lens Gene Set

Dataset TISSUES Text-mining Tissue Protein Expression Evidence Scores
Category structural or functional annotations
Type tissue
Description A highly transparent biconvex lens-shaped or nearly spherical body in the eye that focuses light rays (as upon the retina). (BRENDA Tissue and Enzyme Source Ontology, BTO_0000723)
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Genes

743 proteins co-occuring with the tissue lens in abstracts of biomedical publications from the TISSUES Text-mining Tissue Protein Expression Evidence Scores dataset.

Symbol Name Standardized Value
CRYAA crystallin, alpha A 2.98218
CRYGS crystallin, gamma S 2.94728
MIP major intrinsic protein of lens fiber 2.94526
GJA8 gap junction protein, alpha 8, 50kDa 2.30633
BFSP2 beaded filament structural protein 2, phakinin 2.24803
GJA3 gap junction protein, alpha 3, 46kDa 2.22514
CRYAB crystallin, alpha B 2.19875
CRYBB1 crystallin, beta B1 2.09738
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) 1.93416
FOXE3 forkhead box E3 1.82094
CRYBB2 crystallin, beta B2 1.81992
LIM2 lens intrinsic membrane protein 2, 19kDa 1.8189
PSIP1 PC4 and SFRS1 interacting protein 1 1.76024
CRYGC crystallin, gamma C 1.7144
ELANE elastase, neutrophil expressed 1.70346
CRYGD crystallin, gamma D 1.61559
CRYBA2 crystallin, beta A2 1.60614
PAX6 paired box 6 1.58683
LAMA3 laminin, alpha 3 1.58535
GJA1 gap junction protein, alpha 1, 43kDa 1.50386
FGF1 fibroblast growth factor 1 (acidic) 1.47615
FN1 fibronectin 1 1.46868
CRYGB crystallin, gamma B 1.46775
DNAH8 dynein, axonemal, heavy chain 8 1.44172
FYCO1 FYVE and coiled-coil domain containing 1 1.43662
TGFB1 transforming growth factor, beta 1 1.43246
TGFB2 transforming growth factor, beta 2 1.43107
FBN1 fibrillin 1 1.33048
FGF2 fibroblast growth factor 2 (basic) 1.3192
DNASE2B deoxyribonuclease II beta 1.31424
CRYBA1 crystallin, beta A1 1.28098
HSF4 heat shock transcription factor 4 1.2394
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2) 1.23539
CDH2 cadherin 2, type 1, N-cadherin (neuronal) 1.22559
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog 1.2238
VSX2 visual system homeobox 2 1.15983
NID1 nidogen 1 1.15894
LOXL1 lysyl oxidase-like 1 1.14653
MSRB1 methionine sulfoxide reductase B1 1.1452
CASP3 caspase 3, apoptosis-related cysteine peptidase 1.0603
OPTC opticin 1.02469
PROX1 prospero homeobox 1 1.00807
PITX3 paired-like homeodomain 3 1.00327
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1 0.994989
PCNA proliferating cell nuclear antigen 0.994119
CAT catalase 0.974149
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.970686
GJC1 gap junction protein, gamma 1, 45kDa 0.958154
CRYBB3 crystallin, beta B3 0.954271
PRDX6 peroxiredoxin 6 0.953409
GLRX2 glutaredoxin 2 0.950823
GSR glutathione reductase 0.946947
SOX1 SRY (sex determining region Y)-box 1 0.941785
PEX19 peroxisomal biogenesis factor 19 0.936629
LGSN lengsin, lens protein with glutamine synthetase domain 0.934911
TJP1 tight junction protein 1 0.929335
NRL neural retina leucine zipper 0.92291
SMAD2 SMAD family member 2 0.919916
CALM3 calmodulin 3 (phosphorylase kinase, delta) 0.916069
CALM2 calmodulin 2 (phosphorylase kinase, delta) 0.916069
CALM1 calmodulin 1 (phosphorylase kinase, delta) 0.914788
TBK1 TANK-binding kinase 1 0.912653
DES desmin 0.912226
IGF1 insulin-like growth factor 1 (somatomedin C) 0.907961
FTL ferritin, light polypeptide 0.906682
DNTT DNA nucleotidylexotransferase 0.905404
CDC34 cell division cycle 34 0.89562
PRIMPOL primase and polymerase (DNA-directed) 0.893921
AKAP2 A kinase (PRKA) anchor protein 2 0.87782
LENEP lens epithelial protein 0.876974
BAX BCL2-associated X protein 0.871905
MYOC myocilin, trabecular meshwork inducible glucocorticoid response 0.867263
CRYBA4 crystallin, beta A4 0.851686
ATP2B2 ATPase, Ca++ transporting, plasma membrane 2 0.846225
GAPDH glyceraldehyde-3-phosphate dehydrogenase 0.845805
TMEM114 transmembrane protein 114 0.841608
CAPN2 calpain 2, (m/II) large subunit 0.836995
RHO rhodopsin 0.831547
GPX1 glutathione peroxidase 1 0.830291
EPHA2 EPH receptor A2 0.82736
LTBP1 latent transforming growth factor beta binding protein 1 0.81565
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase 0.809803
HSF2 heat shock transcription factor 2 0.794375
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.793126
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial 0.781478
CRYGA crystallin, gamma A 0.779401
MRGPRX3 MAS-related GPR, member X3 0.773589
MMP2 matrix metallopeptidase 2 0.773174
SOD2 superoxide dismutase 2, mitochondrial 0.77193
AQP5 aquaporin 5 0.77193
USP35 ubiquitin specific peptidase 35 0.7711
LAP3 leucine aminopeptidase 3 0.77027
SUOX sulfite oxidase 0.769855
INS insulin 0.769027
FGFR1 fibroblast growth factor receptor 1 0.767368
SORD sorbitol dehydrogenase 0.760328
FTH1 ferritin, heavy polypeptide 1 0.755777
NPRL3 nitrogen permease regulator-like 3 (S. cerevisiae) 0.743801
CRYZ crystallin, zeta (quinone reductase) 0.739678
ANXA5 annexin A5 0.739678
GPX5 glutathione peroxidase 5 0.732677
DNM2 dynamin 2 0.719113
MFRP membrane frizzled-related protein 0.717472
GPX4 glutathione peroxidase 4 0.713779
GFAP glial fibrillary acidic protein 0.70927
AQP1 aquaporin 1 (Colton blood group) 0.704764
UBE2A ubiquitin-conjugating enzyme E2A 0.703127
NDUFA12 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12 0.698625
UBE2D2 ubiquitin-conjugating enzyme E2D 2 0.698216
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 0.690859
MAP1LC3B2 microtubule-associated protein 1 light chain 3 beta 2 0.689634
NHS Nance-Horan syndrome (congenital cataracts and dental anomalies) 0.687592
ATP11A ATPase, class VI, type 11A 0.687184
TMOD1 tropomodulin 1 0.685143
SMAD4 SMAD family member 4 0.683103
JUN jun proto-oncogene 0.665588
ALB albumin 0.654618
CLCN3 chloride channel, voltage-sensitive 3 0.653807
ILK integrin-linked kinase 0.652589
SRP68 signal recognition particle 68kDa 0.642858
ATP2B3 ATPase, Ca++ transporting, plasma membrane 3 0.642454
SLC12A7 solute carrier family 12 (potassium/chloride transporter), member 7 0.638404
HK1 hexokinase 1 0.63638
MFAP2 microfibrillar-associated protein 2 0.633953
RCVRN recoverin 0.633549
TGFB3 transforming growth factor, beta 3 0.633144
HLA-DQB2 major histocompatibility complex, class II, DQ beta 2 0.62991
CA2 carbonic anhydrase II 0.628697
MLEC malectin 0.6182
FBN2 fibrillin 2 0.617796
SFRP2 secreted frizzled-related protein 2 0.609735
GSTA4 glutathione S-transferase alpha 4 0.608527
WNT8B wingless-type MMTV integration site family, member 8B 0.607722
CD44 CD44 molecule (Indian blood group) 0.607319
ADAM9 ADAM metallopeptidase domain 9 0.604502
SIX3 SIX homeobox 3 0.602088
PTRH2 peptidyl-tRNA hydrolase 2 0.59646
SLC16A12 solute carrier family 16, member 12 0.595656
CPNE6 copine VI (neuronal) 0.592845
KRT8 keratin 8, type II 0.588832
B3GAT1 beta-1,3-glucuronyltransferase 1 0.584823
GSTA2 glutathione S-transferase alpha 2 0.580417
TF transferrin 0.578416
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B 0.576816
GSTA1 glutathione S-transferase alpha 1 0.576015
VIM vimentin 0.575216
E2F5 E2F transcription factor 5, p130-binding 0.574816
RLBP1 retinaldehyde binding protein 1 0.572818
LTBP2 latent transforming growth factor beta binding protein 2 0.571219
TXN thioredoxin 0.57082
PANX1 pannexin 1 0.568823
GALK2 galactokinase 2 0.568424
SLC23A1 solute carrier family 23 (ascorbic acid transporter), member 1 0.567626
SMAD3 SMAD family member 3 0.56603
PROS1 protein S (alpha) 0.56603
CAV1 caveolin 1, caveolae protein, 22kDa 0.564035
GSS glutathione synthetase 0.563238
CRYGN crystallin, gamma N 0.563238
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 0.562042
EPB41 erythrocyte membrane protein band 4.1 0.555671
AQP4 aquaporin 4 0.55249
GSTA3 glutathione S-transferase alpha 3 0.551298
BFSP1 beaded filament structural protein 1, filensin 0.549709
RAET1L retinoic acid early transcript 1L 0.547326
HMGA1 high mobility group AT-hook 1 0.546929
ANO8 anoctamin 8 0.546533
SAG S-antigen; retina and pineal gland (arrestin) 0.545342
COCH cochlin 0.540585
PSMD6 proteasome (prosome, macropain) 26S subunit, non-ATPase, 6 0.540188
UBE2G2 ubiquitin-conjugating enzyme E2G 2 0.539793
VCL vinculin 0.539
E2F2 E2F transcription factor 2 0.533065
BEST2 bestrophin 2 0.533065
PALMD palmdelphin 0.531879
PVRL1 poliovirus receptor-related 1 (herpesvirus entry mediator C) 0.529113
UBE2B ubiquitin-conjugating enzyme E2B 0.525955
MMP9 matrix metallopeptidase 9 0.523982
MSRA methionine sulfoxide reductase A 0.523588
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen) 0.520041
NXNL1 nucleoredoxin-like 1 0.518072
GLB1 galactosidase, beta 1 0.51571
VSX1 visual system homeobox 1 0.515317
PRX periaxin 0.51453
BMP7 bone morphogenetic protein 7 0.510599
UBE2H ubiquitin-conjugating enzyme E2H 0.510599
GPR137B G protein-coupled receptor 137B 0.50942
REST RE1-silencing transcription factor 0.50942
ATF6 activating transcription factor 6 0.506279
PEX7 peroxisomal biogenesis factor 7 0.505887
ADCY2 adenylate cyclase 2 (brain) 0.503926
FOS FBJ murine osteosarcoma viral oncogene homolog 0.497266
AQP3 aquaporin 3 (Gill blood group) 0.497266
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila) 0.497266
COL4A5 collagen, type IV, alpha 5 0.494528
KRT12 keratin 12, type I 0.493745
KEAP1 kelch-like ECH-associated protein 1 0.493354
NES nestin 0.489838
FGFR2 fibroblast growth factor receptor 2 0.489057
WNT6 wingless-type MMTV integration site family, member 6 0.489057
PHRF1 PHD and ring finger domains 1 0.486716
BCL2 B-cell CLL/lymphoma 2 0.485156
G6PD glucose-6-phosphate dehydrogenase 0.484376
ADAMTS17 ADAM metallopeptidase with thrombospondin type 1 motif, 17 0.483206
CARD17 caspase recruitment domain family, member 17 0.481648
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila) 0.48087
PRDX3 peroxiredoxin 3 0.478923
CDK5 cyclin-dependent kinase 5 0.476589
HSPA4 heat shock 70kDa protein 4 0.475423
DPP7 dipeptidyl-peptidase 7 0.475423
TERT telomerase reverse transcriptase 0.473092
CAST calpastatin 0.470763
FOXC1 forkhead box C1 0.466498
METTL3 methyltransferase like 3 0.466498
DMPK dystrophia myotonica-protein kinase 0.464561
ENO2 enolase 2 (gamma, neuronal) 0.464174
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 0.464174
P3H2 prolyl 3-hydroxylase 2 0.463787
TP53 tumor protein p53 0.462626
COL8A2 collagen, type VIII, alpha 2 0.461465
HMGN3 high mobility group nucleosomal binding domain 3 0.455284
COL4A1 collagen, type IV, alpha 1 0.454898
FAM46D family with sequence similarity 46, member D 0.452198
TBATA thymus, brain and testes associated 0.446422
GLRX glutaredoxin (thioltransferase) 0.442578
CTRL chymotrypsin-like 0.441042
CIB2 calcium and integrin binding family member 2 0.440274
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 0.436055
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1 0.435672
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.435289
TPM1 tropomyosin 1 (alpha) 0.432608
CTSS cathepsin S 0.428401
ATP2A3 ATPase, Ca++ transporting, ubiquitous 0.427636
AHNAK AHNAK nucleoprotein 0.42649
NOTCH1 notch 1 0.425726
NOG noggin 0.425344
TRDMT1 tRNA aspartic acid methyltransferase 1 0.422292
MKLN1 muskelin 1, intracellular mediator containing kelch motifs 0.422292
TNC tenascin C 0.42191
CAPN3 calpain 3, (p94) 0.414293
NQO1 NAD(P)H dehydrogenase, quinone 1 0.413532
GGTLC2 gamma-glutamyltransferase light chain 2 0.413151
VIP vasoactive intestinal peptide 0.411631
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) 0.410111
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 0.408972
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like 0.407073
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 0.406694
ADAMTS10 ADAM metallopeptidase with thrombospondin type 1 motif, 10 0.405176
ATF4 activating transcription factor 4 0.404797
CETN3 centrin, EF-hand protein, 3 0.404418
DPT dermatopontin 0.401765
CP ceruloplasmin (ferroxidase) 0.401386
CCDC80 coiled-coil domain containing 80 0.401007
NKG7 natural killer cell granule protein 7 0.398735
CPSF6 cleavage and polyadenylation specific factor 6, 68kDa 0.3976
TDRD7 tudor domain containing 7 0.397222
SRC SRC proto-oncogene, non-receptor tyrosine kinase 0.392686
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1 0.388535
BCAP29 B-cell receptor-associated protein 29 0.388158
PLEKHA7 pleckstrin homology domain containing, family A member 7 0.387027
TKT transketolase 0.384013
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1 0.382884
EFNA3 ephrin-A3 0.381379
MSRB3 methionine sulfoxide reductase B3 0.378748
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1 0.378748
PART1 prostate androgen-regulated transcript 1 (non-protein coding) 0.375743
CAPN10 calpain 10 0.374243
ACPP acid phosphatase, prostate 0.374243
AXL AXL receptor tyrosine kinase 0.373868
RPL21 ribosomal protein L21 0.371619
SPRY2 sprouty homolog 2 (Drosophila) 0.370496
TET1 tet methylcytosine dioxygenase 1 0.369747
ADCY10 adenylate cyclase 10 (soluble) 0.364886
COL18A1 collagen, type XVIII, alpha 1 0.363393
ASL argininosuccinate lyase 0.361527
PPL periplakin 0.361155
SOX3 SRY (sex determining region Y)-box 3 0.358919
LUM lumican 0.358546
ANO3 anoctamin 3 0.357058
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1 0.353712
OCLN occludin 0.352969
PTMS parathymosin 0.352969
SRP72 signal recognition particle 72kDa 0.351856
ETFB electron-transfer-flavoprotein, beta polypeptide 0.350372
SLC12A6 solute carrier family 12 (potassium/chloride transporter), member 6 0.350001
PTBP2 polypyrimidine tract binding protein 2 0.34963
SEBOX SEBOX homeobox 0.347038
CBS cystathionine-beta-synthase 0.345928
TNF tumor necrosis factor 0.345928
FOXP2 forkhead box P2 0.345558
EAF2 ELL associated factor 2 0.345558
KLK15 kallikrein-related peptidase 15 0.344818
RNGTT RNA guanylyltransferase and 5'-phosphatase 0.34371
HIVEP1 human immunodeficiency virus type I enhancer binding protein 1 0.342233
SDC2 syndecan 2 0.341495
C11ORF40 chromosome 11 open reading frame 40 0.341126
ACTG1 actin gamma 1 0.340757
MRPL13 mitochondrial ribosomal protein L13 0.340757
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3 0.340019
KRT3 keratin 3, type II 0.339282
DDX39A DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A 0.338545
MAB21L1 mab-21-like 1 (C. elegans) 0.337072
TGM2 transglutaminase 2 0.336336
CELF1 CUGBP, Elav-like family member 1 0.335233
PARP1 poly (ADP-ribose) polymerase 1 0.333763
FGFR3 fibroblast growth factor receptor 3 0.331927
MNX1 motor neuron and pancreas homeobox 1 0.331927
TXNRD1 thioredoxin reductase 1 0.33156
AGPS alkylglycerone phosphate synthase 0.330094
ANK2 ankyrin 2, neuronal 0.328628
UNC45B unc-45 homolog B (C. elegans) 0.32753
GPR84 G protein-coupled receptor 84 0.325335
NOTCH2NL notch 2 N-terminal like 0.325335
EDN1 endothelin 1 0.324605
NR2E3 nuclear receptor subfamily 2, group E, member 3 0.323144
NOTCH2 notch 2 0.322414
IPO5 importin 5 0.32132
ENO1 enolase 1, (alpha) 0.31877
UBE2D4 ubiquitin-conjugating enzyme E2D 4 (putative) 0.316951
PPP2R1B protein phosphatase 2, regulatory subunit A, beta 0.316951
MUT methylmalonyl CoA mutase 0.314046
HPGDS hematopoietic prostaglandin D synthase 0.31187
SHROOM3 shroom family member 3 0.31187
MLXIPL MLX interacting protein-like 0.31187
CTGF connective tissue growth factor 0.310783
NPR3 natriuretic peptide receptor 3 0.310421
SNPH syntaphilin 0.307889
CHKB choline kinase beta 0.307167
IRF8 interferon regulatory factor 8 0.305361
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1 0.305361
WIPI1 WD repeat domain, phosphoinositide interacting 1 0.305361
MAF1 MAF1 homolog (S. cerevisiae) 0.302838
ACTB actin, beta 0.301758
CAPRIN2 caprin family member 2 0.30032
CHMP4B charged multivesicular body protein 4B 0.299242
KIAA0586 KIAA0586 0.299242
SEPT8 septin 8 0.299242
PTGER4 prostaglandin E receptor 4 (subtype EP4) 0.292079
UBE2E1 ubiquitin-conjugating enzyme E2E 1 0.291722
SLC25A29 solute carrier family 25 (mitochondrial carnitine/acylcarnitine carrier), member 29 0.291365
STAU1 staufen double-stranded RNA binding protein 1 0.290652
UBE2T ubiquitin-conjugating enzyme E2T 0.289939
MSRB2 methionine sulfoxide reductase B2 0.289582
MGST1 microsomal glutathione S-transferase 1 0.289582
RHOB ras homolog family member B 0.288514
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4 0.287447
APOD apolipoprotein D 0.287092
SDC3 syndecan 3 0.284253
UBE2G1 ubiquitin-conjugating enzyme E2G 1 0.28107
NLRP4 NLR family, pyrin domain containing 4 0.277549
NIN ninein (GSK3B interacting protein) 0.276495
EZR ezrin 0.275794
CREB1 cAMP responsive element binding protein 1 0.274394
GPR18 G protein-coupled receptor 18 0.274394
AQP2 aquaporin 2 (collecting duct) 0.274394
GCNT4 glucosaminyl (N-acetyl) transferase 4, core 2 0.273696
MBNL2 muscleblind-like splicing regulator 2 0.270561
TGFBR1 transforming growth factor, beta receptor 1 0.269521
P2RY2 purinergic receptor P2Y, G-protein coupled, 2 0.269174
DNMT1 DNA (cytosine-5-)-methyltransferase 1 0.268828
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.268482
UBE2E3 ubiquitin-conjugating enzyme E2E 3 0.266413
CASP9 caspase 9, apoptosis-related cysteine peptidase 0.265725
ANK1 ankyrin 1, erythrocytic 0.264696
GSTM3 glutathione S-transferase mu 3 (brain) 0.262645
JAG1 jagged 1 0.261284
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase 0.261284
AQP12A aquaporin 12A 0.260267
PPP2R2B protein phosphatase 2, regulatory subunit B, beta 0.259591
TTR transthyretin 0.257237
CCL15 chemokine (C-C motif) ligand 15 0.256234
IDO1 indoleamine 2,3-dioxygenase 1 0.255234
STAT1 signal transducer and activator of transcription 1, 91kDa 0.254902
GALK1 galactokinase 1 0.254239
PXN paxillin 0.253578
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 0.252919
ERCC2 excision repair cross-complementation group 2 0.252919
ARHGEF25 Rho guanine nucleotide exchange factor (GEF) 25 0.251606
C1QTNF5 C1q and tumor necrosis factor related protein 5 0.249977
GRK1 G protein-coupled receptor kinase 1 0.247719
FGF4 fibroblast growth factor 4 0.24676
CPE carboxypeptidase E 0.245491
CASP6 caspase 6, apoptosis-related cysteine peptidase 0.24486
ATG4B autophagy related 4B, cysteine peptidase 0.243918
JUP junction plakoglobin 0.242983
SLC1A6 solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6 0.241438
CA4 carbonic anhydrase IV 0.24052
MKL2 MKL/myocardin-like 2 0.239307
CSN1S1 casein alpha s1 0.239307
OPN4 opsin 4 0.239007
NCK2 NCK adaptor protein 2 0.238406
THBS1 thrombospondin 1 0.238108
BOC BOC cell adhesion associated, oncogene regulated 0.237216
PASK PAS domain containing serine/threonine kinase 0.235748
ITGB4 integrin, beta 4 0.235167
BCAR1 breast cancer anti-estrogen resistance 1 0.234016
ISL2 ISL LIM homeobox 2 0.232317
MIOX myo-inositol oxygenase 0.229839
NPPC natriuretic peptide C 0.228497
CCNDBP1 cyclin D-type binding-protein 1 0.228497
MGST2 microsomal glutathione S-transferase 2 0.228234
SCG2 secretogranin II 0.228234
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha 0.227707
KDM5B lysine (K)-specific demethylase 5B 0.227445
CDKN2A cyclin-dependent kinase inhibitor 2A 0.226667
MGAM maltase-glucoamylase 0.226155
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 0.224645
CRYM crystallin, mu 0.224398
P3H1 prolyl 3-hydroxylase 1 0.224398
PTCH1 patched 1 0.22415
H2AFX H2A histone family, member X 0.223177
HMGN1 high mobility group nucleosome binding domain 1 0.222699
E2F3 E2F transcription factor 3 0.222224
CYP4V2 cytochrome P450, family 4, subfamily V, polypeptide 2 0.221989
AQP7 aquaporin 7 0.221755
MYLK myosin light chain kinase 0.220378
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2 0.219928
NDST2 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2 0.219928
IL1A interleukin 1, alpha 0.219264
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6 0.219047
MS4A3 membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) 0.218398
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like) 0.218186
ALDH7A1 aldehyde dehydrogenase 7 family, member A1 0.217554
MMP3 matrix metallopeptidase 3 0.216933
CCND1 cyclin D1 0.216528
WNT7B wingless-type MMTV integration site family, member 7B 0.216325
NCOA6 nuclear receptor coactivator 6 0.215147
PSMB5 proteasome (prosome, macropain) subunit, beta type, 5 0.215147
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) 0.214576
NLRX1 NLR family member X1 0.212936
PRELP proline/arginine-rich end leucine-rich repeat protein 0.212761
ANO6 anoctamin 6 0.212586
WNT3A wingless-type MMTV integration site family, member 3A 0.212586
HSPB1 heat shock 27kDa protein 1 0.194507
MIR184 microRNA 184 0.191301
BIN3 bridging integrator 3 0.190616
ANKRD1 ankyrin repeat domain 1 (cardiac muscle) 0.186648
PCYT1A phosphate cytidylyltransferase 1, choline, alpha 0.186011
CHRDL2 chordin-like 2 0.185816
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) 0.185525
CDK11A cyclin-dependent kinase 11A 0.185465
GDF15 growth differentiation factor 15 0.184081
BCAR3 breast cancer anti-estrogen resistance 3 0.18375
GRAP2 GRB2-related adaptor protein 2 0.183648
HMGN2 high mobility group nucleosomal binding domain 2 0.18361
WNT8A wingless-type MMTV integration site family, member 8A 0.183114
MIR31 microRNA 31 0.182994
ACOT7 acyl-CoA thioesterase 7 0.181497
MIR222 microRNA 222 0.180981
SPPL3 signal peptide peptidase like 3 0.18017
CHKA choline kinase alpha 0.179075
WNT9A wingless-type MMTV integration site family, member 9A 0.178585
RYR1 ryanodine receptor 1 (skeletal) 0.177188
MBNL1 muscleblind-like splicing regulator 1 0.176832
WNT16 wingless-type MMTV integration site family, member 16 0.176116
NPTXR neuronal pentraxin receptor 0.175179
LIG3 ligase III, DNA, ATP-dependent 0.174626
TPT1 tumor protein, translationally-controlled 1 0.173618
SLC2A14 solute carrier family 2 (facilitated glucose transporter), member 14 0.173461
AQP11 aquaporin 11 0.173212
P2RX2 purinergic receptor P2X, ligand gated ion channel, 2 0.173198
AQP10 aquaporin 10 0.173171
TEN1 TEN1 CST complex subunit 0.172767
UBB ubiquitin B 0.17256
MSN moesin 0.172435
PIKFYVE phosphoinositide kinase, FYVE finger containing 0.172213
ATG3 autophagy related 3 0.171595
MYC v-myc avian myelocytomatosis viral oncogene homolog 0.170835
PPP2CB protein phosphatase 2, catalytic subunit, beta isozyme 0.169085
AREG amphiregulin 0.168801
TPI1 triosephosphate isomerase 1 0.168218
PPP1CB protein phosphatase 1, catalytic subunit, beta isozyme 0.167619
SMARCA5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 0.167584
SLC23A2 solute carrier family 23 (ascorbic acid transporter), member 2 0.166218
DKK2 dickkopf WNT signaling pathway inhibitor 2 0.165679
MBTPS2 membrane-bound transcription factor peptidase, site 2 0.165601
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha 0.165483
WNT5B wingless-type MMTV integration site family, member 5B 0.165267
SOX13 SRY (sex determining region Y)-box 13 0.164927
ZEB2 zinc finger E-box binding homeobox 2 0.164825
CDK8 cyclin-dependent kinase 8 0.16243
ELOVL6 ELOVL fatty acid elongase 6 0.162341
PISD phosphatidylserine decarboxylase 0.161458
YY1 YY1 transcription factor 0.161066
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme 0.161066
WNT2B wingless-type MMTV integration site family, member 2B 0.160735
RNH1 ribonuclease/angiogenin inhibitor 1 0.160307
CD1E CD1e molecule 0.159969
COASY CoA synthase 0.157857
GALT galactose-1-phosphate uridylyltransferase 0.155957
DKK3 dickkopf WNT signaling pathway inhibitor 3 0.154493
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble 0.154034
CBR1 carbonyl reductase 1 0.153857
WNT7A wingless-type MMTV integration site family, member 7A 0.153709
COIL coilin 0.15273
ERF Ets2 repressor factor 0.151818
PRCD progressive rod-cone degeneration 0.150629
PTGDS prostaglandin D2 synthase 21kDa (brain) 0.148612
OPTN optineurin 0.148579
CLNS1A chloride channel, nucleotide-sensitive, 1A 0.14774
CA12 carbonic anhydrase XII 0.147297
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) 0.146922
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast) 0.14682
COL9A1 collagen, type IX, alpha 1 0.146575
SIX5 SIX homeobox 5 0.14654
MYL9 myosin, light chain 9, regulatory 0.146084
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide 0.145944
LRRC25 leucine rich repeat containing 25 0.145734
CHRD chordin 0.144769
BEST1 bestrophin 1 0.144012
SLC16A8 solute carrier family 16 (monocarboxylate transporter), member 8 0.142976
HEPH hephaestin 0.142416
SLC13A3 solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3 0.14234
CTNND1 catenin (cadherin-associated protein), delta 1 0.141045
WASH7P WAS protein family homolog 7 pseudogene 0.140305
SP3 Sp3 transcription factor 0.140267
WASH1 WAS protein family homolog 1 0.140033
ADRA2A adrenoceptor alpha 2A 0.139994
FCGRT Fc fragment of IgG, receptor, transporter, alpha 0.1398
WASH6P WAS protein family homolog 6 pseudogene 0.139483
MINK1 misshapen-like kinase 1 0.139083
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit 0.138884
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain) 0.138043
ABCB4 ATP-binding cassette, sub-family B (MDR/TAP), member 4 0.137634
EYA2 EYA transcriptional coactivator and phosphatase 2 0.137552
DAXX death-domain associated protein 0.137348
AQP6 aquaporin 6, kidney specific 0.137307
EFNA5 ephrin-A5 0.136487
SREBF2 sterol regulatory element binding transcription factor 2 0.136487
NLN neurolysin (metallopeptidase M3 family) 0.136361
OPLAH 5-oxoprolinase (ATP-hydrolysing) 0.136361
NID2 nidogen 2 (osteonidogen) 0.135901
RDH5 retinol dehydrogenase 5 (11-cis/9-cis) 0.135817
RPE65 retinal pigment epithelium-specific protein 65kDa 0.135817
NRCAM neuronal cell adhesion molecule 0.135274
LTBP3 latent transforming growth factor beta binding protein 3 0.135148
HADHB hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit 0.135065
HSD17B10 hydroxysteroid (17-beta) dehydrogenase 10 0.135023
DOCK5 dedicator of cytokinesis 5 0.134723
GUCY2C guanylate cyclase 2C 0.134466
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2 0.13438
PRSS50 protease, serine, 50 0.134295
NPR1 natriuretic peptide receptor 1 0.134252
CALCB calcitonin-related polypeptide beta 0.13344
GJB6 gap junction protein, beta 6, 30kDa 0.133397
SLCO2A1 solute carrier organic anion transporter family, member 2A1 0.133047
ADRB2 adrenoceptor beta 2, surface 0.132872
EPHB3 EPH receptor B3 0.132784
KCNN3 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 3 0.132697
TPM3 tropomyosin 3 0.13191
TBPL1 TBP-like 1 0.13191
NPS neuropeptide S 0.131866
CTNNA2 catenin (cadherin-associated protein), alpha 2 0.131378
EPHA4 EPH receptor A4 0.131378
GTF3A general transcription factor IIIA 0.131199
ACADVL acyl-CoA dehydrogenase, very long chain 0.13111
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.130931
WNT5A wingless-type MMTV integration site family, member 5A 0.130038
CLIC1 chloride intracellular channel 1 0.129354
PRDX5 peroxiredoxin 5 0.128762
LMNB2 lamin B2 0.128443
GNB3 guanine nucleotide binding protein (G protein), beta polypeptide 3 0.12826
GPR55 G protein-coupled receptor 55 0.128074
APEH acylaminoacyl-peptide hydrolase 0.128074
ATOH7 atonal homolog 7 (Drosophila) 0.127842
CBX5 chromobox homolog 5 0.127795
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 0.127795
GJB3 gap junction protein, beta 3, 31kDa 0.127516
SYP synaptophysin 0.127469
NOTO notochord homeobox 0.127423
MTNR1A melatonin receptor 1A 0.127005
SGK1 serum/glucocorticoid regulated kinase 1 0.126634
FZD8 frizzled class receptor 8 0.126352
MGEA5 meningioma expressed antigen 5 (hyaluronidase) 0.126067
PHB prohibitin 0.12602
BMPR1A bone morphogenetic protein receptor, type IA 0.12583
MTNR1B melatonin receptor 1B 0.125735
POU4F3 POU class 4 homeobox 3 0.125546
DVL3 dishevelled segment polarity protein 3 0.125498
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1 0.125073
EFNA2 ephrin-A2 0.124694
AANAT aralkylamine N-acetyltransferase 0.124356
BTG3 BTG family, member 3 0.124308
AKAP17A A kinase (PRKA) anchor protein 17A 0.124211
DKK1 dickkopf WNT signaling pathway inhibitor 1 0.123729
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7 0.123247
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1 0.122812
CD63 CD63 molecule 0.122419
LDHB lactate dehydrogenase B 0.122272
SEPT4 septin 4 0.122223
TMOD4 tropomodulin 4 (muscle) 0.122125
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 0.121781
SLC12A1 solute carrier family 12 (sodium/potassium/chloride transporter), member 1 0.121732
PVRL2 poliovirus receptor-related 2 (herpesvirus entry mediator B) 0.121536
CYB5A cytochrome b5 type A (microsomal) 0.121487
EGFR epidermal growth factor receptor 0.121487
TGM1 transglutaminase 1 0.121389
ADGRL3 adhesion G protein-coupled receptor L3 0.121389
PLCG1 phospholipase C, gamma 1 0.121193
NKD1 naked cuticle homolog 1 (Drosophila) 0.121144
KLF6 Kruppel-like factor 6 0.121095
LDHC lactate dehydrogenase C 0.120998
TBP TATA box binding protein 0.120948
ASPH aspartate beta-hydroxylase 0.120598
ETNK1 ethanolamine kinase 1 0.120398
MTO1 mitochondrial tRNA translation optimization 1 0.120299
NR3C2 nuclear receptor subfamily 3, group C, member 2 0.120249
TNMD tenomodulin 0.120149
OSCAR osteoclast associated, immunoglobulin-like receptor 0.119999
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa 0.119949
CD53 CD53 molecule 0.119949
MPP5 membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5) 0.11975
FPR1 formyl peptide receptor 1 0.119601
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 0.119451
TUB tubby bipartite transcription factor 0.119302
CELF2 CUGBP, Elav-like family member 2 0.118697
CDK1 cyclin-dependent kinase 1 0.118545
NUMA1 nuclear mitotic apparatus protein 1 0.118545
SPDEF SAM pointed domain containing ETS transcription factor 0.118495
ADORA2A adenosine A2a receptor 0.118393
SMAD9 SMAD family member 9 0.11814
CD6 CD6 molecule 0.118089
UBE2L3 ubiquitin-conjugating enzyme E2L 3 0.118039
PHB2 prohibitin 2 0.117583
FZD6 frizzled class receptor 6 0.117533
PTCH2 patched 2 0.117482
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) 0.117179
IMPA1 inositol(myo)-1(or 4)-monophosphatase 1 0.116973
SFRP5 secreted frizzled-related protein 5 0.116716
SLC6A7 solute carrier family 6 (neurotransmitter transporter), member 7 0.11651
SRRM2 serine/arginine repetitive matrix 2 0.116459
CUL1 cullin 1 0.116408
HIST1H2AD histone cluster 1, H2ad 0.116305
HIST1H2AJ histone cluster 1, H2aj 0.116305
HIST1H2AH histone cluster 1, H2ah 0.116253
CTTN cortactin 0.116202
H2AFJ H2A histone family, member J 0.116151
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase) 0.115996
APOPT1 apoptogenic 1, mitochondrial 0.115894
H2AFY2 H2A histone family, member Y2 0.115842
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class) 0.115688
RDX radixin 0.115637
NLE1 notchless homolog 1 (Drosophila) 0.115637
HIST1H2AM histone cluster 1, H2am 0.115586
H2AFB2 H2A histone family, member B2 0.115535
H2AFB1 H2A histone family, member B1 0.115535
H2AFV H2A histone family, member V 0.115483
MIR26B microRNA 26b 0.115381
HIST1H2AG histone cluster 1, H2ag 0.115381
ZEB1 zinc finger E-box binding homeobox 1 0.115329
SPTAN1 spectrin, alpha, non-erythrocytic 1 0.115278
GADD45A growth arrest and DNA-damage-inducible, alpha 0.115227
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 0.11481
PYCR1 pyrroline-5-carboxylate reductase 1 0.11481
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) 0.11481
CHD7 chromodomain helicase DNA binding protein 7 0.11481
FOXO4 forkhead box O4 0.114706
HSF1 heat shock transcription factor 1 0.114653
UHRF1 ubiquitin-like with PHD and ring finger domains 1 0.114653
HIST1H2AB histone cluster 1, H2ab 0.114601
HIST1H2AE histone cluster 1, H2ae 0.114601
PRKG1 protein kinase, cGMP-dependent, type I 0.114549
DOCK1 dedicator of cytokinesis 1 0.114497
ELAVL2 ELAV like neuron-specific RNA binding protein 2 0.114445
BNC1 basonuclin 1 0.114393
GALR1 galanin receptor 1 0.114341
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) 0.11408
STK39 serine threonine kinase 39 0.11408
FLVCR2 feline leukemia virus subgroup C cellular receptor family, member 2 0.114028
CRABP1 cellular retinoic acid binding protein 1 0.11382
TGS1 trimethylguanosine synthase 1 0.113664
C6ORF25 chromosome 6 open reading frame 25 0.113248
NDST1 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 0.113248
ITGB8 integrin, beta 8 0.11309
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) 0.113037
POMP proteasome maturation protein 0.112931
EDA ectodysplasin A 0.112614
ITGB6 integrin, beta 6 0.112509
BCL2L1 BCL2-like 1 0.112192
LECT1 leukocyte cell derived chemotaxin 1 0.112139
CDC42 cell division cycle 42 0.112139
TXNIP thioredoxin interacting protein 0.111981
TIMP3 TIMP metallopeptidase inhibitor 3 0.111981
H2AFY H2A histone family, member Y 0.111876
KRT7 keratin 7, type II 0.111823
DVL2 dishevelled segment polarity protein 2 0.11177
MCHR1 melanin-concentrating hormone receptor 1 0.111718
SCRIB scribbled planar cell polarity protein 0.111665
NBN nibrin 0.111507
PDGFRB platelet-derived growth factor receptor, beta polypeptide 0.111244
BMPR1B bone morphogenetic protein receptor, type IB 0.11103
ANXA2 annexin A2 0.110923
LMNA lamin A/C 0.110817
OPRK1 opioid receptor, kappa 1 0.110549
CLDN1 claudin 1 0.110442
UBE2I ubiquitin-conjugating enzyme E2I 0.109909
EDNRA endothelin receptor type A 0.109909
HMOX1 heme oxygenase 1 0.109802
TIMP2 TIMP metallopeptidase inhibitor 2 0.109642
ADAM23 ADAM metallopeptidase domain 23 0.109535
CLDN7 claudin 7 0.109482
CDK2 cyclin-dependent kinase 2 0.109482
CD37 CD37 molecule 0.109429
ITGB7 integrin, beta 7 0.109375
STX8 syntaxin 8 0.109269
CXCL6 chemokine (C-X-C motif) ligand 6 0.109216
HAS3 hyaluronan synthase 3 0.108892
ELL elongation factor RNA polymerase II 0.108622
DFFA DNA fragmentation factor, 45kDa, alpha polypeptide 0.108352
ITGA6 integrin, alpha 6 0.108298
HIPK2 homeodomain interacting protein kinase 2 0.108028
GNG8 guanine nucleotide binding protein (G protein), gamma 8 0.107704
MAP1LC3B microtubule-associated protein 1 light chain 3 beta 0.107704
MEIS2 Meis homeobox 2 0.107381
BMP2K BMP2 inducible kinase 0.107219
AQP8 aquaporin 8 0.107219
SDHAF2 succinate dehydrogenase complex assembly factor 2 0.107165
ACVR1 activin A receptor, type I 0.107002
FGF8 fibroblast growth factor 8 (androgen-induced) 0.106948
CALD1 caldesmon 1 0.106948
PXDN peroxidasin 0.106838
FABP7 fatty acid binding protein 7, brain 0.106675
DUT deoxyuridine triphosphatase 0.10662
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.10662
MATN1 matrilin 1, cartilage matrix protein 0.106511
MLANA melan-A 0.106456
DACH1 dachshund family transcription factor 1 0.106402
TFPI2 tissue factor pathway inhibitor 2 0.106293
IDS iduronate 2-sulfatase 0.106293
FBLL1 fibrillarin-like 1 0.106238
SMAD7 SMAD family member 7 0.106238
SLC1A7 solute carrier family 1 (glutamate transporter), member 7 0.106074
NPPB natriuretic peptide B 0.10602
SPAG7 sperm associated antigen 7 0.10602
PFKM phosphofructokinase, muscle 0.10602
CDON cell adhesion associated, oncogene regulated 0.105965
ARNT aryl hydrocarbon receptor nuclear translocator 0.105856
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 0.105802
TYRO3 TYRO3 protein tyrosine kinase 0.105693
GLO1 glyoxalase I 0.105421
PTTG1 pituitary tumor-transforming 1 0.105203
PLEC plectin 0.105149
NGB neuroglobin 0.104875
MIRLET7C microRNA let-7c 0.104875