| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the labetalol-6809 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AJAP1 | adherens junctions associated protein 1 |
| ARHGEF1 | Rho guanine nucleotide exchange factor (GEF) 1 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 |
| ARNT | aryl hydrocarbon receptor nuclear translocator |
| ASB1 | ankyrin repeat and SOCS box containing 1 |
| B4GALT1 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 |
| BCL2L10 | BCL2-like 10 (apoptosis facilitator) |
| BIN1 | bridging integrator 1 |
| BUD31 | BUD31 homolog (S. cerevisiae) |
| C4BPA | complement component 4 binding protein, alpha |
| C5AR1 | complement component 5a receptor 1 |
| CACNB1 | calcium channel, voltage-dependent, beta 1 subunit |
| CACNG1 | calcium channel, voltage-dependent, gamma subunit 1 |
| CCDC134 | coiled-coil domain containing 134 |
| CD47 | CD47 molecule |
| CD58 | CD58 molecule |
| CDK14 | cyclin-dependent kinase 14 |
| CEL | carboxyl ester lipase |
| CHAT | choline O-acetyltransferase |
| CHRNA6 | cholinergic receptor, nicotinic, alpha 6 (neuronal) |
| CLTC | clathrin, heavy chain (Hc) |
| CST5 | cystatin D |
| CTNS | cystinosin, lysosomal cystine transporter |
| DAPK2 | death-associated protein kinase 2 |
| DIO2 | deiodinase, iodothyronine, type II |
| ENO3 | enolase 3 (beta, muscle) |
| EPB41 | erythrocyte membrane protein band 4.1 |
| GNAS | GNAS complex locus |
| GPR37 | G protein-coupled receptor 37 (endothelin receptor type B-like) |
| GRM1 | glutamate receptor, metabotropic 1 |
| GSK3A | glycogen synthase kinase 3 alpha |
| GSTP1 | glutathione S-transferase pi 1 |
| GUCY1A2 | guanylate cyclase 1, soluble, alpha 2 |
| HLA-DMB | major histocompatibility complex, class II, DM beta |
| HPS4 | Hermansky-Pudlak syndrome 4 |
| IL11 | interleukin 11 |
| IL16 | interleukin 16 |
| IL23A | interleukin 23, alpha subunit p19 |
| ITM2C | integral membrane protein 2C |
| KLHL21 | kelch-like family member 21 |
| KLHL35 | kelch-like family member 35 |
| LOXL2 | lysyl oxidase-like 2 |
| LPCAT4 | lysophosphatidylcholine acyltransferase 4 |
| LY9 | lymphocyte antigen 9 |
| MAPK7 | mitogen-activated protein kinase 7 |
| MAPKBP1 | mitogen-activated protein kinase binding protein 1 |
| MBNL3 | muscleblind-like splicing regulator 3 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase |
| MS4A1 | membrane-spanning 4-domains, subfamily A, member 1 |
| MST1 | macrophage stimulating 1 |
| MT1F | metallothionein 1F |
| MUC3B | mucin 3B, cell surface associated |
| MYL4 | myosin, light chain 4, alkali; atrial, embryonic |
| NFKBIB | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta |
| NPAS2 | neuronal PAS domain protein 2 |
| NPPA | natriuretic peptide A |
| NR1H4 | nuclear receptor subfamily 1, group H, member 4 |
| OR2F1 | olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene) |
| PAPPA2 | pappalysin 2 |
| PDLIM3 | PDZ and LIM domain 3 |
| PKDREJ | polycystin (PKD) family receptor for egg jelly |
| PLD1 | phospholipase D1, phosphatidylcholine-specific |
| PPFIBP2 | PTPRF interacting protein, binding protein 2 (liprin beta 2) |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha |
| PRKG2 | protein kinase, cGMP-dependent, type II |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) |
| PTGS1 | prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) |
| PTHLH | parathyroid hormone-like hormone |
| PURG | purine-rich element binding protein G |
| PYY | peptide YY |
| RAB3B | RAB3B, member RAS oncogene family |
| RIMS3 | regulating synaptic membrane exocytosis 3 |
| RPGRIP1L | RPGRIP1-like |
| RPS3A | ribosomal protein S3A |
| RUNX1 | runt-related transcription factor 1 |
| RYR2 | ryanodine receptor 2 (cardiac) |
| SCLY | selenocysteine lyase |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit |
| SEMA6D | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D |
| SERHL2 | serine hydrolase-like 2 |
| SLC12A8 | solute carrier family 12, member 8 |
| SLC17A7 | solute carrier family 17 (vesicular glutamate transporter), member 7 |
| SLC25A30 | solute carrier family 25, member 30 |
| SLCO1A2 | solute carrier organic anion transporter family, member 1A2 |
| SOX9 | SRY (sex determining region Y)-box 9 |
| SRSF7 | serine/arginine-rich splicing factor 7 |
| ST8SIA3 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3 |
| SULT1B1 | sulfotransferase family, cytosolic, 1B, member 1 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) |
| TMPRSS4 | transmembrane protease, serine 4 |
| TPMT | thiopurine S-methyltransferase |
| UBA7 | ubiquitin-like modifier activating enzyme 7 |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) |
| VAMP2 | vesicle-associated membrane protein 2 (synaptobrevin 2) |
| ZBTB17 | zinc finger and BTB domain containing 17 |
| ZCCHC24 | zinc finger, CCHC domain containing 24 |
| ZNF862 | zinc finger protein 862 |
| Symbol | Name |
|---|---|
| ACAD10 | acyl-CoA dehydrogenase family, member 10 |
| ALPK1 | alpha-kinase 1 |
| ANKZF1 | ankyrin repeat and zinc finger domain containing 1 |
| ANP32A-IT1 | ANP32A intronic transcript 1 |
| ARPIN | actin-related protein 2/3 complex inhibitor |
| ARRB1 | arrestin, beta 1 |
| ATAD5 | ATPase family, AAA domain containing 5 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 |
| BTF3P11 | basic transcription factor 3 pseudogene 11 |
| C22ORF29 | chromosome 22 open reading frame 29 |
| CAMK1 | calcium/calmodulin-dependent protein kinase I |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID |
| CCDC85C | coiled-coil domain containing 85C |
| CENPJ | centromere protein J |
| CGA | glycoprotein hormones, alpha polypeptide |
| CHKB | choline kinase beta |
| CORT | cortistatin |
| CPSF7 | cleavage and polyadenylation specific factor 7, 59kDa |
| CTDP1 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 |
| CXADR | coxsackie virus and adenovirus receptor |
| DGAT1 | diacylglycerol O-acyltransferase 1 |
| DIXDC1 | DIX domain containing 1 |
| DUSP8 | dual specificity phosphatase 8 |
| EFNA3 | ephrin-A3 |
| EGFL7 | EGF-like-domain, multiple 7 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 |
| FAM155B | family with sequence similarity 155, member B |
| FAM63A | family with sequence similarity 63, member A |
| FER | fer (fps/fes related) tyrosine kinase |
| GAMT | guanidinoacetate N-methyltransferase |
| GINS4 | GINS complex subunit 4 (Sld5 homolog) |
| GIT1 | G protein-coupled receptor kinase interacting ArfGAP 1 |
| GNG7 | guanine nucleotide binding protein (G protein), gamma 7 |
| GPATCH3 | G patch domain containing 3 |
| GPR27 | G protein-coupled receptor 27 |
| GSTCD | glutathione S-transferase, C-terminal domain containing |
| GSTTP1 | glutathione S-transferase theta pseudogene 1 |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HDAC7 | histone deacetylase 7 |
| HMHA1 | histocompatibility (minor) HA-1 |
| HMOX1 | heme oxygenase 1 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 |
| IFT54 | intraflagellar transport 54 |
| IL15RA | interleukin 15 receptor, alpha |
| IRF7 | interferon regulatory factor 7 |
| KDM8 | lysine (K)-specific demethylase 8 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) |
| KLHL25 | kelch-like family member 25 |
| LRRC8E | leucine rich repeat containing 8 family, member E |
| LYPLA2P1 | lysophospholipase II pseudogene 1 |
| MAGI1 | membrane associated guanylate kinase, WW and PDZ domain containing 1 |
| MAP1S | microtubule-associated protein 1S |
| MED15 | mediator complex subunit 15 |
| MRPL46 | mitochondrial ribosomal protein L46 |
| MTCP1 | mature T-cell proliferation 1 |
| NCALD | neurocalcin delta |
| NCAM2 | neural cell adhesion molecule 2 |
| NME6 | NME/NM23 nucleoside diphosphate kinase 6 |
| NOL10 | nucleolar protein 10 |
| NRGN | neurogranin (protein kinase C substrate, RC3) |
| NRSN2 | neurensin 2 |
| NXPH4 | neurexophilin 4 |
| PGBD5 | piggyBac transposable element derived 5 |
| PHC1 | polyhomeotic homolog 1 (Drosophila) |
| PIGN | phosphatidylinositol glycan anchor biosynthesis, class N |
| PLA2G4C | phospholipase A2, group IVC (cytosolic, calcium-independent) |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| PLCXD1 | phosphatidylinositol-specific phospholipase C, X domain containing 1 |
| PLEKHB1 | pleckstrin homology domain containing, family B (evectins) member 1 |
| PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
| PRR4 | proline rich 4 (lacrimal) |
| PXN | paxillin |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 |
| RHOBTB2 | Rho-related BTB domain containing 2 |
| SDC3 | syndecan 3 |
| SLC22A18AS | solute carrier family 22 (organic cation transporter), member 18 antisense |
| SMEK2 | SMEK homolog 2, suppressor of mek1 (Dictyostelium) |
| SMIM14 | small integral membrane protein 14 |
| STK11 | serine/threonine kinase 11 |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| TEP1 | telomerase-associated protein 1 |
| THNSL2 | threonine synthase-like 2 (S. cerevisiae) |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TLR5 | toll-like receptor 5 |
| TMSB15A | thymosin beta 15a |
| TRAF6 | TNF receptor-associated factor 6, E3 ubiquitin protein ligase |
| TRIM45 | tripartite motif containing 45 |
| TRPV6 | transient receptor potential cation channel, subfamily V, member 6 |
| USP5 | ubiquitin specific peptidase 5 (isopeptidase T) |
| VWA1 | von Willebrand factor A domain containing 1 |
| WDR19 | WD repeat domain 19 |
| WFDC2 | WAP four-disulfide core domain 2 |
| XPNPEP3 | X-prolyl aminopeptidase 3, mitochondrial |
| ZKSCAN3 | zinc finger with KRAB and SCAN domains 3 |
| ZNF136 | zinc finger protein 136 |
| ZNF205 | zinc finger protein 205 |
| ZNF37BP | zinc finger protein 37B, pseudogene |
| ZNF652 | zinc finger protein 652 |
| ZNF721 | zinc finger protein 721 |
| ZSCAN31 | zinc finger and SCAN domain containing 31 |
