| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the lansoprazole-7306 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ALKBH4 | alkB, alkylation repair homolog 4 (E. coli) |
| ARHGAP26 | Rho GTPase activating protein 26 |
| ARHGAP6 | Rho GTPase activating protein 6 |
| ASTN2 | astrotactin 2 |
| BAZ1B | bromodomain adjacent to zinc finger domain, 1B |
| BTRC | beta-transducin repeat containing E3 ubiquitin protein ligase |
| C16ORF59 | chromosome 16 open reading frame 59 |
| C17ORF70 | chromosome 17 open reading frame 70 |
| C4BPA | complement component 4 binding protein, alpha |
| CA6 | carbonic anhydrase VI |
| CACNG4 | calcium channel, voltage-dependent, gamma subunit 4 |
| CCNO | cyclin O |
| CD6 | CD6 molecule |
| CDC14A | cell division cycle 14A |
| CDK3 | cyclin-dependent kinase 3 |
| CEACAM3 | carcinoembryonic antigen-related cell adhesion molecule 3 |
| CIB2 | calcium and integrin binding family member 2 |
| COL11A2 | collagen, type XI, alpha 2 |
| CPN2 | carboxypeptidase N, polypeptide 2 |
| CTNND2 | catenin (cadherin-associated protein), delta 2 |
| DNAJC17 | DnaJ (Hsp40) homolog, subfamily C, member 17 |
| DSTYK | dual serine/threonine and tyrosine protein kinase |
| DVL3 | dishevelled segment polarity protein 3 |
| DZIP1 | DAZ interacting zinc finger protein 1 |
| EGFR | epidermal growth factor receptor |
| ENTPD1 | ectonucleoside triphosphate diphosphohydrolase 1 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 |
| ERAP1 | endoplasmic reticulum aminopeptidase 1 |
| ESRRG | estrogen-related receptor gamma |
| FARP2 | FERM, RhoGEF and pleckstrin domain protein 2 |
| FBXO21 | F-box protein 21 |
| GAB1 | GRB2-associated binding protein 1 |
| GABRA2 | gamma-aminobutyric acid (GABA) A receptor, alpha 2 |
| GGA2 | golgi-associated, gamma adaptin ear containing, ARF binding protein 2 |
| GGT1 | gamma-glutamyltransferase 1 |
| GPC1 | glypican 1 |
| GPR107 | G protein-coupled receptor 107 |
| GREB1L | growth regulation by estrogen in breast cancer-like |
| HAMP | hepcidin antimicrobial peptide |
| HAP1 | huntingtin-associated protein 1 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 |
| HIST1H1E | histone cluster 1, H1e |
| HLA-DOA | major histocompatibility complex, class II, DO alpha |
| HOMER3 | homer scaffolding protein 3 |
| HOXA4 | homeobox A4 |
| HS3ST2 | heparan sulfate (glucosamine) 3-O-sulfotransferase 2 |
| ID4 | inhibitor of DNA binding 4, dominant negative helix-loop-helix protein |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) |
| ING4 | inhibitor of growth family, member 4 |
| ITGA10 | integrin, alpha 10 |
| ITGB8 | integrin, beta 8 |
| ITIH2 | inter-alpha-trypsin inhibitor heavy chain 2 |
| LARS2 | leucyl-tRNA synthetase 2, mitochondrial |
| LILRB1 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1 |
| LIMK2 | LIM domain kinase 2 |
| LINC00341 | long intergenic non-protein coding RNA 341 |
| LRP1 | low density lipoprotein receptor-related protein 1 |
| LSS | lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) |
| MGAT2 | mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase |
| NAAA | N-acylethanolamine acid amidase |
| NEO1 | neogenin 1 |
| NNMT | nicotinamide N-methyltransferase |
| NRF1 | nuclear respiratory factor 1 |
| NT5M | 5',3'-nucleotidase, mitochondrial |
| OR2H2 | olfactory receptor, family 2, subfamily H, member 2 |
| PDGFB | platelet-derived growth factor beta polypeptide |
| PECAM1 | platelet/endothelial cell adhesion molecule 1 |
| PEX6 | peroxisomal biogenesis factor 6 |
| PIP | prolactin-induced protein |
| PLIN2 | perilipin 2 |
| PPP1R7 | protein phosphatase 1, regulatory subunit 7 |
| PRKCE | protein kinase C, epsilon |
| RIMBP2 | RIMS binding protein 2 |
| RNGTT | RNA guanylyltransferase and 5'-phosphatase |
| RRN3P1 | RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 1 |
| SCN10A | sodium channel, voltage gated, type X alpha subunit |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 |
| SERPINB3 | serpin peptidase inhibitor, clade B (ovalbumin), member 3 |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SH2D2A | SH2 domain containing 2A |
| SMPD2 | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) |
| SNAPC5 | small nuclear RNA activating complex, polypeptide 5, 19kDa |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 |
| SS18 | synovial sarcoma translocation, chromosome 18 |
| STAC | SH3 and cysteine rich domain |
| STS | steroid sulfatase (microsomal), isozyme S |
| TADA2A | transcriptional adaptor 2A |
| TJAP1 | tight junction associated protein 1 (peripheral) |
| TUBA4B | tubulin, alpha 4b |
| UBXN1 | UBX domain protein 1 |
| ULK2 | unc-51 like autophagy activating kinase 2 |
| XYLB | xylulokinase homolog (H. influenzae) |
| ZFYVE9 | zinc finger, FYVE domain containing 9 |
| ZNF609 | zinc finger protein 609 |
| ZNF747 | zinc finger protein 747 |
| ZNF821 | zinc finger protein 821 |
| ZXDB | zinc finger, X-linked, duplicated B |
| Symbol | Name |
|---|---|
| AARSD1 | alanyl-tRNA synthetase domain containing 1 |
| ACOT8 | acyl-CoA thioesterase 8 |
| AHDC1 | AT hook, DNA binding motif, containing 1 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) |
| ALKBH1 | alkB, alkylation repair homolog 1 (E. coli) |
| ANXA10 | annexin A10 |
| ANXA2P3 | annexin A2 pseudogene 3 |
| AP1G2 | adaptor-related protein complex 1, gamma 2 subunit |
| AP4M1 | adaptor-related protein complex 4, mu 1 subunit |
| ATG2A | autophagy related 2A |
| AVEN | apoptosis, caspase activation inhibitor |
| BCOR | BCL6 corepressor |
| BOLA1 | bolA family member 1 |
| C19ORF54 | chromosome 19 open reading frame 54 |
| C3ORF52 | chromosome 3 open reading frame 52 |
| CACTIN | cactin, spliceosome C complex subunit |
| CINP | cyclin-dependent kinase 2 interacting protein |
| COQ4 | coenzyme Q4 |
| CTSD | cathepsin D |
| CYP17A1 | cytochrome P450, family 17, subfamily A, polypeptide 1 |
| DEF6 | differentially expressed in FDCP 6 homolog (mouse) |
| DLK1 | delta-like 1 homolog (Drosophila) |
| ELOVL4 | ELOVL fatty acid elongase 4 |
| ERF | Ets2 repressor factor |
| FAM160B2 | family with sequence similarity 160, member B2 |
| FBXO2 | F-box protein 2 |
| FBXW4 | F-box and WD repeat domain containing 4 |
| FCGRT | Fc fragment of IgG, receptor, transporter, alpha |
| FGD6 | FYVE, RhoGEF and PH domain containing 6 |
| FXN | frataxin |
| GMIP | GEM interacting protein |
| GNAZ | guanine nucleotide binding protein (G protein), alpha z polypeptide |
| GNB1L | guanine nucleotide binding protein (G protein), beta polypeptide 1-like |
| GTF2H4 | general transcription factor IIH, polypeptide 4, 52kDa |
| GUF1 | GUF1 GTPase homolog (S. cerevisiae) |
| HAUS6 | HAUS augmin-like complex, subunit 6 |
| HHLA3 | HERV-H LTR-associating 3 |
| HOXC13 | homeobox C13 |
| HSD3B2 | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 |
| HSPB8 | heat shock 22kDa protein 8 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa |
| INPP5E | inositol polyphosphate-5-phosphatase, 72 kDa |
| IRF2 | interferon regulatory factor 2 |
| KBTBD4 | kelch repeat and BTB (POZ) domain containing 4 |
| KDM5C | lysine (K)-specific demethylase 5C |
| KIAA0894 | KIAA0894 protein |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein |
| LHX6 | LIM homeobox 6 |
| LONRF3 | LON peptidase N-terminal domain and ring finger 3 |
| MAP9 | microtubule-associated protein 9 |
| MBTPS2 | membrane-bound transcription factor peptidase, site 2 |
| METTL2B | methyltransferase like 2B |
| MXD3 | MAX dimerization protein 3 |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase |
| NLK | nemo-like kinase |
| NT5DC3 | 5'-nucleotidase domain containing 3 |
| OLFML2A | olfactomedin-like 2A |
| P3H4 | prolyl 3-hydroxylase family member 4 (non-enzymatic) |
| PAFAH1B2 | platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa) |
| PCK2 | phosphoenolpyruvate carboxykinase 2 (mitochondrial) |
| PCYOX1L | prenylcysteine oxidase 1 like |
| PILRB | paired immunoglobin-like type 2 receptor beta |
| PLEKHO1 | pleckstrin homology domain containing, family O member 1 |
| PPP1R9A | protein phosphatase 1, regulatory subunit 9A |
| PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 |
| PTDSS2 | phosphatidylserine synthase 2 |
| PTGER2 | prostaglandin E receptor 2 (subtype EP2), 53kDa |
| PUS7L | pseudouridylate synthase 7 homolog (S. cerevisiae)-like |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RNF121 | ring finger protein 121 |
| RPUSD2 | RNA pseudouridylate synthase domain containing 2 |
| SAMHD1 | SAM domain and HD domain 1 |
| SERPINB8 | serpin peptidase inhibitor, clade B (ovalbumin), member 8 |
| SLC2A6 | solute carrier family 2 (facilitated glucose transporter), member 6 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 |
| SMEK2 | SMEK homolog 2, suppressor of mek1 (Dictyostelium) |
| SMG9 | SMG9 nonsense mediated mRNA decay factor |
| SMUG1 | single-strand-selective monofunctional uracil-DNA glycosylase 1 |
| SNHG20 | small nucleolar RNA host gene 20 |
| SNX16 | sorting nexin 16 |
| SPAG4 | sperm associated antigen 4 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 |
| SRBD1 | S1 RNA binding domain 1 |
| STAR | steroidogenic acute regulatory protein |
| THBS3 | thrombospondin 3 |
| TKFC | triokinase/FMN cyclase |
| TM7SF2 | transmembrane 7 superfamily member 2 |
| TNNI3 | troponin I type 3 (cardiac) |
| TOMM22 | translocase of outer mitochondrial membrane 22 homolog (yeast) |
| TPST2 | tyrosylprotein sulfotransferase 2 |
| TRAIP | TRAF interacting protein |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein |
| TSPAN1 | tetraspanin 1 |
| USP27X | ubiquitin specific peptidase 27, X-linked |
| USP6 | ubiquitin specific peptidase 6 |
| WDR37 | WD repeat domain 37 |
| XPNPEP3 | X-prolyl aminopeptidase 3, mitochondrial |
| ZBTB44 | zinc finger and BTB domain containing 44 |
| ZNF580 | zinc finger protein 580 |
