lens fiber cell differentiation Gene Set

Dataset GO Biological Process Annotations
Category structural or functional annotations
Type biological process
Description The process in which a relatively unspecialized cell acquires specialized features of a lens fiber cell, any of the elongated, tightly packed cells that make up the bulk of the mature lens in the camera-type eye. The cytoplasm of a lens fiber cell is devoid of most intracellular organelles including the cell nucleus, and contains primarily crystallins, a group of water-soluble proteins expressed in vary large quantities. (Gene Ontology, GO_0070306)
External Link http://amigo.geneontology.org/amigo/term/GO:0070306
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12 genes participating in the lens fiber cell differentiation biological process from the curated GO Biological Process Annotations dataset.

Symbol Name
CRYGD crystallin, gamma D
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
NF2 neurofibromin 2 (merlin)
NTRK3 neurotrophic tyrosine kinase, receptor, type 3
PITX3 paired-like homeodomain 3
SIX3 SIX homeobox 3
SKIL SKI-like proto-oncogene
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SMAD3 SMAD family member 3
TDRD7 tudor domain containing 7
TGFB1 transforming growth factor, beta 1