latrunculin A Gene Set

Dataset CTD Gene-Chemical Interactions
Category physical interactions
Type chemical
Description A bicyclic macrolide natural product consisting of a 16-membered bicyclic lactone attached to the rare 2-thiazolidinone moiety. It is obtained from the Red Sea sponge Latrunculia magnifica and from the Fiji Islands sponge Cacospongia mycofijiensis. Latrunculin A inhibits actin polymerisation, microfilament organsation and microfilament-mediated processes. (Chemical Entities of Biological Interest Ontology, CHEBI_69136)
External Link http://ctdbase.org/detail.go?type=chem&acc=C037067
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Genes

5 genes/proteins interacting with the chemical latrunculin A from the curated CTD Gene-Chemical Interactions dataset.

Symbol Name
ACTB actin, beta
CASP3 caspase 3, apoptosis-related cysteine peptidase
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
PRLR prolactin receptor