leading edge membrane Gene Set

Dataset GO Cellular Component Annotations 2015
Category structural or functional annotations
Type cellular component
Description The portion of the plasma membrane surrounding the leading edge of a motile cell. (Gene Ontology, GO_0031256)
External Link http://amigo.geneontology.org/amigo/term/GO:0031256
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Genes

123 proteins localized to the leading edge membrane cellular component from the curated GO Cellular Component Annotations 2015 dataset.

Symbol Name
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ADAM17 ADAM metallopeptidase domain 17
ADGRE2 adhesion G protein-coupled receptor E2
ADORA1 adenosine A1 receptor
AIF1 allograft inflammatory factor 1
AIF1L allograft inflammatory factor 1-like
AKT2 v-akt murine thymoma viral oncogene homolog 2
AMPH amphiphysin
ANK1 ankyrin 1, erythrocytic
ANTXR1 anthrax toxin receptor 1
APC adenomatous polyposis coli
APC2 adenomatosis polyposis coli 2
ARF4 ADP-ribosylation factor 4
ARHGAP44 Rho GTPase activating protein 44
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ATF4 activating transcription factor 4
BMX BMX non-receptor tyrosine kinase
C2CD5 C2 calcium-dependent domain containing 5
CDC37 cell division cycle 37
CDC42 cell division cycle 42
CDKL5 cyclin-dependent kinase-like 5
CFL1 cofilin 1 (non-muscle)
CIB1 calcium and integrin binding 1 (calmyrin)
CLASP2 cytoplasmic linker associated protein 2
CNTNAP2 contactin associated protein-like 2
CSPG4 chondroitin sulfate proteoglycan 4
DDN dendrin
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DIAPH1 diaphanous-related formin 1
DLC1 DLC1 Rho GTPase activating protein
DPP4 dipeptidyl-peptidase 4
EEF1A1 eukaryotic translation elongation factor 1 alpha 1
EPB41L3 erythrocyte membrane protein band 4.1-like 3
EPB41L5 erythrocyte membrane protein band 4.1 like 5
EPHA2 EPH receptor A2
EPS8 epidermal growth factor receptor pathway substrate 8
EPS8L1 EPS8-like 1
EPS8L2 EPS8-like 2
EZR ezrin
FAP fibroblast activation protein, alpha
FERMT1 fermitin family member 1
FERMT2 fermitin family member 2
FGD2 FYVE, RhoGEF and PH domain containing 2
FGD5 FYVE, RhoGEF and PH domain containing 5
FGR FGR proto-oncogene, Src family tyrosine kinase
GABARAPL1 GABA(A) receptor-associated protein like 1
GABRG2 gamma-aminobutyric acid (GABA) A receptor, gamma 2
GPER1 G protein-coupled estrogen receptor 1
GRIA1 glutamate receptor, ionotropic, AMPA 1
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1
IFIT5 interferon-induced protein with tetratricopeptide repeats 5
INPP5K inositol polyphosphate-5-phosphatase K
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
ITGA8 integrin, alpha 8
ITGAV integrin, alpha V
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
KANK1 KN motif and ankyrin repeat domains 1
KCNA2 potassium channel, voltage gated shaker related subfamily A, member 2
KCNB1 potassium channel, voltage gated Shab related subfamily B, member 1
KCNC1 potassium channel, voltage gated Shaw related subfamily C, member 1
KCNC3 potassium channel, voltage gated Shaw related subfamily C, member 3
KCNJ11 potassium channel, inwardly rectifying subfamily J, member 11
LAMP5 lysosomal-associated membrane protein family, member 5
LCP1 lymphocyte cytosolic protein 1 (L-plastin)
MACF1 microtubule-actin crosslinking factor 1
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
MYO1D myosin ID
MYO1G myosin IG
MYO6 myosin VI
NCKAP1 NCK-associated protein 1
NF2 neurofibromin 2 (merlin)
NME1 NME/NM23 nucleoside diphosphate kinase 1
OPRD1 opioid receptor, delta 1
OPRM1 opioid receptor, mu 1
PACSIN1 protein kinase C and casein kinase substrate in neurons 1
PACSIN2 protein kinase C and casein kinase substrate in neurons 2
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PALM paralemmin
PDE4A phosphodiesterase 4A, cAMP-specific
PDE9A phosphodiesterase 9A
PDPN podoplanin
PDXP pyridoxal (pyridoxine, vitamin B6) phosphatase
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
PLA2G4F phospholipase A2, group IVF
PLEK pleckstrin
PLEK2 pleckstrin 2
PLEKHA1 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
PPP1R9B protein phosphatase 1, regulatory subunit 9B
PTPRJ protein tyrosine phosphatase, receptor type, J
PTPRK protein tyrosine phosphatase, receptor type, K
RAB34 RAB34, member RAS oncogene family
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated)
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
ROBO2 roundabout, axon guidance receptor, homolog 2 (Drosophila)
RPS3 ribosomal protein S3
SCIMP SLP adaptor and CSK interacting membrane protein
SGCE sarcoglycan, epsilon
SH3YL1 SH3 and SYLF domain containing 1
SHISA9 shisa family member 9
SLC1A2 solute carrier family 1 (glial high affinity glutamate transporter), member 2
SLC39A6 solute carrier family 39 (zinc transporter), member 6
SNTG1 syntrophin, gamma 1
SPATA13 spermatogenesis associated 13
SPRY2 sprouty homolog 2 (Drosophila)
SPRY4 sprouty homolog 4 (Drosophila)
SPTBN1 spectrin, beta, non-erythrocytic 1
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SYNE2 spectrin repeat containing, nuclear envelope 2
TACR3 tachykinin receptor 3
TESC tescalcin
THEM4 thioesterase superfamily member 4
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein
TLN1 talin 1
TPM1 tropomyosin 1 (alpha)
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TRPV4 transient receptor potential cation channel, subfamily V, member 4
TWF1 twinfilin actin binding protein 1
VASP vasodilator-stimulated phosphoprotein
WLS wntless Wnt ligand secretion mediator
WWC1 WW and C2 domain containing 1