lasalocid-3360 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the lasalocid-3360 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADTRP androgen-dependent TFPI-regulating protein
AKR1C1 aldo-keto reductase family 1, member C1
ALDOB aldolase B, fructose-bisphosphate
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
BAIAP3 BAI1-associated protein 3
BCL2L10 BCL2-like 10 (apoptosis facilitator)
BTBD7 BTB (POZ) domain containing 7
C17ORF59 chromosome 17 open reading frame 59
C4BPA complement component 4 binding protein, alpha
CASR calcium-sensing receptor
CDK12 cyclin-dependent kinase 12
CLPS colipase, pancreatic
CTGF connective tissue growth factor
DESI2 desumoylating isopeptidase 2
DNALI1 dynein, axonemal, light intermediate chain 1
DRD2 dopamine receptor D2
DSC3 desmocollin 3
EGR1 early growth response 1
EGR3 early growth response 3
EHMT1 euchromatic histone-lysine N-methyltransferase 1
ELP6 elongator acetyltransferase complex subunit 6
ERC2-IT1 ERC2 intronic transcript 1
FBLN1 fibulin 1
FCMR Fc fragment of IgM receptor
FGF5 fibroblast growth factor 5
FRMD1 FERM domain containing 1
FRMD4B FERM domain containing 4B
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2
GLS glutaminase
GPR161 G protein-coupled receptor 161
HIST1H4A histone cluster 1, H4a
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HNF4A hepatocyte nuclear factor 4, alpha
HOXB3 homeobox B3
HP haptoglobin
IL2RB interleukin 2 receptor, beta
INPP5B inositol polyphosphate-5-phosphatase, 75kDa
IRS4 insulin receptor substrate 4
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KDM8 lysine (K)-specific demethylase 8
KIAA1109 KIAA1109
KRT16 keratin 16, type I
LDLRAD4 low density lipoprotein receptor class A domain containing 4
LIMD1 LIM domains containing 1
LIN7A lin-7 homolog A (C. elegans)
LRCH4 leucine-rich repeats and calponin homology (CH) domain containing 4
LRRC75B leucine rich repeat containing 75B
LRRC8B leucine rich repeat containing 8 family, member B
LTBP4 latent transforming growth factor beta binding protein 4
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MBNL2 muscleblind-like splicing regulator 2
MCOLN1 mucolipin 1
MST1R macrophage stimulating 1 receptor
NAB1 NGFI-A binding protein 1 (EGR1 binding protein 1)
NAT6 N-acetyltransferase 6 (GCN5-related)
NDOR1 NADPH dependent diflavin oxidoreductase 1
NR2F1 nuclear receptor subfamily 2, group F, member 1
OBSL1 obscurin-like 1
ONECUT2 one cut homeobox 2
OR2B6 olfactory receptor, family 2, subfamily B, member 6
PER1 period circadian clock 1
PIN1P1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 pseudogene 1
PLA2G3 phospholipase A2, group III
PLCE1 phospholipase C, epsilon 1
PMS2P3 postmeiotic segregation increased 2 pseudogene 3
POMT2 protein-O-mannosyltransferase 2
PPP1R1A protein phosphatase 1, regulatory (inhibitor) subunit 1A
PQLC2 PQ loop repeat containing 2
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PRSS53 protease, serine, 53
RAD52 RAD52 homolog (S. cerevisiae)
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RGS2 regulator of G-protein signaling 2
S100A9 S100 calcium binding protein A9
SFI1 Sfi1 homolog, spindle assembly associated (yeast)
SLC6A9 solute carrier family 6 (neurotransmitter transporter, glycine), member 9
SNAPC5 small nuclear RNA activating complex, polypeptide 5, 19kDa
SPRR2B small proline-rich protein 2B
STAB2 stabilin 2
STMN3 stathmin-like 3
T T, brachyury homolog (mouse)
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
TBX3 T-box 3
TDRKH tudor and KH domain containing
TMOD1 tropomodulin 1
TMPRSS6 transmembrane protease, serine 6
TNKS tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
TNNI3 troponin I type 3 (cardiac)
TPP1 tripeptidyl peptidase I
TRIL TLR4 interactor with leucine-rich repeats
TRIM68 tripartite motif containing 68
TTC38 tetratricopeptide repeat domain 38
WDFY3 WD repeat and FYVE domain containing 3
WIPF1 WAS/WASL interacting protein family, member 1
ZDHHC8P1 zinc finger, DHHC-type containing 8 pseudogene 1
ZNF589 zinc finger protein 589
ZZEF1 zinc finger, ZZ-type with EF-hand domain 1

decreased expression

Symbol Name
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ACTL8 actin-like 8
ADAP2 ArfGAP with dual PH domains 2
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C
ARC activity-regulated cytoskeleton-associated protein
ARRB1 arrestin, beta 1
ATF7 activating transcription factor 7
BMP10 bone morphogenetic protein 10
C1ORF105 chromosome 1 open reading frame 105
C8ORF44 chromosome 8 open reading frame 44
C8ORF60 chromosome 8 open reading frame 60
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CCDC85C coiled-coil domain containing 85C
CD82 CD82 molecule
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CDH10 cadherin 10, type 2 (T2-cadherin)
CHML choroideremia-like (Rab escort protein 2)
CLCN2 chloride channel, voltage-sensitive 2
CLDN1 claudin 1
CNTN1 contactin 1
CSTA cystatin A (stefin A)
CYP2B7P cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
DAGLA diacylglycerol lipase, alpha
DCBLD2 discoidin, CUB and LCCL domain containing 2
DNAH17 dynein, axonemal, heavy chain 17
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
ERN2 endoplasmic reticulum to nucleus signaling 2
EXD3 exonuclease 3'-5' domain containing 3
FBXL7 F-box and leucine-rich repeat protein 7
FOXN2 forkhead box N2
FSD1 fibronectin type III and SPRY domain containing 1
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
GFI1 growth factor independent 1 transcription repressor
GPR15 G protein-coupled receptor 15
GPR27 G protein-coupled receptor 27
GPR68 G protein-coupled receptor 68
GPR85 G protein-coupled receptor 85
HDAC11 histone deacetylase 11
HIST1H2AL histone cluster 1, H2al
HLA-DMB major histocompatibility complex, class II, DM beta
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2
KLC2 kinesin light chain 2
KRT31 keratin 31, type I
LY6G6C lymphocyte antigen 6 complex, locus G6C
MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2
MFI2 antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5
MFSD6 major facilitator superfamily domain containing 6
MRPL41 mitochondrial ribosomal protein L41
MTA2 metastasis associated 1 family, member 2
MYOZ3 myozenin 3
NDE1 nudE neurodevelopment protein 1
NIPAL2 NIPA-like domain containing 2
OR12D2 olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene)
PCDHGA10 protocadherin gamma subfamily A, 10
PLEKHO2 pleckstrin homology domain containing, family O member 2
PPP2R3B protein phosphatase 2, regulatory subunit B'', beta
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
PURG purine-rich element binding protein G
QPCT glutaminyl-peptide cyclotransferase
RNF122 ring finger protein 122
RPL10L ribosomal protein L10-like
RPS4Y1 ribosomal protein S4, Y-linked 1
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1
SCGB2A2 secretoglobin, family 2A, member 2
SEMA7A semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SKI SKI proto-oncogene
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
SLIT2 slit homolog 2 (Drosophila)
SND1-IT1 SND1 intronic transcript 1
SPTBN2 spectrin, beta, non-erythrocytic 2
STIM1 stromal interaction molecule 1
SULT4A1 sulfotransferase family 4A, member 1
SYCP2 synaptonemal complex protein 2
SYNDIG1 synapse differentiation inducing 1
TCP10 t-complex 10
THRB thyroid hormone receptor, beta
TM4SF5 transmembrane 4 L six family member 5
TMEM209 transmembrane protein 209
TMEM212 transmembrane protein 212
TMEM8B transmembrane protein 8B
TONSL tonsoku-like, DNA repair protein
TOR4A torsin family 4, member A
TRIM36 tripartite motif containing 36
TRPV4 transient receptor potential cation channel, subfamily V, member 4
TSGA10 testis specific, 10
USB1 U6 snRNA biogenesis 1
WDR91 WD repeat domain 91
ZIC3 Zic family member 3
ZIM2 zinc finger, imprinted 2
ZNF197 zinc finger protein 197
ZNF205 zinc finger protein 205
ZNF573 zinc finger protein 573
ZNF639 zinc finger protein 639