lasalocid-6639 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

194 genes differentially expressed following the lasalocid-6639 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A1CF APOBEC1 complementation factor
ADAM23 ADAM metallopeptidase domain 23
ATF3 activating transcription factor 3
BAGE B melanoma antigen
BIRC3 baculoviral IAP repeat containing 3
BTF3P11 basic transcription factor 3 pseudogene 11
C14ORF1 chromosome 14 open reading frame 1
C1ORF54 chromosome 1 open reading frame 54
C8A complement component 8, alpha polypeptide
CCKAR cholecystokinin A receptor
CDC14B cell division cycle 14B
CDR2 cerebellar degeneration-related protein 2, 62kDa
CEACAM3 carcinoembryonic antigen-related cell adhesion molecule 3
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CXCL2 chemokine (C-X-C motif) ligand 2
CXCL3 chemokine (C-X-C motif) ligand 3
CXCR4 chemokine (C-X-C motif) receptor 4
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DHRS9 dehydrogenase/reductase (SDR family) member 9
DIAPH2-AS1 DIAPH2 antisense RNA 1
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
DOCK6 dedicator of cytokinesis 6
DVL2 dishevelled segment polarity protein 2
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3
EMX1 empty spiracles homeobox 1
ENPEP glutamyl aminopeptidase (aminopeptidase A)
ENTPD4 ectonucleoside triphosphate diphosphohydrolase 4
FGF1 fibroblast growth factor 1 (acidic)
FGF4 fibroblast growth factor 4
FLT3LG fms-related tyrosine kinase 3 ligand
FRMD4B FERM domain containing 4B
FYB FYN binding protein
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class)
GSTM5 glutathione S-transferase mu 5
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
ICAM1 intercellular adhesion molecule 1
IGHA1 immunoglobulin heavy constant alpha 1
ING2 inhibitor of growth family, member 2
INSIG1 insulin induced gene 1
JUN jun proto-oncogene
JUND jun D proto-oncogene
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1
KCNB1 potassium channel, voltage gated Shab related subfamily B, member 1
KMO kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
KRT34 keratin 34, type I
LDHC lactate dehydrogenase C
LIF leukemia inhibitory factor
LIMD1 LIM domains containing 1
LLGL1 lethal giant larvae homolog 1 (Drosophila)
LOC202181 SUMO-interacting motifs containing 1 pseudogene
LOX lysyl oxidase
MAPK14 mitogen-activated protein kinase 14
MPZ myelin protein zero
NEK11 NIMA-related kinase 11
NPAS1 neuronal PAS domain protein 1
NPC1 Niemann-Pick disease, type C1
OR1D2 olfactory receptor, family 1, subfamily D, member 2
PARP6 poly (ADP-ribose) polymerase family, member 6
PCDHB17P protocadherin beta 17 pseudogene
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PIN1P1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 pseudogene 1
PLBD1 phospholipase B domain containing 1
PLK4 polo-like kinase 4
POMT2 protein-O-mannosyltransferase 2
PPP1R15A protein phosphatase 1, regulatory subunit 15A
PROL1 proline rich, lacrimal 1
PTPRD protein tyrosine phosphatase, receptor type, D
PYY peptide YY
RGS4 regulator of G-protein signaling 4
RPL10L ribosomal protein L10-like
RPL35A ribosomal protein L35a
RTCA RNA 3'-terminal phosphate cyclase
RUNDC3A RUN domain containing 3A
RUNX1 runt-related transcription factor 1
SAMD4A sterile alpha motif domain containing 4A
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37
SNN stannin
SPRED2 sprouty-related, EVH1 domain containing 2
SQLE squalene epoxidase
SQSTM1 sequestosome 1
STS steroid sulfatase (microsomal), isozyme S
SWAP70 SWAP switching B-cell complex 70kDa subunit
TGFA transforming growth factor, alpha
THOC5 THO complex 5
THPO thrombopoietin
TIMELESS timeless circadian clock
TLK1 tousled-like kinase 1
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TRIB3 tribbles pseudokinase 3
TUBA3C tubulin, alpha 3c
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1
UBE2B ubiquitin-conjugating enzyme E2B
UTS2 urotensin 2
VAX2 ventral anterior homeobox 2
WNT8B wingless-type MMTV integration site family, member 8B
XBP1 X-box binding protein 1
ZNF165 zinc finger protein 165

decreased expression

Symbol Name
ALOX12P2 arachidonate 12-lipoxygenase pseudogene 2
ANXA2P1 annexin A2 pseudogene 1
ARR3 arrestin 3, retinal (X-arrestin)
ARSB arylsulfatase B
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
C14ORF79 chromosome 14 open reading frame 79
C4ORF19 chromosome 4 open reading frame 19
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2
CCDC85C coiled-coil domain containing 85C
CCNO cyclin O
CES3 carboxylesterase 3
CFAP45 cilia and flagella associated protein 45
CHMP6 charged multivesicular body protein 6
CNGA1 cyclic nucleotide gated channel alpha 1
CNN2 calponin 2
COL9A2 collagen, type IX, alpha 2
CUZD1 CUB and zona pellucida-like domains 1
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
CYBRD1 cytochrome b reductase 1
CYP2B7P cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene
CYP2J2 cytochrome P450, family 2, subfamily J, polypeptide 2
CYP4F8 cytochrome P450, family 4, subfamily F, polypeptide 8
DBF4B DBF4 zinc finger B
DDN dendrin
DEF6 differentially expressed in FDCP 6 homolog (mouse)
DLK2 delta-like 2 homolog (Drosophila)
DNM3 dynamin 3
DTX2 deltex 2, E3 ubiquitin ligase
EDIL3 EGF-like repeats and discoidin I-like domains 3
F7 coagulation factor VII (serum prothrombin conversion accelerator)
FBXO22 F-box protein 22
FOXC1 forkhead box C1
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GJA8 gap junction protein, alpha 8, 50kDa
GLS2 glutaminase 2 (liver, mitochondrial)
GPNMB glycoprotein (transmembrane) nmb
HAMP hepcidin antimicrobial peptide
HHAT hedgehog acyltransferase
HIST1H1T histone cluster 1, H1t
HIST1H4D histone cluster 1, H4d
HLA-DMA major histocompatibility complex, class II, DM alpha
HOXA1 homeobox A1
HOXA4 homeobox A4
HOXC10 homeobox C10
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
IL12B interleukin 12B
IQCG IQ motif containing G
KIAA0319L KIAA0319-like
KIAA0753 KIAA0753
KIAA1107 KIAA1107
KIR2DS1 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1
KLHL29 kelch-like family member 29
KRT24 keratin 24, type I
LINS lines homolog (Drosophila)
LMO7 LIM domain 7
LOC100287590 uncharacterized LOC100287590
LOC730101 uncharacterized LOC730101
LRP5L low density lipoprotein receptor-related protein 5-like
LY6G5C lymphocyte antigen 6 complex, locus G5C
MAGEH1 melanoma antigen family H1
MDFI MyoD family inhibitor
MDM4 MDM4, p53 regulator
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MXD3 MAX dimerization protein 3
NDP Norrie disease (pseudoglioma)
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NOL12 nucleolar protein 12
NPM3 nucleophosmin/nucleoplasmin 3
OBSCN obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3
PDE12 phosphodiesterase 12
PHEX phosphate regulating endopeptidase homolog, X-linked
PLSCR2 phospholipid scramblase 2
PLXNB3 plexin B3
PMFBP1 polyamine modulated factor 1 binding protein 1
PRF1 perforin 1 (pore forming protein)
PRR15L proline rich 15-like
RPRM reprimo, TP53 dependent G2 arrest mediator candidate
SAYSD1 SAYSVFN motif domain containing 1
SCEL sciellin
SIX3 SIX homeobox 3
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
SLC39A1 solute carrier family 39 (zinc transporter), member 1
TBC1D22B TBC1 domain family, member 22B
TINAGL1 tubulointerstitial nephritis antigen-like 1
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
TRAIP TRAF interacting protein
TTC26 tetratricopeptide repeat domain 26
TUBA4B tubulin, alpha 4b
TXK TXK tyrosine kinase
UGT8 UDP glycosyltransferase 8
ZNF219 zinc finger protein 219
ZNF268 zinc finger protein 268
ZNF749 zinc finger protein 749