| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the lasalocid-4985 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADRBK1 | adrenergic, beta, receptor kinase 1 |
| AQP3 | aquaporin 3 (Gill blood group) |
| AREG | amphiregulin |
| ARFGAP3 | ADP-ribosylation factor GTPase activating protein 3 |
| ASPH | aspartate beta-hydroxylase |
| B9D1 | B9 protein domain 1 |
| BCL6 | B-cell CLL/lymphoma 6 |
| BHLHE40 | basic helix-loop-helix family, member e40 |
| BIRC3 | baculoviral IAP repeat containing 3 |
| BMP4 | bone morphogenetic protein 4 |
| CACNB2 | calcium channel, voltage-dependent, beta 2 subunit |
| CAMK1 | calcium/calmodulin-dependent protein kinase I |
| CCNG2 | cyclin G2 |
| CCNO | cyclin O |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CHRNB1 | cholinergic receptor, nicotinic, beta 1 (muscle) |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 |
| CLCN7 | chloride channel, voltage-sensitive 7 |
| CLDN4 | claudin 4 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DHCR7 | 7-dehydrocholesterol reductase |
| DUSP4 | dual specificity phosphatase 4 |
| DUSP5 | dual specificity phosphatase 5 |
| DUSP6 | dual specificity phosphatase 6 |
| ECE1 | endothelin converting enzyme 1 |
| EDAR | ectodysplasin A receptor |
| EGR1 | early growth response 1 |
| EGR3 | early growth response 3 |
| EMP1 | epithelial membrane protein 1 |
| EPAS1 | endothelial PAS domain protein 1 |
| EPHA2 | EPH receptor A2 |
| ETV5 | ets variant 5 |
| FAM114A1 | family with sequence similarity 114, member A1 |
| FAM174B | family with sequence similarity 174, member B |
| FCMR | Fc fragment of IgM receptor |
| FUT6 | fucosyltransferase 6 (alpha (1,3) fucosyltransferase) |
| GAMT | guanidinoacetate N-methyltransferase |
| GOLGA2 | golgin A2 |
| GSPT1 | G1 to S phase transition 1 |
| HDLBP | high density lipoprotein binding protein |
| HEG1 | heart development protein with EGF-like domains 1 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 |
| HMGCR | 3-hydroxy-3-methylglutaryl-CoA reductase |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
| HOXD11 | homeobox D11 |
| INSIG1 | insulin induced gene 1 |
| ISG20 | interferon stimulated exonuclease gene 20kDa |
| ITGA6 | integrin, alpha 6 |
| JUND | jun D proto-oncogene |
| KDELR3 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 |
| KLF6 | Kruppel-like factor 6 |
| KLHL24 | kelch-like family member 24 |
| KRT19P2 | keratin 19 pseudogene 2 |
| LARP6 | La ribonucleoprotein domain family, member 6 |
| LDLR | low density lipoprotein receptor |
| LIF | leukemia inhibitory factor |
| LPIN1 | lipin 1 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MALL | mal, T-cell differentiation protein-like |
| MSMO1 | methylsterol monooxygenase 1 |
| NADK | NAD kinase |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase |
| NEU1 | sialidase 1 (lysosomal sialidase) |
| NFKBIB | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta |
| NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
| NME5 | NME/NM23 family member 5 |
| NPM3 | nucleophosmin/nucleoplasmin 3 |
| PBXIP1 | pre-B-cell leukemia homeobox interacting protein 1 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
| PIN1 | peptidylprolyl cis/trans isomerase, NIMA-interacting 1 |
| PLAU | plasminogen activator, urokinase |
| PLAUR | plasminogen activator, urokinase receptor |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 |
| PRSS22 | protease, serine, 22 |
| PTPN22 | protein tyrosine phosphatase, non-receptor type 22 (lymphoid) |
| RPS2 | ribosomal protein S2 |
| SEC14L1 | SEC14-like 1 (S. cerevisiae) |
| SEC24D | SEC24 family member D |
| SLC17A5 | solute carrier family 17 (acidic sugar transporter), member 5 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SLCO4C1 | solute carrier organic anion transporter family, member 4C1 |
| SMAD3 | SMAD family member 3 |
| SMOX | spermine oxidase |
| SOX9 | SRY (sex determining region Y)-box 9 |
| SPRY4 | sprouty homolog 4 (Drosophila) |
| SQLE | squalene epoxidase |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 |
| STX5 | syntaxin 5 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 |
| TMPRSS2 | transmembrane protease, serine 2 |
| TNFAIP1 | tumor necrosis factor, alpha-induced protein 1 (endothelial) |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 |
| TRIM2 | tripartite motif containing 2 |
| TRIM29 | tripartite motif containing 29 |
| TRPV6 | transient receptor potential cation channel, subfamily V, member 6 |
| WIPI1 | WD repeat domain, phosphoinositide interacting 1 |
| YIF1B | Yip1 interacting factor homolog B (S. cerevisiae) |
| ZNF446 | zinc finger protein 446 |
| Symbol | Name |
|---|---|
| ALOX15 | arachidonate 15-lipoxygenase |
| ALPK1 | alpha-kinase 1 |
| ANKFY1 | ankyrin repeat and FYVE domain containing 1 |
| ARID3B | AT rich interactive domain 3B (BRIGHT-like) |
| ATG16L1 | autophagy related 16-like 1 (S. cerevisiae) |
| BCL11B | B-cell CLL/lymphoma 11B (zinc finger protein) |
| C21ORF91 | chromosome 21 open reading frame 91 |
| C2ORF54 | chromosome 2 open reading frame 54 |
| C5AR2 | complement component 5a receptor 2 |
| C5ORF45 | chromosome 5 open reading frame 45 |
| CARD8 | caspase recruitment domain family, member 8 |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha |
| CEP97 | centrosomal protein 97kDa |
| CIDEC | cell death-inducing DFFA-like effector c |
| CYP17A1 | cytochrome P450, family 17, subfamily A, polypeptide 1 |
| DHX35 | DEAH (Asp-Glu-Ala-His) box polypeptide 35 |
| DOC2A | double C2-like domains, alpha |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 |
| EHHADH | enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase |
| EPB41L5 | erythrocyte membrane protein band 4.1 like 5 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FAM155A | family with sequence similarity 155, member A |
| FBRS | fibrosin |
| FBXL2 | F-box and leucine-rich repeat protein 2 |
| FGD1 | FYVE, RhoGEF and PH domain containing 1 |
| FLT4 | fms-related tyrosine kinase 4 |
| FOXN2 | forkhead box N2 |
| GALNT12 | polypeptide N-acetylgalactosaminyltransferase 12 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 |
| GHR | growth hormone receptor |
| GINS4 | GINS complex subunit 4 (Sld5 homolog) |
| GIT1 | G protein-coupled receptor kinase interacting ArfGAP 1 |
| GPR157 | G protein-coupled receptor 157 |
| GPR19 | G protein-coupled receptor 19 |
| GRTP1 | growth hormone regulated TBC protein 1 |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HIST1H2AL | histone cluster 1, H2al |
| HIST1H2BO | histone cluster 1, H2bo |
| HOXC10 | homeobox C10 |
| HTR1E | 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein |
| IL17RB | interleukin 17 receptor B |
| IRAK4 | interleukin-1 receptor-associated kinase 4 |
| ITPKB | inositol-trisphosphate 3-kinase B |
| KCTD7 | potassium channel tetramerization domain containing 7 |
| KIAA0125 | KIAA0125 |
| LIN7B | lin-7 homolog B (C. elegans) |
| LMO2 | LIM domain only 2 (rhombotin-like 1) |
| LNPEP | leucyl/cystinyl aminopeptidase |
| MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B |
| NAP1L2 | nucleosome assembly protein 1-like 2 |
| NDE1 | nudE neurodevelopment protein 1 |
| NDUFAF5 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 5 |
| PHF21A | PHD finger protein 21A |
| PLD2 | phospholipase D2 |
| PLEKHA6 | pleckstrin homology domain containing, family A member 6 |
| PPP1R9A | protein phosphatase 1, regulatory subunit 9A |
| PRKCD | protein kinase C, delta |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 |
| PVRL3 | poliovirus receptor-related 3 |
| RCBTB2 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 |
| RGS20 | regulator of G-protein signaling 20 |
| RIBC2 | RIB43A domain with coiled-coils 2 |
| RLN1 | relaxin 1 |
| RNF125 | ring finger protein 125, E3 ubiquitin protein ligase |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| ROBO3 | roundabout, axon guidance receptor, homolog 3 (Drosophila) |
| ROM1 | retinal outer segment membrane protein 1 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A |
| SLC8B1 | solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 |
| SLIT2 | slit homolog 2 (Drosophila) |
| SMPD2 | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) |
| SP140L | SP140 nuclear body protein-like |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 |
| STEAP1 | six transmembrane epithelial antigen of the prostate 1 |
| STX1A | syntaxin 1A (brain) |
| SUSD4 | sushi domain containing 4 |
| TAB1 | TGF-beta activated kinase 1/MAP3K7 binding protein 1 |
| TBX19 | T-box 19 |
| TCTA | T-cell leukemia translocation altered |
| THRAP3 | thyroid hormone receptor associated protein 3 |
| TMEM180 | transmembrane protein 180 |
| TMEM184C | transmembrane protein 184C |
| TMEM242 | transmembrane protein 242 |
| TPK1 | thiamin pyrophosphokinase 1 |
| TRIM21 | tripartite motif containing 21 |
| TRMT12 | tRNA methyltransferase 12 homolog (S. cerevisiae) |
| UCN | urocortin |
| USB1 | U6 snRNA biogenesis 1 |
| WDR76 | WD repeat domain 76 |
| XYLT2 | xylosyltransferase II |
| ZMYM3 | zinc finger, MYM-type 3 |
| ZNF204P | zinc finger protein 204, pseudogene |
| ZNF37BP | zinc finger protein 37B, pseudogene |
| ZNF611 | zinc finger protein 611 |
| ZNF778 | zinc finger protein 778 |
| ZNF813 | zinc finger protein 813 |
| ZNF862 | zinc finger protein 862 |
| ZSCAN26 | zinc finger and SCAN domain containing 26 |
