppressing cell proliferation. Expression of this gene may be changed in a variety of different cancers and in cardiovascular disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2013] (NCBI Entrez Gene Database, 688)
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Genes

39 genes co-occuring with the biological term klf5 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ANP32B acidic (leucine-rich) nuclear phosphoprotein 32 family, member B
AR androgen receptor
BIRC5 baculoviral IAP repeat containing 5
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
CDX1 caudal type homeobox 1
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein)
CXCL12 chemokine (C-X-C motif) ligand 12
CXCR4 chemokine (C-X-C motif) receptor 4
DUSP1 dual specificity phosphatase 1
ESR2 estrogen receptor 2 (ER beta)
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FGFBP1 fibroblast growth factor binding protein 1
GSK3B glycogen synthase kinase 3 beta
HDAC1 histone deacetylase 1
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HK3 hexokinase 3 (white cell)
IL1B interleukin 1, beta
KAT2B K(lysine) acetyltransferase 2B
KLF2 Kruppel-like factor 2
KLF4 Kruppel-like factor 4 (gut)
KLF5 Kruppel-like factor 5 (intestinal)
MMP9 matrix metallopeptidase 9
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYOCD myocardin
NOTCH1 notch 1
PDGFA platelet-derived growth factor alpha polypeptide
PGR progesterone receptor
PTGES prostaglandin E synthase
SALL4 spalt-like transcription factor 4
SMURF2 SMAD specific E3 ubiquitin protein ligase 2
SREBF1 sterol regulatory element binding transcription factor 1
TCF15 transcription factor 15 (basic helix-loop-helix)
TGFB1 transforming growth factor, beta 1
TP53 tumor protein p53
WWP1 WW domain containing E3 ubiquitin protein ligase 1
WWTR1 WW domain containing transcription regulator 1
YAP1 Yes-associated protein 1