| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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194 genes differentially expressed following the leflunomide-5884 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AKR1C2 | aldo-keto reductase family 1, member C2 |
| ALDH1B1 | aldehyde dehydrogenase 1 family, member B1 |
| ARMCX4 | armadillo repeat containing, X-linked 4 |
| ASAP3 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 |
| ATPAF2 | ATP synthase mitochondrial F1 complex assembly factor 2 |
| C2ORF68 | chromosome 2 open reading frame 68 |
| CACTIN | cactin, spliceosome C complex subunit |
| CD47 | CD47 molecule |
| CELSR2 | cadherin, EGF LAG seven-pass G-type receptor 2 |
| CLUHP3 | clustered mitochondria (cluA/CLU1) homolog pseudogene 3 |
| CNPY4 | canopy FGF signaling regulator 4 |
| CNR2 | cannabinoid receptor 2 (macrophage) |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 |
| DHODH | dihydroorotate dehydrogenase (quinone) |
| DIO2 | deiodinase, iodothyronine, type II |
| DNAL4 | dynein, axonemal, light chain 4 |
| DPF3 | D4, zinc and double PHD fingers, family 3 |
| EDN1 | endothelin 1 |
| EFCAB11 | EF-hand calcium binding domain 11 |
| ELMO2 | engulfment and cell motility 2 |
| EPHA4 | EPH receptor A4 |
| FAM198B | family with sequence similarity 198, member B |
| FLT4 | fms-related tyrosine kinase 4 |
| FYB | FYN binding protein |
| GHRHR | growth hormone releasing hormone receptor |
| GLRA1 | glycine receptor, alpha 1 |
| GNL3LP1 | guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1 |
| GPX2 | glutathione peroxidase 2 |
| GRIP2 | glutamate receptor interacting protein 2 |
| HDAC5 | histone deacetylase 5 |
| HSD17B14 | hydroxysteroid (17-beta) dehydrogenase 14 |
| IGHG1 | immunoglobulin heavy constant gamma 1 (G1m marker) |
| IL1RAPL2 | interleukin 1 receptor accessory protein-like 2 |
| JADE2 | jade family PHD finger 2 |
| KCTD17 | potassium channel tetramerization domain containing 17 |
| KIF26B | kinesin family member 26B |
| LAMB4 | laminin, beta 4 |
| LCP2 | lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) |
| LLPH | LLP homolog, long-term synaptic facilitation (Aplysia) |
| LOC390998 | ribosomal protein L10 pseudogene |
| MAP7 | microtubule-associated protein 7 |
| MBD3 | methyl-CpG binding domain protein 3 |
| MCC | mutated in colorectal cancers |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 |
| MST1 | macrophage stimulating 1 |
| NF1 | neurofibromin 1 |
| NMBR | neuromedin B receptor |
| NPIPB15 | nuclear pore complex interacting protein family, member B15 |
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 |
| NUCB1 | nucleobindin 1 |
| ORAI2 | ORAI calcium release-activated calcium modulator 2 |
| PAX2 | paired box 2 |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PEX5L | peroxisomal biogenesis factor 5-like |
| PKNOX2 | PBX/knotted 1 homeobox 2 |
| PLEKHF1 | pleckstrin homology domain containing, family F (with FYVE domain) member 1 |
| PLXDC1 | plexin domain containing 1 |
| PMP2 | peripheral myelin protein 2 |
| POLL | polymerase (DNA directed), lambda |
| POLR2J4 | polymerase (RNA) II (DNA directed) polypeptide J4, pseudogene |
| POU3F2 | POU class 3 homeobox 2 |
| PRDM2 | PR domain containing 2, with ZNF domain |
| PSD3 | pleckstrin and Sec7 domain containing 3 |
| PTGFR | prostaglandin F receptor (FP) |
| RAD23B | RAD23 homolog B (S. cerevisiae) |
| RAG2 | recombination activating gene 2 |
| RECQL5 | RecQ protein-like 5 |
| RGS10 | regulator of G-protein signaling 10 |
| RUNX1-IT1 | RUNX1 intronic transcript 1 |
| RUSC2 | RUN and SH3 domain containing 2 |
| SCARA3 | scavenger receptor class A, member 3 |
| SENP5 | SUMO1/sentrin specific peptidase 5 |
| SERPINB3 | serpin peptidase inhibitor, clade B (ovalbumin), member 3 |
| SIX3 | SIX homeobox 3 |
| SKIL | SKI-like proto-oncogene |
| SLC1A7 | solute carrier family 1 (glutamate transporter), member 7 |
| SLC35F6 | solute carrier family 35, member F6 |
| SLCO1C1 | solute carrier organic anion transporter family, member 1C1 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 |
| SPTBN5 | spectrin, beta, non-erythrocytic 5 |
| SRD5A2 | steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2) |
| STOML1 | stomatin (EPB72)-like 1 |
| SULT1A2 | sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2 |
| SYK | spleen tyrosine kinase |
| TACR1 | tachykinin receptor 1 |
| TBC1D5 | TBC1 domain family, member 5 |
| TCL6 | T-cell leukemia/lymphoma 6 (non-protein coding) |
| TEKT2 | tektin 2 (testicular) |
| TGFA | transforming growth factor, alpha |
| TJP3 | tight junction protein 3 |
| TLE4 | transducin-like enhancer of split 4 |
| TLN2 | talin 2 |
| TNFRSF25 | tumor necrosis factor receptor superfamily, member 25 |
| TSPAN8 | tetraspanin 8 |
| UPK1B | uroplakin 1B |
| VAV3 | vav 3 guanine nucleotide exchange factor |
| WDR19 | WD repeat domain 19 |
| WNT8B | wingless-type MMTV integration site family, member 8B |
| ZNF710 | zinc finger protein 710 |
| ZNF79 | zinc finger protein 79 |
| Symbol | Name |
|---|---|
| ABCA11P | ATP-binding cassette, sub-family A (ABC1), member 11, pseudogene |
| ALG12 | ALG12, alpha-1,6-mannosyltransferase |
| ANKZF1 | ankyrin repeat and zinc finger domain containing 1 |
| APOL6 | apolipoprotein L, 6 |
| APOLD1 | apolipoprotein L domain containing 1 |
| BCL2L2 | BCL2-like 2 |
| C1ORF56 | chromosome 1 open reading frame 56 |
| C8ORF60 | chromosome 8 open reading frame 60 |
| CDK3 | cyclin-dependent kinase 3 |
| CDKL3 | cyclin-dependent kinase-like 3 |
| CFAP44 | cilia and flagella associated protein 44 |
| CFAP69 | cilia and flagella associated protein 69 |
| COQ6 | coenzyme Q6 monooxygenase |
| CTSK | cathepsin K |
| CYP20A1 | cytochrome P450, family 20, subfamily A, polypeptide 1 |
| DEAF1 | DEAF1 transcription factor |
| EN1 | engrailed homeobox 1 |
| ERF | Ets2 repressor factor |
| EVPL | envoplakin |
| F8 | coagulation factor VIII, procoagulant component |
| FGD6 | FYVE, RhoGEF and PH domain containing 6 |
| FKBP1B | FK506 binding protein 1B, 12.6 kDa |
| GLDC | glycine dehydrogenase (decarboxylating) |
| GLI3 | GLI family zinc finger 3 |
| GPR1 | G protein-coupled receptor 1 |
| HOXB9 | homeobox B9 |
| IFNA14 | interferon, alpha 14 |
| IL4R | interleukin 4 receptor |
| INCENP | inner centromere protein antigens 135/155kDa |
| INF2 | inverted formin, FH2 and WH2 domain containing |
| IRAK4 | interleukin-1 receptor-associated kinase 4 |
| IRF1 | interferon regulatory factor 1 |
| KIAA0895 | KIAA0895 |
| KIAA1462 | KIAA1462 |
| LGMN | legumain |
| LHX6 | LIM homeobox 6 |
| LOC100286895 | cell division cycle 27 homolog pseudogene |
| LOC730101 | uncharacterized LOC730101 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MAZ | MYC-associated zinc finger protein (purine-binding transcription factor) |
| MCRS1 | microspherule protein 1 |
| MFSD11 | major facilitator superfamily domain containing 11 |
| MGAT1 | mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase |
| MITF | microphthalmia-associated transcription factor |
| MKS1 | Meckel syndrome, type 1 |
| MVP | major vault protein |
| NOL12 | nucleolar protein 12 |
| NR2C2 | nuclear receptor subfamily 2, group C, member 2 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa |
| P3H2 | prolyl 3-hydroxylase 2 |
| PAK6 | p21 protein (Cdc42/Rac)-activated kinase 6 |
| PDE8B | phosphodiesterase 8B |
| PID1 | phosphotyrosine interaction domain containing 1 |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
| PLSCR4 | phospholipid scramblase 4 |
| POLM | polymerase (DNA directed), mu |
| PRMT7 | protein arginine methyltransferase 7 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) |
| RASSF1 | Ras association (RalGDS/AF-6) domain family member 1 |
| RGCC | regulator of cell cycle |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RPS17P5 | ribosomal protein S17 pseudogene 5 |
| RRP9 | ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast) |
| RUFY2 | RUN and FYVE domain containing 2 |
| SCN1B | sodium channel, voltage gated, type I beta subunit |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SIX1 | SIX homeobox 1 |
| SLC25A40 | solute carrier family 25, member 40 |
| SLC29A3 | solute carrier family 29 (equilibrative nucleoside transporter), member 3 |
| SLC5A6 | solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 |
| SNHG3 | small nucleolar RNA host gene 3 |
| TCTN1 | tectonic family member 1 |
| TEX2 | testis expressed 2 |
| TEX40 | testis expressed 40 |
| TGFB3 | transforming growth factor, beta 3 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase |
| TMEM2 | transmembrane protein 2 |
| TRIM21 | tripartite motif containing 21 |
| TRMU | tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase |
| TSKU | tsukushi, small leucine rich proteoglycan |
| TTLL7 | tubulin tyrosine ligase-like family member 7 |
| USP20 | ubiquitin specific peptidase 20 |
| ZBED1 | zinc finger, BED-type containing 1 |
| ZBTB10 | zinc finger and BTB domain containing 10 |
| ZFAND3 | zinc finger, AN1-type domain 3 |
| ZFHX3 | zinc finger homeobox 3 |
| ZFP36 | ZFP36 ring finger protein |
| ZNF10 | zinc finger protein 10 |
| ZNF276 | zinc finger protein 276 |
| ZNF426 | zinc finger protein 426 |
| ZNF442 | zinc finger protein 442 |
| ZNRD1-AS1 | ZNRD1 antisense RNA 1 |
