latamoxef-4648 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the latamoxef-4648 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACRV1 acrosomal vesicle protein 1
ACVR1B activin A receptor, type IB
ADAM11 ADAM metallopeptidase domain 11
ADAMTS8 ADAM metallopeptidase with thrombospondin type 1 motif, 8
ADGB androglobin
ADGRB2 adhesion G protein-coupled receptor B2
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
B3GALT2 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2
BCAT2 branched chain amino-acid transaminase 2, mitochondrial
BMPR1B bone morphogenetic protein receptor, type IB
BRF1 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit
C9ORF9 chromosome 9 open reading frame 9
CABP1 calcium binding protein 1
CCL21 chemokine (C-C motif) ligand 21
CD79B CD79b molecule, immunoglobulin-associated beta
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CEBPE CCAAT/enhancer binding protein (C/EBP), epsilon
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal)
CHRNA6 cholinergic receptor, nicotinic, alpha 6 (neuronal)
CNPY4 canopy FGF signaling regulator 4
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CRYGD crystallin, gamma D
CSDC2 cold shock domain containing C2, RNA binding
CSF1 colony stimulating factor 1 (macrophage)
CXCR2 chemokine (C-X-C motif) receptor 2
CYP4F8 cytochrome P450, family 4, subfamily F, polypeptide 8
DAPK2 death-associated protein kinase 2
DOCK3 dedicator of cytokinesis 3
DSC1 desmocollin 1
EDN3 endothelin 3
EGFL7 EGF-like-domain, multiple 7
EML2 echinoderm microtubule associated protein like 2
ENG endoglin
ENPEP glutamyl aminopeptidase (aminopeptidase A)
ESR1 estrogen receptor 1
FCGR2C Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)
FGB fibrinogen beta chain
FGF1 fibroblast growth factor 1 (acidic)
FOLH1 folate hydrolase (prostate-specific membrane antigen) 1
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
GAS1 growth arrest-specific 1
GNL3LP1 guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1
GPR135 G protein-coupled receptor 135
GSTA1 glutathione S-transferase alpha 1
HIST1H1D histone cluster 1, H1d
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H)
HPR haptoglobin-related protein
HTR1F 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled
IGLV3-19 immunoglobulin lambda variable 3-19
IL5RA interleukin 5 receptor, alpha
ING2 inhibitor of growth family, member 2
ISG20L2 interferon stimulated exonuclease gene 20kDa-like 2
KALRN kalirin, RhoGEF kinase
KCNA6 potassium channel, voltage gated shaker related subfamily A, member 6
KCNH1 potassium channel, voltage gated eag related subfamily H, member 1
KIAA0040 KIAA0040
KIAA1109 KIAA1109
KIF1A kinesin family member 1A
LRRN2 leucine rich repeat neuronal 2
LSAMP limbic system-associated membrane protein
LST1 leukocyte specific transcript 1
MGAT3 mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
MILR1 mast cell immunoglobulin-like receptor 1
MTSS1L metastasis suppressor 1-like
MYH7 myosin, heavy chain 7, cardiac muscle, beta
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NIPAL2 NIPA-like domain containing 2
NIPAL3 NIPA-like domain containing 3
PCDHB3 protocadherin beta 3
PDE4DIP phosphodiesterase 4D interacting protein
POU5F1B POU class 5 homeobox 1B
PYY peptide YY
RALYL RALY RNA binding protein-like
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated)
RCVRN recoverin
REPS1 RALBP1 associated Eps domain containing 1
RGR retinal G protein coupled receptor
RPL23AP32 ribosomal protein L23a pseudogene 32
RPS4Y1 ribosomal protein S4, Y-linked 1
RUNX1T1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
SCUBE3 signal peptide, CUB domain, EGF-like 3
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3
SIGLEC8 sialic acid binding Ig-like lectin 8
SLC26A3 solute carrier family 26 (anion exchanger), member 3
SLC8A2 solute carrier family 8 (sodium/calcium exchanger), member 2
SPTBN5 spectrin, beta, non-erythrocytic 5
ST8SIA4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
TIMELESS timeless circadian clock
TMPRSS4 transmembrane protease, serine 4
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TNKS tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
TRO trophinin
TSHR thyroid stimulating hormone receptor
TTC12 tetratricopeptide repeat domain 12
TYMP thymidine phosphorylase
ZNF223 zinc finger protein 223
ZNF280B zinc finger protein 280B

decreased expression

Symbol Name
ABCA11P ATP-binding cassette, sub-family A (ABC1), member 11, pseudogene
ADCY6 adenylate cyclase 6
ALPK1 alpha-kinase 1
ANKFY1 ankyrin repeat and FYVE domain containing 1
ARL14 ADP-ribosylation factor-like 14
ATF7IP2 activating transcription factor 7 interacting protein 2
B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
BAG4 BCL2-associated athanogene 4
BCKDHA branched chain keto acid dehydrogenase E1, alpha polypeptide
BIRC3 baculoviral IAP repeat containing 3
C16ORF59 chromosome 16 open reading frame 59
C1ORF105 chromosome 1 open reading frame 105
C4ORF19 chromosome 4 open reading frame 19
C4ORF29 chromosome 4 open reading frame 29
CASD1 CAS1 domain containing 1
CBX4 chromobox homolog 4
CCS copper chaperone for superoxide dismutase
CGREF1 cell growth regulator with EF-hand domain 1
CHST10 carbohydrate sulfotransferase 10
CIR1 corepressor interacting with RBPJ, 1
CLCN5 chloride channel, voltage-sensitive 5
CRELD1 cysteine-rich with EGF-like domains 1
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DENND4A DENN/MADD domain containing 4A
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
DIXDC1 DIX domain containing 1
EML4 echinoderm microtubule associated protein like 4
ERMAP erythroblast membrane-associated protein (Scianna blood group)
FANCF Fanconi anemia, complementation group F
FZD3 frizzled class receptor 3
GAREM GRB2 associated, regulator of MAPK1
GDAP1 ganglioside induced differentiation associated protein 1
GLCE glucuronic acid epimerase
HLX H2.0-like homeobox
HMOX1 heme oxygenase 1
HOXA1 homeobox A1
HP1BP3 heterochromatin protein 1, binding protein 3
HSD17B14 hydroxysteroid (17-beta) dehydrogenase 14
IL11RA interleukin 11 receptor, alpha
IL17RA interleukin 17 receptor A
INCENP inner centromere protein antigens 135/155kDa
IPO8 importin 8
IPPK inositol 1,3,4,5,6-pentakisphosphate 2-kinase
JMJD4 jumonji domain containing 4
KCTD20 potassium channel tetramerization domain containing 20
KIAA1462 KIAA1462
KLF3 Kruppel-like factor 3 (basic)
KLF7 Kruppel-like factor 7 (ubiquitous)
LIG3 ligase III, DNA, ATP-dependent
LIG4 ligase IV, DNA, ATP-dependent
LRP5L low density lipoprotein receptor-related protein 5-like
MAMLD1 mastermind-like domain containing 1
MAN2C1 mannosidase, alpha, class 2C, member 1
MANBA mannosidase, beta A, lysosomal
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MBTD1 mbt domain containing 1
MEIS3P1 Meis homeobox 3 pseudogene 1
MFGE8 milk fat globule-EGF factor 8 protein
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MVP major vault protein
NMNAT2 nicotinamide nucleotide adenylyltransferase 2
NOL12 nucleolar protein 12
NXPH4 neurexophilin 4
OPLAH 5-oxoprolinase (ATP-hydrolysing)
OSMR oncostatin M receptor
PALMD palmdelphin
PAX9 paired box 9
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PLCD1 phospholipase C, delta 1
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
RABEP1 rabaptin, RAB GTPase binding effector protein 1
RHOBTB2 Rho-related BTB domain containing 2
RPP25 ribonuclease P/MRP 25kDa subunit
RRAGB Ras-related GTP binding B
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
SARS2 seryl-tRNA synthetase 2, mitochondrial
SCGB2A2 secretoglobin, family 2A, member 2
SETD6 SET domain containing 6
SETD8 SET domain containing (lysine methyltransferase) 8
SGPP1 sphingosine-1-phosphate phosphatase 1
SND1-IT1 SND1 intronic transcript 1
SNIP1 Smad nuclear interacting protein 1
STAG3L4 stromal antigen 3-like 4 (pseudogene)
TAGLN3 transgelin 3
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TEX40 testis expressed 40
TMBIM1 transmembrane BAX inhibitor motif containing 1
TMEM121 transmembrane protein 121
TMEM183A transmembrane protein 183A
TRAPPC13 trafficking protein particle complex 13
TRIM16 tripartite motif containing 16
TRIM21 tripartite motif containing 21
TWISTNB TWIST neighbor
WDR76 WD repeat domain 76
ZNF232 zinc finger protein 232
ZNF280D zinc finger protein 280D
ZNF358 zinc finger protein 358
ZNF611 zinc finger protein 611
ZNF711 zinc finger protein 711