klinefelter's syndrome Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores
Category disease or phenotype associations
Type disease
Description No OMIM mapping, confirmed by DO. [LS]. (Human Disease Ontology, DOID_1921)
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Genes

122 genes co-occuring with the disease klinefelter's syndrome in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) 2.78616
KISS1R KISS1 receptor 2.6007
GNRHR gonadotropin-releasing hormone receptor 2.59453
NR0B1 nuclear receptor subfamily 0, group B, member 1 2.49006
ANOS1 anosmin 1 2.42118
PROKR2 prokineticin receptor 2 2.30811
TAC3 tachykinin 3 2.11534
KISS1 KiSS-1 metastasis-suppressor 2.09383
PROK2 prokineticin 2 2.08221
TACR3 tachykinin receptor 3 2.01614
FGFR1 fibroblast growth factor receptor 1 1.9638
CHD7 chromodomain helicase DNA binding protein 7 1.79165
FGF8 fibroblast growth factor 8 (androgen-induced) 1.73322
NR5A1 nuclear receptor subfamily 5, group A, member 1 1.72274
NSMF NMDA receptor synaptonuclear signaling and neuronal migration factor 1.71362
POLR3A polymerase (RNA) III (DNA directed) polypeptide A, 155kDa 1.68544
POLR3B polymerase (RNA) III (DNA directed) polypeptide B 1.40701
HS6ST1 heparan sulfate 6-O-sulfotransferase 1 1.37381
PROP1 PROP paired-like homeobox 1 1.30488
SHBG sex hormone-binding globulin 1.28523
PRL prolactin 1.26909
GDF6 growth differentiation factor 6 1.25863
TRH thyrotropin-releasing hormone 1.23212
GK glycerol kinase 1.1439
FLRT3 fibronectin leucine rich transmembrane protein 3 1.11477
AMH anti-Mullerian hormone 1.10048
POMC proopiomelanocortin 1.07866
IHH indian hedgehog 1.0732
IGF1 insulin-like growth factor 1 (somatomedin C) 1.01216
LEP leptin 0.994861
AR androgen receptor 0.927105
SRY sex determining region Y 0.90321
INSL3 insulin-like 3 (Leydig cell) 0.879833
IL17RD interleukin 17 receptor D 0.843392
FGF17 fibroblast growth factor 17 0.828639
CXORF21 chromosome X open reading frame 21 0.811001
LEPR leptin receptor 0.803616
LHB luteinizing hormone beta polypeptide 0.788442
SPRY4 sprouty homolog 4 (Drosophila) 0.788033
EBF2 early B-cell factor 2 0.782707
CDY2A chromodomain protein, Y-linked, 2A 0.773705
HESX1 HESX homeobox 1 0.74436
FSHR follicle stimulating hormone receptor 0.743954
RBM28 RNA binding motif protein 28 0.718039
STAR steroidogenic acute regulatory protein 0.711587
LHX3 LIM homeobox 3 0.693098
INS insulin 0.686691
P2RY12 purinergic receptor P2Y, G-protein coupled, 12 0.678701
GHRH growth hormone releasing hormone 0.628457
SHFM1 split hand/foot malformation (ectrodactyly) type 1 0.622183
KRTAP9-3 keratin associated protein 9-3 0.612792
OTUD4 OTU deubiquitinase 4 0.61162
RNF216 ring finger protein 216 0.596012
CDY1B chromodomain protein, Y-linked, 1B 0.595623
OTUD4P1 OTUD4 pseudogene 1 0.592506
PCSK1 proprotein convertase subtilisin/kexin type 1 0.584719
GTPBP6 GTP binding protein 6 (putative) 0.582384
SEMA7A semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group) 0.571107
IL1RAPL1 interleukin 1 receptor accessory protein-like 1 0.5645
RXFP2 relaxin/insulin-like family peptide receptor 2 0.548971
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A 0.541217
DUSP6 dual specificity phosphatase 6 0.535796
XG Xg blood group 0.521888
PLXNC1 plexin C1 0.502675
SOX2 SRY (sex determining region Y)-box 2 0.498085
FSHB follicle stimulating hormone, beta polypeptide 0.493122
DAZ1 deleted in azoospermia 1 0.485885
DAZL deleted in azoospermia-like 0.473361
TBX19 T-box 19 0.454847
LIN28B lin-28 homolog B (C. elegans) 0.448064
DAZ2 deleted in azoospermia 2 0.443547
AIMP1 aminoacyl tRNA synthetase complex-interacting multifunctional protein 1 0.42664
AMELY amelogenin, Y-linked 0.424389
TMOD3 tropomodulin 3 (ubiquitous) 0.418768
FTL ferritin, light polypeptide 0.397471
FTH1 ferritin, heavy polypeptide 1 0.397098
DDX4 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 0.394491
AMELX amelogenin, X-linked 0.393374
VAX1 ventral anterior homeobox 1 0.375179
PDE5A phosphodiesterase 5A, cGMP-specific 0.371477
INTU inturned planar cell polarity protein 0.369258
FGFR2 fibroblast growth factor receptor 2 0.365932
EMX1 empty spiracles homeobox 1 0.357077
CDY1 chromodomain protein, Y-linked, 1 0.344574
FGF1 fibroblast growth factor 1 (acidic) 0.338707
GPR35 G protein-coupled receptor 35 0.32993
GHRL ghrelin/obestatin prepropeptide 0.327375
FGF14 fibroblast growth factor 14 0.324094
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked 0.305948
UTF1 undifferentiated embryonic cell transcription factor 1 0.305587
OTX2 orthodenticle homeobox 2 0.291539
IL3RA interleukin 3 receptor, alpha (low affinity) 0.289744
BGLAP bone gamma-carboxyglutamate (gla) protein 0.283297
HSD3B1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 0.271174
PDYN prodynorphin 0.26266
SYCP3 synaptonemal complex protein 3 0.257711
HFE2 hemochromatosis type 2 (juvenile) 0.257358
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma 0.257005
EFNA3 ephrin-A3 0.249257
CRH corticotropin releasing hormone 0.243645
TECR trans-2,3-enoyl-CoA reductase 0.242245
FEZF1 FEZ family zinc finger 1 0.240148
POU2F1 POU class 2 homeobox 1 0.238054
MIR98 microRNA 98 0.233183
AGO2 argonaute RISC catalytic component 2 0.224196
SIM1 single-minded family bHLH transcription factor 1 0.216332
GALP galanin-like peptide 0.200982
ARRB1 arrestin, beta 1 0.198709
KLRG1 killer cell lectin-like receptor subfamily G, member 1 0.191408
LIN9 lin-9 DREAM MuvB core complex component 0.188326
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) 0.184128
PROK1 prokineticin 1 0.178403
SLC29A3 solute carrier family 29 (equilibrative nucleoside transporter), member 3 0.173314
FGF20 fibroblast growth factor 20 0.171036
INHA inhibin, alpha 0.167452
IGFBP3 insulin-like growth factor binding protein 3 0.163111
EPHA5 EPH receptor A5 0.160203
MC4R melanocortin 4 receptor 0.159658
HAND2 heart and neural crest derivatives expressed 2 0.15948
TFR2 transferrin receptor 2 0.158951
GATA2 GATA binding protein 2 0.158266
KDM5C lysine (K)-specific demethylase 5C 0.157929