| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the labetalol-4473 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACAN | aggrecan |
| ADAM28 | ADAM metallopeptidase domain 28 |
| ADH1B | alcohol dehydrogenase 1B (class I), beta polypeptide |
| AIF1 | allograft inflammatory factor 1 |
| AKR1C2 | aldo-keto reductase family 1, member C2 |
| ALDH6A1 | aldehyde dehydrogenase 6 family, member A1 |
| ALOX5 | arachidonate 5-lipoxygenase |
| ATP2B3 | ATPase, Ca++ transporting, plasma membrane 3 |
| BAZ1B | bromodomain adjacent to zinc finger domain, 1B |
| BTF3P12 | basic transcription factor 3 pseudogene 12 |
| BTNL3 | butyrophilin-like 3 |
| C17ORF53 | chromosome 17 open reading frame 53 |
| C1QB | complement component 1, q subcomponent, B chain |
| C22ORF24 | chromosome 22 open reading frame 24 |
| C5AR1 | complement component 5a receptor 1 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase |
| CCDC121 | coiled-coil domain containing 121 |
| CD52 | CD52 molecule |
| CD86 | CD86 molecule |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) |
| CEACAM7 | carcinoembryonic antigen-related cell adhesion molecule 7 |
| CNKSR2 | connector enhancer of kinase suppressor of Ras 2 |
| CTAGE1 | cutaneous T-cell lymphoma-associated antigen 1 |
| DCN | decorin |
| DUSP10 | dual specificity phosphatase 10 |
| EDAR | ectodysplasin A receptor |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 |
| EPN1 | epsin 1 |
| EPS15L1 | epidermal growth factor receptor pathway substrate 15-like 1 |
| ESR2 | estrogen receptor 2 (ER beta) |
| FLT4 | fms-related tyrosine kinase 4 |
| FYB | FYN binding protein |
| GLI2 | GLI family zinc finger 2 |
| GPR85 | G protein-coupled receptor 85 |
| GRM8 | glutamate receptor, metabotropic 8 |
| GUCA2A | guanylate cyclase activator 2A (guanylin) |
| HAAO | 3-hydroxyanthranilate 3,4-dioxygenase |
| HIST1H3F | histone cluster 1, H3f |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase |
| IFITM1 | interferon induced transmembrane protein 1 |
| IGHM | immunoglobulin heavy constant mu |
| IQCC | IQ motif containing C |
| KCNF1 | potassium channel, voltage gated modifier subfamily F, member 1 |
| KCNIP1 | Kv channel interacting protein 1 |
| KDM5A | lysine (K)-specific demethylase 5A |
| KMO | kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) |
| LAMC3 | laminin, gamma 3 |
| LILRB2 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2 |
| LYL1 | lymphoblastic leukemia associated hematopoiesis regulator 1 |
| MAG | myelin associated glycoprotein |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 |
| MAPK7 | mitogen-activated protein kinase 7 |
| MKL1 | megakaryoblastic leukemia (translocation) 1 |
| MNDA | myeloid cell nuclear differentiation antigen |
| MT1E | metallothionein 1E |
| MT1F | metallothionein 1F |
| MT1M | metallothionein 1M |
| MT1X | metallothionein 1X |
| NNMT | nicotinamide N-methyltransferase |
| NOS1 | nitric oxide synthase 1 (neuronal) |
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 |
| PHOX2A | paired-like homeobox 2a |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| PLXDC1 | plexin domain containing 1 |
| PLXNC1 | plexin C1 |
| POFUT1 | protein O-fucosyltransferase 1 |
| PTHLH | parathyroid hormone-like hormone |
| PTPRH | protein tyrosine phosphatase, receptor type, H |
| RAB11FIP3 | RAB11 family interacting protein 3 (class II) |
| RAD23B | RAD23 homolog B (S. cerevisiae) |
| RBPMS | RNA binding protein with multiple splicing |
| RIMS3 | regulating synaptic membrane exocytosis 3 |
| SAP30 | Sin3A-associated protein, 30kDa |
| SCGB2A2 | secretoglobin, family 2A, member 2 |
| SIX3 | SIX homeobox 3 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 |
| SLC2A9 | solute carrier family 2 (facilitated glucose transporter), member 9 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 |
| SPAG8 | sperm associated antigen 8 |
| SPRR1A | small proline-rich protein 1A |
| SSX1 | synovial sarcoma, X breakpoint 1 |
| STAT2 | signal transducer and activator of transcription 2, 113kDa |
| STEAP4 | STEAP family member 4 |
| STXBP5L | syntaxin binding protein 5-like |
| SULT1B1 | sulfotransferase family, cytosolic, 1B, member 1 |
| TAOK1 | TAO kinase 1 |
| TAPBPL | TAP binding protein-like |
| TCF15 | transcription factor 15 (basic helix-loop-helix) |
| TGFB2 | transforming growth factor, beta 2 |
| TK2 | thymidine kinase 2, mitochondrial |
| TMEM212 | transmembrane protein 212 |
| TNS1 | tensin 1 |
| TSNAXIP1 | translin-associated factor X interacting protein 1 |
| VCX2 | variable charge, X-linked 2 |
| ZHX3 | zinc fingers and homeoboxes 3 |
| ZNF334 | zinc finger protein 334 |
| ZNF391 | zinc finger protein 391 |
| ZNF440 | zinc finger protein 440 |
| Symbol | Name |
|---|---|
| AAAS | achalasia, adrenocortical insufficiency, alacrimia |
| ABHD17B | abhydrolase domain containing 17B |
| ACBD4 | acyl-CoA binding domain containing 4 |
| ADGRB2 | adhesion G protein-coupled receptor B2 |
| AGMAT | agmatine ureohydrolase (agmatinase) |
| ARHGAP10 | Rho GTPase activating protein 10 |
| ARHGEF16 | Rho guanine nucleotide exchange factor (GEF) 16 |
| ATG10 | autophagy related 10 |
| ATPAF2 | ATP synthase mitochondrial F1 complex assembly factor 2 |
| BMP15 | bone morphogenetic protein 15 |
| CA5BP1 | carbonic anhydrase VB pseudogene 1 |
| CBX8 | chromobox homolog 8 |
| CCDC85C | coiled-coil domain containing 85C |
| CD101 | CD101 molecule |
| CD82 | CD82 molecule |
| CES3 | carboxylesterase 3 |
| CIDEC | cell death-inducing DFFA-like effector c |
| CLCN6 | chloride channel, voltage-sensitive 6 |
| CLIC3 | chloride intracellular channel 3 |
| CLN6 | ceroid-lipofuscinosis, neuronal 6, late infantile, variant |
| CPNE7 | copine VII |
| DBNDD1 | dysbindin (dystrobrevin binding protein 1) domain containing 1 |
| DDX31 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 |
| DDX54 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 |
| DOC2A | double C2-like domains, alpha |
| EFNA3 | ephrin-A3 |
| EN1 | engrailed homeobox 1 |
| ENTPD5 | ectonucleoside triphosphate diphosphohydrolase 5 |
| ENTPD7 | ectonucleoside triphosphate diphosphohydrolase 7 |
| EPHX2 | epoxide hydrolase 2, cytoplasmic |
| FBXO2 | F-box protein 2 |
| FKBP5 | FK506 binding protein 5 |
| FRS2 | fibroblast growth factor receptor substrate 2 |
| GAL3ST4 | galactose-3-O-sulfotransferase 4 |
| GDAP2 | ganglioside induced differentiation associated protein 2 |
| GEMIN8 | gem (nuclear organelle) associated protein 8 |
| GINS4 | GINS complex subunit 4 (Sld5 homolog) |
| GMPR | guanosine monophosphate reductase |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HDAC11 | histone deacetylase 11 |
| HIST1H1E | histone cluster 1, H1e |
| HIST1H2AJ | histone cluster 1, H2aj |
| HIST1H3A | histone cluster 1, H3a |
| HLA-DMA | major histocompatibility complex, class II, DM alpha |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 |
| IL17RB | interleukin 17 receptor B |
| INCENP | inner centromere protein antigens 135/155kDa |
| INO80D | INO80 complex subunit D |
| ITGA10 | integrin, alpha 10 |
| KLHL36 | kelch-like family member 36 |
| KLK6 | kallikrein-related peptidase 6 |
| LIMD2 | LIM domain containing 2 |
| LIN7B | lin-7 homolog B (C. elegans) |
| LMO7 | LIM domain 7 |
| LRRC61 | leucine rich repeat containing 61 |
| LTC4S | leukotriene C4 synthase |
| LYRM9 | LYR motif containing 9 |
| MAGEF1 | melanoma antigen family F1 |
| MMP13 | matrix metallopeptidase 13 |
| MOCS3 | molybdenum cofactor synthesis 3 |
| MPI | mannose phosphate isomerase |
| MRM1 | mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) |
| MTA2 | metastasis associated 1 family, member 2 |
| MTERF4 | mitochondrial transcription termination factor 4 |
| MTMR6 | myotubularin related protein 6 |
| NIPSNAP3B | nipsnap homolog 3B (C. elegans) |
| NMB | neuromedin B |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 |
| PCDHGB5 | protocadherin gamma subfamily B, 5 |
| PID1 | phosphotyrosine interaction domain containing 1 |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| POMT2 | protein-O-mannosyltransferase 2 |
| POU3F2 | POU class 3 homeobox 2 |
| RIBC2 | RIB43A domain with coiled-coils 2 |
| RSPH14 | radial spoke head 14 homolog (Chlamydomonas) |
| SEC14L2 | SEC14-like 2 (S. cerevisiae) |
| SH3TC1 | SH3 domain and tetratricopeptide repeats 1 |
| SLC25A21 | solute carrier family 25 (mitochondrial oxoadipate carrier), member 21 |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 |
| SMARCD3 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 |
| SNX16 | sorting nexin 16 |
| SRD5A3 | steroid 5 alpha-reductase 3 |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| SYNGR3 | synaptogyrin 3 |
| TARS2 | threonyl-tRNA synthetase 2, mitochondrial (putative) |
| TBXAS1 | thromboxane A synthase 1 (platelet) |
| TEP1 | telomerase-associated protein 1 |
| TMEM180 | transmembrane protein 180 |
| TPST2 | tyrosylprotein sulfotransferase 2 |
| TRIM25 | tripartite motif containing 25 |
| TRMU | tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase |
| TUBA3C | tubulin, alpha 3c |
| TXLNG | taxilin gamma |
| VN1R1 | vomeronasal 1 receptor 1 |
| ZNF324 | zinc finger protein 324 |
| ZNF480 | zinc finger protein 480 |
| ZNF574 | zinc finger protein 574 |
| ZNF767P | zinc finger family member 767, pseudogene |
| ZNF816 | zinc finger protein 816 |
