| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the leflunomide-2539 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AAK1 | AP2 associated kinase 1 |
| ACSBG1 | acyl-CoA synthetase bubblegum family member 1 |
| AGFG2 | ArfGAP with FG repeats 2 |
| AHNAK | AHNAK nucleoprotein |
| B4GALT6 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6 |
| BFSP1 | beaded filament structural protein 1, filensin |
| BTG2 | BTG family, member 2 |
| C1QTNF1 | C1q and tumor necrosis factor related protein 1 |
| C1QTNF3 | C1q and tumor necrosis factor related protein 3 |
| CCNT2 | cyclin T2 |
| CCR7 | chemokine (C-C motif) receptor 7 |
| CCSER2 | coiled-coil serine-rich protein 2 |
| CCZ1 | CCZ1 vacuolar protein trafficking and biogenesis associated homolog (S. cerevisiae) |
| CHST7 | carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7 |
| COL10A1 | collagen, type X, alpha 1 |
| CREM | cAMP responsive element modulator |
| CYP4F11 | cytochrome P450, family 4, subfamily F, polypeptide 11 |
| DCLK2 | doublecortin-like kinase 2 |
| DMP1 | dentin matrix acidic phosphoprotein 1 |
| DNAAF1 | dynein, axonemal, assembly factor 1 |
| DNMBP | dynamin binding protein |
| DPYSL4 | dihydropyrimidinase-like 4 |
| DSTYK | dual serine/threonine and tyrosine protein kinase |
| DTX2 | deltex 2, E3 ubiquitin ligase |
| DUSP4 | dual specificity phosphatase 4 |
| EXTL3 | exostosin-like glycosyltransferase 3 |
| EZH1 | enhancer of zeste 1 polycomb repressive complex 2 subunit |
| FGF17 | fibroblast growth factor 17 |
| GPR1 | G protein-coupled receptor 1 |
| GRK4 | G protein-coupled receptor kinase 4 |
| HIST1H2AE | histone cluster 1, H2ae |
| HIST1H3C | histone cluster 1, H3c |
| HNF1B | HNF1 homeobox B |
| HTR1B | 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled |
| HTR2A | 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled |
| IDI2-AS1 | IDI2 antisense RNA 1 |
| ING4 | inhibitor of growth family, member 4 |
| JAK3 | Janus kinase 3 |
| KANSL3 | KAT8 regulatory NSL complex subunit 3 |
| KAZALD1 | Kazal-type serine peptidase inhibitor domain 1 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 |
| KYNU | kynureninase |
| L3MBTL1 | l(3)mbt-like 1 (Drosophila) |
| LRRN2 | leucine rich repeat neuronal 2 |
| LYVE1 | lymphatic vessel endothelial hyaluronan receptor 1 |
| MAP7 | microtubule-associated protein 7 |
| MAPK10 | mitogen-activated protein kinase 10 |
| MAPK8IP3 | mitogen-activated protein kinase 8 interacting protein 3 |
| MMP24 | matrix metallopeptidase 24 (membrane-inserted) |
| MOB3B | MOB kinase activator 3B |
| MPPE1 | metallophosphoesterase 1 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming |
| MYO6 | myosin VI |
| NIPAL2 | NIPA-like domain containing 2 |
| NLRP1 | NLR family, pyrin domain containing 1 |
| NPFF | neuropeptide FF-amide peptide precursor |
| NPVF | neuropeptide VF precursor |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| NT5E | 5'-nucleotidase, ecto (CD73) |
| PAWR | PRKC, apoptosis, WT1, regulator |
| PCSK6 | proprotein convertase subtilisin/kexin type 6 |
| PDGFRL | platelet-derived growth factor receptor-like |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 |
| PHF20L1 | PHD finger protein 20-like 1 |
| PLEK2 | pleckstrin 2 |
| PLXNC1 | plexin C1 |
| PPP1R2P9 | protein phosphatase 1, regulatory (inhibitor) subunit 2 pseudogene 9 |
| PRM2 | protamine 2 |
| PRO2964 | uncharacterized protein PRO2964 |
| PROX1 | prospero homeobox 1 |
| PRY | PTPN13-like, Y-linked |
| RAB11FIP5 | RAB11 family interacting protein 5 (class I) |
| RARA | retinoic acid receptor, alpha |
| RBFOX1 | RNA binding protein, fox-1 homolog (C. elegans) 1 |
| RHO | rhodopsin |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| RTEL1 | regulator of telomere elongation helicase 1 |
| SETBP1 | SET binding protein 1 |
| SEZ6L | seizure related 6 homolog (mouse)-like |
| SIGLEC8 | sialic acid binding Ig-like lectin 8 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 |
| SLCO2B1 | solute carrier organic anion transporter family, member 2B1 |
| SMTN | smoothelin |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 |
| SPTBN5 | spectrin, beta, non-erythrocytic 5 |
| STOML1 | stomatin (EPB72)-like 1 |
| SYNDIG1 | synapse differentiation inducing 1 |
| TEF | thyrotrophic embryonic factor |
| THBS1 | thrombospondin 1 |
| TMCC2 | transmembrane and coiled-coil domain family 2 |
| TP53I3 | tumor protein p53 inducible protein 3 |
| TROVE2 | TROVE domain family, member 2 |
| TTC28 | tetratricopeptide repeat domain 28 |
| UGT2B17 | UDP glucuronosyltransferase 2 family, polypeptide B17 |
| ZBTB17 | zinc finger and BTB domain containing 17 |
| ZNF444 | zinc finger protein 444 |
| ZXDB | zinc finger, X-linked, duplicated B |
| Symbol | Name |
|---|---|
| ACAD10 | acyl-CoA dehydrogenase family, member 10 |
| ACADS | acyl-CoA dehydrogenase, C-2 to C-3 short chain |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 |
| AMDHD2 | amidohydrolase domain containing 2 |
| APOBEC2 | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2 |
| ARG1 | arginase 1 |
| ARHGEF26 | Rho guanine nucleotide exchange factor (GEF) 26 |
| ARRB1 | arrestin, beta 1 |
| ASPN | asporin |
| ATAT1 | alpha tubulin acetyltransferase 1 |
| C11ORF30 | chromosome 11 open reading frame 30 |
| CA5BP1 | carbonic anhydrase VB pseudogene 1 |
| CCDC106 | coiled-coil domain containing 106 |
| CDHR2 | cadherin-related family member 2 |
| CHML | choroideremia-like (Rab escort protein 2) |
| CHMP7 | charged multivesicular body protein 7 |
| CHRNA5 | cholinergic receptor, nicotinic, alpha 5 (neuronal) |
| CLEC2D | C-type lectin domain family 2, member D |
| COQ6 | coenzyme Q6 monooxygenase |
| CPNE7 | copine VII |
| CTC1 | CTS telomere maintenance complex component 1 |
| DCAF13 | DDB1 and CUL4 associated factor 13 |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| EDAR | ectodysplasin A receptor |
| EFNA3 | ephrin-A3 |
| ELAC1 | elaC ribonuclease Z 1 |
| ELP6 | elongator acetyltransferase complex subunit 6 |
| EMILIN2 | elastin microfibril interfacer 2 |
| FKBP9 | FK506 binding protein 9, 63 kDa |
| FRMPD1 | FERM and PDZ domain containing 1 |
| GAA | glucosidase, alpha; acid |
| GLRA1 | glycine receptor, alpha 1 |
| GPRIN2 | G protein regulated inducer of neurite outgrowth 2 |
| HAAO | 3-hydroxyanthranilate 3,4-dioxygenase |
| HCG4 | HLA complex group 4 (non-protein coding) |
| HPR | haptoglobin-related protein |
| HYAL4 | hyaluronoglucosaminidase 4 |
| IFT140 | intraflagellar transport 140 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 |
| INCENP | inner centromere protein antigens 135/155kDa |
| KCNA3 | potassium channel, voltage gated shaker related subfamily A, member 3 |
| KCNA6 | potassium channel, voltage gated shaker related subfamily A, member 6 |
| KCNAB3 | potassium channel, voltage gated subfamily A regulatory beta subunit 3 |
| KDM8 | lysine (K)-specific demethylase 8 |
| KLF1 | Kruppel-like factor 1 (erythroid) |
| LOC257152 | uncharacterized LOC257152 |
| LSM14B | LSM14B, SCD6 homolog B (S. cerevisiae) |
| LZTR1 | leucine-zipper-like transcription regulator 1 |
| MC1R | melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) |
| ME3 | malic enzyme 3, NADP(+)-dependent, mitochondrial |
| MMP9 | matrix metallopeptidase 9 |
| MTA2 | metastasis associated 1 family, member 2 |
| MTSS1L | metastasis suppressor 1-like |
| MVD | mevalonate (diphospho) decarboxylase |
| MYOC | myocilin, trabecular meshwork inducible glucocorticoid response |
| N6AMT1 | N-6 adenine-specific DNA methyltransferase 1 (putative) |
| NCS1 | neuronal calcium sensor 1 |
| NEUROD4 | neuronal differentiation 4 |
| NFE2L3 | nuclear factor, erythroid 2-like 3 |
| NMB | neuromedin B |
| NNAT | neuronatin |
| NXF2 | nuclear RNA export factor 2 |
| PIGL | phosphatidylinositol glycan anchor biosynthesis, class L |
| PLCD1 | phospholipase C, delta 1 |
| POLM | polymerase (DNA directed), mu |
| POM121L2 | POM121 transmembrane nucleoporin-like 2 |
| PRR7 | proline rich 7 (synaptic) |
| RAPGEFL1 | Rap guanine nucleotide exchange factor (GEF)-like 1 |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RPA4 | replication protein A4, 30kDa |
| SGTA | small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha |
| SHPK | sedoheptulokinase |
| SLAMF7 | SLAM family member 7 |
| SLC16A4 | solute carrier family 16, member 4 |
| SLC27A5 | solute carrier family 27 (fatty acid transporter), member 5 |
| SLC35F6 | solute carrier family 35, member F6 |
| SLC9A2 | solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2 |
| SPEF1 | sperm flagellar 1 |
| SPRR2B | small proline-rich protein 2B |
| STEAP4 | STEAP family member 4 |
| TAF13 | TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa |
| TBXAS1 | thromboxane A synthase 1 (platelet) |
| TEC | tec protein tyrosine kinase |
| TET3 | tet methylcytosine dioxygenase 3 |
| THBS3 | thrombospondin 3 |
| TTC4 | tetratricopeptide repeat domain 4 |
| TTLL1 | tubulin tyrosine ligase-like family member 1 |
| TWISTNB | TWIST neighbor |
| ULBP2 | UL16 binding protein 2 |
| UNC93B1 | unc-93 homolog B1 (C. elegans) |
| UPB1 | ureidopropionase, beta |
| USB1 | U6 snRNA biogenesis 1 |
| VEGFB | vascular endothelial growth factor B |
| VPS33A | vacuolar protein sorting 33 homolog A (S. cerevisiae) |
| XPNPEP3 | X-prolyl aminopeptidase 3, mitochondrial |
| ZCWPW1 | zinc finger, CW type with PWWP domain 1 |
| ZNF747 | zinc finger protein 747 |
| ZNF768 | zinc finger protein 768 |
