legionnaires' disease Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores
Category disease or phenotype associations
Type disease
Description A legionellosis that is characterized by severe form of infection producing pneumonia. Symptoms include fever, chills, and cough. (Human Disease Ontology, DOID_10457)
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Genes

122 genes co-occuring with the disease legionnaires' disease in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
NLRC4 NLR family, CARD domain containing 4 1.59206
RAB6A RAB6A, member RAS oncogene family 1.36291
RAB1A RAB1A, member RAS oncogene family 1.32716
CANX calnexin 1.25645
SUMF2 sulfatase modifying factor 2 1.1841
CLPP caseinolytic mitochondrial matrix peptidase proteolytic subunit 1.13585
YKT6 YKT6 v-SNARE homolog (S. cerevisiae) 1.03409
SPATA19 spermatogenesis associated 19 1.0265
NLRC5 NLR family, CARD domain containing 5 1.01849
CARD17 caspase recruitment domain family, member 17 1.00246
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha 0.992752
RAN RAN, member RAS oncogene family 0.9696
TLR5 toll-like receptor 5 0.958287
ANKLE1 ankyrin repeat and LEM domain containing 1 0.937874
ANK2 ankyrin 2, neuronal 0.937459
FKBP1A FK506 binding protein 1A, 12kDa 0.920911
RCE1 Ras converting CAAX endopeptidase 1 0.905675
VPS29 vacuolar protein sorting 29 homolog (S. cerevisiae) 0.893359
MYD88 myeloid differentiation primary response 88 0.877376
CASS4 Cas scaffolding protein family member 4 0.812232
RAB1B RAB1B, member RAS oncogene family 0.81018
RANBP1 RAN binding protein 1 0.803616
RAB8A RAB8A, member RAS oncogene family 0.792541
KCNIP4 Kv channel interacting protein 4 0.759008
NAIP NLR family, apoptosis inhibitory protein 0.741923
PDLIM5 PDZ and LIM domain 5 0.73746
MORF4 mortality factor 4 (pseudogene) 0.728143
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 0.718039
MARCO macrophage receptor with collagenous structure 0.718039
GCAT glycine C-acetyltransferase 0.707559
LAMP1 lysosomal-associated membrane protein 1 0.692697
YBX3 Y box binding protein 3 0.692296
ICMT isoprenylcysteine carboxyl methyltransferase 0.674713
COPA coatomer protein complex, subunit alpha 0.670732
FKBP2 FK506 binding protein 2, 13kDa 0.652089
NOD1 nucleotide-binding oligomerization domain containing 1 0.642221
BIN3 bridging integrator 3 0.637495
RNF34 ring finger protein 34, E3 ubiquitin protein ligase 0.6003
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha 0.59952
HAND1 heart and neural crest derivatives expressed 1 0.588612
HSPD1 heat shock 60kDa protein 1 (chaperonin) 0.578106
SKP1 S-phase kinase-associated protein 1 0.569163
PYCARD PYD and CARD domain containing 0.534248
SEL1L sel-1 suppressor of lin-12-like (C. elegans) 0.528835
ATF1 activating transcription factor 1 0.51842
HDAC5 histone deacetylase 5 0.517265
ARF1 ADP-ribosylation factor 1 0.51188
PXN paxillin 0.487407
SFTPA1 surfactant protein A1 0.480566
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 0.461639
CS citrate synthase 0.450324
EEA1 early endosome antigen 1 0.442042
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 0.42589
GOT1 glutamic-oxaloacetic transaminase 1, soluble 0.419892
TMPRSS15 transmembrane protease, serine 15 0.409787
RHAG Rh-associated glycoprotein 0.402692
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial 0.391513
TLR4 toll-like receptor 4 0.390025
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha 0.389281
PIDD1 p53-induced death domain protein 1 0.388909
PMM2 phosphomannomutase 2 0.385565
PTPN3 protein tyrosine phosphatase, non-receptor type 3 0.382594
WNT10A wingless-type MMTV integration site family, member 10A 0.379626
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5 0.367779
TLR6 toll-like receptor 6 0.359289
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 0.355604
TLR2 toll-like receptor 2 0.348614
GPR162 G protein-coupled receptor 162 0.348246
TFRC transferrin receptor 0.347879
PRDX6 peroxiredoxin 6 0.344574
GP2 glycoprotein 2 (zymogen granule membrane) 0.340906
TXNL4B thioredoxin-like 4B 0.339073
M6PR mannose-6-phosphate receptor (cation dependent) 0.334681
OCRL oculocerebrorenal syndrome of Lowe 0.332121
WARS tryptophanyl-tRNA synthetase 0.320454
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase) 0.319726
DDX19B DEAD (Asp-Glu-Ala-Asp) box polypeptide 19B 0.307757
CRP C-reactive protein, pentraxin-related 0.288668
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1 0.28616
CD4 CD4 molecule 0.285086
SLC6A1 solute carrier family 6 (neurotransmitter transporter), member 1 0.283655
JUND jun D proto-oncogene 0.275445
LBR lamin B receptor 0.274376
CAT catalase 0.264431
SEMG1 semenogelin I 0.252422
APOH apolipoprotein H (beta-2-glycoprotein I) 0.248554
CCNE1 cyclin E1 0.24715
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta 0.240847
CR1 complement component (3b/4b) receptor 1 (Knops blood group) 0.239101
HAND2 heart and neural crest derivatives expressed 2 0.218034
ALPPL2 alkaline phosphatase, placental-like 2 0.212271
ALPP alkaline phosphatase, placental 0.211934
ALPL alkaline phosphatase, liver/bone/kidney 0.211597
LAMP2 lysosomal-associated membrane protein 2 0.210925
WAPAL wings apart-like homolog (Drosophila) 0.208579
HIST1H4D histone cluster 1, H4d 0.205254
HIST1H4A histone cluster 1, H4a 0.205254
HIST1H4E histone cluster 1, H4e 0.205254
HIST1H4C histone cluster 1, H4c 0.205254
HIST1H4B histone cluster 1, H4b 0.205254
HIST1H4K histone cluster 1, H4k 0.205254
HIST1H4J histone cluster 1, H4j 0.205254
HIST1H4F histone cluster 1, H4f 0.205254
HIST2H4B histone cluster 2, H4b 0.205254
HIST1H4H histone cluster 1, H4h 0.205254
HIST1H4I histone cluster 1, H4i 0.205254
TLR1 toll-like receptor 1 0.204923
HIST2H4A histone cluster 2, H4a 0.204593
HIST1H4L histone cluster 1, H4l 0.203275
HIST4H4 histone cluster 4, H4 0.202946
CX3CL1 chemokine (C-X3-C motif) ligand 1 0.197742
CASP7 caspase 7, apoptosis-related cysteine peptidase 0.189859
SQSTM1 sequestosome 1 0.189551
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) 0.188022
IRF3 interferon regulatory factor 3 0.183541
PI3 peptidase inhibitor 3, skin-derived 0.181222
SLC35A2 solute carrier family 35 (UDP-galactose transporter), member A2 0.179239
LGALS7 lectin, galactoside-binding, soluble, 7 0.171785
PTGES prostaglandin E synthase 0.171036
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 0.166995
HTRA1 HtrA serine peptidase 1 0.163317
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin) 0.162707