| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the leflunomide-6102 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACAN | aggrecan |
| ACRV1 | acrosomal vesicle protein 1 |
| ADAM29 | ADAM metallopeptidase domain 29 |
| ADAMTS7 | ADAM metallopeptidase with thrombospondin type 1 motif, 7 |
| ADGRB2 | adhesion G protein-coupled receptor B2 |
| ASMT | acetylserotonin O-methyltransferase |
| ATN1 | atrophin 1 |
| BCL2L10 | BCL2-like 10 (apoptosis facilitator) |
| BMP1 | bone morphogenetic protein 1 |
| C3 | complement component 3 |
| C4BPA | complement component 4 binding protein, alpha |
| CD1A | CD1a molecule |
| CD5 | CD5 molecule |
| CD79B | CD79b molecule, immunoglobulin-associated beta |
| CDIP1 | cell death-inducing p53 target 1 |
| CLGN | calmegin |
| CSF1 | colony stimulating factor 1 (macrophage) |
| CUL7 | cullin 7 |
| CXCL6 | chemokine (C-X-C motif) ligand 6 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 |
| CYLD | cylindromatosis (turban tumor syndrome) |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 |
| CYP2C9 | cytochrome P450, family 2, subfamily C, polypeptide 9 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 |
| DCLK2 | doublecortin-like kinase 2 |
| DENND5B | DENN/MADD domain containing 5B |
| DES | desmin |
| DGCR8 | DGCR8 microprocessor complex subunit |
| DPYSL4 | dihydropyrimidinase-like 4 |
| DUSP1 | dual specificity phosphatase 1 |
| ELAC2 | elaC ribonuclease Z 2 |
| ESR1 | estrogen receptor 1 |
| FUT9 | fucosyltransferase 9 (alpha (1,3) fucosyltransferase) |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) |
| GOLGA8A | golgin A8 family, member A |
| GPR135 | G protein-coupled receptor 135 |
| GSN | gelsolin |
| ICOSLG | inducible T-cell co-stimulator ligand |
| IDI2-AS1 | IDI2 antisense RNA 1 |
| IFFO1 | intermediate filament family orphan 1 |
| IGLJ3 | immunoglobulin lambda joining 3 |
| KCNH2 | potassium channel, voltage gated eag related subfamily H, member 2 |
| KCNN2 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2 |
| LAMC2 | laminin, gamma 2 |
| LARP4B | La ribonucleoprotein domain family, member 4B |
| LMTK1 | lemur tail kinase 1 |
| LRRC75B | leucine rich repeat containing 75B |
| LTBP4 | latent transforming growth factor beta binding protein 4 |
| MBD2 | methyl-CpG binding domain protein 2 |
| MNMIP1 | manchette microtubule inner protein 1 |
| MTMR8 | myotubularin related protein 8 |
| NOTCH4 | notch 4 |
| NOVA2 | neuro-oncological ventral antigen 2 |
| NRTN | neurturin |
| NUDT18 | nudix (nucleoside diphosphate linked moiety X)-type motif 18 |
| PAICS | phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase |
| PFKFB2 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 |
| PGLYRP4 | peptidoglycan recognition protein 4 |
| PPP2R3A | protein phosphatase 2, regulatory subunit B'', alpha |
| PPP5C | protein phosphatase 5, catalytic subunit |
| PRB1 | proline-rich protein BstNI subfamily 1 |
| PRTN3 | proteinase 3 |
| PTPN11 | protein tyrosine phosphatase, non-receptor type 11 |
| RND1 | Rho family GTPase 1 |
| RPS6KA6 | ribosomal protein S6 kinase, 90kDa, polypeptide 6 |
| RXRB | retinoid X receptor, beta |
| SARM1 | sterile alpha and TIR motif containing 1 |
| SEMA4G | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G |
| SIPA1 | signal-induced proliferation-associated 1 |
| SLC9A7 | solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7 |
| SMAD1 | SMAD family member 1 |
| SORBS3 | sorbin and SH3 domain containing 3 |
| SPOCK2 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 |
| SPRY4 | sprouty homolog 4 (Drosophila) |
| TAPBP | TAP binding protein (tapasin) |
| TBL2 | transducin (beta)-like 2 |
| TBX5 | T-box 5 |
| TENM4 | teneurin transmembrane protein 4 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 |
| TNFRSF25 | tumor necrosis factor receptor superfamily, member 25 |
| TNNT2 | troponin T type 2 (cardiac) |
| TOP3B | topoisomerase (DNA) III beta |
| TPSB2 | tryptase beta 2 (gene/pseudogene) |
| TPSG1 | tryptase gamma 1 |
| TRAFD1 | TRAF-type zinc finger domain containing 1 |
| TRIM3 | tripartite motif containing 3 |
| TTC38 | tetratricopeptide repeat domain 38 |
| UBE3A | ubiquitin protein ligase E3A |
| UCP1 | uncoupling protein 1 (mitochondrial, proton carrier) |
| UPK3A | uroplakin 3A |
| VCL | vinculin |
| VIPR1 | vasoactive intestinal peptide receptor 1 |
| WIPF1 | WAS/WASL interacting protein family, member 1 |
| ZEB1 | zinc finger E-box binding homeobox 1 |
| ZFP64 | ZFP64 zinc finger protein |
| ZNF280A | zinc finger protein 280A |
| ZNF695 | zinc finger protein 695 |
| Symbol | Name |
|---|---|
| ABI3BP | ABI family, member 3 (NESH) binding protein |
| ART1 | ADP-ribosyltransferase 1 |
| BAHCC1 | BAH domain and coiled-coil containing 1 |
| BGLAP | bone gamma-carboxyglutamate (gla) protein |
| BMP10 | bone morphogenetic protein 10 |
| C3ORF18 | chromosome 3 open reading frame 18 |
| C5AR2 | complement component 5a receptor 2 |
| CACNA2D2 | calcium channel, voltage-dependent, alpha 2/delta subunit 2 |
| CCRL2 | chemokine (C-C motif) receptor-like 2 |
| CD34 | CD34 molecule |
| CD79A | CD79a molecule, immunoglobulin-associated alpha |
| CFAP45 | cilia and flagella associated protein 45 |
| CHKB | choline kinase beta |
| CHRM3 | cholinergic receptor, muscarinic 3 |
| CHRNA9 | cholinergic receptor, nicotinic, alpha 9 (neuronal) |
| CLDN15 | claudin 15 |
| CLSPN | claspin |
| CORO7 | coronin 7 |
| CPA4 | carboxypeptidase A4 |
| CRIP1 | cysteine-rich protein 1 (intestinal) |
| CRYGC | crystallin, gamma C |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
| DUSP9 | dual specificity phosphatase 9 |
| ERCC2 | excision repair cross-complementation group 2 |
| FLJ11710 | uncharacterized protein FLJ11710 |
| GABRB2 | gamma-aminobutyric acid (GABA) A receptor, beta 2 |
| GMPR | guanosine monophosphate reductase |
| GNL3LP1 | guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1 |
| HAAO | 3-hydroxyanthranilate 3,4-dioxygenase |
| HAO2 | hydroxyacid oxidase 2 (long chain) |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 |
| HIST1H3E | histone cluster 1, H3e |
| HIST1H4D | histone cluster 1, H4d |
| HIST1H4F | histone cluster 1, H4f |
| HOXC8 | homeobox C8 |
| IFNA14 | interferon, alpha 14 |
| IL22 | interleukin 22 |
| IQCC | IQ motif containing C |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) |
| ITIH2 | inter-alpha-trypsin inhibitor heavy chain 2 |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like |
| KIAA0754 | KIAA0754 |
| KIAA1456 | KIAA1456 |
| KLHL21 | kelch-like family member 21 |
| LENEP | lens epithelial protein |
| LINC01587 | long intergenic non-protein coding RNA 1587 |
| LRRC6 | leucine rich repeat containing 6 |
| LTBP2 | latent transforming growth factor beta binding protein 2 |
| LTC4S | leukotriene C4 synthase |
| MADCAM1 | mucosal vascular addressin cell adhesion molecule 1 |
| MMP3 | matrix metallopeptidase 3 |
| NDUFAF5 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 5 |
| NLGN1 | neuroligin 1 |
| NME5 | NME/NM23 family member 5 |
| NPIPB15 | nuclear pore complex interacting protein family, member B15 |
| OR2F1 | olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene) |
| PIM1 | Pim-1 proto-oncogene, serine/threonine kinase |
| PLA2G3 | phospholipase A2, group III |
| PMCHL1 | pro-melanin-concentrating hormone-like 1, pseudogene |
| PQLC2 | PQ loop repeat containing 2 |
| PRRG4 | proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) |
| PTRF | polymerase I and transcript release factor |
| QPCTL | glutaminyl-peptide cyclotransferase-like |
| RAB40AL | RAB40A, member RAS oncogene family-like |
| RAB40C | RAB40C, member RAS oncogene family |
| RAPSN | receptor-associated protein of the synapse |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 |
| RFXAP | regulatory factor X-associated protein |
| RGCC | regulator of cell cycle |
| RHBDD3 | rhomboid domain containing 3 |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase |
| ROBO3 | roundabout, axon guidance receptor, homolog 3 (Drosophila) |
| RPL10L | ribosomal protein L10-like |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
| SGCG | sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) |
| SKI | SKI proto-oncogene |
| SLC34A2 | solute carrier family 34 (type II sodium/phosphate cotransporter), member 2 |
| SPRR1B | small proline-rich protein 1B |
| STAB2 | stabilin 2 |
| STAG3 | stromal antigen 3 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) |
| TAOK1 | TAO kinase 1 |
| TCTN1 | tectonic family member 1 |
| TEX15 | testis expressed 15 |
| TFF2 | trefoil factor 2 |
| TGFBR1 | transforming growth factor, beta receptor 1 |
| TM6SF1 | transmembrane 6 superfamily member 1 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) |
| TRIM21 | tripartite motif containing 21 |
| TRIM36 | tripartite motif containing 36 |
| TRPM4 | transient receptor potential cation channel, subfamily M, member 4 |
| VIM | vimentin |
| WNT10B | wingless-type MMTV integration site family, member 10B |
| YIF1B | Yip1 interacting factor homolog B (S. cerevisiae) |
| ZNF571 | zinc finger protein 571 |
| ZNF747 | zinc finger protein 747 |
| ZNF770 | zinc finger protein 770 |
| ZNF804A | zinc finger protein 804A |
