klf9_17379758_jejunum_lof_mouse_gpl339_gds2703 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations
Category transcriptomics
Type transcription factor perturbation
Description transcription factor perturbation identified as [TF gene symbol]_[publication PMID]_[cell or tissue]_[perturbation]_[organism]_[GEO platform]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GDS2703
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Genes

336 genes differentially expressed following the klf9_17379758_jejunum_lof_mouse_gpl339_gds2703 transcription factor perturbation from the GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations dataset.

increased expression

Symbol Name Standardized Value
PTGES2 prostaglandin E synthase 2 0.206212
MORF4L1 mortality factor 4 like 1 0.205046
SUDS3 suppressor of defective silencing 3 homolog (S. cerevisiae) 0.198425
BABAM1 BRISC and BRCA1 A complex member 1 0.197543
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1 0.196063
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5 0.195631
SDAD1 SDA1 domain containing 1 0.195542
DNER delta/notch-like EGF repeat containing 0.193834
COLGALT1 collagen beta(1-O)galactosyltransferase 1 0.19373
GALK1 galactokinase 1 0.191002
ALDH1B1 aldehyde dehydrogenase 1 family, member B1 0.190837
CCND2 cyclin D2 0.187398
ALKBH4 alkB, alkylation repair homolog 4 (E. coli) 0.185347
TSPO translocator protein (18kDa) 0.183536
MRPL4 mitochondrial ribosomal protein L4 0.183231
SRF serum response factor (c-fos serum response element-binding transcription factor) 0.181651
NAA10 N(alpha)-acetyltransferase 10, NatA catalytic subunit 0.181424
UBQLN4 ubiquilin 4 0.179935
DDX24 DEAD (Asp-Glu-Ala-Asp) box helicase 24 0.179598
GPR85 G protein-coupled receptor 85 0.176451
PPT2 palmitoyl-protein thioesterase 2 0.174925
SLC25A4 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4 0.172575
TUBB2A tubulin, beta 2A class IIa 0.171412
CLEC3B C-type lectin domain family 3, member B 0.170531
ATAD3A ATPase family, AAA domain containing 3A 0.168679
TMCO4 transmembrane and coiled-coil domains 4 0.168024
NPEPPS aminopeptidase puromycin sensitive 0.161936
MRPL38 mitochondrial ribosomal protein L38 0.160334
COX7A2L cytochrome c oxidase subunit VIIa polypeptide 2 like 0.158893
PRPSAP1 phosphoribosyl pyrophosphate synthetase-associated protein 1 0.15803
HOPX HOP homeobox 0.155733
UNC13A unc-13 homolog A (C. elegans) 0.155356
RPL36 ribosomal protein L36 0.154729
ANAPC7 anaphase promoting complex subunit 7 0.147512
POLDIP2 polymerase (DNA-directed), delta interacting protein 2 0.142484
METAP1 methionyl aminopeptidase 1 0.139081
POLDIP3 polymerase (DNA-directed), delta interacting protein 3 0.136983
SELENBP1 selenium binding protein 1 0.135397
USF2 upstream transcription factor 2, c-fos interacting 0.13442
MAN2C1 mannosidase, alpha, class 2C, member 1 0.131421
EGLN3 egl-9 family hypoxia-inducible factor 3 0.13021
TRAPPC6A trafficking protein particle complex 6A 0.128127
NTN1 netrin 1 0.125716
AFG3L1P AFG3-like AAA ATPase 1, pseudogene 0.124451
EMC10 ER membrane protein complex subunit 10 0.120835
LMO1 LIM domain only 1 (rhombotin 1) 0.120695
NOMO1 NODAL modulator 1 0.115159
LMNA lamin A/C 0.111876
RCCD1 RCC1 domain containing 1 0.110691
CNN3 calponin 3, acidic 0.109709
GRHPR glyoxylate reductase/hydroxypyruvate reductase 0.108147
DGKZ diacylglycerol kinase, zeta 0.103756
MED16 mediator complex subunit 16 0.096333
SRRM4 serine/arginine repetitive matrix 4 0.088414
NDUFB7 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa 0.087957
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain 0.087634
PCOLCE procollagen C-endopeptidase enhancer 0.087501
PHPT1 phosphohistidine phosphatase 1 0.083056
DDB1 damage-specific DNA binding protein 1, 127kDa 0.082388
TRMT1 tRNA methyltransferase 1 homolog (S. cerevisiae) 0.081967
MSLN mesothelin 0.080924
PUF60 poly-U binding splicing factor 60KDa 0.079336
PPP3CB protein phosphatase 3, catalytic subunit, beta isozyme 0.078314
PDLIM1 PDZ and LIM domain 1 0.076665
RAB15 RAB15, member RAS oncogene family 0.076193
NDUFS7 NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase) 0.075408
PPP2R4 protein phosphatase 2A activator, regulatory subunit 4 0.075252
PFKL phosphofructokinase, liver 0.070242
ZNF18 zinc finger protein 18 0.070115
ELAVL4 ELAV like neuron-specific RNA binding protein 4 0.069609
BOLA2 bolA family member 2 0.069427
WDR62 WD repeat domain 62 0.067275
MRPS15 mitochondrial ribosomal protein S15 0.066871
RCE1 Ras converting CAAX endopeptidase 1 0.066412
GDAP1L1 ganglioside induced differentiation associated protein 1-like 1 0.066329
ACAA2 acetyl-CoA acyltransferase 2 0.065067
YKT6 YKT6 v-SNARE homolog (S. cerevisiae) 0.063645
FXYD6 FXYD domain containing ion transport regulator 6 0.063094
SF3B2 splicing factor 3b, subunit 2, 145kDa 0.062544
TCEB2 transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B) 0.060983
PLIN2 perilipin 2 0.060805
EXOC7 exocyst complex component 7 0.057126
AAR2 AAR2 splicing factor homolog (S. cerevisiae) 0.053662
SYNGR2 synaptogyrin 2 0.052928
ALDOA aldolase A, fructose-bisphosphate 0.051437
POFUT1 protein O-fucosyltransferase 1 0.049489
TMEM11 transmembrane protein 11 0.046465
PSMB10 proteasome (prosome, macropain) subunit, beta type, 10 0.043728
CBR3 carbonyl reductase 3 0.040879
ZPBP zona pellucida binding protein 0.039674
FAF1 Fas (TNFRSF6) associated factor 1 0.038449
RAB6B RAB6B, member RAS oncogene family 0.038366
RNF25 ring finger protein 25 0.038089
PPAP2C phosphatidic acid phosphatase type 2C 0.036123
PGD phosphogluconate dehydrogenase 0.032868
SLIT3 slit homolog 3 (Drosophila) 0.032678
DOHH deoxyhypusine hydroxylase/monooxygenase 0.028773
DGUOK deoxyguanosine kinase 0.027893
FAM58BP cyclin-related protein FAM58B 0.0272
SLC4A2 solute carrier family 4 (anion exchanger), member 2 0.026856
NFIC nuclear factor I/C (CCAAT-binding transcription factor) 0.02522
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) 0.023386
CCDC24 coiled-coil domain containing 24 0.020482
HIST1H4B histone cluster 1, H4b 0.017465
SLC12A9 solute carrier family 12, member 9 0.01409
PPP5C protein phosphatase 5, catalytic subunit 0.012967
TINAGL1 tubulointerstitial nephritis antigen-like 1 0.012447
NUDT1 nudix (nucleoside diphosphate linked moiety X)-type motif 1 0.012051
SLC25A39 solute carrier family 25, member 39 0.010819
ANAPC5 anaphase promoting complex subunit 5 0.004911
PGM2 phosphoglucomutase 2 0.004507
TRDN triadin 0.004437
SNAP47 synaptosomal-associated protein, 47kDa 0.001467
SELM selenoprotein M 3.25E-4

decreased expression

Symbol Name Standardized Value
CBS cystathionine-beta-synthase -1.30493
RP2 retinitis pigmentosa 2 (X-linked recessive) -1.30377
CLEC4F C-type lectin domain family 4, member F -1.28335
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta -1.28188
HES5 hes family bHLH transcription factor 5 -1.27018
KRT81 keratin 81, type II -1.26435
PLA2G5 phospholipase A2, group V -1.24864
ZIC5 Zic family member 5 -1.23464
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) -1.20346
APLNR apelin receptor -1.19336
STOM stomatin -1.1906
REPIN1 replication initiator 1 -1.18919
ZKSCAN3 zinc finger with KRAB and SCAN domains 3 -1.18259
SLC26A3 solute carrier family 26 (anion exchanger), member 3 -1.17566
ZNRF2 zinc and ring finger 2, E3 ubiquitin protein ligase -1.17029
DLEU2 deleted in lymphocytic leukemia 2 (non-protein coding) -1.16545
PTK6 protein tyrosine kinase 6 -1.15927
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 -1.15826
STAP1 signal transducing adaptor family member 1 -1.14043
MYO1B myosin IB -1.12105
VAMP4 vesicle-associated membrane protein 4 -1.11069
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid) -1.10711
ATRX alpha thalassemia/mental retardation syndrome X-linked -1.09588
TAX1BP1 Tax1 (human T-cell leukemia virus type I) binding protein 1 -1.07871
USP9X ubiquitin specific peptidase 9, X-linked -1.07149
ZNF276 zinc finger protein 276 -1.0702
HMHA1 histocompatibility (minor) HA-1 -1.06735
FBXO36 F-box protein 36 -1.06416
PVRL3 poliovirus receptor-related 3 -1.05362
PDS5A PDS5 cohesin associated factor A -1.0513
FAM107B family with sequence similarity 107, member B -1.04251
DHX36 DEAH (Asp-Glu-Ala-His) box polypeptide 36 -1.03553
NELL2 NEL-like 2 (chicken) -0.988829
TNRC6A trinucleotide repeat containing 6A -0.987983
DMTF1 cyclin D binding myb-like transcription factor 1 -0.984487
IFNA4 interferon, alpha 4 -0.97093
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha -0.969346
SERTAD2 SERTA domain containing 2 -0.962507
XBP1 X-box binding protein 1 -0.953946
INPP5D inositol polyphosphate-5-phosphatase, 145kDa -0.952894
USP34 ubiquitin specific peptidase 34 -0.923211
IGSF5 immunoglobulin superfamily, member 5 -0.919557
RRBP1 ribosome binding protein 1 -0.918093
LMBR1 limb development membrane protein 1 -0.905838
PPT1 palmitoyl-protein thioesterase 1 -0.901375
SDCBP syndecan binding protein (syntenin) -0.890548
PDXDC1 pyridoxal-dependent decarboxylase domain containing 1 -0.888701
TM9SF2 transmembrane 9 superfamily member 2 -0.880742
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) -0.878919
AKR1E2 aldo-keto reductase family 1, member E2 -0.870881
LCN2 lipocalin 2 -0.868812
ARHGAP29 Rho GTPase activating protein 29 -0.863897
TBC1D8 TBC1 domain family, member 8 (with GRAM domain) -0.83902
TLE4 transducin-like enhancer of split 4 -0.834007
EFCAB14 EF-hand calcium binding domain 14 -0.826205
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1 -0.82465
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1 -0.8241
THOC2 THO complex 2 -0.821657
FGF3 fibroblast growth factor 3 -0.815705
ATXN2 ataxin 2 -0.812513
CCNG1 cyclin G1 -0.80842
ATP6AP2 ATPase, H+ transporting, lysosomal accessory protein 2 -0.802618
SECISBP2L SECIS binding protein 2-like -0.795941
CD38 CD38 molecule -0.789018
CLCN7 chloride channel, voltage-sensitive 7 -0.783534
ZNF442 zinc finger protein 442 -0.783534
LRBA LPS-responsive vesicle trafficking, beach and anchor containing -0.781687
TRAPPC13 trafficking protein particle complex 13 -0.772883
KDM7A lysine (K)-specific demethylase 7A -0.767175
ZFP36L1 ZFP36 ring finger protein-like 1 -0.765793
MALAT1 metastasis associated lung adenocarcinoma transcript 1 (non-protein coding) -0.755968
NET1 neuroepithelial cell transforming 1 -0.753838
SH3BGRL SH3 domain binding glutamate-rich protein like -0.753362
FOXF2 forkhead box F2 -0.748877
PUM2 pumilio RNA-binding family member 2 -0.744607
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium) -0.732579
B3GALT5 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 5 -0.730559
XPO5 exportin 5 -0.724757
CPD carboxypeptidase D -0.716441
CLCA2 chloride channel accessory 2 -0.715726
RNF13 ring finger protein 13 -0.71414
KLF7 Kruppel-like factor 7 (ubiquitous) -0.711773
RAB2A RAB2A, member RAS oncogene family -0.708563
CDK14 cyclin-dependent kinase 14 -0.688481
DAGLB diacylglycerol lipase, beta -0.682266
GCK glucokinase (hexokinase 4) -0.674575
ABCC8 ATP-binding cassette, sub-family C (CFTR/MRP), member 8 -0.671164
DDX46 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 -0.670068
SPTLC2 serine palmitoyltransferase, long chain base subunit 2 -0.666098
ZNF445 zinc finger protein 445 -0.66415
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) -0.664081
CLEC6A C-type lectin domain family 6, member A -0.65818
NSA2 NSA2 ribosome biogenesis homolog (S. cerevisiae) -0.656818
SOCS3 suppressor of cytokine signaling 3 -0.648004
FAM127B family with sequence similarity 127, member B -0.64646
SP3 Sp3 transcription factor -0.644337
TIFA TRAF-interacting protein with forkhead-associated domain -0.640558
GDPD1 glycerophosphodiester phosphodiesterase domain containing 1 -0.638835
DYNLT3 dynein, light chain, Tctex-type 3 -0.6364
PI15 peptidase inhibitor 15 -0.632994
CFI complement factor I -0.631168
SP1 Sp1 transcription factor -0.621353
KIF3B kinesin family member 3B -0.621148
MAGI3 membrane associated guanylate kinase, WW and PDZ domain containing 3 -0.618365
USP43 ubiquitin specific peptidase 43 -0.617359
CEBPG CCAAT/enhancer binding protein (C/EBP), gamma -0.614483
ANKIB1 ankyrin repeat and IBR domain containing 1 -0.614084
CCP110 centriolar coiled coil protein 110kDa -0.613684
UBLCP1 ubiquitin-like domain containing CTD phosphatase 1 -0.610835
TAT tyrosine aminotransferase -0.602333
KIAA1551 KIAA1551 -0.602141
RNF115 ring finger protein 115 -0.595746
DCTN4 dynactin 4 (p62) -0.589791
RAD51D RAD51 paralog D -0.588266
WDR33 WD repeat domain 33 -0.585231
ZBTB8OS zinc finger and BTB domain containing 8 opposite strand -0.584505
MAF1 MAF1 homolog (S. cerevisiae) -0.579613
KSR1 kinase suppressor of ras 1 -0.577072
SNX18 sorting nexin 18 -0.575031
CPSF4L cleavage and polyadenylation specific factor 4-like -0.574742
APAF1 apoptotic peptidase activating factor 1 -0.569441
CLCA1 chloride channel accessory 1 -0.566946
PYHIN1 pyrin and HIN domain family, member 1 -0.562908
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) -0.560806
ZFP64 ZFP64 zinc finger protein -0.560144
MTMR2 myotubularin related protein 2 -0.558055
AKTIP AKT interacting protein -0.552979
SLC5A8 solute carrier family 5 (sodium/monocarboxylate cotransporter), member 8 -0.547323
RDH16 retinol dehydrogenase 16 (all-trans) -0.542461
TMEM30A transmembrane protein 30A -0.541029
BHMT2 betaine--homocysteine S-methyltransferase 2 -0.540416
CLEC4E C-type lectin domain family 4, member E -0.536896
KDM5A lysine (K)-specific demethylase 5A -0.535895
TET1 tet methylcytosine dioxygenase 1 -0.533128
PLAGL1 pleiomorphic adenoma gene-like 1 -0.53
CLTC clathrin, heavy chain (Hc) -0.52932
PDIA3 protein disulfide isomerase family A, member 3 -0.528504
CNTNAP2 contactin associated protein-like 2 -0.527881
SMARCD2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 -0.527451
ETL4 epilepsy, occipitotemporal lobe, and migraine with aura -0.525969
CCNL1 cyclin L1 -0.521918
EHD2 EH-domain containing 2 -0.509865
CRAT carnitine O-acetyltransferase -0.508421
TMEM167A transmembrane protein 167A -0.506474
HAVCR2 hepatitis A virus cellular receptor 2 -0.503686
GLA galactosidase, alpha -0.501535
SENP2 SUMO1/sentrin/SMT3 specific peptidase 2 -0.499606
SLC13A3 solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3 -0.498617
SEC14L1 SEC14-like 1 (S. cerevisiae) -0.49763
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2 -0.496605
GOLM1 golgi membrane protein 1 -0.494093
TDP2 tyrosyl-DNA phosphodiesterase 2 -0.492254
SLCO2A1 solute carrier organic anion transporter family, member 2A1 -0.48844
CXADR coxsackie virus and adenovirus receptor -0.487237
ZNF706 zinc finger protein 706 -0.483467
SBF2 SET binding factor 2 -0.483355
SP4 Sp4 transcription factor -0.48309
RPL7 ribosomal protein L7 -0.482788
BLZF1 basic leucine zipper nuclear factor 1 -0.482412
C19ORF12 chromosome 19 open reading frame 12 -0.479975
DNAJC10 DnaJ (Hsp40) homolog, subfamily C, member 10 -0.477027
NUPR1 nuclear protein, transcriptional regulator, 1 -0.474631
SMAP1 small ArfGAP 1 -0.474561
LDLRAD4 low density lipoprotein receptor class A domain containing 4 -0.473822
JADE1 jade family PHD finger 1 -0.464764
CHN2 chimerin 2 -0.463195
CRYBA1 crystallin, beta A1 -0.463001
CDC42 cell division cycle 42 -0.460232
SLC40A1 solute carrier family 40 (iron-regulated transporter), member 1 -0.458547
KITLG KIT ligand -0.455788
NFKBIZ nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta -0.455219
SUPT16H suppressor of Ty 16 homolog (S. cerevisiae) -0.454025
TRAF3IP2 TRAF3 interacting protein 2 -0.45052
LIME1 Lck interacting transmembrane adaptor 1 -0.450202
UBE4A ubiquitination factor E4A -0.445091
KIAA1033 KIAA1033 -0.444578
DGKQ diacylglycerol kinase, theta 110kDa -0.44412
ATG12 autophagy related 12 -0.440154
LAPTM5 lysosomal protein transmembrane 5 -0.438114
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) -0.436478
KCNA7 potassium channel, voltage gated shaker related subfamily A, member 7 -0.435289
CDK12 cyclin-dependent kinase 12 -0.432487
HARS2 histidyl-tRNA synthetase 2, mitochondrial -0.064639
MFSD6L major facilitator superfamily domain containing 6-like -0.064604
TMEM246 transmembrane protein 246 -0.064392
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase -0.059955
ANKRD54 ankyrin repeat domain 54 -0.056263
SPG7 spastic paraplegia 7 (pure and complicated autosomal recessive) -0.055885
MRPL44 mitochondrial ribosomal protein L44 -0.055349
PSMB4 proteasome (prosome, macropain) subunit, beta type, 4 -0.051713
KRT34 keratin 34, type I -0.051362
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa -0.050788
REEP5 receptor accessory protein 5 -0.049308
TADA3 transcriptional adaptor 3 -0.048969
SRSF9 serine/arginine-rich splicing factor 9 -0.048147
ALDH8A1 aldehyde dehydrogenase 8 family, member A1 -0.047667
MRPL37 mitochondrial ribosomal protein L37 -0.047647
FAM104A family with sequence similarity 104, member A -0.046541
RGS8 regulator of G-protein signaling 8 -0.045912
RANBP17 RAN binding protein 17 -0.045061
NUP62 nucleoporin 62kDa -0.044511
TRIM28 tripartite motif containing 28 -0.041381
TXN2 thioredoxin 2 -0.039066
VAT1 vesicle amine transport 1 -0.032501
MRPL13 mitochondrial ribosomal protein L13 -0.030493
IVD isovaleryl-CoA dehydrogenase -0.028751
IGFBP4 insulin-like growth factor binding protein 4 -0.027548
FAM69B family with sequence similarity 69, member B -0.025107
HK1 hexokinase 1 -0.024665
GNB2 guanine nucleotide binding protein (G protein), beta polypeptide 2 -0.02429
TSPAN17 tetraspanin 17 -0.022738
CDK2AP2 cyclin-dependent kinase 2 associated protein 2 -0.022249
CXXC5 CXXC finger protein 5 -0.018853
PPFIA4 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 -0.018474
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11 -0.017256
TEX261 testis expressed 261 -0.016535
DIAPH1 diaphanous-related formin 1 -0.013821
KIFC2 kinesin family member C2 -0.01232
ADAT2 adenosine deaminase, tRNA-specific 2 -0.009513
AMHR2 anti-Mullerian hormone receptor, type II -0.007085
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha -0.001666
PYGL phosphorylase, glycogen, liver -5.12E-4
Funding