| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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194 genes differentially expressed following the lasalocid-6639 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| A1CF | APOBEC1 complementation factor |
| ADAM23 | ADAM metallopeptidase domain 23 |
| ATF3 | activating transcription factor 3 |
| BAGE | B melanoma antigen |
| BIRC3 | baculoviral IAP repeat containing 3 |
| BTF3P11 | basic transcription factor 3 pseudogene 11 |
| C14ORF1 | chromosome 14 open reading frame 1 |
| C1ORF54 | chromosome 1 open reading frame 54 |
| C8A | complement component 8, alpha polypeptide |
| CCKAR | cholecystokinin A receptor |
| CDC14B | cell division cycle 14B |
| CDR2 | cerebellar degeneration-related protein 2, 62kDa |
| CEACAM3 | carcinoembryonic antigen-related cell adhesion molecule 3 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 |
| DIAPH2-AS1 | DIAPH2 antisense RNA 1 |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 |
| DOCK6 | dedicator of cytokinesis 6 |
| DVL2 | dishevelled segment polarity protein 2 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 |
| EMX1 | empty spiracles homeobox 1 |
| ENPEP | glutamyl aminopeptidase (aminopeptidase A) |
| ENTPD4 | ectonucleoside triphosphate diphosphohydrolase 4 |
| FGF1 | fibroblast growth factor 1 (acidic) |
| FGF4 | fibroblast growth factor 4 |
| FLT3LG | fms-related tyrosine kinase 3 ligand |
| FRMD4B | FERM domain containing 4B |
| FYB | FYN binding protein |
| GNA15 | guanine nucleotide binding protein (G protein), alpha 15 (Gq class) |
| GSTM5 | glutathione S-transferase mu 5 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 |
| ICAM1 | intercellular adhesion molecule 1 |
| IGHA1 | immunoglobulin heavy constant alpha 1 |
| ING2 | inhibitor of growth family, member 2 |
| INSIG1 | insulin induced gene 1 |
| JUN | jun proto-oncogene |
| JUND | jun D proto-oncogene |
| KCNAB1 | potassium channel, voltage gated subfamily A regulatory beta subunit 1 |
| KCNB1 | potassium channel, voltage gated Shab related subfamily B, member 1 |
| KMO | kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) |
| KRT34 | keratin 34, type I |
| LDHC | lactate dehydrogenase C |
| LIF | leukemia inhibitory factor |
| LIMD1 | LIM domains containing 1 |
| LLGL1 | lethal giant larvae homolog 1 (Drosophila) |
| LOC202181 | SUMO-interacting motifs containing 1 pseudogene |
| LOX | lysyl oxidase |
| MAPK14 | mitogen-activated protein kinase 14 |
| MPZ | myelin protein zero |
| NEK11 | NIMA-related kinase 11 |
| NPAS1 | neuronal PAS domain protein 1 |
| NPC1 | Niemann-Pick disease, type C1 |
| OR1D2 | olfactory receptor, family 1, subfamily D, member 2 |
| PARP6 | poly (ADP-ribose) polymerase family, member 6 |
| PCDHB17P | protocadherin beta 17 pseudogene |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 |
| PIN1P1 | peptidylprolyl cis/trans isomerase, NIMA-interacting 1 pseudogene 1 |
| PLBD1 | phospholipase B domain containing 1 |
| PLK4 | polo-like kinase 4 |
| POMT2 | protein-O-mannosyltransferase 2 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A |
| PROL1 | proline rich, lacrimal 1 |
| PTPRD | protein tyrosine phosphatase, receptor type, D |
| PYY | peptide YY |
| RGS4 | regulator of G-protein signaling 4 |
| RPL10L | ribosomal protein L10-like |
| RPL35A | ribosomal protein L35a |
| RTCA | RNA 3'-terminal phosphate cyclase |
| RUNDC3A | RUN domain containing 3A |
| RUNX1 | runt-related transcription factor 1 |
| SAMD4A | sterile alpha motif domain containing 4A |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 |
| SNN | stannin |
| SPRED2 | sprouty-related, EVH1 domain containing 2 |
| SQLE | squalene epoxidase |
| SQSTM1 | sequestosome 1 |
| STS | steroid sulfatase (microsomal), isozyme S |
| SWAP70 | SWAP switching B-cell complex 70kDa subunit |
| TGFA | transforming growth factor, alpha |
| THOC5 | THO complex 5 |
| THPO | thrombopoietin |
| TIMELESS | timeless circadian clock |
| TLK1 | tousled-like kinase 1 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 |
| TNFRSF25 | tumor necrosis factor receptor superfamily, member 25 |
| TRIB3 | tribbles pseudokinase 3 |
| TUBA3C | tubulin, alpha 3c |
| UAP1L1 | UDP-N-acetylglucosamine pyrophosphorylase 1 like 1 |
| UBE2B | ubiquitin-conjugating enzyme E2B |
| UTS2 | urotensin 2 |
| VAX2 | ventral anterior homeobox 2 |
| WNT8B | wingless-type MMTV integration site family, member 8B |
| XBP1 | X-box binding protein 1 |
| ZNF165 | zinc finger protein 165 |
| Symbol | Name |
|---|---|
| ALOX12P2 | arachidonate 12-lipoxygenase pseudogene 2 |
| ANXA2P1 | annexin A2 pseudogene 1 |
| ARR3 | arrestin 3, retinal (X-arrestin) |
| ARSB | arylsulfatase B |
| B3GNT4 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4 |
| C14ORF79 | chromosome 14 open reading frame 79 |
| C4ORF19 | chromosome 4 open reading frame 19 |
| CACNA2D2 | calcium channel, voltage-dependent, alpha 2/delta subunit 2 |
| CCDC85C | coiled-coil domain containing 85C |
| CCNO | cyclin O |
| CES3 | carboxylesterase 3 |
| CFAP45 | cilia and flagella associated protein 45 |
| CHMP6 | charged multivesicular body protein 6 |
| CNGA1 | cyclic nucleotide gated channel alpha 1 |
| CNN2 | calponin 2 |
| COL9A2 | collagen, type IX, alpha 2 |
| CUZD1 | CUB and zona pellucida-like domains 1 |
| CWF19L1 | CWF19-like 1, cell cycle control (S. pombe) |
| CYBRD1 | cytochrome b reductase 1 |
| CYP2B7P | cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene |
| CYP2J2 | cytochrome P450, family 2, subfamily J, polypeptide 2 |
| CYP4F8 | cytochrome P450, family 4, subfamily F, polypeptide 8 |
| DBF4B | DBF4 zinc finger B |
| DDN | dendrin |
| DEF6 | differentially expressed in FDCP 6 homolog (mouse) |
| DLK2 | delta-like 2 homolog (Drosophila) |
| DNM3 | dynamin 3 |
| DTX2 | deltex 2, E3 ubiquitin ligase |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 |
| F7 | coagulation factor VII (serum prothrombin conversion accelerator) |
| FBXO22 | F-box protein 22 |
| FOXC1 | forkhead box C1 |
| GIT1 | G protein-coupled receptor kinase interacting ArfGAP 1 |
| GJA8 | gap junction protein, alpha 8, 50kDa |
| GLS2 | glutaminase 2 (liver, mitochondrial) |
| GPNMB | glycoprotein (transmembrane) nmb |
| HAMP | hepcidin antimicrobial peptide |
| HHAT | hedgehog acyltransferase |
| HIST1H1T | histone cluster 1, H1t |
| HIST1H4D | histone cluster 1, H4d |
| HLA-DMA | major histocompatibility complex, class II, DM alpha |
| HOXA1 | homeobox A1 |
| HOXA4 | homeobox A4 |
| HOXC10 | homeobox C10 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein |
| IL12B | interleukin 12B |
| IQCG | IQ motif containing G |
| KIAA0319L | KIAA0319-like |
| KIAA0753 | KIAA0753 |
| KIAA1107 | KIAA1107 |
| KIR2DS1 | killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1 |
| KLHL29 | kelch-like family member 29 |
| KRT24 | keratin 24, type I |
| LINS | lines homolog (Drosophila) |
| LMO7 | LIM domain 7 |
| LOC100287590 | uncharacterized LOC100287590 |
| LOC730101 | uncharacterized LOC730101 |
| LRP5L | low density lipoprotein receptor-related protein 5-like |
| LY6G5C | lymphocyte antigen 6 complex, locus G5C |
| MAGEH1 | melanoma antigen family H1 |
| MDFI | MyoD family inhibitor |
| MDM4 | MDM4, p53 regulator |
| MICAL1 | microtubule associated monooxygenase, calponin and LIM domain containing 1 |
| MRM1 | mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) |
| MXD3 | MAX dimerization protein 3 |
| NDP | Norrie disease (pseudoglioma) |
| NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
| NOL12 | nucleolar protein 12 |
| NPM3 | nucleophosmin/nucleoplasmin 3 |
| OBSCN | obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF |
| PAK3 | p21 protein (Cdc42/Rac)-activated kinase 3 |
| PDE12 | phosphodiesterase 12 |
| PHEX | phosphate regulating endopeptidase homolog, X-linked |
| PLSCR2 | phospholipid scramblase 2 |
| PLXNB3 | plexin B3 |
| PMFBP1 | polyamine modulated factor 1 binding protein 1 |
| PRF1 | perforin 1 (pore forming protein) |
| PRR15L | proline rich 15-like |
| RPRM | reprimo, TP53 dependent G2 arrest mediator candidate |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SCEL | sciellin |
| SIX3 | SIX homeobox 3 |
| SLC25A21 | solute carrier family 25 (mitochondrial oxoadipate carrier), member 21 |
| SLC39A1 | solute carrier family 39 (zinc transporter), member 1 |
| TBC1D22B | TBC1 domain family, member 22B |
| TINAGL1 | tubulointerstitial nephritis antigen-like 1 |
| TNKS2 | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 |
| TRAIP | TRAF interacting protein |
| TTC26 | tetratricopeptide repeat domain 26 |
| TUBA4B | tubulin, alpha 4b |
| TXK | TXK tyrosine kinase |
| UGT8 | UDP glycosyltransferase 8 |
| ZNF219 | zinc finger protein 219 |
| ZNF268 | zinc finger protein 268 |
| ZNF749 | zinc finger protein 749 |