late endosome Gene Set

Dataset LOCATE Curated Protein Localization Annotations
Category proteomics
Type cellular component
Description A prelysosomal endocytic organelle differentiated from early endosomes by lower lumenal pH and different protein composition. Late endosomes are more spherical than early endosomes and are mostly juxtanuclear, being concentrated near the microtubule organizing center. (Gene Ontology, GO_0005770)
External Link http://locate.imb.uq.edu.au/searchpages/HumanGO:0005770.shtml
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Genes

29 proteins localized to the late endosome cellular component in low- or high-throughput protein localization assays from the LOCATE Curated Protein Localization Annotations dataset.

Symbol Name
ABCA5 ATP-binding cassette, sub-family A (ABC1), member 5
CD151 CD151 molecule (Raph blood group)
CLCN3 chloride channel, voltage-sensitive 3
CLCN7 chloride channel, voltage-sensitive 7
DIABLO diablo, IAP-binding mitochondrial protein
LAMTOR2 late endosomal/lysosomal adaptor, MAPK and MTOR activator 2
LAMTOR3 late endosomal/lysosomal adaptor, MAPK and MTOR activator 3
LAPTM4A lysosomal protein transmembrane 4 alpha
MMD monocyte to macrophage differentiation-associated
NEK5 NIMA-related kinase 5
NPC1 Niemann-Pick disease, type C1
PRKCZ protein kinase C, zeta
RAB24 RAB24, member RAS oncogene family
RAB29 RAB29, member RAS oncogene family
RAB9A RAB9A, member RAS oncogene family
RAP1A RAP1A, member of RAS oncogene family
RNF128 ring finger protein 128, E3 ubiquitin protein ligase
SLC31A2 solute carrier family 31 (copper transporter), member 2
SNAP23 synaptosomal-associated protein, 23kDa
SNX16 sorting nexin 16
SPPL2B signal peptide peptidase like 2B
STARD3 StAR-related lipid transfer (START) domain containing 3
STARD3NL STARD3 N-terminal like
STX7 syntaxin 7
VPS11 vacuolar protein sorting 11 homolog (S. cerevisiae)
VPS16 vacuolar protein sorting 16 homolog (S. cerevisiae)
VPS18 vacuolar protein sorting 18 homolog (S. cerevisiae)
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
Funding