leg Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description A limb of an animal used especially for supporting the body and for walking. (BRENDA Tissue and Enzyme Source Ontology, BTO_0000721)
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Genes

61 genes co-occuring with the biological term leg in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ACE angiotensin I converting enzyme
ACKR1 atypical chemokine receptor 1 (Duffy blood group)
ACTN3 actinin, alpha 3 (gene/pseudogene)
ADRA2B adrenoceptor alpha 2B
AMPH amphiphysin
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide
ATP4B ATPase, H+/K+ exchanging, beta polypeptide
B2M beta-2-microglobulin
BCL6 B-cell CLL/lymphoma 6
BTBD9 BTB (POZ) domain containing 9
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CDKN2A cyclin-dependent kinase inhibitor 2A
COL12A1 collagen, type XII, alpha 1
COL3A1 collagen, type III, alpha 1
COL6A1 collagen, type VI, alpha 1
CXCL12 chemokine (C-X-C motif) ligand 12
CXCR4 chemokine (C-X-C motif) receptor 4
DARS aspartyl-tRNA synthetase
DEFA1 defensin, alpha 1
DEFA3 defensin, alpha 3, neutrophil-specific
DRD2 dopamine receptor D2
EDN1 endothelin 1
EPO erythropoietin
F13A1 coagulation factor XIII, A1 polypeptide
F2 coagulation factor II (thrombin)
F5 coagulation factor V (proaccelerin, labile factor)
FOXP1 forkhead box P1
GJA1 gap junction protein, alpha 1, 43kDa
GNE glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
HFE hemochromatosis
IGF1 insulin-like growth factor 1 (somatomedin C)
IGH immunoglobulin heavy locus
IL1B interleukin 1, beta
IL6 interleukin 6
IRF4 interferon regulatory factor 4
ITGAV integrin, alpha V
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
LEPR leptin receptor
LMNA lamin A/C
MAP2K5 mitogen-activated protein kinase kinase 5
MEIS1 Meis homeobox 1
MET MET proto-oncogene, receptor tyrosine kinase
MPZL1 myelin protein zero-like 1
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MYD88 myeloid differentiation primary response 88
NOS3 nitric oxide synthase 3 (endothelial cell)
NPPA natriuretic peptide A
NPPB natriuretic peptide B
NRP1 neuropilin 1
OSM oncostatin M
PARK2 parkin RBR E3 ubiquitin protein ligase
PTPRD protein tyrosine phosphatase, receptor type, D
SDC4 syndecan 4
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
TBC1D4 TBC1 domain family, member 4
TGFB1 transforming growth factor, beta 1
TNF tumor necrosis factor
TOX3 TOX high mobility group box family member 3
TPM2 tropomyosin 2 (beta)
VEGFA vascular endothelial growth factor A